Modulation of feedback-related negativity during trial-and-error exploration and encoding of behavioral shifts.

abstract：:Posterior parietal cortex is frequently activated during episodic memory retrieval but its role during retrieval and its interactions with the hippocampus are not yet clear. In this fMRI study, we investigated the neural bases of recognition memory when study repetitions and retrieval goals were manipulated. During en...

journal_title：Frontiers in neuroscience

authors： Ciaramelli E,Burianová H,Vallesi A,Cabeza R,Moscovitch M

更新日期：2020-11-03 00:00:00

abstract：:The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For...

journal_title：Frontiers in neuroscience

authors： Plis SM,Sarwate AD,Wood D,Dieringer C,Landis D,Reed C,Panta SR,Turner JA,Shoemaker JM,Carter KW,Thompson P,Hutchison K,Calhoun VD

更新日期：2016-08-19 00:00:00

abstract：:Environmental sounds form part of our daily life. With the advancement of deep learning models and the abundance of training data, the performance of automatic sound classification (ASC) systems has improved significantly in recent years. However, the high computational cost, hence high power consumption, remains a ma...

journal_title：Frontiers in neuroscience

authors： Wu J,Chua Y,Zhang M,Li H,Tan KC

更新日期：2018-11-19 00:00:00

abstract：:The auditory cortex integrates auditory information over time to obtain neural representations of sound events, the time scale of which critically affects perception. This work investigated the species differences in the time scale of integration by comparing humans and monkeys regarding how their scalp-recorded corti...

journal_title：Frontiers in neuroscience

authors： Itoh K,Nejime M,Konoike N,Nakamura K,Nakada T

更新日期：2019-06-24 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：:A vital feature in the success of Ecdysozoa is their ability to shed their exoskeleton (a process called ecdysis) such that they can grow or change their morphology. In holometabolous insects, these behaviors are orchestrated by the sequential actions of neuropeptides, one of which is crustacean cardioactive peptide (...

journal_title：Frontiers in neuroscience

authors： Lee D,Orchard I,Lange AB

更新日期：2013-11-05 00:00:00

abstract：:Environmental stressors including protein malnutrition (PMN) during pre-, neo- and post-natal age have been documented to affect cognitive development and cause increased susceptibility to neuropsychiatric disorders. Most studies have addressed either of the three windows and that does not emulate the clinical conditi...

journal_title：Frontiers in neuroscience

authors： Naik AA,Patro IK,Patro N

更新日期：2015-12-08 00:00:00

abstract：:Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53bp1 in both develop...

journal_title：Frontiers in neuroscience

authors： Müller B,Ellinwood NM,Lorenz B,Stieger K

更新日期：2018-05-01 00:00:00

abstract：:Alzheimer's disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal area. In the present study, cholinergic cell death was induced by in...

journal_title：Frontiers in neuroscience

authors： Dobryakova YV,Volobueva MN,Manolova AO,Medvedeva TM,Kvichansky AA,Gulyaeva NV,Markevich VA,Stepanichev MY,Bolshakov AP

更新日期：2019-03-12 00:00:00

abstract：:Our team has been a pioneer in harvesting extracellular vesicles (EVs) enriched for neuronal origin from peripheral blood and using them as a biomarker discovery platform for neurological disorders. This methodology has demonstrated excellent diagnostic and predictive performance for Alzheimer's and other neurodegener...

journal_title：Frontiers in neuroscience

authors： Mustapic M,Eitan E,Werner JK Jr,Berkowitz ST,Lazaropoulos MP,Tran J,Goetzl EJ,Kapogiannis D

更新日期：2017-05-22 00:00:00

abstract：:Gene Expression Programming (GEP), a variant of Genetic Programming (GP), is a well established technique for automatic generation of computer programs. Due to the flexible representation, GEP has long been concerned as a classification algorithm for various applications. Whereas, GEP cannot be extended to multi-class...

journal_title：Frontiers in neuroscience

authors： Wei T,Zhong J

更新日期：2020-01-17 00:00:00

abstract：:Understanding the complex neural mechanisms controlling urinary bladder activity is an extremely important topic in both neuroscience and urology. Simultaneously recording of the bladder activity and neural activity in related brain regions will largely advance this field. However, such recording approach has long bee...

journal_title：Frontiers in neuroscience

authors： Yao J,Li Q,Li X,Qin H,Liang S,Liao X,Chen X,Li W,Yan J

更新日期：2019-06-25 00:00:00

abstract：:Neural stem cells-based therapies have shown great potential for central nervous system regeneration, with three-dimensional (3D) culture systems representing a key technique for tissue engineering applications, as well as disease modeling and drug screenings. Self-assembling peptides (SAPs), providing biomimetic synt...

journal_title：Frontiers in neuroscience

authors： Marchini A,Favoino C,Gelain F

更新日期：2020-05-05 00:00:00

abstract：:Transcutaneous Vagus Nerve Stimulation (tVNS) on the auricular branch of the vagus nerve has been receiving attention due to its therapeutic potential for neuropsychiatric disorders. Although the mechanism of tVNS is not yet completely understood, studies have demonstrated the potential role of vagal afferent nerve st...

journal_title：Frontiers in neuroscience

authors： Jin Y,Kong J

更新日期：2017-01-20 00:00:00

abstract：:The growing interest in intrinsic brain organization has sparked various innovative approaches to generating comprehensive connectivity-based maps of the human brain. Prior reports point to a sexual dimorphism of the structural and functional human connectome. However, it is uncertain whether subtle changes in sex hor...

journal_title：Frontiers in neuroscience

authors： Arélin K,Mueller K,Barth C,Rekkas PV,Kratzsch J,Burmann I,Villringer A,Sacher J

更新日期：2015-02-23 00:00:00

abstract：:Identifying the multiple contributors to the audiometric loss of a hearing impaired (HI) listener at a particular frequency is becoming gradually more useful as new treatments are developed. Here, we infer the contribution of inner (IHC) and outer hair cell (OHC) dysfunction to the total audiometric loss in a sample o...

journal_title：Frontiers in neuroscience

authors： Johannesen PT,Pérez-González P,Lopez-Poveda EA

更新日期：2014-07-23 00:00:00

abstract：:Asiatic acid (AA), a pentacyclic triterpene derived from the tropical medicinal plant Centella asiatica, has been widely used as an antioxidant and anti-inflammatory agent. Evidence regarding the neuroprotective properties of AA is emerging. However, the protective effects of AA and its mechanism in glaucoma are poorl...

journal_title：Frontiers in neuroscience

authors： Huang W,Gao F,Hu F,Huang J,Wang M,Xu P,Zhang R,Chen J,Sun X,Zhang S,Wu J

更新日期：2018-07-20 00:00:00

abstract：:In the event-related potential (ERP) of scalp electroencephalography (EEG) studies, the vertex reference (Cz), linked mastoids or ears (LM), and average reference (AVG) are popular reference methods, and the reference electrode standardization technique (REST) is increasingly applied. Because scalp EEG recordings are ...

journal_title：Frontiers in neuroscience

authors： Dong L,Liu X,Zhao L,Lai Y,Gong D,Liu T,Yao D

更新日期：2019-10-11 00:00:00

abstract：:Modern high field and ultra high field magnetic resonance imaging (MRI) experiments routinely collect multi-dimensional data with high spatial resolution, whether multi-parametric structural, diffusion or functional MRI. While diffusion and functional imaging have benefited from recent advances in multi-dimensional si...

journal_title：Frontiers in neuroscience

authors： Bazin PL,Alkemade A,van der Zwaag W,Caan M,Mulder M,Forstmann BU

更新日期：2019-10-09 00:00:00

abstract：:Diffusible ions (Na+, K+, Mg2+, Ca2+, Cl-) are vital for healthy function of all cells, especially brain cells. Unfortunately, the diffusible nature of these ions renders them difficult to study with traditional microscopy in situ within ex vivo brain tissue sections. This mini-review examines the recent progress in t...

journal_title：Frontiers in neuroscience

authors： Hartnell D,Andrews W,Smith N,Jiang H,McAllum E,Rajan R,Colbourne F,Fitzgerald M,Lam V,Takechi R,Pushie MJ,Kelly ME,Hackett MJ

更新日期：2020-01-22 00:00:00

abstract：:Neurogenesis, the process of generating new neurons in the brain, fascinates researchers for its promise to affect multiple cognitive and functional processes in both health and disease. Many cellular pathways are involved in the regulation of neurogenesis, a complexity exemplified by the extensive regulation of this ...

journal_title：Frontiers in neuroscience

authors： Barak B,Feldman N,Okun E

更新日期：2014-08-28 00:00:00

abstract：:Spinal cord edema, mainly including vasogenic and cytotoxic edema, influences neurological outcome after spinal cord contusion (SCC). Aquaporin 4 (AQP4) is the most ubiquitous water channel in the central nervous system (CNS), which is a rate-limiting factor in vasogenic edema expressing in brain injury, and it contri...

journal_title：Frontiers in neuroscience

authors： Huang Y,Li SN,Zhou XY,Zhang LX,Chen GX,Wang TH,Xia QJ,Liang N,Zhang X

更新日期：2019-06-14 00:00:00

abstract：:Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disease, yet available pharmacological treatments are largely ineffective due, in part, to an inadequate understanding of the neurobiological drivers that underpin the condition. The recent resurgence of research into the clinical applications of ...

journal_title：Frontiers in neuroscience

authors： Foldi CJ,Liknaitzky P,Williams M,Oldfield BJ

更新日期：2020-02-04 00:00:00

abstract：:This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC) cochlear model. The CAR part simulates the basilar membrane's (BM) response to sound. The FAC part models the outer hair cell (OHC), the inner hair cell (IHC), and the medial olivocochlear effere...

journal_title：Frontiers in neuroscience

authors： Xu Y,Thakur CS,Singh RK,Hamilton TJ,Wang RM,van Schaik A

更新日期：2018-04-10 00:00:00

abstract：:Although, cochlear implants (CI) traditionally have been used to treat individuals with bilateral profound sensorineural hearing loss, a recent trend is to implant individuals with residual low-frequency hearing. Notably, many of these individuals demonstrate an air-bone gap (ABG) in low-frequency, pure-tone threshold...

journal_title：Frontiers in neuroscience

authors： Koka K,Saoji AA,Attias J,Litvak LM

更新日期：2017-04-18 00:00:00

abstract：:Adult hippocampal neurogenesis (AHN) in the dentate gyrus is known to respond to environmental enrichment, chronic stress, and many other factors. The function of AHN may vary across the septo-temporal axis of the hippocampus, as different subdivisions are responsible for different functions. The dorsal pole regulates...

journal_title：Frontiers in neuroscience

authors： Gualtieri F,Brégère C,Laws GC,Armstrong EA,Wylie NJ,Moxham TT,Guzman R,Boswell T,Smulders TV

更新日期：2017-09-15 00:00:00

abstract：:Understanding the effects of environmental stimulation in autism can improve therapeutic interventions against debilitating sensory overload, social withdrawal, fear and anxiety. Here, we evaluate the role of environmental predictability on behavior and protein expression, and inter-individual differences, in the valp...

journal_title：Frontiers in neuroscience

authors： Favre MR,La Mendola D,Meystre J,Christodoulou D,Cochrane MJ,Markram H,Markram K

更新日期：2015-06-02 00:00:00

abstract：Background:Cochlear implants (CIs) are auditory prostheses designed to support spoken communication in persons with severe to profound hearing loss. Many post-lingually deaf adult CI users achieve good speech recognition in quiet; unfortunately, CI technology conveys a degraded representation of pitch and timbre, essen...

journal_title：Frontiers in neuroscience

authors： Gfeller K,Mallalieu RM,Mansouri A,McCormick G,O'Connell RB,Spinowitz J,Gellinek Turner B

更新日期：2019-12-24 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms throughout adult life in most of the affected patients. This unfavorable course is associated with multiple episodes and residual symptoms, mainly negative symptoms and cognitive deficits. The neural diathesis-stress model proposes that p...

journal_title：Frontiers in neuroscience

authors： Popovic D,Schmitt A,Kaurani L,Senner F,Papiol S,Malchow B,Fischer A,Schulze TG,Koutsouleris N,Falkai P

更新日期：2019-03-21 00:00:00

abstract：:Background: Significant progress toward the recovery of useful vision in blind patients with severe degenerative retinal diseases caused by photoreceptor death has been achieved with the development of visual prostheses that stimulate the retina electrically. However, currently used prostheses do not provide feedback ...

journal_title：Frontiers in neuroscience

authors： Rincón Montes V,Gehlen J,Lück S,Mokwa W,Müller F,Walter P,Offenhäusser A

更新日期：2019-04-30 00:00:00