Role of the neurofibromatosis type 2 gene in the development of tumors of the nervous system.

abstract：:Genetic alterations in the cells of intradural spinal tumors can have a significant impact on the treatment options, counseling, and prognosis for patients. Although surgery is the primary therapy for most intradural tumors, radiochemothera-peutic modalities and targeted interventions play an ever-evolving role in tre...

journal_title：Neurosurgical focus

authors： Karsy M,Guan J,Sivakumar W,Neil JA,Schmidt MH,Mahan MA

更新日期：2015-08-01 00:00:00

abstract：OBJECT:Nonfunctioning pituitary adenomas comprise approximately 30% of all pituitary tumors. The purpose of this retrospective study was to evaluate the efficacy and role of gamma knife surgery (GKS) in the treatment of these lesions. METHODS:The authors conducted a review of cases in which GKS was performed at the Un...

journal_title：Neurosurgical focus

authors： Sheehan JP,Kondziolka D,Flickinger J,Lunsford LD

更新日期：2003-05-15 00:00:00

abstract：:Traumatic intracranial aneurysms are rare, occurring in fewer than 1% of patients with cerebral aneurysms. They can occur following blunt or penetrating head trauma and are more common in the pediatric population. Traumatic aneurysms can be categorized histologically as true, false, or mixed, with false aneurysms bein...

journal_title：Neurosurgical focus

authors： Larson PS,Reisner A,Morassutti DJ,Abdulhadi B,Harpring JE

更新日期：2000-01-15 00:00:00

abstract：OBJECT:The purpose of this study was to elucidate the anatomy of the trigeminal nerve (cranial nerve [CN] V), Meckel cave (MC), and lateral wall of the cavernous sinus (CS). METHODS:Ten fresh cadaver heads (20 sides) and 2 middle fossa embalmed specimens were removed, decalcified, sectioned, stained, and studied micro...

journal_title：Neurosurgical focus

authors： Janjua RM,Al-Mefty O,Densler DW,Shields CB

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The authors aimed to compare the efficacy of lumbar vertebral body Hounsfield units (HUs) and pedicle HUs at predicting pedicle screw loosening. METHODS:The authors retrospectively assessed 143 patients with L3-5 instrumentation. The patients were classified into one of two groups based on the status of thei...

journal_title：Neurosurgical focus

authors： Xu F,Zou D,Li W,Sun Z,Jiang S,Zhou S,Li Z

更新日期：2020-08-01 00:00:00

abstract：OBJECT:Chordomas have a high propensity for local recurrence and progression, as well as for systemic and cerebrospinal fluid metastasis. The authors identified and analyzed a series of patients with chordomas, focusing on an underrecognized entity--surgical seeding. METHODS:In a retrospective analysis of 82 patients ...

journal_title：Neurosurgical focus

authors： Arnautović KI,Al-Mefty O

更新日期：2001-03-15 00:00:00

abstract：:From February 4 to 11, 1945, President Franklin D. Roosevelt of the United States, Soviet Union Premier Joseph Stalin, and British Prime Minister Winston Churchill met near Yalta in Crimea to discuss how post-World War II (WWII) Europe should be organized. Within 2 decades of this conference, all 3 men had died. Presi...

journal_title：Neurosurgical focus

authors： Ali R,Connolly ID,Li A,Choudhri OA,Pendharkar AV,Steinberg GK

更新日期：2016-07-01 00:00:00

abstract：:A 29-year-old woman is diagnosed with a large broad-base right ophthalmic artery aneurysm. Despite an intact visual field, she complained of mild right visual blurriness. Between endovascular and surgical treatments, surgery was favored due to her young age. It was decided to perform the surgery with simultaneous endo...

journal_title：Neurosurgical focus

authors： Dehdashti AR

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The microvascular anatomy of spinal perimedullary arteriovenous fistulas (AVFs) is more complicated than that of dural AVFs, and occlusion rates of AVF after open microsurgery or endovascular embolization are lower in patients with perimedullary AVFs (29%-70%) than they are in those with dural AVF (97%-98%). ...

journal_title：Neurosurgical focus

authors： Takai K,Kurita H,Hara T,Kawai K,Taniguchi M

更新日期：2016-03-01 00:00:00

abstract：:Degenerative lumbar spinal stenosis is a common condition affecting middle-aged and elderly people. Significant controversy exists concerning the appropriate indications for fusion following decompressive surgery. The purpose of this report is to compare the clinical outcomes of patients who were and were not treated ...

journal_title：Neurosurgical focus

authors： Fox MW,Onofrio BM

更新日期：1997-08-15 00:00:00

abstract：:Deep brain stimulation (DBS) has been reported to have beneficial effects in severe, treatment-refractory cases of obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). In this report, the authors present the first case in which DBS was used to treat the neuropsychiatric symptoms of Kleefstra syndrome, a rar...

journal_title：Neurosurgical focus

authors： Segar DJ,Chodakiewitz YG,Torabi R,Cosgrove GR

更新日期：2015-06-01 00:00:00

abstract：:Spina bifida is the most common nonchromosomal birth defect, resulting in permanent disability of multiple organ systems, yet compatible with long-term survival. Important advances across various disciplines have now improved survival among the spina bifida population. Although the majority of individuals living with ...

journal_title：Neurosurgical focus

authors： Patel SK,Staarmann B,Heilman A,Mains A,Woodward J,Bierbrauer KS

更新日期：2019-10-01 00:00:00

abstract：:OBJECTIVE Stereoelectroencephalography (sEEG) and MR-guided laser interstitial thermal therapy (MRgLITT) have both emerged as minimally invasive alternatives to open surgery for the localization and treatment of medically refractory lesional epilepsy. Although some data are available about the use of these procedures ...

journal_title：Neurosurgical focus

authors： Cobourn K,Fayed I,Keating RF,Oluigbo CO

更新日期：2018-09-01 00:00:00

abstract：:Intensive care of the patient with traumatic brain injury centers on control of intracranial pressure and cerebral perfusion pressure (CPP). The optimal CPP by definition delivers an adequate supply of blood and oxygen to meet the metabolic demands of brain tissue. A great deal of controversy exists regarding the opti...

journal_title：Neurosurgical focus

authors： Vespa P

更新日期：2003-12-15 00:00:00

abstract：:The histological appearance of a meningioma is an important predictor of tumor behavior and is frequently a factor in decisions concerning therapy. The relationship between histological features and prognosis is formalized in grading schemes such as those published by the World Health Organization (WHO), most recently...

journal_title：Neurosurgical focus

authors： Commins DL,Atkinson RD,Burnett ME

更新日期：2007-01-01 00:00:00

abstract：:Stereotactic radiosurgery is commonly used for selected patients with benign cranial base tumors. The goal of radiosurgery is cessation of tumor growth and preservation of neurological function. Over the last 2 decades, the technique of radiosurgery has evolved due to improved imaging, better radiosurgical devices and...

journal_title：Neurosurgical focus

authors： Kondziolka D,Flickinger JC,Lunsford LD

更新日期：2008-01-01 00:00:00

abstract：:The study of carotid artery occlusive disease interventions can be divided clinically into the treatment of asymptomatic and symptomatic diseases. Clinical trials that have studied or are currently studying asymptomatic disease include: the Carotid Artery Stenosis with Asymptomatic Narrowing Operation Versus Aspirin s...

journal_title：Neurosurgical focus

authors： Brennan JJ,Loftus CM

更新日期：1998-12-15 00:00:00

abstract：:With the aid of a computer model, this investigation describes the relationship between mean arterial pressure (MAP) reduction and its effect on total arteriovenous malformation (AVM) shunt flow, feeding artery velocities, and cerebral blood flow in hypotensive, structurally normal vascular beds adjacent to the AVM ni...

journal_title：Neurosurgical focus

authors： Gao E,Young WL,Pile-Spellman J,Ornstein E,Ma Q

更新日期：1997-06-15 00:00:00

abstract：:Sacral fractures are uncommon lesions and most often the result of high-energy trauma. Depending on the fracture location, neurological injury may be present in over 50% of cases. In this article, the authors conducted a comprehensive literature review on the epidemiology of sacral fractures, relevant anatomy of the s...

journal_title：Neurosurgical focus

authors： Bydon M,Fredrickson V,De la Garza-Ramos R,Li Y,Lehman RA Jr,Trost GR,Gokaslan ZL

更新日期：2014-01-01 00:00:00

abstract：OBJECT:Anterior cervical discectomy (ACD) is an effective and safe treatment for nerve root or spinal cord compression caused by disc herniation or spondylosis. Cervical interbody fusion allows preservation of the physiological lordosis and stability of the cervical spine. Based on data reported in the literature, fusi...

journal_title：Neurosurgical focus

authors： Assietti R,Beretta F,Arienta C

更新日期：2002-01-15 00:00:00

abstract：:Lumbosacral interbody fusion may be indicated to treat degenerative disc disease at L5-S1, instability or spondylolisthesis at that level, and severe neural foraminal stenosis resulting from loss of disc space height. In addition, L5-S1 interbody fusion may provide anterior support to a long posterior fusion construct...

journal_title：Neurosurgical focus

authors： Issack PS,Kotwal SY,Boachie-Adjei O

更新日期：2014-05-01 00:00:00

abstract：:OBJECTIVE Despite the advances in skull base techniques, large petroclival meningiomas (PCMs) still pose a challenge to neurosurgeons. The authors' objective of this study was to describe a pretemporal trans-Meckel's cave transtentorial approach for large PCMs and to report the surgical outcomes. METHODS From 2014 to ...

journal_title：Neurosurgical focus

authors： Liao CH,Wang JT,Lin CF,Chen SC,Lin CJ,Hsu SPC,Chen MH

更新日期：2018-04-01 00:00:00

abstract：:OBJECTIVEPapers from 2002 to 2017 have highlighted consistent unique socioeconomic challenges and opportunities facing military neurosurgeons. Here, the authors focus on the reserve military neurosurgeon who carries the dual mission of both civilian and military responsibilities.METHODSSurvey solicitation of current a...

journal_title：Neurosurgical focus

authors： Menger R,Mundell BF,Robbins JW,Letarte P,Bell R,in conjunction with Council of State Neurosurgical Societies and AANS\/CNS Joint Committee of Military Neurosurgeons.

更新日期：2018-12-01 00:00:00

abstract：:OBJECTIVE The performance of surgery for spinal metastases is rapidly increasing. Different surgical procedures, ranging from stabilization alone to stabilization combined with corpectomy, are thereby performed for various indications. Little is known about the impact of these different procedures on patient quality o...

journal_title：Neurosurgical focus

authors： de Ruiter GC,Nogarede CO,Wolfs JF,Arts MP

更新日期：2017-01-01 00:00:00

abstract：OBJECT:It is hypothesized that minimally invasive surgical techniques lead to fewer complications than open surgery for adult spinal deformity (ASD). The goal of this study was to analyze matched patient cohorts in an attempt to isolate the impact of approach on adverse events. METHODS:Two multicenter databases querie...

journal_title：Neurosurgical focus

authors： Uribe JS,Deukmedjian AR,Mummaneni PV,Fu KM,Mundis GM Jr,Okonkwo DO,Kanter AS,Eastlack R,Wang MY,Anand N,Fessler RG,La Marca F,Park P,Lafage V,Deviren V,Bess S,Shaffrey CI,International Spine Study Group.

更新日期：2014-05-01 00:00:00

abstract：:In this article, the author provides a brief description of the role of hypoxia in the tumorigenesis of gliomas and suggests potential ways of exploiting this role to design treatment modalities. Tumor hypoxia predicts the likelihood of metastases, tumor recurrence, resistance to chemotherapy and radiation therapy, in...

journal_title：Neurosurgical focus

authors： Jensen RL

更新日期：2006-04-15 00:00:00

abstract：:High-flow microinfusion is a novel technique for delivery of compounds directly into the brain parenchyma, bypassing the blood-brain barrier. The feasibility of this technique has been demonstrated with low-molecular-weight compounds, macromolecular dyes, and proteins. Delivery of antisense oligonucleotides into the b...

journal_title：Neurosurgical focus

authors： Broaddus WC,Prabhu SS,Gillies GT,Neal J,Conrad WS,Chen ZJ,Fillmore H,Young HF

更新日期：1997-11-15 00:00:00

abstract：:The Quality Outcomes Database (QOD), formerly known as the National Neurosurgery Quality Outcomes Database (N2QOD), was established by the NeuroPoint Alliance (NPA) in collaboration with relevant national stakeholders and experts. The overarching goal of this project was to develop a centralized, nationally coordinate...

journal_title：Neurosurgical focus

authors： Asher AL,Knightly J,Mummaneni PV,Alvi MA,McGirt MJ,Yolcu YU,Chan AK,Glassman SD,Foley KT,Slotkin JR,Potts EA,Shaffrey ME,Shaffrey CI,Haid RW,Fu KM,Wang MY,Park P,Bisson EF,Harbaugh RE,Bydon M

更新日期：2020-05-01 00:00:00

abstract：:Cerebral venous sinus thrombosis (CVST) is characterized by formation of widespread thrombus within the cerebral venous sinus system. CVST can cause venous hypertension, venous infarcts, hemorrhage and seizures. It is managed in most cases with systemic anticoagulation through the use of heparin to resolve the thrombu...

journal_title：Neurosurgical focus

authors： Choudhri O,Feroze A,Marks MP,Do HM

更新日期：2014-07-01 00:00:00

abstract：Objective:Treatment advances have resulted in improved survival for many cancer types, and this, in turn, has led to an increased incidence of metastatic disease, specifically to the vertebral column. Surgical decompression and stabilization prior to radiation therapy have been shown to improve functional outcomes, but...

journal_title：Neurosurgical focus

authors： Ravindra VM,Brock A,Awad AW,Kalra R,Schmidt MH

更新日期：2016-08-01 00:00:00