The natural history of unruptured intracranial aneurysms.

Abstract:

:Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Mocco J,Komotar RJ,Lavine SD,Meyers PM,Connolly ES,Solomon RA

doi

10.3171/foc.2004.17.5.3

subject

Has Abstract

pub_date

2004-11-15 00:00:00

pages

E3

issue

5

issn

1092-0684

pii

170503

journal_volume

17

pub_type

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