Optic neuritis and retinal ganglion cell loss in a chronic murine model of multiple sclerosis.

abstract：:Background: External ventricular drain (EVD) has a major role in the management and monitoring of intracranial pressure (ICP) and its major complication is EVD infection. The risk factors for EVD infection are still a major topic of controversy, hence the need for further research. Objective: The objective of this rev...

journal_title：Frontiers in neurology

authors： Sorinola A,Buki A,Sandor J,Czeiter E

更新日期：2019-03-15 00:00:00

abstract：:Ornithine transcarbamylase deficiency (OTCD) is the most common form of urea cycle disorder characterized by the presence of hyperammonemia (HA). In patients with OTCD, HA is known to cause impairments in domains of executive function and working memory. Monitoring OTCD progression and investigating neurocognitive bio...

journal_title：Frontiers in neurology

authors： Anderson AA,Gropman A,Le Mons C,Stratakis CA,Gandjbakhche AH

更新日期：2020-08-14 00:00:00

abstract：:Objective: The aims of this study were to compare the characteristics of three motor subtype classifications in patients with de novo Parkinson's disease (PD) and to find the most suitable motor subtype classification for identifying non-motor symptoms (NMSs). Methods: According to previous studies, a total of 256 pat...

journal_title：Frontiers in neurology

authors： Ren J,Hua P,Li Y,Pan C,Yan L,Yu C,Zhang L,Xu P,Zhang M,Liu W

更新日期：2020-12-23 00:00:00

abstract：OBJECTIVE:To perform two scoping systematic reviews of the literature on cytokine measurement in: 1. cerebral microdialysis (CMD) and 2. cerebrospinal fluid (CSF) in severe traumatic brain injury (TBI) patients. METHODS:Two separate systematic reviews were conducted: one for CMD cytokines and the second for CSF cytoki...

journal_title：Frontiers in neurology

authors： Zeiler FA,Thelin EP,Czosnyka M,Hutchinson PJ,Menon DK,Helmy A

更新日期：2017-07-10 00:00:00

abstract：:Background: Intracranial atherosclerotic stenosis (ICAS) is an important cause of ischemic stroke. In Asians, intracranial atherosclerotic disease leads to 33-50% of ischemic events. At present, treatment with medication vs. endovascular therapy (EVT) for symptomatic ICAS (sICAS) patients is still debatable. The clini...

journal_title：Frontiers in neurology

authors： Zhang J,Zhang K,Jia B,Qi Z,Mo D,Ma N,Gao F,Miao Z

更新日期：2020-11-06 00:00:00

abstract：:Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are kno...

journal_title：Frontiers in neurology

authors： Hirokawa Y,Fujimoto A,Ichikawa N,Sato K,Tanaka T,Enoki H,Otsuki Y,Okanishi T

更新日期：2019-06-12 00:00:00

abstract：:Different subtypes of Alzheimer's disease (AD) with characteristic distributions of neurofibrillary tangles and corresponding brain atrophy patterns have been identified using structural magnetic resonance imaging (MRI). However, the underlying biological mechanisms that determine this differential expression of neuro...

journal_title：Frontiers in neurology

authors： Ferreira D,Pereira JB,Volpe G,Westman E

更新日期：2019-05-28 00:00:00

abstract：:Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal stenosis and the hemodynamic significance of middle cerebral artery (MCA) steno...

journal_title：Frontiers in neurology

authors： Fang H,Leng X,Pu Y,Zou X,Pan Y,Song B,Soo YOY,Leung TWH,Wang C,Zhao X,Wang Y,Wang Y,Wong KS,Liu L,Xu Y,CICAS Study Group.

更新日期：2020-04-15 00:00:00

abstract：:Traumatic brain injury is the leading cause of death in children. Children with severe TBI are in need of neurointensive care where the goal is to prevent secondary brain injury by avoiding secondary insults. Monitoring of cerebral blood flow (CBF) and autoregulation in the injured brain is crucial. However, there are...

journal_title：Frontiers in neurology

authors： Rostami E,Nilsson P,Enblad P

更新日期：2020-04-16 00:00:00

abstract：Introduction:There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal designs. Aim:We investigated the differences in cognitive decline in AD compared to DLB over 4 ye...

journal_title：Frontiers in neurology

authors： Breitve MH,Chwiszczuk LJ,Brønnick K,Hynninen MJ,Auestad BH,Aarsland D,Rongve A

更新日期：2018-03-06 00:00:00

abstract：:Introduction: Today, half of the American homeless population is older than 50 years of age. This shift in age distribution among people experiencing homelessness has challenged our long-held views of the causes of homelessness. Age-related neurological diseases, especially neurodegenerative diseases of the brain (NDD...

journal_title：Frontiers in neurology

authors： Piña-Escudero SD,López L,Sriram S,Longoria Ibarrola EM,Miller B,Lanata S

更新日期：2021-01-13 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:Background: Over the last few years there has been growing interest in use of visual measures as useful tools for multiple sclerosis (MS) prognosis and tracking. Optic neuritis (ON) being a prevalent and often-presenting symptom of the disease, as well as the high occurrence rate of posterior visual system damage inde...

journal_title：Frontiers in neurology

authors： Backner Y,Petrou P,Glick-Shames H,Raz N,Zimmermann H,Jost R,Scheel M,Paul F,Karussis D,Levin N

更新日期：2019-05-03 00:00:00

abstract：:Background: The forefront treatment of Parkinson's disease (PD) is Levodopa. When patients are treated with Levodopa cerebral blood flow is increased while cerebral metabolic rate is decreased in key subcortical regions including the putamen. This phenomenon is especially pronounced in patients with Levodopa-induced d...

journal_title：Frontiers in neurology

authors： Aljuaid M,Booth S,Hobson DE,Borys A,Williams K,Katako A,Ryner L,Goertzen AL,Ko JH

更新日期：2019-11-21 00:00:00

abstract：:Background: Perinatal and perioperative brain injury is a fundamental problem in infants with severe congenital heart disease undergoing neonatal cardiac surgery with cardiopulmonary bypass. An impaired neuromotor and neurocognitive development is encountered and associated with a reduction in quality of life. New neu...

journal_title：Frontiers in neurology

authors： Stegeman R,Lamur KD,van den Hoogen A,Breur JMPJ,Groenendaal F,Jansen NJG,Benders MJNL

更新日期：2018-07-03 00:00:00

abstract：:Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) is a localization-independent neurotransmitter of the entire nervous system. Reduced levels of SP were found in saliva of pa...

journal_title：Frontiers in neurology

authors： Schröder JB,Marian T,Claus I,Muhle P,Pawlowski M,Wiendl H,Suntrup-Krueger S,Meuth SG,Dziewas R,Ruck T,Warnecke T

更新日期：2019-04-16 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2018.01033.]. ...

journal_title：Frontiers in neurology

authors： VanElzakker MB,Brumfield SA,Lara Mejia PS

更新日期：2020-09-17 00:00:00

abstract：:The pattern of epileptic seizures is often considered unpredictable and the interval between events without correlation. A number of studies have examined the possibility that seizure activity respects a power-law relationship, both in terms of event magnitude and inter-event intervals. Such relationships are found in...

journal_title：Frontiers in neurology

authors： Cook MJ,Varsavsky A,Himes D,Leyde K,Berkovic SF,O'Brien T,Mareels I

更新日期：2014-10-24 00:00:00

abstract：:The mechanisms involved in traumatic brain injury have yet to be fully characterized. One mechanism that, especially in high-energy trauma, could be of importance is cavitation. Cavitation can be described as a process of vaporization, bubble generation, and bubble implosion as a result of a decrease and subsequent in...

journal_title：Frontiers in neurology

authors： Cao Y,Risling M,Malm E,Sondén A,Bolling MF,Sköld MK

更新日期：2016-02-01 00:00:00

abstract：:Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent retriever (SR) thr...

journal_title：Frontiers in neurology

authors： Chuming H,Yifan H,Ke X,Chukai X,Weijie Z,Hui L,Guoyi P,Xiaoyong Z,Peifeng Z,Chuwei C

更新日期：2020-10-22 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a non-destructive technique that is capable of localizing pathologies and assessing other anatomical features (e.g., tissue volume, microstructure, and white matter connectivity) in postmortem, ex vivo human brains. However, when brains are removed from the skull and cerebrospinal f...

journal_title：Frontiers in neurology

authors： Shatil AS,Matsuda KM,Figley CR

更新日期：2016-11-29 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:Background: Palliative care in Parkinson's Disease (PD) patients considerably differs from palliative care in oncology patients. Integrated care models are a concept to support patients and improve management of PD symptoms. However, it is not known if the access to PD patients at the end of life can be achieved throu...

journal_title：Frontiers in neurology

authors： Eggers C,Dano R,Schill J,Fink GR,Timmermann L,Voltz R,Golla H,Lorenzl S

更新日期：2018-07-30 00:00:00

abstract：:Cognitive dysfunction is a significant non-motor feature of Parkinson's disease, with the risk of dementia increasing with prolonged disease duration. Multiple cognitive domains are affected, and the pathophysiology cannot be explained by dopaminergic loss alone. Sophisticated neuroimaging techniques can detect the na...

journal_title：Frontiers in neurology

authors： Sasikumar S,Strafella AP

更新日期：2020-01-31 00:00:00

abstract：:Seizures are an infrequent and serious neurological complication of SARS-CoV-2 infection, with limited data describing the etiology and the clinical context in which these occur or the associated electrographic and imaging findings. This series details four cases of seizures occurring in patients with COVID-19 with di...

journal_title：Frontiers in neurology

authors： Hwang ST,Ballout AA,Mirza U,Sonti AN,Husain A,Kirsch C,Kuzniecky R,Najjar S

更新日期：2020-11-05 00:00:00

abstract：:Epilepsy is associated with abnormal spatiotemporal changes in resting-state brain connectivity, but how these changes are characterized in interhemispheric coupling remains unclear. This study aimed to characterize frequency-dependent alterations in voxel-wise mirrored homotopic connectivity (VMHC) measured by restin...

journal_title：Frontiers in neurology

authors： Jiang L,Ma X,Li S,Luo H,Zhang G,Wang Y,Zhang T

更新日期：2020-07-29 00:00:00

abstract：UNLABELLED:α(2)-adrenoceptors (AR) lower central sympathetic output and peripheral catecholamine release, thereby protecting against sympathetic hyperactivity and hypertension. Norepinephrine re-uptake-transporter effectively (NET) removes norepinephrine from the synapse. Overflow to plasma will therefore not reflect r...

journal_title：Frontiers in neurology

authors： Berg T,Walaas SI,Roberg BÅ,Huynh TT,Jensen J

更新日期：2012-11-08 00:00:00

abstract：CONTEXT:Mandibular movements (MM) are considered as reliable reporters of respiratory effort (RE) during sleep and sleep disordered breathing (SDB), but MM accuracy has never been validated against the gold standard diaphragmatic electromyography (EMG-d). OBJECTIVES:To assess the degree of agreement between MM and EMG...

journal_title：Frontiers in neurology

authors： Martinot JB,Le-Dong NN,Cuthbert V,Denison S,Silkoff PE,Guénard H,Gozal D,Pepin JL,Borel JC

更新日期：2017-07-21 00:00:00

abstract：:Intensive glycemic control has not shown consistent findings in stroke prevention for diabetes patients, particularly for those with microvascular complications. This case-control study evaluates the risks of stroke in Asian diabetic population with microvascular complications. From the insurance claims of Taiwan, we ...

journal_title：Frontiers in neurology

authors： Lo SF,Chen WL,Muo CH,Chen PC,Chen SY,Kuo CL,Sung FC

更新日期：2018-08-29 00:00:00

abstract：INTRODUCTION:Options currently available to individuals with upper limb loss range from prosthetic hands that can perform many movements, but require more cognitive effort to control, to simpler terminal devices with limited functional abilities. We attempted to address this issue by designing a myoelectric control sys...

journal_title：Frontiers in neurology

authors： Gailey A,Artemiadis P,Santello M

更新日期：2017-02-01 00:00:00