Functional genomics to explore cancer cell vulnerabilities.

abstract：:OBJECTIVE The treatment of cervical spinal metastases represents a controversial issue regarding the type, extent, and invasiveness of interventions. In the lumbar and thoracic spine, kypho- and vertebroplasties have been established as minimally invasive procedures for patients with metastases to the vertebral bodies...

journal_title：Neurosurgical focus

authors： Stangenberg M,Viezens L,Eicker SO,Mohme M,Mende KC,Dreimann M

更新日期：2017-08-01 00:00:00

abstract：OBJECT:Parallel advancements in image guidance technology and minimal access techniques continue to push the frontiers of minimally invasive spine surgery (MISS). While traditional intraoperative imaging remains widely used, newer platforms, such as 3D-fluoroscopy, cone-beam CT, and intraoperative CT/MRI, have enabled ...

journal_title：Neurosurgical focus

authors： Moses ZB,Mayer RR,Strickland BA,Kretzer RM,Wolinsky JP,Gokaslan ZL,Baaj AA

更新日期：2013-08-01 00:00:00

abstract：OBJECT:The relatively stationary anatomy of the intracranial compartment has allowed the development of stereotactic radiosurgery as an effective treatment option for many intracranial lesions. Difficulty in accurately tracking extracranial targets has limited its development in the treatment of these lesions. The abil...

journal_title：Neurosurgical focus

authors： Ryken TC,Meeks SL,Traynelis V,Haller J,Bouchet LG,Bova FJ,Pennington EC,Buatti JM

更新日期：2001-12-15 00:00:00

abstract：:Chronic subarachnoid hemorrhage may cause deposition of hemosiderin on the leptomeninges and subpial layers of the neuraxis, leading to superficial siderosis (SS). The symptoms and signs of SS are progressive and fatal. Exploration of potential sites responsible for intrathecal bleeding and subsequent hemosiderin depo...

journal_title：Neurosurgical focus

authors： Cohen-Gadol AA,Krauss WE,Spinner RJ

更新日期：2004-05-15 00:00:00

abstract：OBJECT:Hemangiopericytomas represent a small subset of meningeal tumors. Despite their relatively uncommon nature, they are aggressive tumors known for recurrence. Resection is the standard treatment in most, although regrowth and metastases are common even after resection. The authors evaluate the role of stereotactic...

journal_title：Neurosurgical focus

authors： Chang SD,Sakamoto GT

更新日期：2003-05-15 00:00:00

abstract：OBJECT:Mild traumatic brain injury (MTBI), often referred to as concussion when it occurs in sports, produces persistent cognitive problems in at least 15% of patients. Unfortunately, conventional neuropsychological tests usually yield results within normal limits in this population. The main objective of this event-re...

journal_title：Neurosurgical focus

authors： Gosselin N,Bottari C,Chen JK,Huntgeburth SC,De Beaumont L,Petrides M,Cheung B,Ptito A

更新日期：2012-12-01 00:00:00

abstract：OBJECT:An experimental study was performed to determine the biomechanical end-mounting configurations that replicate in vivo physiological motion of the cervical spine in a multiple-level human cadaveric model. The vertebral motion response for the modified testing protocol was compared to in vivo motion data and tradi...

journal_title：Neurosurgical focus

authors： DiAngelo DJ,Foley KT

更新日期：2004-09-15 00:00:00

abstract：:Moyamoya disease is an uncommon cerebrovascular condition characterized by progressive stenosis of the bilateral internal carotid arteries with compensatory formation of an abnormal network of perforating blood vessels providing collateral circulation. The etiology and pathogenesis of moyamoya disease remain unclear. ...

journal_title：Neurosurgical focus

authors： Achrol AS,Guzman R,Lee M,Steinberg GK

更新日期：2009-04-01 00:00:00

abstract：:Spine surgery has been disproportionately impacted by medical liability and malpractice litigation, with the majority of claims and payouts related to procedural error. One common area for the potential avoidance of malpractice claims and subsequent payouts involves misplaced pedicle and/or lateral mass instrumentatio...

journal_title：Neurosurgical focus

authors： Sankey EW,Mehta VA,Wang TY,Than TT,Goodwin CR,Karikari IO,Shaffrey CI,Abd-El-Barr MM,Than KD

更新日期：2020-11-01 00:00:00

abstract：OBJECT:Minimally invasive lumbar discectomy is a refinement of the standard open microsurgical discectomy technique. Proponents of the minimally invasive technique suggest that it improves patient outcome, shortens hospital stay, and decreases hospital costs. Despite these claims there is little support in the literatu...

journal_title：Neurosurgical focus

authors： German JW,Adamo MA,Hoppenot RG,Blossom JH,Nagle HA

更新日期：2008-01-01 00:00:00

abstract：OBJECT:Jugular foramen tumors are rare skull base lesions that present diagnostic and complex management problems. The purpose of this study was to evaluate a series of patients with jugular foramen tumors who were surgically treated in the past 16 years, and to analyze the surgical technique, complications, and outcom...

journal_title：Neurosurgical focus

authors： Ramina R,Maniglia JJ,Fernandes YB,Paschoal JR,Pfeilsticker LN,Neto MC,Borges G

更新日期：2004-08-15 00:00:00

abstract：:OBJECTIVEFew studies have been published specifically examining intravenous drug abuse (IVDA)-associated spinal epidural abscesses (SEAs), an unfortunate sequela of the opioid crisis in the United States. Here, the authors examined a series of patients with IVDA-associated SEAs in order to shed light on this challengi...

journal_title：Neurosurgical focus

authors： DiGiorgio AM,Stein R,Morrow KD,Robichaux JM,Crutcher CL,Tender GC

更新日期：2019-01-01 00:00:00

abstract：:Since the development of the WHO Safe Surgery Saves Lives initiative and Surgical Safety Checklist, numerous hospitals across the globe have adopted the use of a surgical checklist. The UCLA Health System developed its first extended Surgical Safety Checklist in 2008. Authors of the present paper describe how the time...

journal_title：Neurosurgical focus

authors： McLaughlin N,Winograd D,Chung HR,Van de Wiele B,Martin NA

更新日期：2012-11-01 00:00:00

abstract：:OBJECTIVE Despite the advances in skull base techniques, large petroclival meningiomas (PCMs) still pose a challenge to neurosurgeons. The authors' objective of this study was to describe a pretemporal trans-Meckel's cave transtentorial approach for large PCMs and to report the surgical outcomes. METHODS From 2014 to ...

journal_title：Neurosurgical focus

authors： Liao CH,Wang JT,Lin CF,Chen SC,Lin CJ,Hsu SPC,Chen MH

更新日期：2018-04-01 00:00:00

abstract：:Lumbosacral interbody fusion may be indicated to treat degenerative disc disease at L5-S1, instability or spondylolisthesis at that level, and severe neural foraminal stenosis resulting from loss of disc space height. In addition, L5-S1 interbody fusion may provide anterior support to a long posterior fusion construct...

journal_title：Neurosurgical focus

authors： Issack PS,Kotwal SY,Boachie-Adjei O

更新日期：2014-05-01 00:00:00

abstract：OBJECT:The object of this study was to compare the effects and complications of manual and computer-aided shaping of titanium meshes for repairing large frontotemporoparietal skull defects following traumatic brain injury. METHODS:From March 2005 to June 2011, 161 patients with frontotemporoparietal skull defects were...

journal_title：Neurosurgical focus

authors： Luo J,Liu B,Xie Z,Ding S,Zhuang Z,Lin L,Guo Y,Chen H,Yu X

更新日期：2012-07-01 00:00:00

abstract：:Spine surgery carries an inherent risk of damage to critical neural structures. Intraoperative neurophysiological monitoring (IONM) is frequently used to improve the safety of spine surgery by providing real-time assessment of neural structures at risk. Evidence-based guidelines for safe and efficacious use of IONM ar...

journal_title：Neurosurgical focus

authors： Lall RR,Lall RR,Hauptman JS,Munoz C,Cybulski GR,Koski T,Ganju A,Fessler RG,Smith ZA

更新日期：2012-11-01 00:00:00

abstract：OBJECT:Positional plagiocephaly (PP) has been on the rise in recent years. In this review, the authors' aim was to assess the effectiveness of current recommendations to parents on this exceedingly common problem through a comprehensive literature search. Additionally, the current treatment options and the most recent ...

journal_title：Neurosurgical focus

authors： Shweikeh F,Nuño M,Danielpour M,Krieger MD,Drazin D

更新日期：2013-10-01 00:00:00

abstract：:Lumbar discectomy is the most common surgical procedure performed in neurosurgery clinics. Such a large number of procedures underscore not only the prevalence of conditions such as intervertebral disc herniation, but also the strong belief of surgeons that the operation does provide benefits to patients suffering fro...

journal_title：Neurosurgical focus

authors： Erman T,Tuna M,Göçer AI,Idan F,Akgül E,Zorludemir S

更新日期：2001-11-15 00:00:00

abstract：:Several cases of congenital or acquired temporal encephaloceles have been reported in the literature as the causative mechanism of simple and/or complex partial seizures. In this report the authors describe a rare case of spontaneous parietal encephalocele presenting with simple partial seizures and progressively incr...

journal_title：Neurosurgical focus

authors： Fountas KN,Smith JR,Jenkins PD,Murro AM

更新日期：2005-09-15 00:00:00

abstract：:OBJECTIVE Commercially available processed nerve allografts have been shown to be inferior to autografts in previous animal studies. The authors hypothesized that combining different processing and storage techniques will result in improved nerve ultrastructure preservation, lower immunogenicity, and minimized cellula...

journal_title：Neurosurgical focus

authors： Hundepool CA,Nijhuis TH,Kotsougiani D,Friedrich PF,Bishop AT,Shin AY

更新日期：2017-03-01 00:00:00

abstract：:Brain-machine interface (BMI) is the latest solution to a lack of control for paralyzed or prosthetic limbs. In this paper the authors focus on the design of anatomical robotic hands that use BMI as a critical intervention in restorative neurosurgery and they justify the requirement for lower-level neuromusculoskeleta...

journal_title：Neurosurgical focus

authors： Matsuoka Y,Afshar P,Oh M

更新日期：2006-05-15 00:00:00

abstract：:OBJECTIVE The long-term effects on adjacent-segment pathology after nonfusion dynamic stabilization is unclear, and, in particular, changes at the adjacent facet joints have not been reported in a clinical study. This study aims to compare changes in the adjacent facet joints after lumbar spinal surgery. METHODS Patie...

journal_title：Neurosurgical focus

authors： Lee SE,Jahng TA,Kim HJ

更新日期：2016-01-01 00:00:00

abstract：:Vein of Galen malformations are rare congenital intracranial vascular malformations. Based on reports in the literature, spontaneous thrombosis or regression of these lesions is rare. Patients have variable outcomes from an asymptomatic course to death. The reasons behind spontaneous thrombosis are not entirely unders...

journal_title：Neurosurgical focus

authors： Moftakhar P,Danielpour M,Maya M,Alexander MJ

更新日期：2009-11-01 00:00:00

abstract：:In this article the authors attempt to raise awareness of the pitfalls and controversial issues in nerve tumor surgery. In a case-guided format, examples of ambiguous findings, inappropriate tumor removal, repeated surgery, and nerve repairs are provided. The authors also discuss the need to establish a correct diagno...

journal_title：Neurosurgical focus

authors： Kretschmer T,Antoniadis G,Heinen C,Börm W,Scheller C,Richter HP,Koenig RW

更新日期：2007-06-15 00:00:00

abstract：OBJECTIVE:Convection-enhanced delivery (CED) and osmotic pump delivery both have been promoted as promising techniques to deliver drugs to pediatric diffuse intrinsic pontine gliomas (DIPGs). Correspondingly, the aim of this study was to understand how infusate molecular weight (MW), duration of delivery, and mechanism...

journal_title：Neurosurgical focus

authors： Rechberger JS,Power EA,Lu VM,Zhang L,Sarkaria JN,Daniels DJ

更新日期：2020-01-01 00:00:00

abstract：:OBJECTIVE In this study the authors describe the technical considerations and feasibility of transforaminal discectomy and foraminoplasty for the treatment of lumbar radiculopathy in patients who have herniated discs at the thoracolumbar junction. METHODS After institutional review board approval, charts from 3 consec...

journal_title：Neurosurgical focus

authors： Telfeian AE,Jasper GP,Oyelese AA,Gokaslan ZL

更新日期：2016-02-01 00:00:00

abstract：:Surgical removal remains one of the key treatment modalities for vestibular schwannomas. A team approach between a neurotologist and a neurosurgeon offers the patient the expertise of both specialties and maximizes the chances for an optimal outcome. Vestibular schwannomas can typically be resected through 1 of 3 main...

journal_title：Neurosurgical focus

authors： Chamoun R,MacDonald J,Shelton C,Couldwell WT

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Nerve root injuries associated with anterior lumbar interbody fusion (ALIF) are uncommonly reported in the literature. This case series and review aims to describe the etiology of L5 nerve root injury following ALIF at L5-S1. METHODS:The authors performed a single-center retrospective review of prospectively...

journal_title：Neurosurgical focus

authors： Dowlati E,Alexander H,Voyadzis JM

更新日期：2020-09-01 00:00:00

abstract：OBJECT:Hypothalamic hamartomas (HHs) are devastating lesions causing refractory epilepsy, rage attacks, social ineptitude, and precocious puberty. Microsurgical and/or endoscopic resection offers an excellent risk/benefit profile for cure or improvement of epilepsy. METHODS:The authors reviewed a prospective database ...

journal_title：Neurosurgical focus

authors： Wait SD,Abla AA,Killory BD,Nakaji P,Rekate HL

更新日期：2011-02-01 00:00:00