Coexistence of diffuse panbronchiolitis and sarcoidosis revealed during splenectomy: a case report.

abstract：BACKGROUND:This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II) cells after exposure to hyperoxia. METHODS:pcDNA3.1(+)-C/EBPα plasmid or air-empty vector were tr...

journal_title：BMC pulmonary medicine

authors： Lu H,Chen X,Lu Y,Zhu H,Tang W,Wang Q

更新日期：2019-08-06 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-environment interactions associated with tobacco smoking (COPD-TS) and biomass smoke (COPD-BS). It is w...

journal_title：BMC pulmonary medicine

authors： Velasco-Torres Y,Ruiz-López V,Pérez-Bautista O,Buendía-Roldan I,Ramírez-Venegas A,Pérez-Ramos J,Falfán-Valencia R,Ramos C,Montaño M

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:It has been recognized that despite previous stability some patients with idiopathic pulmonary fibrosis (IPF) experience acute clinical deteriorations called acute exacerbations of idiopathic pulmonary fibrosis (AEX-IPF). We hypothesized that pulmonary infection can be excluded based on clinical and laborato...

journal_title：BMC pulmonary medicine

authors： Petrosyan F,Culver DA,Reddy AJ

更新日期：2015-07-10 00:00:00

abstract：BACKGROUND:Influenza is a frequent cause of exacerbations of chronic obstructive pulmonary disease (COPD). Exacerbations are associated with worsening of the airflow obstruction, hospitalisation, reduced quality of life, disease progression, death, and ultimately, substantial healthcare-related costs. Despite longstand...

journal_title：BMC pulmonary medicine

authors： Bekkat-Berkani R,Wilkinson T,Buchy P,Dos Santos G,Stefanidis D,Devaster JM,Meyer N

更新日期：2017-05-03 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:To investigate the use of do-not-resuscitate (DNR) orders in patients hospitalized with community-acquired pneumonia (CAP) and the association with mortality. METHODS:We assembled a cohort of 1317 adults hospitalized with radiographically confirmed CAP in three Danish hospitals. Patients were grouped into n...

journal_title：BMC pulmonary medicine

authors： Egelund GB,Jensen AV,Petersen PT,Andersen SB,Lindhardt BØ,Rohde G,Ravn P,von Plessen C

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:ALK-rearrangement is observed in < 5% non-small cell lung cancer (NSCLC) cases and prior to the advent of oral tyrosine kinase inhibitors, the natural history of oncogenic NSCLC was typically poor. Literature relating to regression of treatment-naïve NSCLC is limited, and regression without treatment has not...

journal_title：BMC pulmonary medicine

authors： Walls M,Walls GM,James JA,Crawford KT,Abdulkhalek H,Lynch TB,Peace AJ,McManus TE,Evans OR

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:The Global Lung Function Initiative 2012 (GLI) reference values are currently endorsed by several respiratory societies but evaluations of applicability for adults resident in European countries are lacking. The aim of this study was to evaluate if the GLI reference values are appropriate for an adult Caucas...

journal_title：BMC pulmonary medicine

authors： Backman H,Lindberg A,Sovijärvi A,Larsson K,Lundbäck B,Rönmark E

更新日期：2015-03-25 00:00:00

abstract：BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...

journal_title：BMC pulmonary medicine

authors： Zhang HL,Tan M,Qiu AM,Tao Z,Wang CH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:There is emerging evidence regarding the efficacy of exercise training to improve exercise capacity for individuals with non-small cell lung cancer (NSCLC). Cardiopulmonary exercise testing (CPET) is the gold standard measure of exercise capacity; however this laboratory test has limitations for use in resea...

journal_title：BMC pulmonary medicine

authors： Granger CL,Denehy L,Parry SM,Martin J,Dimitriadis T,Sorohan M,Irving L

更新日期：2015-08-12 00:00:00

abstract：BACKGROUND:Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little is known about characteristics that predict onset of resting hypoxemia in patients who are normoxic...

journal_title：BMC pulmonary medicine

authors： Wells JM,Estepar RS,McDonald MN,Bhatt SP,Diaz AA,Bailey WC,Jacobson FL,Dransfield MT,Washko GR,Make BJ,Casaburi R,van Beek EJ,Hoffman EA,Sciurba FC,Crapo JD,Silverman EK,Hersh CP,COPDGene Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The long-term prognosis of chronic cough and its determinants need to be clarified. METHODS:This is a prospective, observational cohort study. Eighty-nine unselected subjects with chronic (> 8 weeks' duration) cough were carefully investigated: Clinical examination, symptom questionnaire, Leicester Cough Qu...

journal_title：BMC pulmonary medicine

authors： Koskela HO,Lätti AM,Purokivi MK

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Spontaneous pneumothorax is a common problem globally. Bullas and blebs have been implicated in this problem, but the etiology of their formation is unknown. We aim to show the relation between a novel clinical finding, the pulmonary delayed inflation (PDI) sign, and the etiology of bulla and bleb formation ...

journal_title：BMC pulmonary medicine

authors： Iyoda A,Azuma Y,Sakai T,Koezuka S,Otsuka H,Sano A

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic int...

journal_title：BMC pulmonary medicine

authors： Morris PE,Steingrub JS,Huang BY,Tang S,Liu PM,Rhode PR,Wong HC

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS:E...

journal_title：BMC pulmonary medicine

authors： Matsson H,Söderhäll C,Einarsdottir E,Lamontagne M,Gudmundsson S,Backman H,Lindberg A,Rönmark E,Kere J,Sin D,Postma DS,Bossé Y,Lundbäck B,Klar J

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:Idiopathic Pulmonary Fibrosis (IPF) is a fatal fibrotic lung disease occurring predominantly in middle-aged and older adults. The traditional diagnostic classification of IPF is based on clinical, radiological, and histopathological features. However, the considerable heterogeneity in IPF presentation sugges...

journal_title：BMC pulmonary medicine

authors： Wang Y,Yella J,Chen J,McCormack FX,Madala SK,Jegga AG

更新日期：2017-10-20 00:00:00

abstract：BACKGROUND:Although patients have more problems using metered dose inhalers, clinical comparisons suggest they provide similar control to dry powder inhalers. Using real-life situations this study was designed to evaluate asthma control in outpatients with moderate to severe persistent asthma and to compare efficacy of...

journal_title：BMC pulmonary medicine

authors： Müller V,Gálffy G,Eszes N,Losonczy G,Bizzi A,Nicolini G,Chrystyn H,Tamási L

更新日期：2011-07-15 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominantly the upper lobes. PPFE may occur in different contextes like bone marrow or lung transplantations,...

journal_title：BMC pulmonary medicine

authors： Hassoun D,Dirou S,Arrigoni PP,Durant C,Hamidou M,Néel A,Agard C

更新日期：2018-05-18 00:00:00

abstract：BACKGROUND:IL-4 and IL-13 play a critical yet poorly understood role in orchestrating the recruitment and activation of effector cells of the asthmatic response and driving the pathophysiology of allergic asthma. The house dust mite (HDM) sheep asthma model displays many features of the human condition and is an ideal ...

journal_title：BMC pulmonary medicine

authors： Liravi B,Piedrafita D,Nguyen G,Bischof RJ

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a form of chronic fibrosing interstitial pneumonia characterized by progressive worsening of dyspnea and lung function, with a poor prognosis. The objective of this study was to determine treatment patterns, resource use and costs of managing Spanish patients with IPF. ...

journal_title：BMC pulmonary medicine

authors： Morell F,Esser D,Lim J,Stowasser S,Villacampa A,Nieves D,Brosa M

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:A recent method determines regional gas flow of the lung by electrical impedance tomography (EIT). The aim of this study is to show the applicability of this method in a porcine model of mechanical ventilation in healthy and diseased lungs. Our primary hypothesis is that global gas flow measured by EIT can b...

journal_title：BMC pulmonary medicine

authors： Bodenstein M,Boehme S,Bierschock S,Vogt A,David M,Markstaller K

更新日期：2014-04-29 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. ...

journal_title：BMC pulmonary medicine

authors： Holmgaard DB,Mygind LH,Titlestad IL,Madsen H,Pedersen SS,Johansen JS,Pedersen C

更新日期：2013-12-30 00:00:00

abstract：BACKGROUND:We have previously shown that diabetic rats are more susceptible to sepsis, but that the Acute lung injury (ALI) secondary to sepsis is less intense than in non-diabetics. In the present study, we further investigated the ALI-secondary to sepsis in diabetic rats and the effect of insulin treatment. METHODS:...

journal_title：BMC pulmonary medicine

authors： Filgueiras LR,Capelozzi VL,Martins JO,Jancar S

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Diagnostic tools, including culture, serologic test and PCR-based methods, are available but prone to false negative results. CASE PRESENTATION:This report included five cases of Chlamydia psittaci pneumonia. Symptom...

journal_title：BMC pulmonary medicine

authors： Gu L,Liu W,Ru M,Lin J,Yu G,Ye J,Zhu ZA,Liu Y,Chen J,Lai G,Wen W

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Exacerbations, a leading cause of hospitalization in patients with chronic obstructive pulmonary disease (COPD), affect the quality of life and prognosis. Treatment recommendations as provided in the evidence-based guidelines are not consistently followed, partly due to absence of simplified task-oriented ap...

journal_title：BMC pulmonary medicine

authors： Ban A,Ismail A,Harun R,Abdul Rahman A,Sulung S,Syed Mohamed A

更新日期：2012-06-22 00:00:00

abstract：:Following publication of the original article [1], the author flagged aspects of the article that affected readability of some of the article's scientific content. ...

journal_title：BMC pulmonary medicine

authors： Fuchs O,Bahmer T,Weckmann M,Dittrich AM,Schaub B,Rösler B,Happle C,Brinkmann F,Ricklefs I,König IR,Watz H,Rabe KF,Kopp MV,Hansen G,von Mutius E,ALLIANCE Study Group as part of the German Centre for Lung Research (DZL).

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:The most prevalent complication of percutaneous lung biopsy is pneumothorax (PNX). A routine immediate post-procedure CT scan (ICT) to spot PNX is done in many centers. However, the diagnostic yield of this practice has not been studied broadly. We sought to evaluate whether an ICT could replace the routine ...

journal_title：BMC pulmonary medicine

authors： Brzezinski RY,Vigiser I,Fomin I,Israeli L,Shenhar-Tsarfaty S,Bar-Shai A

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is combination of progressive lung diseases. The diagnosis of COPD is generally based on the pulmonary function testing, however, difficulties underlie in prognosis of smokers or early stage of COPD patients due to the complexity and heterogeneity of the pathogene...

journal_title：BMC pulmonary medicine

authors： Matsumura K,Ito S

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of ...

journal_title：BMC pulmonary medicine

authors： Kamata H,Asakura T,Suzuki S,Namkoong H,Yagi K,Funatsu Y,Okamori S,Uno S,Uwamino Y,Fujiwara H,Nishimura T,Ishii M,Betsuyaku T,Hasegawa N

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS...

journal_title：BMC pulmonary medicine

authors： Nguyen HQ,Herting JR,Pike KC,Gharib SA,Matute-Bello G,Borson S,Kohen R,Adams SG,Fan VS

更新日期：2016-12-03 00:00:00