Frailty in major trauma study (FRAIL-T): a study protocol to determine the feasibility of nurse-led frailty assessment in elderly trauma and the impact on outcome in patients with major trauma.

abstract：OBJECTIVE:Danish medical registries are widely used for cardiovascular research, but little is known about the data quality of cardiac interventions. We computed positive predictive values (PPVs) of codes for cardiac examinations, procedures and surgeries registered in the Danish National Patient Registry during 2010-2...

journal_title：BMJ open

authors： Adelborg K,Sundbøll J,Munch T,Frøslev T,Sørensen HT,Bøtker HE,Schmidt M

更新日期：2016-12-09 00:00:00

abstract：INTRODUCTION:High-flow nasal oxygen (HFNO) use in adults hospitalised with acute respiratory failure (ARF) is increasing. However, evidence to support widespread use of HFNO compared with non-invasive ventilation (NIV) and conventional oxygen therapy (COT) is unclear. This protocol describes the methods for a systemati...

journal_title：BMJ open

authors： Baldomero AK,Melzer A,Greer N,Majeski BN,Macdonald R,Wilt TJ

更新日期：2020-02-12 00:00:00

abstract：OBJECTIVES:Head injury is a common reason for emergency department (ED) attendance. Around 1% of patients have life-threatening injuries, while 80% of patients are discharged. National guidelines (Scottish Intercollegiate Guidelines Network (SIGN)) were introduced in Scotland with the aim of achieving early identificat...

journal_title：BMJ open

authors： Marincowitz C,Lecky FE,Morris E,Allgar V,Sheldon TA

更新日期：2018-12-22 00:00:00

abstract：INTRODUCTION:Postnatal mental health problems, which are an international public health priority, are a suitable target for preventive approaches. The financial burden of these disorders is borne across sectors in society, including health, early childhood, education, justice and the workforce. This paper describes the...

journal_title：BMJ open

authors： Ride J,Rowe H,Wynter K,Fisher J,Lorgelly P

更新日期：2014-10-03 00:00:00

abstract：INTRODUCTION:The diabetes mellitus (DM) epidemic is a major public health concern globally, with the highest-burden in low-income and middle-income countries (LMICs). Diabetic retinopathy (DR) is a microvascular complication of diabetes, and if left untreated can lead to visual impairment and blindness. Epidemiological...

journal_title：BMJ open

authors： Curran K,Piyasena P,Congdon N,Duke L,Malanda B,Peto T

更新日期：2020-09-18 00:00:00

abstract：OBJECTIVES:We examined the association of workplace social capital (WSC), including structural and cognitive dimensions, with refraining from seeking medical care (RSMC) among Japanese employees. DESIGN:One-year prospective cohort study. SETTING AND PARTICIPANTS:We surveyed 8770 employees (6881 men and 1889 women) ag...

journal_title：BMJ open

authors： Inoue A,Tsutsumi A,Eguchi H,Kachi Y,Shimazu A,Miyaki K,Takahashi M,Kurioka S,Enta K,Kosugi Y,Totsuzaki T,Kawakami N

更新日期：2020-08-03 00:00:00

abstract：OBJECTIVE:This study was designed to examine the prevalence of unilateral and bilateral diagonal earlobe creases (DELCs) with respect to the diagnosis of coronary heart disease (CHD). METHODS:A total of 558 consecutive participants (402 males and 156 females) aged 36-91 years who underwent coronary angiography were en...

journal_title：BMJ open

authors： Wang Y,Mao LH,Jia EZ,Li ZY,Ding XQ,Ge PC,Liu Z,Zhu TB,Wang LS,Li CJ,Ma WZ,Yang ZJ

更新日期：2016-02-11 00:00:00

abstract：INTRODUCTION:As a combination of visual stimulation and motor imagery, mirror visual feedback (MVF) is an effective treatment for motor impairment after stroke; however, few studies have investigated its effects on relevant cognitive processes such as visual perception and motor imagery. Camera-based MVF (camMVF) overc...

journal_title：BMJ open

authors： Ding L,Wang X,Guo X,Chen S,Wang H,Cui X,Rong J,Jia J

更新日期：2019-03-03 00:00:00

abstract：OBJECTIVE:To estimate the impact of state-level supplements of the Earned Income Tax Credit (EITC) on mortality in the USA. The EITC supplements the wages of lower-income workers by providing larger returns when taxes are filed. SETTING:Nationwide sample spanning 25 cohorts of people across every state in the USA. PA...

journal_title：BMJ open

authors： Muennig P,Vail D,Hakes JK

更新日期：2020-08-20 00:00:00

abstract：OBJECTIVES:Healthcare professionals are expected to firmly ground their practice in sound evidence. That implies that they know and use evidence-based medicine (EBM). In this study, our aim was to know how often health professionals actually made use of EBM in their daily practice. DESIGN:A questionnaire survey of hea...

journal_title：BMJ open

authors： Lafuente-Lafuente C,Leitao C,Kilani I,Kacher Z,Engels C,Canouï-Poitrine F,Belmin J

更新日期：2019-03-30 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a model of rural community health service (CHS) on the use and acceptability of primary healthcare services. DESIGN:Quasi-experimental. SETTING:Two adjacent rural counties in China. PARTICIPANTS:5842 residents in 2009 and 3807 in 2010 from 980 households in 7 intervention township...

journal_title：BMJ open

authors： Liu Y,Yuan Z,Liu Y,Jayasinghe UW,Harris MF

更新日期：2014-02-28 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) affects 10% of patients undergoing cardiac surgery and is an independent risk factor for all-cause mortality, ischaemic stroke and heart failure. Surgical AF ablation has been shown to significantly improve maintenance of sinus rhythm, however, small to medium size trials conducted...

journal_title：BMJ open

authors： McClure GR,Belley-Cote EP,Singal RK,Jaffer IH,Dvirnik N,An KR,Fortin G,Spence J,Whitlock RP

更新日期：2016-11-02 00:00:00

abstract：OBJECTIVES:Patients with idiopathic intracranial hypertension (IIH) usually require multiple lumbar punctures (LPs) during the course of their disease, and often report significant morbidity associated with the procedure. The aim of this study was to assess the patient's experience of diagnostic LP in IIH. DESIGN, MET...

journal_title：BMJ open

authors： Scotton WJ,Mollan SP,Walters T,Doughty S,Botfield H,Markey K,Yiangou A,Williamson S,Sinclair AJ

更新日期：2018-05-30 00:00:00

abstract：OBJECTIVES:To determine the proportion of maternal and perinatal mortality and morbidity cases, identified by the Perinatal and Maternal Mortality Review Committee (PMMRC), that are also reported within the annual serious adverse events (SAEs) reports published by the Health Quality and Safety Commission (HQSC). SETTI...

journal_title：BMJ open

authors： Farquhar C,Armstrong S,Kim B,Masson V,Sadler L

更新日期：2015-07-23 00:00:00

abstract：INTRODUCTION:Many countries are launching large-scale, digitally enabled change programmes as part of efforts to improve the quality, safety and efficiency of care. We have been commissioned to conduct an independent evaluation of a major national change programme, the Global Digital Exemplar (GDE) Programme, which aim...

journal_title：BMJ open

authors： Cresswell K,Sheikh A,Dean Franklin B,Krasuska M,Nguyen H,Hinder S,Lane W,Mozaffar H,Mason K,Eason S,Potts H,Williams R

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVE:To model the long-term cost-effectiveness of consuming milk powder fortified with potassium to decrease systolic blood pressure (SBP) and prevent cardiovascular events. DESIGN:A best case scenario analysis using a Markov model was conducted. PARTICIPANTS:8.67% of 50-79 year olds who regularly consume milk i...

journal_title：BMJ open

authors： Dainelli L,Xu T,Li M,Zimmermann D,Fang H,Wu Y,Detzel P

更新日期：2017-09-25 00:00:00

abstract：OBJECTIVES:Chromosome 9p21 single nucleotide polymorphism (SNP) is a susceptibility variant for acute myocardial infarction (AMI) in the primary prevention setting. However, it is controversial whether this SNP is also associated with recurrent myocardial infarction (ReMI) in the secondary prevention setting. The purpo...

journal_title：BMJ open

authors： Hara M,Sakata Y,Nakatani D,Suna S,Usami M,Matsumoto S,Ozaki K,Nishino M,Sato H,Kitamura T,Nanto S,Hamasaki T,Tanaka T,Hori M,Komuro I,OACIS Investigators.

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Current research on the perceptions of overdiagnosis or overdetection of breast cancer has largely been conducted outside of the USA and with women younger than 70 years.Therefore, we explored older women's perceptions about the concept of overdetection of breast cancer and its influence on future screening ...

journal_title：BMJ open

authors： Pappadis MR,Volk RJ,Krishnan S,Weller SC,Jaramillo E,Hoover DS,Giordano SH,Tan A,Sheffield KM,Housten AJ,Goodwin JS

更新日期：2018-06-14 00:00:00

abstract：OBJECTIVE:Canada is among the few countries in which e-cigarettes containing nicotine are prohibited. To date, there is little evidence on the prevalence and patterns of use of e-cigarettes in markets with product bans. The current study examines e-cigarette use among a sample of non-smokers and smokers in Canada. DES...

journal_title：BMJ open

authors： Shiplo S,Czoli CD,Hammond D

更新日期：2015-08-26 00:00:00

abstract：OBJECTIVE:How researchers' contributions relate to author order on the byline remains unclear. We sought to identify researchers' contributions associated with author order, and to explore the existence of author profiles. DESIGN:Observational study. SETTING:Published record. PARTICIPANTS:1139 authors of 119 researc...

journal_title：BMJ open

authors： Perneger TV,Poncet A,Carpentier M,Agoritsas T,Combescure C,Gayet-Ageron A

更新日期：2017-06-24 00:00:00

abstract：OBJECTIVES:To explore utilisation patterns of asthma medication before, during and after pregnancy as recorded in seven European population-based databases. DESIGN:A descriptive drug utilisation study. SETTING:7 electronic healthcare databases in Denmark, Norway, the Netherlands, Italy (Emilia Romagna and Tuscany), W...

journal_title：BMJ open

authors： Charlton RA,Pierini A,Klungsøyr K,Neville AJ,Jordan S,de Jong-van den Berg LT,Thayer D,Bos HJ,Puccini A,Hansen AV,Gini R,Engeland A,Nybo Andersen AM,Dolk H,Garne E

更新日期：2016-01-19 00:00:00

abstract：OBJECTIVES:Current strategies to prevent adult pneumococcal disease have been recently reviewed in Italy. We did a postlicensure study to estimate the direct vaccine effectiveness (VE) of the 13-valent pneumococcal conjugate vaccine (PCV13) against adult pneumococcal community-acquired pneumonia (pCAP). STUDY DESIGN:B...

journal_title：BMJ open

authors： Prato R,Fortunato F,Cappelli MG,Chironna M,Martinelli D

更新日期：2018-03-25 00:00:00

abstract：OBJECTIVE:To determine factors and outcomes associated with ultra-early surgery for poor-grade aneurysmal subarachnoid haemorrhage (aSAH). DESIGN:A multicentre retrospective analysis, observational study. SETTING:High-volume teaching hospitals (more than 150 aSAH cases per year). PARTICIPANTS:118 patients with World...

journal_title：BMJ open

authors： Zhao B,Zhao Y,Tan X,Cao Y,Wu J,Zhong M,Wang S

更新日期：2015-04-15 00:00:00

abstract：OBJECTIVES:This study aimed to assess the association of socioeconomic conditions with female fertility impairment among women who delivered a live birth. DESIGN:Cross-sectional analysis. SETTING:Population-based birth cohort (Generation XXI) assembled in 2005/2006 from five public maternity units in Porto Metropolit...

journal_title：BMJ open

authors： Correia S,Rodrigues T,Barros H

更新日期：2014-01-02 00:00:00

abstract：OBJECTIVE:To assess the prevalence of cerebral stroke in the general population of Beijing and its association with systemic risk factors and ocular diseases. SETTING:The population-based Beijing Eye Study was conducted in a rural and urban region of Beijing. PARTICIPANTS:With eligibility criteria of age 50+ years an...

journal_title：BMJ open

authors： Wang YX,Wei WB,Xu L,Jonas JB

更新日期：2020-09-10 00:00:00

abstract：INTRODUCTION:Ageing-related processes such as cellular senescence are believed to underlie the accumulation of diseases in time, causing (co)morbidity, including cancer, thromboembolism and stroke. Interfering with these processes may delay, stop or reverse morbidity. The aim of this study is to investigate the link be...

journal_title：BMJ open

authors： Henze L,Walter U,Murua Escobar H,Junghanss C,Jaster R,Köhling R,Lange F,Salehzadeh-Yazdi A,Wolkenhauer O,Hamed M,Barrantes I,Palmer D,Möller S,Kowald A,Heussen N,Fuellen G

更新日期：2020-12-17 00:00:00

abstract：OBJECTIVES:Isoniazid preventive therapy (IPT), for people living with HIV (PLHIV) is the proven and recommended intervention to avert tuberculosis (TB). In 2015, Nepal implemented 6 months of IPT for all PLHIV registered for HIV care in antiretroviral therapy (ART) centres. After programmatic implementation, there has ...

journal_title：BMJ open

authors： Dhungana GP,Thekkur P,Chinnakali P,Bhatta U,Pandey B,Zhang WH

更新日期：2019-05-29 00:00:00

abstract：INTRODUCTION:Osteoarthritis (OA) pathophysiology is driven in part by joint inflammation. Resveratrol has in vitro anti-inflammatory properties. We aim to assess the efficacy of oral resveratrol for knee pain at 3 months in people with knee OA. METHODS AND ANALYSIS:We will conduct a randomised double-blind placebo-con...

journal_title：BMJ open

authors： Nguyen C,Boutron I,Baron G,Coudeyre E,Berenbaum F,Poiraudeau S,Rannou F

更新日期：2017-09-29 00:00:00

abstract：OBJECTIVE:Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). When approved by the Food and Drug Administration (FDA) in 1988, a maximum daily dosage limit of 800 mg (eight tablets) of the 25/100 carbidopa/levodopa formulat...

journal_title：BMJ open

authors： Brodell DW,Stanford NT,Jacobson CE,Schmidt P,Okun MS

更新日期：2012-12-11 00:00:00

abstract：INTRODUCTION:The incidence of intrauterine growth restriction (IUGR) is estimated at about 3% of pregnancies, and it is associated with 30% of all perinatal mortality and severe morbidity with adverse neurodevelopmental and cardiovascular health consequences in adult life. Early onset IUGR represents 20%-30% of all cas...

journal_title：BMJ open

authors： Mazarico E,Peguero A,Camprubí M,Rovira C,Gomez Roig MD,Oros D,Ibáñez-Burillo P,Schoorlemmer J,Masoller N,Tàssies MD,Figueras F

更新日期：2018-10-23 00:00:00