Cerebral cavernous malformations and epilepsy.

Abstract:

:Seizures and epilepsy are frequent clinical manifestations of cerebral cavernous malformations (CCMs) and represent the most common symptomatic presentation of supratentorial lesions. Clinicians often diagnose CCMs in patients after a first seizure, or in some cases after obtaining neuroimaging studies in patients suffering from chronic epilepsy previously thought to be idiopathic. In some cases, the lesion is clinically significant solely because of its epileptogenicity, but in others there may be concern about potential hemorrhage or focal neurological deficits from a similar lesion. The authors present current pathophysiological concepts related to epilepsy associated with CCMs. They discuss the spectrum of seizure disorders associated with these lesions and review the natural history, prognosis, and options for therapeutic intervention.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Awad I,Jabbour P

doi

10.3171/foc.2006.21.1.8

subject

Has Abstract

pub_date

2006-07-15 00:00:00

pages

e7

issue

1

issn

1092-0684

pii

210107

journal_volume

21

pub_type

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