Abstract:
:Alcohol consumption is a risk indicator for periodontal disease. The purpose of this study was to morphometrically evaluate the influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats. Thirty-six female rats (Wistar, 120 days-old) were randomly divided into three groups that received a daily administration of a water diet (control, n = 12), a 10% alcohol diet (10% ethanol, n = 12) or a 20% alcohol diet (20% ethanol, n = 12). Four weeks after the onset of the experiment, cotton ligatures were placed around the cervix of the upper right second molar in six rats. The other 6 rats in each group remained unligated. The rats were sacrificed four weeks after ligature placement. The maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at 2 buccal and 2 palatal sites on the upper right second molar. Analyses between the ligated and unligated groups showed that the presence of ligature induced alveolar bone loss (p < 0.05). Unligated groups showed no significant differences between each other (p > 0.05). In the ligated groups, rats receiving 20% ethanol showed significantly greater bone loss compared to control rats or rats receiving 10% ethanol. These results demonstrate that alcohol consumption may increase alveolar bone loss in female rats in a dose-dependent manner.
journal_name
Braz Oral Resjournal_title
Brazilian oral researchauthors
Souza DM,Ricardo LH,Kantoski KZ,Rocha RFdoi
10.1590/s1806-83242009000300017subject
Has Abstractpub_date
2009-07-01 00:00:00pages
326-32issue
3eissn
1806-8324issn
1807-3107pii
S1806-83242009000300017journal_volume
23pub_type
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abstract::[This corrects the article doi: 10.1590/1807-3107BOR-2017.vol31.0105]. ...
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doi:10.1590/1807-3107BOR-2017.vol31.0105erratum
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journal_title:Brazilian oral research
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journal_title:Brazilian oral research
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journal_title:Brazilian oral research
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journal_title:Brazilian oral research
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abstract::Fluoride has been widely used in dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury to genetic material. Genotoxicity tests represent an important part of cancer research to assess the risk of potenti...
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