Craniofacial reconstruction with a fast resorbing polymer: a 6- to 12-month clinical follow-up review.

Abstract:

OBJECT:Resorbable polymer implants have become a compelling option in the treatment of acquired and congenital craniofacial deformities. In particular, the resorbable polylactide and polyglycolide polymers have demonstrated excellent safety profiles in multiple in vitro, animal, and clinical studies and are currently being used in a wide variety of craniofacial applications. In pediatric craniofacial reconstruction a desirable attribute of fixation is early resorption, which may limit the duration of any effect on cranial growth. In this paper the authors discuss the biomaterial properties of a fast resorbing polymer (FRP) and the clinical results in a series of patients who participated in a 6- to 12-month study. METHODS:The authors performed craniofacial reconstruction by using FRP implants in 29 patients beginning in August 2002. All patients experienced maintenance of stable bone fixation followed by bone healing. Cosmetic results were rated satisfactory or excellent, except for one unsatisfactory cosmetic result caused by disease progression. CONCLUSIONS:Results of this study support the effectiveness of an FRP implant in a variety of craniofacial surgical procedures including craniosynostoses, fibrous dysplasia, cranial defects, and encephaloceles.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Cohen SR,Holmes RE,Meltzer HS,Levy ML,Beckett MZ

doi

10.3171/foc.2004.16.3.13

subject

Has Abstract

pub_date

2004-03-15 00:00:00

pages

E12

issue

3

issn

1092-0684

pii

160312

journal_volume

16

pub_type

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