Abstract:
:This article reviews the current knowledge on drug-induced movement disorders (DIMD) epidemiology, pathophysiology, phenomenology and treatment. This review is justified by its high prevalence in certain medical specialties, the need to include them on movement disorders etiologic differential diagnosis and the potential economical burden. The acronym DIMD refers to a heterogeneous group of neurological syndromes, the most prevalent being parkinsonism, dystonia, dyskinesia and akathisia. Soon after neuroleptics (D2 dopamine receptor blocking agents) introduction in clinical practice, the first acute dystonic reactions were reported. Later, was recognized that extrapyramidal symptoms could occur in association with their chronic use. Nowadays, several non dopamine receptor blocking drugs and drugs of abuse are recognized as potential inductors of extrapyramidal reactions.
journal_name
Acta Med Portjournal_title
Acta medica portuguesaauthors
Damásio J,Carvalho Ssubject
Has Abstractpub_date
2011-12-01 00:00:00pages
915-22eissn
0870-399Xissn
1646-0758journal_volume
24 Suppl 4pub_type
杂志文章,评审abstract::Twelve cases of extreme umbilical blood flow impairement (8 cases with loss of end-diastolic blood flow and 4 cases with reversed flow) found among 658 pregnancies studied by continuous Doppler between April 1st 1989 and March 31st 1990, are reported. The findings were associated to intra-uterine growth retardation (9...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:INTRODUCTION:Perfectionism and intolerance to frustration are the main factors of vulnerability to psychological stress observed in students of the Integrated Master Degree in Medicine of the Faculty of Medicine, University of Coimbra, a study claims. We aimed to ascertain their reasons, seeking for their prevention. ...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:10.20344/amp.9976
更新日期:2018-10-31 00:00:00
abstract::Stevens-Johnson syndrome and toxic epidermal necrolysis are potentially life-threatening adverse cutaneous drug reactions. Clinically, it manifests as a rash, often morbilliform, or atypical target lesions that evolve to epidermal detachment. There is mucosal involvement in almost all patients. The loss of skin's barr...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:2011-12-01 00:00:00
abstract:INTRODUCTION:The disruption of esophageal motility that characterizes achalasia typically provokes dysphagia, pain, loss of weight and malnutrition. Therefore, patients frequently report a reduction in quality of life and negative emotional states. Laparoscopic Heller myotomy proved to be an effective therapy, enabling...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:10.20344/amp.6758
更新日期:2016-02-01 00:00:00
abstract:UNLABELLED:In Portugal, there have been many studies on the prevalence of overweight and obesity in children and adolescents. However, because many of the studies are not submitted to publication in scientific journals, these results remain unknown. OBJECTIVE:To obtain recent data on the prevalence of overweight and o...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:2011-03-01 00:00:00
abstract::Sympathetic and parasympathetic nervous system evaluation was performed in 21 patients with rheumatoid arthritis. Every patient had autonomic nervous system (ANS) dysfunction, the parasympathetic involvement being the most frequent. ANS dysfunction may explain some manifestations and may well be the expression of a la...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::In an attempt to discern the paradigms underlying our medical practice (more specifically paediatrics) over the last 30 years, it was found that these are rather similar to the ones prevailing at the beginning of this period--all wrong-doings were attributed to outside forces which had to be neutralized; the obsession...
journal_title:Acta medica portuguesa
pub_type: 历史文章,杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Differentiated thyroid carcinoma of follicular origin (DTCFO), although not very frequent, has registered a raising incidence in the last decades. In the majority of the cases, DTCFO is a curable disease when treated and monitored by experienced, multidisciplinary teams. These factors contribute to an increasing numbe...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,实务指引,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:UNLABELLED:Tobacco smoking is the cause of more than half million deaths/year in the European Union (EU). Monitoring smoking prevalence is an important tool to evaluate the epidemic and its evolution and to assess the effectiveness of preventive measures. The comparison between countries may help us identify good contr...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract::Since the introduction of imatinib mesylate for the treatment of chronic myeloid leukaemia, impressive clinical responses were observed in the majority of patients in chronic phase. However, not all patients experience an optimal response to imatinib mesylate or even to the more potent, second generation tyrosine kina...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:2013-07-01 00:00:00
abstract::The occurrence of metastases is documented in a varied number of hepato-cellular carcinomas (HCC). The indicative metastasis is very rarely the form of clinical presentation of the disease. Two cases of HCC which were clinically presented in a secondary location, in the bone and skeletal muscle respectively, are descr...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::Sepsis is a common pathology during the neonatal period. Low-birth weight is the most important isolated risk factor. With the purpose of determining the prevalence of nosocomial infection in newborns of very low birth weight (VLBW), finding the microbial flora and the mortality of these patients, the authors retrospe...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::In this article we reviewed some examples of our experience in clinical applications of functional MRI (fMRI) in the motor and verbal fluency tasks evaluation. Seventeen patients with supratentorial cerebral pathology (5 arteriovenous malformations--AVMs, 2 meningiomas, 1 tuberculoma, 1 cortical tuberoma, 1 DNET, 2 ce...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Schistosomiasis is a major cause of liver damage and portal hypertension, especially in tropical countries, affecting about 200 million people in the world. We report the cases of two patients presenting persistent alterations of serum liver enzymes. We enhance the importance of considering the history of past travels...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocy...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2016-05-01 00:00:00
abstract::Malignant spinal cord compression occurs in 2.5% - 5% cancer patients. Early diagnosis and therapeutic intervention are critical for pain control and improvement of any neurological deficit. Treatment should be directed to the underlying disease together with appropriate symptom management. The case of a man with tetr...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2012-11-01 00:00:00
abstract::The authors join the celebrations of the Centenary of the establishment of the Faculdade de Medicina da Universidade de Lisboa, on the 22(nd) April 2011, through the historical account of one of its main pilasters, the Institute of Anatomy. It is discussed the scope of its creation at the time, the important work done...
journal_title:Acta medica portuguesa
pub_type: 历史文章,杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION:Meningococcal disease has a wide spectrum of clinical presentation. Occult bacteremia is not easily diagnosed and may have good prognostic. CLINIC REPORT:Three year-old African boy with fever, gonalgia and gait disorder with 24 hours of evolution. Observation was unremarkable. He presented leukocytosis (2...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract::Temporal arteritis is a systemic vasculitis mainly affecting large and medium sized vessels, temporal artery in particular. The authors report the case of a male who presented with large painful scalp ulcers over the temporo-parietal area, ipsilateral headache, amaurosis fugax and jaw claudication. Temporal arteries w...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Some families fulfilling the Amsterdam Criteria (AC) differ from the Lynch syndrome (LS) in that colorectal cancers (CRC) do not present microsatellite instability (MSI) and DNA mismatch repair gene mutations are not found. These families have been designated as Familial Colorectal Cancer type X (XS) and the...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::Correct food intake and physical exercise, together with insulin or oral antidiabetics constitute the basic triad of diabetes treatment. The authors discuss the general rules of dietetic measures in diabetes and review the importance of physical exercise, its indications and limitations in the metabolic control of the...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00
abstract::Cutaneous cytomegalovirus (CMV) infection has been observed in a variety of nonspecific skin lesions. Because of this fact, its diagnosis is rare and frequently accidental. The presence of the virus has also been observed in apparently normal skin, from both a clinical and histological point of view. In this context, ...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-01 00:00:00
abstract::Stent appears as the most recent and revolutionary acquisition in Endovascular Surgery. It represents the percutaneous permanent placement of a Vascular prosthesis. We discuss its background and evolution, the several types as well as some of its characteristics as biocompatibility, trombogenicity and biomechanics. We...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1991-09-01 00:00:00
abstract::Endoscopic interventional techniques have created a wide new perspective for non-surgical treatment of chronic pancreatitis (CP). Surgery and endoscopy differ in their techniques, but are comparable with regard to tactics. The aim of methods in CP is to relieve pain and/or local complications. The preliminary results ...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1995-06-01 00:00:00
abstract::Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare disorder of unknown cause, associated with intense and abnormal eosinophilic lung infiltration. Most cases occur in patients with prior history of atopy and asthma. It is characterized by subacute or chronic presentation, alveolar and blood eosinophilia and pe...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:The recent occurrence of a number of outbreaks of dengue in Portuguese speaking countries with no previous disease, aroused curiosity about the competing factors for the phenomenon and a need for better knowledge of the pathology. We review the dengue-related situation in Portuguese speaking countries, lin...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease's prognosis. The Systemic Lupus International Collaborating Clinics/ Systemic Damage Index defines systemic lupus erythematosus disease severity and is found to predict pro...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:10.20344/amp.8082
更新日期:2017-05-31 00:00:00
abstract::The authors report the clinical case of a woman exposed to ionizing radiotherapy, for the treatment of breast carcinoma, in whom a pemphigus lesion developed within the area of irradiation. This is, to the authors' knowledge, the 14th case of ionizing radiation-induced pemphigus. ...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:The Power of Food Scale measures appetite for, rather than consumption of, palatable foods - a construct frequently designated as hedonic hunger. The purpose of this study was to examine the psychometric properties of a Portuguese version of the Power of Food Scale, namely reliability and construct validit...
journal_title:Acta medica portuguesa
pub_type: 杂志文章
doi:10.20344/amp.6517
更新日期:2015-09-01 00:00:00
abstract::The interaction between HPV E6 and p53 protein is known as the most important event in HPV-associated carcinogenesis. Some in vitro studies suggested that p53 genetic variants are targeted for ubiquitin-proteasome degradation induced by E6 with different abilities. A common p53 variant at position 72 (R72P) has leaded...
journal_title:Acta medica portuguesa
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00