OASIS-a randomised, placebo-controlled trial of oral glucocorticoids for leg pain in patients with acute sciatica: trial protocol.

abstract：OBJECTIVES:We conducted a retrospective review of patients with extrapulmonary small cell carcinomas (EPSCCs) to explore the distribution, treatments, patterns of relapse and outcomes by primary site. SETTING:We have reviewed the outcomes of one of the largest data sets of consecutive patients with EPSCC identified fr...

journal_title：BMJ open

authors： Gennatas S,Noble J,Stanway S,Gunapala R,Chowdhury R,Wotherspoon A,Benepal T,Popat S

更新日期：2015-01-14 00:00:00

abstract：OBJECTIVE:To compare the prevalence of work-related potential traumatic events (PTEs), support protocols and mental health symptoms across Dutch gynaecologists, orthopaedic surgeons and paediatricians. DESIGN:Cross-sectional study, supplementary analysis of combined data. SETTING:Nationwide survey between 2014 and 20...

journal_title：BMJ open

authors： Scheepstra KWF,Pauw HS,van Steijn ME,Stramrood CAI,Olff M,van Pampus MG

更新日期：2020-09-02 00:00:00

abstract：OBJECTIVES:Since population-based data on prognostic factors affecting survival in patients with breast cancer with bone metastasis (BM) are currently limited, we conducted this nationwide retrospective cohort study to examine the prognostic role of disease stage at breast cancer diagnosis and length of BM-free interva...

journal_title：BMJ open

authors： Cetin K,Christiansen CF,Sværke C,Jacobsen JB,Sørensen HT

更新日期：2015-04-29 00:00:00

abstract：INTRODUCTION:Dental caries (tooth decay) is a common disease in which the products of sugar metabolism by certain bacteria that populate the tooth surface induce the development and progression of lesions (cavities). This is a phase II single-centre randomised, double-blind, active-controlled, parallel-group trial to a...

journal_title：BMJ open

authors： Milgrom P,Tut O,Rothen M,Mancl L,Gallen M,Tanzer JM

更新日期：2017-06-30 00:00:00

abstract：INTRODUCTION:To realise universal health coverage in an ageing society, adequate provision of appropriately trained human resources is essential. The nurse practitioner (NP) is an autonomous and independent, advanced practice nurse capable of providing treatment and care that can be substituted for some aspects of a me...

journal_title：BMJ open

authors： Kanda M,Ota E,Fukuda H,Miyauchi S,Gilmour S,Kono Y,Nakagama E,Murashima S,Shibuya K

更新日期：2015-06-23 00:00:00

abstract：OBJECTIVE:In the field of palliative care (PC) as it is integrated into heart failure (HF) treatment, it is essential to explore the patient experience and build on this knowledge for the further development of PC practice and policy. Based on an intervention study, this paper explores what patients with HF find signif...

journal_title：BMJ open

authors： Roikjær SG,Simonÿ CP,Timm HU

更新日期：2020-12-31 00:00:00

abstract：INTRODUCTION:Poor air quality (AQ) is a global public health issue and AQ events can span across countries. Using emergency department (ED) syndromic surveillance from England and France, we describe changes in human health indicators during periods of particularly poor AQ in London and Paris during 2014. METHODS:Usin...

journal_title：BMJ open

authors： Hughes HE,Morbey R,Fouillet A,Caserio-Schönemann C,Dobney A,Hughes TC,Smith GE,Elliot AJ

更新日期：2018-04-19 00:00:00

abstract：OBJECTIVES:Immunisations against influenza and Bordetella pertussis infection are recommended to pregnant women in Valencia (Spain), yet vaccination rates remain low. Health literacy (HL) appears as a crucial factor in vaccination decision-making. We explored the relation between HL of pregnant women and decisions to r...

journal_title：BMJ open

authors： Castro-Sánchez E,Vila-Candel R,Soriano-Vidal FJ,Navarro-Illana E,Díez-Domingo J

更新日期：2018-07-06 00:00:00

abstract：INTRODUCTION:Postintensive care syndrome (PICS) is defined as a new or worsening impairment in cognition, mental health and physical function after critical illness. There is little evidence regarding treatment of patients with PICS; new directions for effective treatment strategies are urgently needed. Early physiothe...

journal_title：BMJ open

authors： Kondo Y,Fuke R,Hifumi T,Hatakeyama J,Takei T,Yamakawa K,Inoue S,Nishida O

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:The development of malignant pleural effusion (MPE) results in disabling breathlessness, pain and reduced physical capability with treatment a palliative strategy. Ambulatory management of MPE has the potential to improve quality of life (QoL). The OPTIMUM trial is designed to determine whether full outpat...

journal_title：BMJ open

authors： Sivakumar P,Douiri A,West A,Rao D,Warwick G,Chen T,Ahmed L

更新日期：2016-10-18 00:00:00

abstract：INTRODUCTION:Excessive prescribing after surgery has contributed to a public health crisis of opioid addiction and overdose in North America. However, the value of prescribing opioids to manage postoperative pain after surgical discharge remains unclear. We propose a systematic review and meta-analysis to assess the ex...

journal_title：BMJ open

authors： El-Kefraoui C,Olleik G,Chay MA,Kouyoumdjian A,Nguyen-Powanda P,Rajabiyazdi F,Do U,Derksen A,Landry T,Amar-Zifkin A,Ramanakumar AV,Martel MO,Baldini G,Feldman L,Fiore JF Jr

更新日期：2020-02-02 00:00:00

abstract：OBJECTIVE:To explore experts' views on factors influencing national and global active case-finding (ACF) policy development and implementation, and the use of evidence in these processes. DESIGN:This is an exploratory study based on semistructured expert interviews. Framework analysis was applied. PARTICIPANTS:The st...

journal_title：BMJ open

authors： Biermann O,Atkins S,Lönnroth K,Caws M,Viney K

更新日期：2020-06-03 00:00:00

abstract：INTRODUCTION:In acute pulmonary embolism (PE), poor outcome is usually related to right ventricular (RV) failure due to the increase in RV afterload. Treatment of PE with RV failure without shock is controversial and usually relies on fluid expansion to increase RV preload. However, several studies suggest that fluid e...

journal_title：BMJ open

authors： Gallet R,Meyer G,Ternacle J,Biendel C,Brunet A,Meneveau N,Rosario R,Couturaud F,Sebbane M,Lamblin N,Bouvaist H,Coste P,Maitre B,Bastuji-Garin S,Dubois-Rande JL,Lim P

更新日期：2015-05-22 00:00:00

abstract：OBJECTIVES:To determine the prevalence of depression among male and female medical students, its change over time and whether depression persists for affected students. DESIGN:Longitudinal study comprising annual questionnaire surveys which included the depression subscale of the Hospital Anxiety and Depression Scale ...

journal_title：BMJ open

authors： Quince TA,Wood DF,Parker RA,Benson J

更新日期：2012-08-13 00:00:00

abstract：INTRODUCTION:Reduction in low-density lipoprotein cholesterol (LDL-C) improves clinical outcomes in patients with coronary artery disease. However, rates of lipid-lowering medication adherence are far from ideal. Reducing dosage frequency from multiple dosing to once-daily dosing may improve patients' medication adhere...

journal_title：BMJ open

authors： Wu Z,Wu D,Jiang J,Chen A,Zheng DD,Li J,Dong Y,Chen Y

更新日期：2020-05-17 00:00:00

abstract：OBJECTIVE:To identify associations between the weight groups underweight (UW), overweight (OW) and obesity (OB) at 5 years of age and exposures related to pregnancy, anthropometric measures at birth, sociodemographic factors, and family health, anthropometric measures and habits. DESIGN:Regional cohort study. SETTING...

journal_title：BMJ open

authors： Donkor HM,Grundt JH,Júlíusson PB,Eide GE,Hurum J,Bjerknes R,Markestad T

更新日期：2017-08-18 00:00:00

abstract：INTRODUCTION:People with intellectual disability (ID) are more likely to experience loneliness and have smaller social networks, which increases vulnerability to depression. Befriending may reduce depressive symptoms in other populations, but randomised controlled trials (RCTs) have not been carried out in this populat...

journal_title：BMJ open

authors： Ali A,Mckenzie E,Hassiotis A,Priebe S,Lloyd-Evans B,Omar R,Jones R,Panca M,Fernandez V,Finning S,Moore S,O'Connor D,Roe C,King M

更新日期：2020-06-21 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate the factor structure of the Chinese version of the 22-item Zarit Burden Interview (ZBI) among family caregivers of patients with schizophrenia in China. METHODS:Using one-stage cluster-sampling design, 324 primary caregivers of patients with schizophrenia in Ningxiang County, Hun...

journal_title：BMJ open

authors： Tang B,Yu Y,Liu Z,Lin M,Chen Y,Zhao M,Xiao S

更新日期：2017-09-29 00:00:00

abstract：OBJECTIVE:Evidence-based performance measures have been increasingly used to evaluate hospital quality of stroke care, but their impact on stroke outcomes has not been verified. We aimed to evaluate the correlations between hospital performance measures and outcomes among patients with acute ischaemic stroke in a Chine...

journal_title：BMJ open

authors： Zhang X,Li Z,Zhao X,Xian Y,Liu L,Wang C,Wang C,Li H,Prvu Bettger J,Yang Q,Wang D,Jiang Y,Bao X,Yang X,Wang Y,Wang Y

更新日期：2018-08-01 00:00:00

abstract：INTRODUCTION:Rapid, robust and continually updated evidence synthesis is required to inform management of COVID-19 in pregnant and postpartum women and to keep pace with the emerging evidence during the pandemic. METHODS AND ANALYSIS:We plan to undertake a living systematic review to assess the prevalence, clinical ma...

journal_title：BMJ open

authors： Yap M,Debenham L,Kew T,Chatterjee SR,Allotey J,Stallings E,Coomar D,Lee SI,Qiu X,Yuan M,Clavé Llavall A,Dixit A,Zhou D,Balaji R,van Wely M,Kostova E,van Leeuwen E,Mofenson L,Kunst H,Khalil A,Tiberi S,Thomas J,

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:To assess whether a journal club model could improve comprehension and written and spoken medical English in a population of Chinese medical professionals. SETTING AND PARTICIPANTS:The study population consisted of 52 medical professionals who were residents or postgraduate master or PhD students in the Dep...

journal_title：BMJ open

authors： Tsui IK,Dodson WC,Kunselman AR,Kuang H,Han FJ,Legro RS,Wu XK

更新日期：2016-01-28 00:00:00

abstract：OBJECTIVE:To identify components of a proposed blood-borne virus (BBV) population screening programme and its associated consent procedure that both the public and health practitioners (HPs) would find acceptable. The proposed BBV screening system would aim to reduce late diagnosis of BBVs and be used in patients under...

journal_title：BMJ open

authors： Crane D,Henderson EJ,Chadwick DR

更新日期：2017-05-29 00:00:00

abstract：OBJECTIVE:Previous studies that have found an increased risk for tuberculosis (TB) in people with diabetes mellitus (DM) have been conducted in segments of the population and have not adjusted for important potential confounders. We sought to determine the RR for TB in the presence of DM in a national population with d...

journal_title：BMJ open

authors： Dobler CC,Flack JR,Marks GB

更新日期：2012-02-13 00:00:00

abstract：OBJECTIVE:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but serious side effect of bisphosphonates (BPs). Since this disease has no independent code in either of the diseases' or in the medical procedures' classifications, it is hard to estimate how many BP patients are affected. DESIGN:A retrospec...

journal_title：BMJ open

authors： Veszelyné Kotán E,Bartha-Lieb T,Parisek Z,Meskó A,Vaszilkó M,Hankó B

更新日期：2019-05-22 00:00:00

abstract：OBJECTIVES:Worldwide, the Irish diaspora experience elevated mortality and morbidity across generations, not accounted for through socioeconomic position. The main objective of the present study was to assess if childhood disadvantage accounts for poorer mental and physical health in adulthood, in second-generation Iri...

journal_title：BMJ open

authors： Das-Munshi J,Clark C,Dewey ME,Leavey G,Stansfeld SA,Prince MJ

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Little is known about the applicability of mindfulness-based interventions in Spanish adults with overweight/obesity. The objective of the present study protocol is to describe the methods that will be used in a cluster randomised trial (CRT) that aims to evaluate the effectiveness of a mindfulness eating ...

journal_title：BMJ open

authors： Morillo Sarto H,Barcelo-Soler A,Herrera-Mercadal P,Pantilie B,Navarro-Gil M,Garcia-Campayo J,Montero-Marin J

更新日期：2019-11-21 00:00:00

abstract：INTRODUCTION:Cyclooxygenase 2 (COX-2) inhibitors have less upper gastrointestinal toxicity than traditional non-steroidal anti-inflammatory drugs (NSAIDs). However, both COX-2 inhibitors and traditional NSAIDs may be associated with adverse cardiovascular side effects. Data from randomised and observational studies sug...

journal_title：BMJ open

authors： Macdonald TM,Mackenzie IS,Wei L,Hawkey CJ,Ford I,SCOT study group collaborators.

更新日期：2013-01-29 00:00:00

abstract：INTRODUCTION:Developmental alterations to the circadian rhythm, in combination with lifestyle changes (eg, changes in school start time, part-time employment), contribute to insufficient sleep among youth. Insufficient sleep is associated with poor eating behaviours in other developmental stages (ie, childhood, adultho...

journal_title：BMJ open

authors： Doan N,Ferro MA

更新日期：2019-12-11 00:00:00

abstract：INTRODUCTION:Financial toxicity (FT) is a well-recognised problem in oncology. US-based studies have shown that: (a) cancer patients have a 2.7 times risk of bankruptcy; (b) patients who declare bankruptcy have a 79% greater hazard of death; (c) financial burden significantly impairs quality of life (QoL) and (d) reduc...

journal_title：BMJ open

authors： Riva S,Bryce J,De Lorenzo F,Del Campo L,Di Maio M,Efficace F,Frontini L,Giannarelli D,Gitto L,Iannelli E,Jommi C,Montesarchio V,Traclò F,Vaccaro CM,Gallo C,Perrone F

更新日期：2019-09-09 00:00:00

abstract：OBJECTIVES:To describe the clinical profile of Brazilian patients with type 2 diabetes attending the public healthcare system and identify factors associated with poor glycaemic control. DESIGN:Cross-sectional study. SETTING:14 centres in five regions of Brazil, including primary care units and outpatient clinics of ...

journal_title：BMJ open

authors： Viana LV,Leitão CB,Kramer CK,Zucatti AT,Jezini DL,Felício J,Valverde AB,Chacra AR,Azevedo MJ,Gross JL

更新日期：2013-09-18 00:00:00