What is the optimal threshold for cerebral perfusion pressure following traumatic brain injury?

Abstract:

:Intensive care of the patient with traumatic brain injury centers on control of intracranial pressure and cerebral perfusion pressure (CPP). The optimal CPP by definition delivers an adequate supply of blood and oxygen to meet the metabolic demands of brain tissue. A great deal of controversy exists regarding the optimal CPP value, with disparate studies providing conflicting evidence for the use of supraphysiological CPP values. No study that accurately assesses the efficacy of normal CPP compared with elevated CPP has been performed, but several studies demonstrate that a CPP threshold exists on an individual basis for patients with TBI. The use of brain monitors of cerebral metabolism and oxygen supply may assist the clinician in the selection of the optimal CPP for an individual patient.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Vespa P

doi

10.3171/foc.2003.15.6.4

subject

Has Abstract

pub_date

2003-12-15 00:00:00

pages

E4

issue

6

issn

1092-0684

pii

150604

journal_volume

15

pub_type

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