What neurosurgeons should do to succeed in tomorrow's scientific and socioeconomic environment.

abstract：:Lumbosacral interbody fusion may be indicated to treat degenerative disc disease at L5-S1, instability or spondylolisthesis at that level, and severe neural foraminal stenosis resulting from loss of disc space height. In addition, L5-S1 interbody fusion may provide anterior support to a long posterior fusion construct...

journal_title：Neurosurgical focus

authors： Issack PS,Kotwal SY,Boachie-Adjei O

更新日期：2014-05-01 00:00:00

abstract：OBJECT:Mild traumatic brain injury (MTBI), often referred to as concussion when it occurs in sports, produces persistent cognitive problems in at least 15% of patients. Unfortunately, conventional neuropsychological tests usually yield results within normal limits in this population. The main objective of this event-re...

journal_title：Neurosurgical focus

authors： Gosselin N,Bottari C,Chen JK,Huntgeburth SC,De Beaumont L,Petrides M,Cheung B,Ptito A

更新日期：2012-12-01 00:00:00

abstract：:Spina bifida is the most common nonchromosomal birth defect, resulting in permanent disability of multiple organ systems, yet compatible with long-term survival. Important advances across various disciplines have now improved survival among the spina bifida population. Although the majority of individuals living with ...

journal_title：Neurosurgical focus

authors： Patel SK,Staarmann B,Heilman A,Mains A,Woodward J,Bierbrauer KS

更新日期：2019-10-01 00:00:00

abstract：:OBJECT Bevacizumab (Avastin), an antibody to vascular endothelial growth factor (VEGF), alone or in combination with irinotecan (Camptosar [CPT-11]), is a promising treatment for recurrent glioblastoma. However, the intravenous (IV) administration of bevacizumab produces a number of systemic side effects, and the incr...

journal_title：Neurosurgical focus

authors： Wang W,Sivakumar W,Torres S,Jhaveri N,Vaikari VP,Gong A,Howard A,Golden EB,Louie SG,Schönthal AH,Hofman FM,Chen TC

更新日期：2015-03-01 00:00:00

abstract：:Cerebral venous sinus thrombosis (CVST) is characterized by formation of widespread thrombus within the cerebral venous sinus system. CVST can cause venous hypertension, venous infarcts, hemorrhage and seizures. It is managed in most cases with systemic anticoagulation through the use of heparin to resolve the thrombu...

journal_title：Neurosurgical focus

authors： Choudhri O,Feroze A,Marks MP,Do HM

更新日期：2014-07-01 00:00:00

abstract：:Anterior screw fixation of Type II odontoid fractures provides immediate stabilization of the cervical spine while preserving C1-2 motion. This technique has a high fusion rate, but can be technically challenging. The authors identify key points that should be taken into account to maximize the chance for a favorable ...

journal_title：Neurosurgical focus

authors： Mazur MD,Mumert ML,Bisson EF,Schmidt MH

更新日期：2011-10-01 00:00:00

abstract：:Trigeminal neuropathic pain is a syndrome of severe, constant facial pain related to disease of or injury to the trigeminal nerve or ganglion. Causes of this type of pain can include injury from sinus or dental surgery, skull and/or facial trauma, or intentional destruction for therapeutic reasons (deafferentation) as...

journal_title：Neurosurgical focus

authors： Henderson JM,Lad SP

更新日期：2006-12-15 00:00:00

abstract：:The authors present a brief and selective history of surgery for peripheral nerve tumors to illustrate how the current understanding of the nature of disease influences the choice of surgical intervention. There was very little understanding of the anatomy and function of peripheral nerves in ancient times; consequent...

journal_title：Neurosurgical focus

authors： Powers CJ,Friedman AH

更新日期：2007-06-15 00:00:00

abstract：:OBJECT The objective of this study was to provide a technique that could be used in the preoperative period to facilitate the surgical exploration of peripheral nerve pathology. METHODS The authors describe a technique in which 1) ultrasonography is used in the immediate preoperative period to identify target peripher...

journal_title：Neurosurgical focus

authors： Osorio JA,Breshears JD,Arnaout O,Simon NG,Hastings-Robinson AM,Aleshi P,Kliot M

更新日期：2015-09-01 00:00:00

abstract：OBJECT:Diagnosis of cervical spinal injury (CSI) is an essential aspect of the trauma evaluation. This task is especially difficult in patients who are not clinically able to be evaluated (unevaluable) because of distracting painful injuries, intoxication, or concomitant head injury. For this population, the appropriat...

journal_title：Neurosurgical focus

authors： Milby AH,Halpern CH,Guo W,Stein SC

更新日期：2008-01-01 00:00:00

abstract：:Economic evaluations provide a decision-making framework in which outcomes (benefits) and costs are assessed for various alternative options. Although the interest in complete and partial economic evaluations has increased over the past 2 decades, the quality of studies has been marginal due to methodological challeng...

journal_title：Neurosurgical focus

authors： McLaughlin N,Ong MK,Tabbush V,Hagigi F,Martin NA

更新日期：2014-11-01 00:00:00

abstract：:Healthcare spending has become a grave concern to national budgets worldwide, and to a greater extent in low-income countries. Brain tumors are a serious disease that affects a significant percentage of the population, and thus proper allocation of healthcare provisions for these patients to achieve acceptable outcome...

journal_title：Neurosurgical focus

authors： Helal AE,Abouzahra H,Fayed AA,Rayan T,Abbassy M

更新日期：2018-10-01 00:00:00

abstract：:Advances in medical and surgical treatments in the last few decades have resulted in quantum leaps in the overall survival of patients with malignant disease outside the central nervous system, whereas survival of patients with malignant gliomas (World Health Organization Grades III and IV) has remained essentially un...

journal_title：Neurosurgical focus

authors： Rainov NG,Söling A,Heidecke V

更新日期：2006-04-15 00:00:00

abstract：:OBJECTIVE In this study the authors describe the technical considerations and feasibility of transforaminal discectomy and foraminoplasty for the treatment of lumbar radiculopathy in patients who have herniated discs at the thoracolumbar junction. METHODS After institutional review board approval, charts from 3 consec...

journal_title：Neurosurgical focus

authors： Telfeian AE,Jasper GP,Oyelese AA,Gokaslan ZL

更新日期：2016-02-01 00:00:00

abstract：:The contemporary management of projectile head injuries owes much to the lessons neurosurgeons have distilled from their experiences in war. Through early investigation and an increasingly detailed account of wartime clinical experience, neurosurgeons--including the field's early giants--began to gain a greater unders...

journal_title：Neurosurgical focus

authors： Agarwalla PK,Dunn GP,Laws ER

更新日期：2010-05-01 00:00:00

abstract：OBJECT:Hypothalamic hamartomas (HHs) are devastating lesions causing refractory epilepsy, rage attacks, social ineptitude, and precocious puberty. Microsurgical and/or endoscopic resection offers an excellent risk/benefit profile for cure or improvement of epilepsy. METHODS:The authors reviewed a prospective database ...

journal_title：Neurosurgical focus

authors： Wait SD,Abla AA,Killory BD,Nakaji P,Rekate HL

更新日期：2011-02-01 00:00:00

abstract：OBJECT:A more comprehensive understanding of the epigenetic abnormalities associated with meningioma tumorigenesis, growth, and invasion may provide useful targets for molecular classification and development of targeted therapies for meningiomas. METHODS:The authors performed a review of the current literature to ide...

journal_title：Neurosurgical focus

authors： He S,Pham MH,Pease M,Zada G,Giannotta SL,Wang K,Mack WJ

更新日期：2013-12-01 00:00:00

abstract：:Cysticercosis is the most common parasitic infection of the central nervous system. It infrequently affects the spine, but when it does, it can present with symptoms similar to other more common spinal diseases. The authors present a case of isolated intramedullary cysticercosis of the cervical spine and review the li...

journal_title：Neurosurgical focus

authors： Sheehan JP,Sheehan J,Lopes MB,Jane JA Sr

更新日期：2002-06-15 00:00:00

abstract：:Stereotactic radiosurgery is commonly used for selected patients with benign cranial base tumors. The goal of radiosurgery is cessation of tumor growth and preservation of neurological function. Over the last 2 decades, the technique of radiosurgery has evolved due to improved imaging, better radiosurgical devices and...

journal_title：Neurosurgical focus

authors： Kondziolka D,Flickinger JC,Lunsford LD

更新日期：2008-01-01 00:00:00

abstract：:Cellular replacement therapy attempts to improve functioning of the diseased human central nervous system (CNS). In this second installment of a 2-part review, the authors discuss the major challenges to the translation of in vitro and animal studies of neural stem cell (NSC) therapy in the clinical setting. This anal...

journal_title：Neurosurgical focus

authors： Selden NR,Guillaume DJ,Steiner RD,Huhn SL

更新日期：2008-01-01 00:00:00

abstract：OBJECT:Coil embolization of aneurysms has been shown to be as safe and effective as surgical clip ligation, but has a higher recurrence rate. Advances in coil technology aim to reduce aneurysm recurrence by coating the devices with biological substances. An example of this is MicroVention's HydroCoil, which is a platin...

journal_title：Neurosurgical focus

authors： Deshaies EM,Bagla S,Agner C,Boulos AS

更新日期：2005-02-15 00:00:00

abstract：:OBJECTIVE The authors describe their results using an endoscope as an adjunct to microsurgical resection of inferior vestibular schwannomas (VSs) with extension into the fundus of the internal auditory canal below the transverse crest. METHODS All patients who had undergone middle fossa craniotomy for VSs performed by...

journal_title：Neurosurgical focus

authors： Master AN,Roberts DS,Wilkinson EP,Slattery WH,Lekovic GP

更新日期：2018-03-01 00:00:00

abstract：OBJECT:The authors present a series of 4 patients with rare facial nerve tumors. The relevant literature is reviewed and is discussed regarding diagnostic features, the role of operative management, and surgical approach. METHODS:A retrospective chart review was conducted for patients with tumors of the facial nerve t...

journal_title：Neurosurgical focus

authors： Ross L,Drazin D,Eboli P,Lekovic GP

更新日期：2013-03-01 00:00:00

abstract：:Intravenous and intraarterial recombinant tissue plasminogen activator remains underutilized in the treatment of acute ischemic stroke, largely due to strict adherence to the concept of the therapeutic time window for administration. Recent efforts to expand the number of patients eligible for thrombolysis have been m...

journal_title：Neurosurgical focus

authors： Amenta PS,Ali MS,Dumont AS,Gonzalez LF,Tjoumakaris SI,Hasan D,Rosenwasser RH,Jabbour P

更新日期：2011-06-01 00:00:00

abstract：:Recent technical advances have revolutionized the fields of surgical endoscopy, laparoscopy, thoracoscopy, and microsurgical spinal endoscopy. The authors discuss the rich history and recent evolution of these techniques. Thoracoscopy had been widely used for the treatment of pleural conditions associated with tubercu...

journal_title：Neurosurgical focus

authors： Das K,Rothberg M

更新日期：2000-10-15 00:00:00

abstract：OBJECT:Nonfunctioning pituitary adenomas comprise approximately 30% of all pituitary tumors. The purpose of this retrospective study was to evaluate the efficacy and role of gamma knife surgery (GKS) in the treatment of these lesions. METHODS:The authors conducted a review of cases in which GKS was performed at the Un...

journal_title：Neurosurgical focus

authors： Sheehan JP,Kondziolka D,Flickinger J,Lunsford LD

更新日期：2003-05-15 00:00:00

abstract：OBJECT:The relatively stationary anatomy of the intracranial compartment has allowed the development of stereotactic radiosurgery as an effective treatment option for many intracranial lesions. Difficulty in accurately tracking extracranial targets has limited its development in the treatment of these lesions. The abil...

journal_title：Neurosurgical focus

authors： Ryken TC,Meeks SL,Traynelis V,Haller J,Bouchet LG,Bova FJ,Pennington EC,Buatti JM

更新日期：2001-12-15 00:00:00

abstract：:Tentorial dural arteriovenous fistulae (TDAVFs) are complex lesions with the arteriovenous fistula located between the leaves of the tentorium cerebelli. While a large portion of dural arteriovenous fistulae are treated endovascularly, TDAVF may require additional microsurgical treatment given their high risk of hemor...

journal_title：Neurosurgical focus

authors： Choudhri O,Steinberg GK

更新日期：2016-01-01 00:00:00

abstract：OBJECT:Simultaneous endoscopic third ventriculostomy (ETV) and tumor biopsy is a widely accepted therapeutic and diagnostic procedure for patients with noncommunicating hydrocephalus secondary to a pineal region tumor. Multiple approaches have been advocated, including the use of a steerable fiberoptic or rigid lens en...

journal_title：Neurosurgical focus

authors： Morgenstern PF,Osbun N,Schwartz TH,Greenfield JP,Tsiouris AJ,Souweidane MM

更新日期：2011-04-01 00:00:00

abstract：:Our understanding of glioblastoma multiforme (GBM), the most common form of primary brain cancer, has been significantly advanced by recent efforts to characterize the cancer genome using unbiased high-throughput sequencing analyses. While these studies have documented hundreds of mutations, gene copy alterations, and...

journal_title：Neurosurgical focus

authors： Kahle KT,Kozono D,Ng K,Hsieh G,Zinn PO,Nitta M,Chen CC

更新日期：2010-01-01 00:00:00