Abstract：
:Chronic pain is one of the major causes of disability in the general population. Even though there are effective treatment options available for reducing symptoms, these treatments often do not have consistent lasting effects. As the usage of mobile devices has increased enormously during the last few years, mobile application-based treatment options are widespread. Such app-based programs are not yet empirically proven but might enable patients to become more independent in their pain management in order to prevent relapse. The aim of this meta-analysis was to summarize the literature on mobile application-based interventions for chronic pain patients. Therefore, three electronic bibliographic databases, PubMed, PsycINFO, and Web of Science, were searched for studies that investigated the effectiveness of mobile application-based intervention for chronic pain on pain intensity. The final sample comprised twenty-two studies, with a total of 4679 individuals. Twelve of these twenty-two studies used a randomized control trial (RCT) design, while ten studies only used an observational design. For all twenty-two studies, a small but significant effect (d = -0.40) was found when compared to baseline measures or control groups. The results suggest that apps-based treatment can be helpful in reducing pain, especially in the long-term.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Pfeifer AC,Uddin R,Schröder-Pfeifer P,Holl F,Swoboda W,Schiltenwolf Mdoi
10.3390/jcm9113557subject
Has Abstractpub_date
2020-11-05 00:00:00issue
11issn
2077-0383pii
jcm9113557journal_volume
9pub_type
杂志文章,评审abstract：:A major challenge of cell-based therapy for cartilage lesions is the preservation of the chondrogenic phenotype during ex vivo cell cultivation. In this in vitro study, the chondro-inductive capacity of two different hyaline cartilage-conditioned cell culture media on human chondrocytes in 3D spheroids was determined....
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9092798
更新日期：2020-08-30 00:00:00
abstract：:The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed YWHAZ (encoding 14-3-3ζ) as a candidate gene for autism spectrum disorder (ASD) through a whole-exome sequencing study, which identified a frameshift variant within the gene (...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9061851
更新日期：2020-06-13 00:00:00
abstract：:We examined the association between self-rated health (SRH), a subjective measure of an individual's health status, and the incidence of metabolic abnormalities, as well as the effect of obesity on this association in metabolically healthy individuals. The cohort study included 85,377 metabolically healthy men and wom...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8010034
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Nine percent of all cases of tuberculosis are bone and joint tuberculosis (BJTB). BJTB occurs in two main forms: spinal (STB) and extraspinal (ESTB). The aim of this study was to compare STB with ESTB in terms of diagnosis, treatment and outcomes. METHODS:We collected demographic, clinical, microbiological,...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9082529
更新日期：2020-08-05 00:00:00
abstract：:Epistaxis is a common debilitating manifestation in hereditary hemorrhagic telangiectasia (HHT), due to mucocutaneous telangiectases. The epistaxis can be difficult to control despite available treatments. Dysregulated angiogenesis has been shown to be associated with telangiectases formation. Topical propranolol has ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9103130
更新日期：2020-09-28 00:00:00
abstract：:There are no reliable, non-invasive methods to accurately measure cardiac output (CO) in septic patients. MostCare (Vytech Health™, Vygon, Padova, Italy), is a beat-to-beat, self calibrated method for CO measurement based on continuous analysis of reflected arterial pressure waveforms. We enrolled 40 patients that wer...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm10020213
更新日期：2021-01-09 00:00:00
abstract：:Osteogenesis imperfecta (OI) is a connective tissue disorder that is characterized by low bone density leading to recurrent fractures. The efficacy of the anti-resorption drug denosumab for OI with osteoporosis is still largely unknown. We herein describe the clinical outcomes of eight osteoporotic cases of OI to exam...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7120479
更新日期：2018-11-24 00:00:00
abstract：:Patients diagnosed with traumatic or non-traumatic spinal pain and idiopathic scoliosis frequently suffer from imbalance. The evaluation of the perception of verticality by means of visual tests emerges as a quick and easy tool for clinical management of the balance disorders. Several studies have assessed the visual ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9061725
更新日期：2020-06-03 00:00:00
abstract：BACKGROUND:It can be hypothetically assumed that maternal and perinatal factors influence the intestinal barrier. METHODS:The study was conducted with 100 healthy, full-term newborns breastfed in the first week of life, with similar analyses for their mothers. Zonulin and calprotectin levels were used as intestinal pe...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040473
更新日期：2019-04-07 00:00:00
abstract：:The aim of this study was to compare surgical and refractive outcomes between phacotrabeculectomy (P-Trab) and phaco with Ex-PRESS (P-Ex-PRESS) for glaucoma at a 6-month follow-up. This prospective randomized controlled trial included 81 eyes; 43 eyes (53%) and 38 eyes (47%) were assigned to the P-Ex-PRESS and P-Trab ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm10030424
更新日期：2021-01-22 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the association between acute kidney injury (AKI) and in-hospital mortality (IHM) in a large nationwide cohort of elderly subjects in Italy. METHODS:We analyzed the hospitalization data of all patients aged ≥65 years, who were discharged with a diagnosis of AKI, whic...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8091371
更新日期：2019-09-02 00:00:00
abstract：:To bridge the translational gap between recent discoveries of distinct molecular phenotypes of pancreatic cancer and tangible improvements in patient outcome, there is an urgent need to develop strategies and tools informing and improving the clinical decision process. Radiomics and machine learning approaches can off...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9030724
更新日期：2020-03-07 00:00:00
abstract：:With the improvement in survival rate, cardiotoxicity has emerged as a significant adverse effect of cancer therapy. Early diagnosis of subclinical cardiac injury may allow the initiation of cardioprotective therapy and preventing the interruption of optimal cancer therapy and the development of irreversible cardiac d...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm10010154
更新日期：2021-01-05 00:00:00
abstract：:(1) Background: We evaluated macular ganglion cell layer-inner plexiform layer (GCL-IPL) thickness in patients with primary macula-off rhegmatogenous retinal detachment (RRD) treated with scleral buckling (SB) or pars plana vitrectomy (PPV) using spectral domain optical coherence tomography (SD-OCT). (2) Methods: In t...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9051411
更新日期：2020-05-10 00:00:00
abstract：:The idea of right heart catheterization (RHC) grew in the milieu of modern thinking about the cardiovascular system, influenced by the experiments of William Harvey, which were inspired by the treatises of Greek philosophers like Aristotle and Gallen, who made significant contributions to the subject. RHC was first di...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8091331
更新日期：2019-08-28 00:00:00
abstract：:Sepsis is a major cause of death in intensive care units worldwide. The acute phase of sepsis is often accompanied by sepsis-associated encephalopathy, which is highly associated with increased mortality. Moreover, in the chronic phase, more than 50% of surviving patients suffer from severe and long-term cognitive def...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9030703
更新日期：2020-03-05 00:00:00
abstract：:Hypothermic machine perfusion (HMP) has been introduced as an alternative to static cold storage (SCS) in kidney transplantation, but its true benefit in the clinical routine remains incompletely understood. The aim of this study was to assess the effect of HMP vs. SCS in kidney transplantation. All kidney transplants...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9072311
更新日期：2020-07-21 00:00:00
abstract：BACKGROUND:Heart rate variability (HRV) as an accurate, noninvasive measure of the Autonomous Nervous System (ANS) can reflect mental health (e.g., stress, depression, or anxiety). Tai Chi and Yoga (Tai Chi/Yoga), as the most widely practiced mind⁻body exercises, have shown positive outcomes of mental health. To date, ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm7110404
更新日期：2018-10-31 00:00:00
abstract：:After decades of pioneering and improvement, kidney transplantation is now the renal replacement therapy of choice for most patients with end-stage kidney disease (ESKD). Where focus has traditionally been on surgical techniques and immunosuppressive treatment with prevention of rejection and infection in relation to ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9061911
更新日期：2020-06-18 00:00:00
abstract：:Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides i...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm4020343
更新日期：2015-02-12 00:00:00
abstract：:Ticagrelor, an antiplatelet adenosine diphosphate (ADP)-P2Y12 receptor antagonist, increases the risk of bleeding. Its management is challenging because platelet transfusion is ineffective and no specific antidote is currently available. Epinephrine, a vasopressor catecholamine prescribed during shock, restores platel...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9030809
更新日期：2020-03-16 00:00:00
abstract：:The new allocation criteria classify patients on veno-arterial extracorporeal membranous oxygenation (VA-ECMO) as the highest priority for receiving orthotopic heart transplantation (OHT) especially if they are considered not candidates for ventricular assist devices. The outcomes of patients who receive ventricular a...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8050572
更新日期：2019-04-26 00:00:00
abstract：:Duchenne muscular dystrophy (DMD), the most severe form of dystrophinopathy, is quite homogeneous with regards to its causative biochemical defect, i.e., complete dystrophin deficiency, but not so much with regards to its phenotype. For instance, muscle weakness progresses to the loss of independent ambulation at a va...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8050649
更新日期：2019-05-10 00:00:00
abstract：:Organ transplantation is a new issue in medical science. It is an important achievement and a sign of the progression and ability of medical centers around the world. Governments, populations, the medical community and people involved in culture, art, and media all have a decisive role in the culture of organ donation...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm7030045
更新日期：2018-03-05 00:00:00
abstract：:Neovascular age related macular degeneration (nAMD) leads to severe vision loss worldwide and is characterized by the formation of choroidal neovascularization (CNV) and fibrosis. In the current study, we aimed to investigate the effect of blockade for platelet derived growth factor receptor-β (PDGFR-β) on the formati...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9072242
更新日期：2020-07-15 00:00:00
abstract：:The aim of the study was to investigate ultrasound tissue characterization of carotid plaques in subjects with and without diabetes type 1 (T1D). B-mode carotid ultrasound was performed to assess the presence and type of plaque in a group of 340 subjects with and 304 without T1D, all of them without cardiovascular dis...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040424
更新日期：2019-03-28 00:00:00
abstract：:Minimal residual disease evaluation refers to a series of molecular and immunophenotypical techniques aimed at detecting submicroscopic disease after therapy. As such, its application in acute myeloid leukemia has greatly increased our ability to quantify treatment response, and to determine the chemosensitivity of th...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm6060057
更新日期：2017-06-03 00:00:00
abstract：:The use of targeted agents and immunotherapy for the treatment of advanced non-small-cell lung cancer (NSCLC) has made it mandatory to characterize tumor tissue for patient selection. Moreover, the development of agents that are active against specific resistance mechanisms arising during treatment make it equally imp...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8070998
更新日期：2019-07-09 00:00:00
abstract：:Patients with kidney transplantation often have a worse quality of life than the general population. One of the reasons for this, in male patients, is the high prevalence of erectile dysfunction. This is mainly due to the presence of comorbidities, surgery for kidney transplantation, adverse drug effects, psychologica...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9061991
更新日期：2020-06-25 00:00:00
abstract：BACKGROUND:Asthma patterns are not well established in epidemiological studies. AIM:To assess asthma patterns and risk factors in an adult general population sample. METHODS:In total, 452 individuals reporting asthma symptoms/diagnosis in previous surveys participated in the AGAVE survey (2011-2014). Latent transitio...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9113632
更新日期：2020-11-11 00:00:00
