Optimizing decellularization techniques to create a new nerve allograft: an in vitro study using rodent nerve segments.

abstract：:Acute ischemic stroke is now considered a neurological emergency for which there are new therapies. Neurosurgeons and neurologists need to remain apprised of advances in this field. The authors discuss approved and emerging therapies for patients suffering from acute ischemic stroke, based on a review of recent public...

journal_title：Neurosurgical focus

authors： Kindler DD,Lopez GA,Worrall BB,Johnston KC

更新日期：2000-05-15 00:00:00

abstract：OBJECT:This review summarizes the continuous study of low-power laser radiation treatment of a severely injured peripheral nerve. Laser phototherapy was applied as a supportive factor for accelerating and enhancing axonal growth and regeneration after injury or a reconstructive peripheral nerve procedure. In nerve cell...

journal_title：Neurosurgical focus

authors： Rochkind S

更新日期：2009-02-01 00:00:00

abstract：:Vein of Galen malformations are rare congenital intracranial vascular malformations. Based on reports in the literature, spontaneous thrombosis or regression of these lesions is rare. Patients have variable outcomes from an asymptomatic course to death. The reasons behind spontaneous thrombosis are not entirely unders...

journal_title：Neurosurgical focus

authors： Moftakhar P,Danielpour M,Maya M,Alexander MJ

更新日期：2009-11-01 00:00:00

abstract：OBJECT:Experience with minimal-access surgical approaches for revision lumbar surgery has not been previously reported. METHODS:During a 7-month period, 10 consecutive patients with recurrent disc herniations underwent revision operations in which microendoscopic discectomy (MED) was performed. Perioperative data and ...

journal_title：Neurosurgical focus

authors： Le H,Sandhu FA,Fessler RG

更新日期：2003-09-15 00:00:00

abstract：:Trepanation is the process by which a hole is drilled into the skull, exposing the intracranial contents for either medical or mystical purposes. It represents one of the oldest surgical procedures, and its practice was widespread in many ancient cultures and several parts of the world. Trepanation was used in ancient...

journal_title：Neurosurgical focus

authors： Missios S

更新日期：2007-01-01 00:00:00

abstract：:Revision spinal surgery is usually indicated in cases of persistent or recurrent symptoms related to neural compression, spinal deformity, or construct failure. An understanding of fundamental biomechanical principles of both spinal decompression and reconstructive strategies is essential to avoid unnecessary subseque...

journal_title：Neurosurgical focus

authors： Schlenk RP,Stewart T,Benzel EC

更新日期：2003-09-15 00:00:00

abstract：:Tumor-associated epilepsy is an important contributor to morbidity in patients with brain tumors. Proposed pathophysiological mechanisms to explain these effects range from neuronal and glial dysfunction to deranged vascular homeostasis, to ionic and pH changes. Perilesional tissue alterations play a vital role in the...

journal_title：Neurosurgical focus

authors： Rajneesh KF,Binder DK

更新日期：2009-08-01 00:00:00

abstract：:Spine surgery has been disproportionately impacted by medical liability and malpractice litigation, with the majority of claims and payouts related to procedural error. One common area for the potential avoidance of malpractice claims and subsequent payouts involves misplaced pedicle and/or lateral mass instrumentatio...

journal_title：Neurosurgical focus

authors： Sankey EW,Mehta VA,Wang TY,Than TT,Goodwin CR,Karikari IO,Shaffrey CI,Abd-El-Barr MM,Than KD

更新日期：2020-11-01 00:00:00

abstract：:Decompressive craniectomy is widely used to treat intracranial hypertension following traumatic brain injury (TBI). Two randomized trials are currently underway to further evaluate the effectiveness of decompressive craniectomy for TBI. Complications of this procedure have major ramifications on the risk-benefit balan...

journal_title：Neurosurgical focus

authors： Stiver SI

更新日期：2009-06-01 00:00:00

abstract：:Sacral chordomas are relatively rare, locally invasive, malignant neoplasms. Although metastasis is infrequent at presentation, the prognosis for patients with chordoma of the sacrum is reported to be poor and attributable in most cases to intralesional resection. The value of adjuvant treatment is uncertain, and rese...

journal_title：Neurosurgical focus

authors： Fourney DR,Gokaslan ZL

更新日期：2003-08-15 00:00:00

abstract：OBJECTIVE:Global outbreak of the novel coronavirus disease 2019 (COVID-19) has forced healthcare systems worldwide to reshape their facilities and protocols. Although not considered the frontline specialty in managing COVID-19 patients, neurosurgical service and training were also significantly affected. This article f...

journal_title：Neurosurgical focus

authors： Suryaningtyas W,Wahyuhadi J,Turchan A,Subagio EA,Parenrengi MA,Apriawan T,Al Fauzi A,Bajamal AH

更新日期：2020-12-01 00:00:00

abstract：:Central skull base lesions in the upper retroclival and petroclival regions can be challenging to access because of their location anterior to the brainstem. Several transpetrosal approaches have been developed to access the petroclival junction, including anterior petrosal (anterior petrosectomy), posterior petrosal ...

journal_title：Neurosurgical focus

authors： Zhao JC,Liu JK

更新日期：2008-01-01 00:00:00

abstract：:The development of alternative approaches to spine disorders marked an evolutionary change in the methods by which surgeons address diseases that affect the ventral portion of the spine. From the advent of spinal surgery until quite recently, physicians used posterior approaches almost exclusively for the treatment of...

journal_title：Neurosurgical focus

authors： Lifshutz J,Lidar Z,Maiman D

更新日期：2004-01-15 00:00:00

abstract：OBJECT:Tethering of the spinal cord has been a recognized cause of neurological symptoms in pediatric patients and is increasingly being recognized as a cause of symptoms in adults as well. The pathophysiology surrounding spinal cord tethering has begun to be understood in the pediatric population but is still unclear ...

journal_title：Neurosurgical focus

authors： Stetler WR Jr,Park P,Sullivan S

更新日期：2010-07-01 00:00:00

abstract：:Frontal sinus fractures are heterogeneous, and management of these fractures is often modified based on injury pattern and institutional experience. The optimal initial treatment of frontal sinus fractures is controversial. Treatment strategies are aimed at correcting cosmetic deformity, as well as at preventing delay...

journal_title：Neurosurgical focus

authors： Castro B,Walcott BP,Redjal N,Coumans JV,Nahed BV

更新日期：2012-06-01 00:00:00

abstract：:OBJECTIVE Reservoirs integrated into hydrocephalus shunts are commonly used for the removal of CSF and for intra-ventricular pressure measurement. Pumping with the reservoir to diagnose shunt sufficiency is still a matter of controversy. The authors describe an improved flushing device and its characteristic features ...

journal_title：Neurosurgical focus

authors： Schlosser HG,Crawack HJ,Miethke C,Knitter T,Zeiner A,Sprung C

更新日期：2016-09-01 00:00:00

abstract：:Intracranial electroencephalography monitoring of the insula is an important tool in the investigation of the insula in medically intractable epilepsy and has been shown to be safe and reliable. Several methods of placing electrodes for insular coverage have been reported and include open craniotomy as well as stereot...

journal_title：Neurosurgical focus

authors： Desai A,Bekelis K,Darcey TM,Roberts DW

更新日期：2012-03-01 00:00:00

abstract：:OBJECTIVE The microscopic transoral, endoscopic transnasal, and endoscopic transoral approaches are used alone and in combination for a variety of craniovertebral junction (CVJ) pathologies. The endoscopic transoral approach provides a more direct exposure that is not restricted by the nasal cavity, pterygoid plates, ...

journal_title：Neurosurgical focus

authors： Chan AK,Benet A,Ohya J,Zhang X,Vogel TD,Flis DW,El-Sayed IH,Mummaneni PV

更新日期：2016-02-01 00:00:00

abstract：OBJECT:Parallel advancements in image guidance technology and minimal access techniques continue to push the frontiers of minimally invasive spine surgery (MISS). While traditional intraoperative imaging remains widely used, newer platforms, such as 3D-fluoroscopy, cone-beam CT, and intraoperative CT/MRI, have enabled ...

journal_title：Neurosurgical focus

authors： Moses ZB,Mayer RR,Strickland BA,Kretzer RM,Wolinsky JP,Gokaslan ZL,Baaj AA

更新日期：2013-08-01 00:00:00

abstract：:Cervical dural arteriovenous fistulas (dAVFs) are a rare cause of intracranial subarachnoid hemorrhage (SAH) but should be considered when other sources are not found. Subarachnoid hemorrhage caused by dAVF is thought to occur as a result of venous hypertension in most cases. The clinical presentation, acute onset of ...

journal_title：Neurosurgical focus

authors： Fassett DR,Rammos SK,Patel P,Parikh H,Couldwell WT

更新日期：2009-01-01 00:00:00

abstract：:Our understanding of glioblastoma multiforme (GBM), the most common form of primary brain cancer, has been significantly advanced by recent efforts to characterize the cancer genome using unbiased high-throughput sequencing analyses. While these studies have documented hundreds of mutations, gene copy alterations, and...

journal_title：Neurosurgical focus

authors： Kahle KT,Kozono D,Ng K,Hsieh G,Zinn PO,Nitta M,Chen CC

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The recognition that neurosurgeons harbor great potential to advocate for the care of individuals with neural tube defects (NTDs) globally has sounded as a clear call to action; however, neurosurgical care and training in low- and middle-income countries (LMICs) present unique challenges that must be consider...

journal_title：Neurosurgical focus

authors： Gandy K,Castillo H,Rocque BG,Bradko V,Whitehead W,Castillo J

更新日期：2020-03-01 00:00:00

abstract：:Degenerative lumbar spinal stenosis is a common condition affecting middle-aged and elderly people. Significant controversy exists concerning the appropriate indications for fusion following decompressive surgery. The purpose of this report is to compare the clinical outcomes of patients who were and were not treated ...

journal_title：Neurosurgical focus

authors： Fox MW,Onofrio BM

更新日期：1997-08-15 00:00:00

abstract：:Anterior screw fixation of Type II odontoid fractures provides immediate stabilization of the cervical spine while preserving C1-2 motion. This technique has a high fusion rate, but can be technically challenging. The authors identify key points that should be taken into account to maximize the chance for a favorable ...

journal_title：Neurosurgical focus

authors： Mazur MD,Mumert ML,Bisson EF,Schmidt MH

更新日期：2011-10-01 00:00:00

abstract：OBJECT:Loss-of-function mutations in CCM genes are frequently detected in familial cerebral cavernous malformations (CCMs). However, the current functional studies of the CCM genes in vitro have been performed mostly in commercially purchased normal cell lines and the results appeared discrepant. The fact that the cere...

journal_title：Neurosurgical focus

authors： Zhu Y,Wu Q,Xu JF,Miller D,Sandalcioglu IE,Zhang JM,Sure U

更新日期：2010-09-01 00:00:00

abstract：OBJECT:The safety and effectiveness of osteogenic protein (OP)-1 putty (recombinant human bone morphogenetic protein-7) in promoting fusion in complex spinal cases was studied in nine cases. METHODS:The authors prospectively evaluated nine patients requiring spinal fusion in whom there were medical risk factors that w...

journal_title：Neurosurgical focus

authors： Govender PV,Rampersaud YR,Rickards L,Fehlings MG

更新日期：2002-12-15 00:00:00

abstract：OBJECTIVE:Establishing the neurological localization doctrine for the contralateral hemispheric control of motor functions in the second half of the 19th century, researchers faced the challenge of recognizing false localizing signs, in particular paradoxical or ipsilateral hemiparesis (IH). Despite tremendous progress...

journal_title：Neurosurgical focus

authors： Carrasco-Moro R,Castro-Dufourny I,Martínez-San Millán JS,Cabañes-Martínez L,Pascual JM

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Nerve root injuries associated with anterior lumbar interbody fusion (ALIF) are uncommonly reported in the literature. This case series and review aims to describe the etiology of L5 nerve root injury following ALIF at L5-S1. METHODS:The authors performed a single-center retrospective review of prospectively...

journal_title：Neurosurgical focus

authors： Dowlati E,Alexander H,Voyadzis JM

更新日期：2020-09-01 00:00:00

abstract：:Intraoperative optical imaging (IOI) is a marker-free, contactless, and noninvasive imaging technique that is able to visualize metabolic changes of the brain surface following neuronal activation. Although it has been used in the past mainly for the identification of functional brain areas under general anesthesia, t...

journal_title：Neurosurgical focus

authors： Oelschlägel M,Meyer T,Morgenstern U,Wahl H,Gerber J,Reiß G,Koch E,Steiner G,Kirsch M,Schackert G,Sobottka SB

更新日期：2020-02-01 00:00:00

abstract：:Economic evaluations provide a decision-making framework in which outcomes (benefits) and costs are assessed for various alternative options. Although the interest in complete and partial economic evaluations has increased over the past 2 decades, the quality of studies has been marginal due to methodological challeng...

journal_title：Neurosurgical focus

authors： McLaughlin N,Ong MK,Tabbush V,Hagigi F,Martin NA

更新日期：2014-11-01 00:00:00