Abstract:
:The effects of ethanol alone on the oral mucosa are still poorly understood, especially because there are few non-smoking chronic consumers of alcoholic beverages. The aim of this study was to evaluate the frequency of micronucleus, abnormal nucleus/cytoplasm ratio, pyknosis, karyorrhexis and karyolysis in exfoliated cells from the buccal mucosa and from the lateral border of the tongue in 36 non-smoker alcoholics (ethanol group) and 18 non-smokers and non-drinkers (control group). The Papanicolaou method was used. Since alcoholics generally have hepatobiliary involvement, the association between serum gamma-glutamyl transpeptidase (GGT) and some of the analyzed oral mucosa alterations was also investigated. The ethanol group showed a significant increase in the frequency of all alterations analyzed in the tongue cells when compared with the control group (p < 0.01; Mann-Whitney). However, the presence of these changes in buccal mucosa cells was not statistically significant (p > 0.05; Mann-Whitney). In the ethanol group, the correlation between serum GGT and the frequency of micronucleus and abnormal nucleus/cytoplasm ratio in oral mucosa cells was not significant (p > 0.05; Spearman). In conclusion, chronic exposure to ethanol may be associated with carcinogenic cytologic changes in the oral mucosa, even in the absence of tobacco smoking. These alterations were not correlated with hepatobiliary injury.
journal_name
Braz Oral Resjournal_title
Brazilian oral researchauthors
Reis SR,do Espírito Santo AR,Andrade MG,Sadigursky Mdoi
10.1590/s1806-83242006000200002subject
Has Abstractpub_date
2006-04-01 00:00:00pages
97-102issue
2eissn
1806-8324issn
1807-3107pii
S1806-83242006000200002journal_volume
20pub_type
杂志文章abstract::Halitosis or bad breath is an oral health condition characterized by unpleasant odors emanating consistently from the oral cavity. The origin of halitosis may be related both to systemic and oral conditions, but a large percentage of cases, about 85%, are generally related to an oral cause. Causes include certain food...
journal_title:Brazilian oral research
pub_type: 杂志文章,评审
doi:10.1590/s1806-83242008000500007
更新日期:2008-01-01 00:00:00
abstract::To assess the impact of oral conditions on the oral health-related quality of life (OHRQoL) of pediatric liver transplant candidates. This cross-sectional study included 60 children aged 13 to 48 months who were liver transplant candidates that attended the AC Camargo Cancer Center, São Paulo, Brazil. On the day of or...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2020.vol34.0100
更新日期:2020-01-01 00:00:00
abstract::This study aimed at investigating the effect of the partial erasing of DenOptix system storage phosphor plates on the image quality of digital radiographs. Standardized digital radiographs were acquired of a phantom mandible, using size 2 intraoral DenOptix storage phosphor plates (n = 10). Subsequently, the active ar...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242008000100014
更新日期:2008-01-01 00:00:00
abstract::Although malocclusions represent a serious public health issue, there is insufficient information about this problem in adolescents in Brazil, especially in poorer areas. The purpose of this cross-sectional study was to estimate the prevalence of facial alterations, dental malocclusions, and deleterious oral habits (D...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242012005000027
更新日期:2013-01-01 00:00:00
abstract::This research evaluated the fungistatic and fungicidal activities of red propolis alcoholic extract (RPAE) against different Candida species isolated from chronic periodontitis cases, and compared with chlorhexidine (CHX). Nineteen samples of Candida species (C. albicans [n = 12], C. tropicalis [n = 5] and C. glabrata...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2015.vol29.0083
更新日期:2015-01-01 00:00:00
abstract::This study aimed to analyze the 100 most-cited papers in the field of oral medicine and pathology over time, identifying the areas of more intense research. Papers in journals of oral medicine and pathology were identified using the Web of Science database. The specified research period was between 1900 and 2019. Desc...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2021.vol35.0020
更新日期:2020-12-18 00:00:00
abstract::The purpose of the present study was to evaluate the relationship between psychological variables and the clinical diagnosis of temporomandbular disorders (TMD) in 12-year-old adolescents. TMD pain was assessed by RDC/TMD examination (Research Diagnostic Criteria for Temporomandibular Disorders) (Axis I and II). Five-...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242009000200011
更新日期:2009-04-01 00:00:00
abstract::This study investigated the effect of coinitiator solutions and self-adhesive resin cement on the early retention of glass-fiber posts. Cylindrical glass-fiber posts were luted into 40 incisor roots with different adhesion strategies (n = 10): SB2, Single Bond 2 + conventional resin cement (RelyX ARC); AP, Scotchbond ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242012005000017
更新日期:2012-09-01 00:00:00
abstract::Recent studies on functional tissue regeneration have focused on substances that favor cell proliferation and differentiation, including the bioactive phenolic compounds present in grape seed extract (GSE). The aim of this investigation was to evaluate the stimulatory potential of GSE in the functional activity of und...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2019.vol33.0013
更新日期:2019-02-11 00:00:00
abstract::The present systematic review was performed to investigate if there is evidence justifying the prophylactic extraction of third molars, one of the most frequent procedures in oral surgery. A series of searches was carried out for randomized, clinical trials and systematic reviews in seven databases (MEDLINE, BBO, LILA...
journal_title:Brazilian oral research
pub_type: 杂志文章,评审
doi:
更新日期:2013-03-01 00:00:00
abstract::This in vitro study evaluated both the antimicrobial activity and the root canal cleaning ability of plant extracts used in irrigation solutions. The antimicrobial activities of the aroeira-da-praia (Schinus terebintifolius Raddi) and the quixabeira (Syderoxylum obtusifolium Roem & Schult) hydroalcoholic extracts, of ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242012000300006
更新日期:2012-05-01 00:00:00
abstract::The purpose of this study was to measure mass loss and surface roughness changes of different brands of flowable resin composites after a simulated toothbrushing test. The null hypotheses were that there would be no differences in mass loss and no significant changes in surface roughness after this test and that there...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242004000200012
更新日期:2004-04-01 00:00:00
abstract::The aim of this study was to investigate the prevalence of orofacial clefts in live newborns from 1998 to 2002 in Brazilian state capitals and correlate their occurrence with a number of relevant socioeconomic factors collected in the 2000 census. Data was obtained from the Public Health Hospital Information System (S...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242009000100007
更新日期:2009-01-01 00:00:00
abstract::This study evaluated the effects of 10% alphatocopherol on the fracture resistance of endodontically treated teeth subjected to tooth bleaching with hydrogen peroxide and immediately restored with composite resin. Fifty bovine incisors were selected, including 10 sound teeth that constituted the control group (G1 (C))...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0069
更新日期:2016-05-20 00:00:00
abstract::The aim of this study was to evaluate patient perception of surgical discomfort in third molar surgery and the association with clinical variables and polymorphisms associated with the FKBP5, SLC6A4, and COMT genes. This cross-sectional observational study was carried out on 196 participants aged between 18 and 64 yea...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2021.vol35.0007
更新日期:2020-11-13 00:00:00
abstract::This study aimed at assessing the relationship between dental pain and the reason for using dental services and oral health quality of life in people aged 50 to 74 years in southern Brazil. A cross-sectional population-based study was conducted with 720 individuals aged 50 to 74 years, living in three health districts...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0039
更新日期:2016-08-18 00:00:00
abstract::Frequent use of Xylitol may decrease the S. mutans levels. However, very little is known about whether this effect on the levels of cariogenic bacteria is maintained after the interruption of short-term usage of xylitol. This study aimed at evaluating changes in mutans streptococci (MS) salivary levels after using a c...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242010000200003
更新日期:2010-04-01 00:00:00
abstract::This study evaluated the effect of cleanser solutions on the color of heat-polymerized acrylic resin (HPAR) and on the brightness of dental alloys with 180 immersion trials. Disk-shaped specimens were made with I) commercially pure titanium, II) nickel-chromium-molybdenum-titanium, III) nickel-chromium molybdenum, and...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2014.vol28.0017
更新日期:2014-01-01 00:00:00
abstract::The aim of the present study was to evaluate the prevalence and impact of malocclusion on oral health-related quality of life (OHRQoL) among schoolchildren aged 8 to 10 years and their parents in Diamantina, a town in the southeast of Brazil. A cross-sectional study was conducted with a sample of 390 randomly selected...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2018.vol32.0095
更新日期:2018-01-01 00:00:00
abstract::Poor oral hygiene seems to be the norm in children and teenagers with Down Syndrome (DS). Advances in design and types of toothbrushes may improve biofilm control. This randomized, single-blind, crossover clinical trial evaluated the effectiveness of electric toothbrushes regarding mechanical control of biofilm in chi...
journal_title:Brazilian oral research
pub_type: 杂志文章,随机对照试验
doi:10.1590/1807-3107bor-2020.vol34.0057
更新日期:2020-06-19 00:00:00
abstract::Manufacturers offer various prescriptions of preadjusted brackets for use in the "straight-wire" orthodontic technique. However, the need to incorporate bends in the rectangular wires during orthodontic finishing has led to concerns regarding the type of prescription chosen and the credibility of information provided ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2014.vol28.0038
更新日期:2014-01-01 00:00:00
abstract::This pilot study aimed to evaluate the influence of smoking on clinical and microbiological parameters after nonsurgical periodontal therapy. Forty-eight subjects were grouped into smokers (SM, n = 24) and nonsmokers (NS, n = 24) and paired according to gender, age, ethnicity, and periodontal status. Both groups recei...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0092
更新日期:2016-08-22 00:00:00
abstract::School and family together play an important role in the individual development of children. Therefore, this study aimed at evaluating the practices and attitudes towards oral health care of 245 education professionals working in 24 public municipal pre-schools in Niterói, State of Rio de Janeiro, Brazil. The data wer...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242008000400010
更新日期:2008-10-01 00:00:00
abstract::This randomized clinical trial aimed to assess the efficacy of sealing occlusal carious lesions in permanent teeth. The sample consisted of 54 occlusal carious lesions in permanent molars and premolars of 49 patients aged 8-43 years (median: 19 years). The inclusion criteria comprised the presence of a cavity with no ...
journal_title:Brazilian oral research
pub_type: 杂志文章,随机对照试验
doi:10.1590/1807-3107BOR-2017.vol31.0044
更新日期:2017-06-05 00:00:00
abstract::There is a clear reported association between social disparity and oral health, for example, between dental caries and malnutrition in children. This fact is detected in several studies, and also found amongst the Brazilian population. However, several efforts have been made to improve the quality of life of the popul...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242012000700004
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to evaluate alternative methods for the disinfection of toothbrushes considering that most of the previously proposed methods are expensive and cannot be easily implemented. Two-hundred toothbrushes with standardized dimensions and bristles were included in the study. The toothbrushes were di...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242010000100005
更新日期:2010-01-01 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) has spread exponentially across the world. The typical manifestations of COVID-19 include fever, dry cough, headache and fatigue. However, atypical presentations of COVID-19 are being increasingly reported. Recently, a number of studies have recognized various mucocutaneous manifest...
journal_title:Brazilian oral research
pub_type: 杂志文章,评审
doi:10.1590/1807-3107bor-2020.vol34.0124
更新日期:2020-10-30 00:00:00
abstract::Orofacial pain and temporomandibular dysfunction may cause chronic facial pain, which may interfere with the emotional state and food intake of patients with eating disorders (ED), such as anorexia nervosa (AN) and bulimia nervosa (BN). Sixty-four patients were assigned to four groups: Group A (AN - restricting subtyp...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2018.vol32.0051
更新日期:2018-06-07 00:00:00
abstract::Conventional methods of caries detection, including the gold standard of histological examination, have certain disadvantages that must be addressed prior to validating any other diagnostic technique-current or new. Here we evaluated the validity of micro-computed tomography (micro-CT) as an alternative gold-standard ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2015.vol29.0132
更新日期:2015-01-01 00:00:00
abstract::The purpose of this study was to analyze luxation injuries in children between the ages of 0 and 5 years treated at an emergency service department. A total of 1,703 records, corresponding to a period of 10 years at the Emergency Center of the Baby Clinic at Londrina State University, Brazil, were analyzed. The age, g...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242011000200009
更新日期:2011-03-01 00:00:00