Abstract:
BACKGROUND:Anthracycline-induced cardiotoxicity remains a significant and unresolved issue in patients receiving chemotherapy. The aim of this study was to evaluate left ventricular (LV) twisting function by three-dimensional speckle tracking echocardiography (3D-STE) in patients with lymphoma after anthracycline therapy. METHODS:One hundred and one patients with newly diagnosed diffuse large B-cell lymphoma who had planned to receive anthracycline chemotherapy were enrolled. LV apical rotation, basal rotation, twist, torsion, time to peak apical rotation and time to peak basal rotation were measured by 3D-STE at baseline, after the completion of two cycles and four cycles of the regimen, respectively. Apical-basal rotation delay was calculated as the difference between time to basal and time to apical rotation. RESULTS:The results showed that LV apical rotation, basal rotation, twist and torsion declined progressively during the whole procedure (baseline vs. two and four cycles of the regimen, apical rotation: 12.5 ± ± 4.5° vs. 8.8 ± 3.6° vs. 6.0 ± 3.2°; basal rotation: -7.7 ± 3.0° vs. -5.9 ± 2.6° vs. -4.4 ± 2.5°; twist: 20.0 ± 6.4° vs. 14.5 ± 5.1° vs. 9.8 ± 4.5°; torsion: 2.9 ± 0.9°/cm vs. 2.1 ± 0.9°/cm vs. 1.4 ± 0.7°/cm; all p < 0.01). Furthermore, apical-basal rotation delay increased significantly after two cycles as well as after four cycles of the regimen (38.3 ± 67.9 ms vs. 66.7 ± 73.9 ms vs. 92.6 ± 96.9 ms; p < 0.01). CONCLUSIONS:LV twisting function deteriorated in the early stage of anthracycline therapy in patients with lymphoma, which could be detected by 3D-STE sensitively.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Song F,Kang Y,Zhang C,Xu Y,Shi J,Guo Y,Zhang Q,Shu X,Cheng Ldoi
10.5603/CJ.a2017.0035subject
Has Abstractpub_date
2017-01-01 00:00:00pages
484-494issue
5issn
1897-5593pii
VM/OJS/J/49928journal_volume
24pub_type
杂志文章abstract:BACKGROUND:The additional purpose for pacemaker implantation, beyond treating arrhythmias and conduction disturbances, is to improve the quality of life (QoL) of the patient. Most previous research has shown this purpose to have been achieved. However, the question as to whether all mental and physical components impro...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:In those without symptoms of coronary artery disease (CAD), the incidence of coronary events is still high. The aim of this study was to evaluate whether flow mediated dilatation (FMD) is a useful tool in identifying those with CAD in who are under 45 years of age. METHODS AND RESULTS:Seventy five men below...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Reduced heart rate variability (HRV) is associated with a poor outcome in patients with sinus rhythm (SR) or atrial fibrillation (AF). However, cut-off points for HRV measures differ between SR and AF. We hypothesized that a global index of 24-hour HRV based on evaluation of scatterplot would describe HRV ir...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0010
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Beta-catenin has been implicated in cell-cell communication in a wide variety of developmental and physiological processes. Defective Wnt signaling could result in various cardiac and vascular abnormalities. Little is known regarding Wnt/frizzled pathway in cardiomyocyte apoptosis. METHODS:In this study, th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0087
更新日期:2017-01-01 00:00:00
abstract::Mediastinitis is a well-known complication of open heart surgery. Abscess as late complication, presenting years after heart surgery, is adegnotical. Transthoracic needle biopsies of lung parenchyma guided by computer tomography are widely accepted. The puncture of periaortic masses is not routinely performed. We repo...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2014.0045
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Although atrial fibrillation (AF) ablation is considered a technically challenging procedure, studies on the learning curve of different pulmonary vein isolation (PVI) techniques are limited. We investigated the time-dependent changes in procedural parameters, complication rates, and in the 1-year clinical o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0085
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Evaluating prospectively the feasibility, accuracy and reproducibility of optical flow ratio (OFR), a novel method of computational physiology based on optical coherence tomography (OCT). METHODS AND RESULTS:Sixty consecutive patients (76 vessels) underwent prospectively OCT, angiography- based quantitative...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0071
更新日期:2020-01-01 00:00:00
abstract::The prevalence of diabetes mellitus (DM) is growing worldwide. Prothrombotic and proinflammatory states, in adjunct to endothelial dysfunction and metabolic disorders, such as hyperglycemia, dyslipidemia, obesity, insulin resistance, and oxidative stress, are key features of the accelerated atherosclerotic progression...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.2013.0090
更新日期:2013-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Objective of this study was to make an assessment of standard functional and defor-mation parameters (strain) in patients after transcatheter aortic valve replacement (TAVR) by cardiac magnetic resonance imaging (CMR) and the evaluation of their prognostic impact. METHODS:Patients undergoing TAVR received C...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0121
更新日期:2018-01-01 00:00:00
abstract::Patients with complete interruption of the aortic arch (IAA) very rarely reach late adulthood without having undergone surgical intervention. Only a few cases of IAA in adults have been reported in the medical literature. In this case report, we present a late diagnosis of interrupted aortic arch in a 68 year-old male...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0036
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Recently, it has been hypothesized that type 2 diabetes might interfere with acute intravenous thrombolysis effectiveness as estimated by angiographic or electrocardiographic criteria. In our study, we compared the thrombolytic effect of streptokinase infusion between diabetic and non-diabetic myocardial inf...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0029
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Primary percutaneous coronary intervention (PCI) is recommended for ST-segment elevation myocardial infarction (STEMI) patients even when the patient must be transported to a PCI-capable hospital. This study aimed to evaluate the long-term clinical outcomes of STEMI patients who were transferred for primary ...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2016.0003
更新日期:2016-01-01 00:00:00
abstract::Upstream therapy is the promising issue in the treatment of atrial fibrillation (AF) especially in patients with arterial hypertension and heart failure. The possible beneficial effects of renin-angiotensin-aldosterone system blockade with ACE-inhibitors and angiotensin receptor antagonists in AF prevention have been ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/cj.2012.0043
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The profile of subjects undergoing percutaneous mitral balloon valvuloplasty (PMBV) in developed countries has shifted toward the elderly. In the group of elderly patients long-term results after PMBV, as well prognostic factors that may improve patient selection for this procedure have not been fully elucid...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0008
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The present study of patients with Wenckebach-type second-degree sinoatrial block (W-block) evaluated the probability of the development of a more advanced grade of sinoatrial block. Data on the clinical significance of W--block are limited. It is unknown whether W-block predicts a more advanced grade of sin...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The aim of the study was to evaluate the role of cardiopulmonary exercise testing (CPET) parameters in assessing exercise capacity improvement after percutaneous pulmonary valve implantation (PPVI). Additionally, it aimed to determine if there are any baseline characteristics influencing that change. METHOD...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0013
更新日期:2015-01-01 00:00:00
abstract::n/a - brief communication. ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2019.0099
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Awareness of risks associated with radiation exposure to patients and medical staff has significantly increased. It has been reported before that the use of advanced three-dimensional electroanatomical mapping (EAM) system significantly reduces fluoroscopy time, however this study aimed for zero or near zero...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0029
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Data regarding the outcome of patients with ventricular tachyarrhythmias related to arterial hypertension (AHT) and smoking is limited. The study sought to assess the prognostic impact of AHT and smoking on survival in patients presenting with ventricular tachyarrhythmias. METHODS:All consecutive patients s...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0158
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Although it has been realized that restrictive mitral valve annuloplasty (MVA) may re-sult in clinically significant functional mitral stenosis (MS), it still cannot be predicted. The purpose of this study was to identify risk factors for clinically significant functional MS following restrictive MVA surgery...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0023
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Red cell distribution width (RDW) in acute heart failure (AHF) is accepted as a prognostic indicator with unclear pathophysiological ties. The aim of this study was to evaluate the prognostic value of RDW in AHF patients in relation to clinical and echocardiographic data. METHODS:170 patients with AHF were ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0103
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The associations between statin and coronary plaque compositional changes were re-ported according to the use of high dose or not. An evaluation of the impact of low-density lipoprotein cholesterol (LDL-C) < 70 mg/dL by using real world dosages of statin on coronary plaque composition was undertaken. METHOD...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0002
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Aspirin remains the mainstay of anti-platelet therapy in cardiac patients. However, if a patient is allergic to aspirin and dual anti-platelet therapy is indicated - such as with percutaneous coronary intervention (PCI), then there is no clear guidance. One possibility is aspirin desensitization. A variety o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0025
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Antiplatelet therapy has proven beneficial in the treatment of cardiovascular disease. Proton pump inhibitors (PPIs) are commonly used for gastroprotection in patients receiving antiplatelet therapy. Several trials have been carried out to establish interactions between PPIs, clopidogrel and soluble formulat...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Research on cardiac rehabilitation has raised interesting methods and effects without however establishing the share of the profits according to age, sex and cardiac pathology. Yet today, this disease with various pathologies strikes people of all ages and both sexes, and the recommended rehabilitation exerc...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0026
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Left ventricular non-compaction cardiomyopathy (LVNC) features extensive trabeculations. Involvement of the right ventricle (RV) has been reported; however, distinction from normal RV trabeculation is difficult. This study aimed at assessing RV morphology and function in LVNC by cardiac magnetic resonance (C...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0095
更新日期:2020-07-10 00:00:00
abstract::The identification of high-risk patients with hypertrophic cardiomyopathy (HC) for primary prevention of sudden cardiac death (SCD) remains a challenging issue, since major risk factors sometimes lack specificity. We report the case of a patient with HC and association of apical aneurysm and myocardial bridging who...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0119
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Water immersion may cause adverse cardiovascular events, including arrhythmias in patients with damaged cardiac muscle, e.g. with cardiac failure. So far, there have been rather few reports on arrhythmia induced by water training in patients with coronary artery disease (CAD). The aim of the study was to ass...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0065
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Pulmonary arterial hypertension is of importance in congenital cardiac surgery as being a significant cause of morbidity and mortality. Although therapy options are limited, inhaled nitric oxide (NO) is used as a standard therapy. The present study aimed to compare inhaled NO and aerosolized iloprost in chil...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:10.5603/cj.2012.0070
更新日期:2012-01-01 00:00:00