Abstract:
BACKGROUND:Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Diagnostic tools, including culture, serologic test and PCR-based methods, are available but prone to false negative results. CASE PRESENTATION:This report included five cases of Chlamydia psittaci pneumonia. Symptoms and signs common to all 5 cases included fever, coughing, generalized muscle ache, and most notably, inflammatory infiltration of the lungs upon chest CT and X-ray. Metagenomic next-generation sequencing (mNGS) revealed the presence of Chlamydia psittaci in biopsy lung tissue in 3 cases and bronchoalveolar lavage fluid in the remaining 2 cases. Three patients responded to doxycycline plus moxifloxacin; two patients responded to moxifloxacin alone. CONCLUSIONS:mNGS could be used to diagnose Chlamydia psittaci pneumonia.
journal_name
BMC Pulm Medjournal_title
BMC pulmonary medicineauthors
Gu L,Liu W,Ru M,Lin J,Yu G,Ye J,Zhu ZA,Liu Y,Chen J,Lai G,Wen Wdoi
10.1186/s12890-020-1098-xsubject
Has Abstractpub_date
2020-03-17 00:00:00pages
65issue
1issn
1471-2466pii
10.1186/s12890-020-1098-xjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:Very few data exist on the management of community-acquired pneumonia (CAP) in patients admitted to hospitals in the Gulf region. The objectives of this study were to describe treatment patterns for CAP in 38 hospitals in five Gulf countries (United Arab Emirates, Kuwait, Bahrain, Oman, and Qatar) and to com...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-015-0108-x
更新日期:2015-09-30 00:00:00
abstract:BACKGROUND:Systemic inflammation plays an important role in the initiation, promotion, and progression of lung carcinogenesis. In patients with non-small cell lung cancer (NSCLC), fibrinogen levels correlate with neoplasia. Here we compared the effects of pulmonary rehabilitation (PR) with chest physical therapy (CPT) ...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2466-14-121
更新日期:2014-07-28 00:00:00
abstract:BACKGROUND:The pathological appearance of idiopathic pleuroparenchymal fibroelastosis (IPPFE) with hematoxylin-eosin staining is similar to that of usual interstitial pneumonia (UIP) in patients with idiopathic pulmonary fibrosis (IPF). The amount of elastic fibers (EF) and detailed differences between IPPFE and IPF ha...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-91
更新日期:2014-05-28 00:00:00
abstract:BACKGROUND:Aspergillus fumigatus is frequently encountered in sputum samples of patients with cystic fibrosis (CF), which traditionally has been interpreted as saprophytic airway colonization. However, this mere bystander role has been challenged by recent data. There is now evidence that Aspergillus fumigatus accelera...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0614-8
更新日期:2018-03-27 00:00:00
abstract:BACKGROUND:Pulsus paradoxus estimated by dynamic change in area under the oximeter plethysmograph waveform (PEP) might provide a measure of acute asthma severity. Our primary objective was to determine how well PEP correlates with forced expiratory volume in 1-second (%FEV1) (criterion validity) and change of %FEV1 (re...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-10-17
更新日期:2010-03-29 00:00:00
abstract:BACKGROUND:Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been identified as the microbial volatile organic compound 2-aminoacetophenone (2-AA). METHODS:We investig...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-10-56
更新日期:2010-11-07 00:00:00
abstract:BACKGROUND:Little is known about whether or how supplemental oxygen affects patients with pulmonary fibrosis. METHODS/DESIGN:A mixed-methods study is described. Patients with pulmonary fibrosis, informal caregivers of pulmonary fibrosis patients and practitioners who prescribe supplemental oxygen will be interviewed t...
journal_title:BMC pulmonary medicine
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2466-14-169
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of reactive oxygen species (ROS), oxidative stress is a mechanistically imperative factor in asthma. Ast...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-122
更新日期:2014-07-29 00:00:00
abstract:BACKGROUND:Anti-tuberculosis therapy requires at least six-month treatment with continuous administration of combined antibiotics, including isoniazid, rifampicin, pyrazinamide, and ethambutol. The long-term exposure to antibiotics could cause consequent changes in gut microbiota, which may alter the gastrointestinal f...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
doi:10.1186/s12890-019-0981-9
更新日期:2019-11-11 00:00:00
abstract:BACKGROUND:Many studies have investigated whether pleural cholesterol levels can aid in diagnosis of pleural exudates, and the results have varied considerably. To gain a more reliable answer to this question, we meta-analyzed the literature on using pleural cholesterol or the ratio of cholesterol in pleural fluid to c...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1471-2466-14-61
更新日期:2014-04-15 00:00:00
abstract:BACKGROUND:Diagnosis of lower respiratory tract infections (LRTI) depends on the presence of clinical, radiological and microbiological findings. Endotracheal suction aspirate (ETSA) is the commonest respiratory sample sent for culture from intubated patients. Very few studies have compared quantitative and semi-quanti...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-01311-7
更新日期:2020-10-29 00:00:00
abstract:BACKGROUND:The Darlington and Northallerton Asthma Study is an observational cohort study started in 1983. At that time little was published about long term outcome in asthma and the contribution of change in reversible disease or airway remodelling to any excess deterioration in function. The study design included reg...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-5-2
更新日期:2005-01-31 00:00:00
abstract:BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-1079-0
更新日期:2020-02-13 00:00:00
abstract:BACKGROUND:It is widely recognized that health-related quality of life (HRQL) is impaired in patients with Chronic Obstructive Pulmonary Disease (COPD), but there is a lack of research on longitudinal associations of COPD and HRQL. This study examined the effects of COPD in early stages of disease on HRQL over ten year...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-134
更新日期:2014-08-09 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to identify the factors associated with carbon dioxide retention. METHODS:This was a retrospective study of...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0691-8
更新日期:2018-07-31 00:00:00
abstract:BACKGROUND:Lower respiratory tract infection (LRIs) is very common both in terms of community-acquired infection and hospital-acquired infection. Sputum and bronchoalveolar lavage fluid (BALF) are the most important specimens obtained from patients with LRI. The choice of antibiotic with which to treat LRI usually depe...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-01275-8
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Noninvasive ventilation (NIV) is used in critically ill patients with acute respiratory failure (ARF) to avoid endotracheal intubation. However, the impact of NIV use on ARF patient's outcomes is still unclear. Our objectives were to evaluate the rate of NIV failure in hypoxemic patients with an arterial car...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-015-0139-3
更新日期:2015-11-11 00:00:00
abstract:BACKGROUND:Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients would have reduced bronchoalveolar lavage (BAL) fluid SP-D levels compared to healthy smoking and no...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-10-53
更新日期:2010-10-25 00:00:00
abstract:BACKGROUND:The early diagnosis of non-small cell lung cancer is of great significance to the prognosis of patients. However, traditional histopathology and imaging screening have certain limitations. Therefore, new diagnostical methods are urgently needed for the current clinical diagnosis. In this study we evaluated t...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-01314-4
更新日期:2020-10-20 00:00:00
abstract:BACKGROUND:The collection of exhaled breath condensate (EBC) is a suitable and non-invasive method for evaluation of airway inflammation. Several studies indicate that the composition of the condensate and the recovery of biomarkers are affected by physical characteristics of the condensing device and collecting circum...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-9-48
更新日期:2009-11-30 00:00:00
abstract:BACKGROUND:A variety of large randomized controlled trials (RCT's) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-acting anticholinergic glycopyrronium bromide. METHODS:As the generalizability of results from RCT's i...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1471-2466-15-2
更新日期:2015-01-12 00:00:00
abstract:BACKGROUND:Although many studies on people with Chronic Obstructive Pulmonary Disease (COPD) have examined the mutual impact of physical status and emotional experience, there is limited knowledge about the way COPD people first-hand perceive their condition. This study was designed to investigate the illness perceptio...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-1157-3
更新日期:2020-05-04 00:00:00
abstract:BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2466-14-125
更新日期:2014-08-04 00:00:00
abstract:BACKGROUND:Recurrent airway infections are common in patients with Down's syndrome (DS). Hence, ruling out Cystic Fibrosis (CF) in these patients is often required. In the past, the value of sweat testing - the gold standard to diagnose CF - has been questioned in DS as false positive results have been reported. Howeve...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0580-1
更新日期:2018-01-16 00:00:00
abstract:BACKGROUND:Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains unclear. Current guidelines recommend treating beyond 4 cycles -up to 6-, in patients that respond to an...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
doi:10.1186/s12890-019-0948-x
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Pulmonary rehabilitation offers potential benefits to people with asthma. It is however unknown if rehabilitation favourably affects patients' health care needs. We therefore examined if rehabilitation reduced needs and, in addition, if it improved asthma control. METHODS:One hundred fifty patients with ast...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-01301-9
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD) from day-to-day symptom variations would be an important development in clinical practice and research. We assessed the ability of domiciliary pulse oximetry to achieve this. METHODS:40 patients with moder...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-10-52
更新日期:2010-10-20 00:00:00
abstract:BACKGROUND:Asthma is a chronic inflammatory airway disease characterized by reversible obstruction, inflammation and hyperresponsiveness to different stimulus. Aerobic and breathing exercises have been demonstrated to benefit asthmatic patients; however, there is no evidence comparing the effectiveness of these treatme...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2466-14-160
更新日期:2014-10-17 00:00:00
abstract:BACKGROUND:Exposure to perinatal anxiety affects disease susceptibility in offspring but studies on the association between perinatal anxiety and gene polymorphisms are lacking. This study aimed to elucidate the interaction between perinatal anxiety and polymorphisms in antioxidant defense and innate immunity genes on ...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-154
更新日期:2014-09-29 00:00:00
abstract:BACKGROUND:The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and the Medical Outcomes Study Short Form 36 (SF-36) are widely used to assess patient-reported outcome in individuals with pulmonary hypertension (PH). The aim of the study was to compare the psychometric properties of the two measures. METHODS:...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2466-13-45
更新日期:2013-07-12 00:00:00