Spinal cord injury and the human microbiome: beyond the brain-gut axis.

abstract：OBJECTIVE:Convection-enhanced delivery (CED) and osmotic pump delivery both have been promoted as promising techniques to deliver drugs to pediatric diffuse intrinsic pontine gliomas (DIPGs). Correspondingly, the aim of this study was to understand how infusate molecular weight (MW), duration of delivery, and mechanism...

journal_title：Neurosurgical focus

authors： Rechberger JS,Power EA,Lu VM,Zhang L,Sarkaria JN,Daniels DJ

更新日期：2020-01-01 00:00:00

abstract：:Cerebral revascularization procedures have been used in the clinical management of actual or threatened cerebral ischemic states and unclippable cerebral aneurysms. An alternative to a low-flow bypass graft (for example, with the superficial temporal artery) is the use of high-flow grafts created using the saphenous v...

journal_title：Neurosurgical focus

authors： Kocaeli H,Andaluz N,Choutka O,Zuccarello M

更新日期：2008-01-01 00:00:00

abstract：OBJECT:The middle third of the clivus and the region around the petrous internal carotid artery (ICA) is a difficult area of the skull base in terms of access. This is a deep area rich with critical neurovascular structures, which is often host to typical skull base diseases. Expanded endoscopic endonasal approaches of...

journal_title：Neurosurgical focus

authors： Kassam AB,Gardner P,Snyderman C,Mintz A,Carrau R

更新日期：2005-07-15 00:00:00

abstract：:OBJECTIVEFew studies have been published specifically examining intravenous drug abuse (IVDA)-associated spinal epidural abscesses (SEAs), an unfortunate sequela of the opioid crisis in the United States. Here, the authors examined a series of patients with IVDA-associated SEAs in order to shed light on this challengi...

journal_title：Neurosurgical focus

authors： DiGiorgio AM,Stein R,Morrow KD,Robichaux JM,Crutcher CL,Tender GC

更新日期：2019-01-01 00:00:00

abstract：:Tumor-associated epilepsy is an important contributor to morbidity in patients with brain tumors. Proposed pathophysiological mechanisms to explain these effects range from neuronal and glial dysfunction to deranged vascular homeostasis, to ionic and pH changes. Perilesional tissue alterations play a vital role in the...

journal_title：Neurosurgical focus

authors： Rajneesh KF,Binder DK

更新日期：2009-08-01 00:00:00

abstract：:Germ line and somatic mutations in the neurofibromatosis Type 2 (NF2) tumor suppressor gene predispose individuals to tumors of the nervous system, including schwannomas and meningiomas. Since identification of the NF2 gene more than a decade ago, a large body of information has been collected on the nature and conseq...

journal_title：Neurosurgical focus

authors： Ruttledge MH,Rouleau GA

更新日期：2005-11-15 00:00:00

abstract：:Chiari malformation is a developmental disorder that is often associated with other abnormalities of the cerebrospinal axis. Despite widespread recognition of this association, there is relatively little information on the treatment of these coexisting disorders in the setting of cerebellar tonsillar ectopia. In an ef...

journal_title：Neurosurgical focus

authors： Greenlee J,Garell PC,Stence N,Menezes AH

更新日期：1999-06-15 00:00:00

abstract：:For many years, the experience of neurosurgeons from the German Armed Forces was limited to the peacetime care of patients in Germany. In 1995, German military neurosurgeons were deployed abroad for the first time. Since the beginning of the International Security Assistance Force mission, there has been a rapidly inc...

journal_title：Neurosurgical focus

authors： Mauer UM,Schulz C,Rothe R,Kunz U

更新日期：2010-05-01 00:00:00

abstract：OBJECT:The authors present a series of 4 patients with rare facial nerve tumors. The relevant literature is reviewed and is discussed regarding diagnostic features, the role of operative management, and surgical approach. METHODS:A retrospective chart review was conducted for patients with tumors of the facial nerve t...

journal_title：Neurosurgical focus

authors： Ross L,Drazin D,Eboli P,Lekovic GP

更新日期：2013-03-01 00:00:00

abstract：OBJECT:A more comprehensive understanding of the epigenetic abnormalities associated with meningioma tumorigenesis, growth, and invasion may provide useful targets for molecular classification and development of targeted therapies for meningiomas. METHODS:The authors performed a review of the current literature to ide...

journal_title：Neurosurgical focus

authors： He S,Pham MH,Pease M,Zada G,Giannotta SL,Wang K,Mack WJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The authors aimed to compare the efficacy of lumbar vertebral body Hounsfield units (HUs) and pedicle HUs at predicting pedicle screw loosening. METHODS:The authors retrospectively assessed 143 patients with L3-5 instrumentation. The patients were classified into one of two groups based on the status of thei...

journal_title：Neurosurgical focus

authors： Xu F,Zou D,Li W,Sun Z,Jiang S,Zhou S,Li Z

更新日期：2020-08-01 00:00:00

abstract：:Vagus nerve stimulation (VNS) is a key tool in the treatment of patients with medically refractory epilepsy. Although the mechanism of action of VNS remains poorly understood, this modality is now the most widely used nonpharmacological treatment for drug-resistant epilepsy. The goal of this work is to review the hist...

journal_title：Neurosurgical focus

authors： Lulic D,Ahmadian A,Baaj AA,Benbadis SR,Vale FL

更新日期：2009-09-01 00:00:00

abstract：:During the past 20 years, the traditional supportive treatment for stroke has been radically transformed by advances in catheter technologies and a cohort of prominent randomized controlled trials that unequivocally demonstrated significant improvement in stroke outcomes with timely endovascular intervention. However,...

journal_title：Neurosurgical focus

authors： Vuong SM,Carroll CP,Tackla RD,Jeong WJ,Ringer AJ

更新日期：2017-04-01 00:00:00

abstract：:In this article the authors attempt to raise awareness of the pitfalls and controversial issues in nerve tumor surgery. In a case-guided format, examples of ambiguous findings, inappropriate tumor removal, repeated surgery, and nerve repairs are provided. The authors also discuss the need to establish a correct diagno...

journal_title：Neurosurgical focus

authors： Kretschmer T,Antoniadis G,Heinen C,Börm W,Scheller C,Richter HP,Koenig RW

更新日期：2007-06-15 00:00:00

abstract：:Cervical dural arteriovenous fistulas (dAVFs) are a rare cause of intracranial subarachnoid hemorrhage (SAH) but should be considered when other sources are not found. Subarachnoid hemorrhage caused by dAVF is thought to occur as a result of venous hypertension in most cases. The clinical presentation, acute onset of ...

journal_title：Neurosurgical focus

authors： Fassett DR,Rammos SK,Patel P,Parikh H,Couldwell WT

更新日期：2009-01-01 00:00:00

abstract：:The authors describe a surgical technique for the correction of symptomatic degenerative lumbar scoliosis. Using a single, unilateral, interbody cage placed on the concave side of the coronal deformity, combined with a dorsal decompression and instrumented posterolateral fusion, this technique has resulted in excellen...

journal_title：Neurosurgical focus

authors： Heary RF,Karimi RJ

更新日期：2010-03-01 00:00:00

abstract：:OBJECTIVE Minimally invasive posterior cervical decompression (miPCD) has been described in several case series with promising preliminary results. The object of the current study was to compare the clinical outcomes between patients undergoing miPCD with anterior cervical discectomy and instrumented fusion (ACDFi). M...

journal_title：Neurosurgical focus

authors： Abbas SF,Spurgas MP,Szewczyk BS,Yim B,Ata A,German JW

更新日期：2016-06-01 00:00:00

abstract：:Cerebral cavernous malformations (CCMs) are common vascular lesions of the CNS that may lead to seizures, focal neurological deficits, and fatal hemorrhagic stroke. Human genetic studies have identified 3 genes associated with CCM, and biochemical and molecular studies in mice have elucidated signaling pathways with i...

journal_title：Neurosurgical focus

authors： Krisht KM,Whitehead KJ,Niazi T,Couldwell WT

更新日期：2010-09-01 00:00:00

abstract：OBJECT:The aim of this study was to evaluate the effectiveness of an educational intervention on concussion knowledge within a sample of junior fourth-tier ice hockey players. METHODS:A prospective cohort study, called the Hockey Concussion Education Project, was conducted during 1 junior ice hockey regular season (20...

journal_title：Neurosurgical focus

authors： Echlin PS,Johnson AM,Riverin S,Tator CH,Cantu RC,Cusimano MD,Taunton JE,Upshur RE,Hall CR,Forwell LA,Skopelja EN

更新日期：2010-11-01 00:00:00

abstract：:OBJECTIVE In this study the authors describe the technical considerations and feasibility of transforaminal discectomy and foraminoplasty for the treatment of lumbar radiculopathy in patients who have herniated discs at the thoracolumbar junction. METHODS After institutional review board approval, charts from 3 consec...

journal_title：Neurosurgical focus

authors： Telfeian AE,Jasper GP,Oyelese AA,Gokaslan ZL

更新日期：2016-02-01 00:00:00

abstract：:The benefits of anterior interbody arthrodesis in deformity surgery are well known and include load sharing and increased fusion rates. A minimally invasive lateral transpsoas approach to the anterior lumbar spine is a promising alternative to traditional interbody techniques for the treatment of adult degenerative sc...

journal_title：Neurosurgical focus

authors： Amin BY,Mummaneni PV,Ibrahim T,Zouzias A,Uribe J

更新日期：2013-07-01 00:00:00

abstract：OBJECT:The aim of this study was to analyze the national health care burden of patients diagnosed with epilepsy in the US and to analyze any changes in the length of stay, mean charges, in-hospital deaths (mortality), and disposition at discharge. METHODS:A retrospective review of the Nationwide Inpatient Sample (NIS)...

journal_title：Neurosurgical focus

authors： Vivas AC,Baaj AA,Benbadis SR,Vale FL

更新日期：2012-03-01 00:00:00

abstract：:It is not uncommon for a severe traumatic brachial plexus injury to involve all 5 roots, resulting in a flail upper limb. In such cases, surgical reconstruction is often palliative, providing only rudimentary function. Nerve transfers are the mainstay of reconstructive strategies due to the predominance of root avulsi...

journal_title：Neurosurgical focus

authors： Bhatia A,Doshi P,Koul A,Shah V,Brown JM,Salama M

更新日期：2017-07-01 00:00:00

abstract：:Craniosynostosis is the premature fusion of one or more cranial sutures. When a cranial suture fuses prematurely, skull growth is altered and the head takes on a characteristic pathological shape determined by the suture(s) that fuses. Numerous treatment options have been proposed, but until recently there were no par...

journal_title：Neurosurgical focus

authors： Szpalski C,Weichman K,Sagebin F,Warren SM

更新日期：2011-08-01 00:00:00

abstract：:Since the earliest recorded history of medicine, physicians have been challenged by the difficulty in relieving the great pain experienced by individuals suffering from trigeminal neuralgia (TN). The nature of the pain and the events that incite it have been well described, but effective treatments with acceptable lev...

journal_title：Neurosurgical focus

authors： Cole CD,Liu JK,Apfelbaum RI

更新日期：2005-05-15 00:00:00

abstract：OBJECT:The direct transnasal transsphenoidal approach to the sellar region has become a widely adopted surgical procedure among neurosurgeons and ear, nose, and throat specialists. Nasal complications and their incidence have been investigated, but a systematic testing of olfactory disturbance has not previously been p...

journal_title：Neurosurgical focus

authors： Actor B,Sarnthein J,Prömmel P,Holzmann D,Bernays RL

更新日期：2010-10-01 00:00:00

abstract：OBJECT:Tumors of the lateral ventricle can be removed via two major approaches: the transcallosal or the transcortical route. The purpose of this study is to discuss the techniques and outcomes in transcortical surgery of tumors located in the lateral ventricle. METHODS:An experience with 29 consecutive lateral ventri...

journal_title：Neurosurgical focus

authors： Ellenbogen RG

更新日期：2001-06-15 00:00:00

abstract：:Electrodiagnostic testing in patients who have upper-extremity symptoms, which may include carpal tunnel syndrome (CTS), has been the gold standard for diagnosis for many years. Despite their value, these tests are underutilized. The authors examined the use patterns of electrodiagnostic testing at the University of V...

journal_title：Neurosurgical focus

authors： Phillips LH 2nd,Juel VC

更新日期：1997-07-15 00:00:00

abstract：:OBJECTIVE Many reports have successfully demonstrated that cervical disc arthroplasty (CDA) can preserve range of motion after 1- or 2-level discectomy. However, few studies have addressed the extent of changes in segmental mobility after CDA or their clinical correlations. METHODS Data from consecutive patients who u...

journal_title：Neurosurgical focus

authors： Chang HK,Chang CC,Tu TH,Wu JC,Huang WC,Fay LY,Chang PY,Wu CL,Cheng H

更新日期：2017-02-01 00:00:00

abstract：:The widespread use of fusion procedures in the management of spinal disorders has led investigators to explore the use of growth and differentiation factors in such procedures. As an adjuvant to allograft bone or as a replacement for harvested autograft, bone morphogenetic proteins (BMPs) appear to improve fusion rate...

journal_title：Neurosurgical focus

authors： Subach BR,Haid RW,Rodts GE,Kaiser MG

更新日期：2001-04-15 00:00:00