Abstract:
BACKGROUND:Atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with an increased risk of ischemic stroke. The aim of this study was to compare the clinical characteristics, the incidence of left atrial appendage (LAA) thrombus and its predictors, and spontaneous echo contrast (SEC) in a population of patients with AF depending on estimated glomerular filtration rate (eGFR) values. METHODS:This study included 1962 patients who underwent transesophageal echocardiographic examination (TEE) prior to cardioversion or ablation in the years 2014-2018 in three cardiac centers. RESULTS:More than a quarter of AF patients had decreased eGFR ( < 60 mL/min/1.73 m²) and were characterized as a high-risk population, with more comorbidities, higher thromboembolic and bleeding risk compared to those with normal renal function. Oral anticoagulation (OAC) was prescribed in 97% and 93% of patients with decreased and normal eGFR, respectively, with a higher prevalence of prescribed non-vitamin K antagonist oral anticoagulants (NOACs). The incidence of LAA thrombus (24%, 9% and 4%) and SEC (25%, 25% and 19%) increases simultaneously with a decrease in eGFR ( < 30, 30-59 and > 60 mL/min/1.73 m², respectively). Among patients prescribed reduced doses of NOAC, those with decreased eGFR were more often observed with LAA thrombus (10% vs. 2.5%). Non-paroxysmal AF, heart failure and previous bleeding were predictors of LAA thrombus, irrespective of eGFR value. CKD was the predictor of LAA thrombus in all patients including those with non-paroxysmal AF, males, without diabetes, without hypertension and with CHA₂DS₂-VASc < 2. CONCLUSIONS:Despite OAC, patients with concomitant AF and CKD remain at high risk for LAA thrombus formation.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Budnik M,Gawałko M,Gorczyca I,Uziębło-Życzkowska B,Krzesiński P,Kochanowski J,Scisło P,Michalska A,Jelonek O,Starzyk K,Jurek A,Kiliszek M,Wożakowska-Kapłon B,Gielerak G,Filipiak KJ,Opolski G,Kapłon-Cieślicka Adoi
10.5603/CJ.a2020.0036subject
Has Abstractpub_date
2020-04-27 00:00:00issn
1897-5593pii
VM/OJS/J/67047pub_type
杂志文章abstract:BACKGROUND:AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) is a prospective, multicenter study designed with the aim of describing the prevalence and epidemiology of AF practice in Turkey. This study aims to evaluate stroke risk in non-valvular atrial fibrillation (AF) and anticoagulant drug utilization w...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2013.0055
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Antiplatelet therapy has proven beneficial in the treatment of cardiovascular disease. Proton pump inhibitors (PPIs) are commonly used for gastroprotection in patients receiving antiplatelet therapy. Several trials have been carried out to establish interactions between PPIs, clopidogrel and soluble formulat...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The presence of psoriasis is currently considered by the European Society of Cardiology cardiovascular prevention guidelines of 2016 as one possible cardiovascular risk factor. Patients with psoriasis and concomitant coronary artery disease treated by means of percutaneous coronary interven-tion (PCI) are a ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0076
更新日期:2020-01-01 00:00:00
abstract::Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::We report a case of typical counterclockwise atrial flutter (AFL) with conduction block from right to left atrium along the coronary sinus (CS) musculature, confirmed by discontinuous CS activation sequence during pacing near the ostium and differential right atrial pacing. AFL was associated with an atypical flutter ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Prediction of functional myocardial recovery post acute myocardial infarction should be based not only on flow patency of the infarct related artery (IRA) but also on the quality of microcirculation in at-risk segments. Myocardial blush grade (MBG) is a method of perfusion assessment which has an established...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Objective of this study was to make an assessment of standard functional and defor-mation parameters (strain) in patients after transcatheter aortic valve replacement (TAVR) by cardiac magnetic resonance imaging (CMR) and the evaluation of their prognostic impact. METHODS:Patients undergoing TAVR received C...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0121
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The impact of final Thrombolysis in Myocardial Infarction (TIMI) flow in the infarct-related artery (IRA) on outcomes in non-ST-segment elevation myocardial infarc-tion (NSTEMI) patients treated with percutaneous coronary intervention (PCI) is unknown. This study aimed to evaluate the impact of post-procedur...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2016.0025
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Myocardial dysfunction needing inotropic support is a typical complication after on-pump cardiac surgery. In this study, we evaluate the effect of milrinone on patients with ventricular dysfunction undergoing coronary artery bypass graft (CABG). METHODS:Seventy patients with impaired left ventricular functi...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The Amplatzer Amulet (St. Jude Medical, Minneapolis, MN, USA) is a second gen-eration Amplatzer device for left atrial appendage (LAA) occlusion (LAAO) for stroke prophylaxis in patients with atrial fibrillation. This research sought to assess the clinical performance of the Amplatzer Amulet device and in fo...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0017
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Evaluating prospectively the feasibility, accuracy and reproducibility of optical flow ratio (OFR), a novel method of computational physiology based on optical coherence tomography (OCT). METHODS AND RESULTS:Sixty consecutive patients (76 vessels) underwent prospectively OCT, angiography- based quantitative...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0071
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Ultrasonic tissue characterization (UTC) has been widely used to investigate left ventricular (LV) dysfunction in various cardiac disorders. The aim of this study was to investigate the correlation between functional capacity and UTC in patients with idiopathic dilated cardiomyopathy (IDCM). METHODS AND RES...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0082
更新日期:2013-01-01 00:00:00
abstract::This image showed tension pneumopericardium caused by removing the pericardiocentesis catheter, which was inserted to drain malignant pericardial effusion. Tension pneumopericardium is a rare and potentially fatal event. Mortality from tension pneumopericardium can be as high as 50%. Therefore, it is important to susp...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Although it has been realized that restrictive mitral valve annuloplasty (MVA) may re-sult in clinically significant functional mitral stenosis (MS), it still cannot be predicted. The purpose of this study was to identify risk factors for clinically significant functional MS following restrictive MVA surgery...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0023
更新日期:2019-01-01 00:00:00
abstract::Diabetic ketoacidosis is a major cause of morbidity and mortality in patients with insulin dependent diabetes. Myocardial infarction is an uncommon but well-recognised precipitating cause of diabetic ketoacidosis, accounting for 1% of cases. Many diabetic patients with ketoacidosis initially present with hyperkelamia,...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Takotsubo syndrome (TTS) is still a relatively understudied and often undetected disease. It is usually preceded by emotional or physical triggers. We here report a case of TTS following a car accident. Typical apical ballooning with moderate reduction of left ventricular ejection fraction (LVEF) and increased level o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2016.0034
更新日期:2016-01-01 00:00:00
abstract::Despite advances in pharmacological treatments aimed at a neurohormonal blockade for heart failure, there is still a growing number of patients with advanced symptoms who suffer significant morbidity and mortality. At present the most effective cure for end-stage congestive heart failure is cardiac transplantation. Th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The meta-analysis was aimed to compare the long time (> 2 year) clinical outcomes of limus-based stents (LBS) and paclitaxel-eluting stents (PES). LBS and PES are two kinds of most common coronary artery stents in clinics. METHODS:Electronic data bases of PubMed, Cochrane, and EMBASE were searched. We inclu...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2014.0004
更新日期:2014-01-01 00:00:00
abstract::Coronary stent loss and its migration is one of complications of percutaneous coronary interventions (PCI). We present a case of successful retrieval of a coronary stent which moved initially to the left renal artery. Subsequently the stent was lost again and migrated to the left deep femoral artery, while an attempt ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The aim of the study was to identify differences between proximal and distal cell rewir-ing with subsequent kissing balloon inflation (KBI) in the presence of a link connected to a carina on the jailed side branch ostium (SBO). METHODS:Kaname stents were deployed in bifurcation models (n = 12) with subseque...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0076
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Beta-catenin has been implicated in cell-cell communication in a wide variety of developmental and physiological processes. Defective Wnt signaling could result in various cardiac and vascular abnormalities. Little is known regarding Wnt/frizzled pathway in cardiomyocyte apoptosis. METHODS:In this study, th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0087
更新日期:2017-01-01 00:00:00
abstract::Upstream therapy is the promising issue in the treatment of atrial fibrillation (AF) especially in patients with arterial hypertension and heart failure. The possible beneficial effects of renin-angiotensin-aldosterone system blockade with ACE-inhibitors and angiotensin receptor antagonists in AF prevention have been ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/cj.2012.0043
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Long non-coding RNAs (lncRNAs) have been confirmed to be involved in the pathologi-cal processes of multiple diseases. However, the characteristic expression of lncRNAs in peripheral blood of coronary artery disease (CAD) patients and whether some of these lncRNAs can be used as diagnostic biomarkers for CAD...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0133
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM). METHODS:We studied 204 patients treated with elective or emergent coronar...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Catheter entrapment due to severe radial artery spasm (RAS) during transradial coronary catheterization has been rarely reported and its management is not precisely defined. The aim of this study was to determine the incidence, predictors and management of catheter entrapment due to severe RAS. METHODS:A to...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0022
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Pulmonary hypertension is a contradiction for heart transplantation (HTx). The aim of the study was to examine prognostic significance of pulmonary hemodynamic variables in patients with severe chronic heart failure (HF) considered for HTx. METHODS:Patients with HF were qualified to HTx in Poland. We measur...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2014.0015
更新日期:2014-01-01 00:00:00
abstract::A case of a 26-year-old man without continuity of blood flow in the level of the isthmus of the aorta is described. During interventional catheterization, we reconstructed this continuity and implanted a vascular stent. ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Osteoprotegerin (OPG) is a member of the tumor necrosis factor superfamily.Recent evidence supports a relationship between serum OPG level and atherosclerosis. The aim of this study was to evaluate the possible association of OPG with the presence of coronary artery disease (CAD), its severity and prognosis ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0071
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Implantable loop recorders (ILR) are a valuable tool for the investigation of unexplainedsyncopal episodes. The aim of this retrospective single center study was to identify predictive factors for pacemaker implantation in patients with unexplained syncope who underwent ILR insertion. METHODS:One hundred si...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0008
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Coronary arteriography is still widely accepted as a gold standard for the diagnosis of coronary artery disease (CAD), despite emerging methods such as multi-slice computed tomography. None of the presently available non-invasive diagnostic tests is perfect. The aim of the article was to make a comparison of...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00