An observational study of patho-oncological outcomes of various surgical methods in total mesorectal excision for rectal cancer: a single center analysis.

Abstract:

BACKGROUND:Total mesorectal excision (TME) with or without neoadjuvant concurrent chemoradiotherapy (CCRT) is the treatment for rectal cancer (RC). Recently, the use of conventional laparoscopic surgery (LS) or robotic-assisted surgery (RS) has been on a steady increase cases. However, various oncological outcomes from different surgical approaches are still under investigation. METHODS:This is a retrospective observational study comprising 300 consecutive RC patients who underwent various techniques of TME (RS, n = 88; LS, n = 37; Open surgery, n = 175) at a single center of real world data to compare the pathological and oncological outcomes, with a median follow-up of 48 months. RESULTS:Upon multivariate analysis, histologic grade (P = 0.016), and stage (P < 0.001) were the independent factors of circumferential resection margin (CRM) involvement. The Kaplan-Meier survival analysis determined RS, early pathologic stage, negative CRM involvement, and pathologic complete response to be significantly associated with better overall survival (OS) and disease-free survival (DFS) (all P < 0.05). Multivariable analyses observed the surgical method (P = 0.037), histologic grade (P = 0.006), and CRM involvement (P = 0.043) were the independent factors of DFS, whereas histologic grade (P = 0.011) and pathologic stage (P = 0.022) were the independent prognostic variables of OS. CONCLUSIONS:This study determined that RS TME is feasible because it has less CRM involvement and better oncological outcomes than the alternatives have. The significant factors influencing CRM and prognosis depended on the histologic grade, tumor depth, and pre-operative CCRT. RS might be an acceptable option owing to the favorable oncological outcomes for patients with RC undergoing TME.

journal_name

BMC Surg

journal_title

BMC surgery

authors

Chen YT,Huang CW,Ma CJ,Tsai HL,Yeh YS,Su WC,Chai CY,Wang JY

doi

10.1186/s12893-020-0687-1

subject

Has Abstract

pub_date

2020-02-03 00:00:00

pages

23

issue

1

issn

1471-2482

pii

10.1186/s12893-020-0687-1

journal_volume

20

pub_type

杂志文章
  • Sphincter saving anorectoplasty (SSARP) for the reconstruction of Anorectal malformations.

    abstract:BACKGROUND:This report describes a new technique of sphincter saving anorectoplasty (SSARP) for the repair of anorectal malformations (ARM). METHODS:Twenty six males with high ARM were treated with SSARP. Preoperative localization of the center of the muscle complex is facilitated using real time sonography and comput...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-7-20

    authors: Pratap A,Tiwari A,Kumar A,Adhikary S,Singh SN,Paudel BH,Bartaula R,Mishra B

    更新日期:2007-09-24 00:00:00

  • Comparison of single posterior debridement, bone grafting and instrumentation with single-stage anterior debridement, bone grafting and posterior instrumentation in the treatment of thoracic and thoracolumbar spinal tuberculosis.

    abstract:BACKGROUND:To compare the clinical efficacy of single posterior debridement, bone grafting and instrumentation with that of single-stage anterior debridement, bone grafting and posterior instrumentation for treatment of adult patients with thoracic and thoracolumbar spinal tuberculosis (TB). METHODS:We performed a ret...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-018-0405-4

    authors: Zhou Y,Li W,Liu J,Gong L,Luo J

    更新日期:2018-09-03 00:00:00

  • Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol.

    abstract:BACKGROUND:Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-2-2

    authors: Bachmann LM,Bischof DB,Bischofberger SA,Bonani MG,Osann FM,Steurer J

    更新日期:2002-04-10 00:00:00

  • The utility of the hematoxylin and eosin staining in patients with suspected Hirschsprung disease.

    abstract:BACKGROUND:While immunohistochemistry (IHC) methods have been widely conducted for the diagnosis of Hirschsprung disease (HSCR) in developed countries, there are very few studies on their use in developing countries where hematoxylin and eosin (HE) staining is a key element of the diagnosis of HSCR. We aimed to determi...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-017-0267-1

    authors: Setiadi JA,Dwihantoro A,Iskandar K,Heriyanto DS,Gunadi

    更新日期:2017-06-19 00:00:00

  • Peroneal artery pseudoaneurysm--a case report and literature review.

    abstract:BACKGROUND:Aneurysms of the peroneal artery are infrequent and consist mainly of pseudoaneurysms. CASE PRESENTATION:This report describes an unusual case of peroneal pseudoaneurysm developing after thromoboembolectomy with a Fogarty catheter. It was managed successfully using an endovascular technique consisting of se...

    journal_title:BMC surgery

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2482-7-4

    authors: Sadat U,See T,Cousins C,Hayes P,Gaunt M

    更新日期:2007-03-29 00:00:00

  • Advantage of laparoscopy surgery for elderly colorectal cancer patients without compromising oncologic outcome.

    abstract:BACKGROUND:Laparoscopic surgery has achieved significant results in elderly patients with colorectal cancer (CRC). In this study, we compared the short-term and long-term outcomes of open surgery and laparoscopic surgery in patients with CRC aged above 75 years at a single tertiary medical center. METHODS:We analyzed ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-00967-6

    authors: Chern YJ,Hung HY,You JF,Hsu YJ,Chiang JM,Hsieh PS,Tsai WS

    更新日期:2020-11-23 00:00:00

  • VFMSS findings in elderly dysphagic patients: our experience.

    abstract:BACKGROUND:Dysphagia consists in alteration of the swallowing mechanism, due to different pathological conditions, which can occur at different levels. The exact prevalence of dysphagia is unclear, even if some AA suggest that 15% of the elderly population is affected. Aim of this study is to analyze the main VFMSS fin...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-13-S2-S54

    authors: Reginelli A,Iacobellis F,Del Vecchio L,Monaco L,Berritto D,Di Grezia G,Genovese E,Giganti M,Cappabianca S

    更新日期:2013-01-01 00:00:00

  • Pancreas-visceral fat CT value ratio and serrated pancreatic contour are strong predictors of postoperative pancreatic fistula after pancreaticojejunostomy.

    abstract:BACKGROUND:Our aim is to elucidate the true preoperative risk factors for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD), making it possible to select POPF high-risk patients preoperatively regardless of intraoperative pancreatic consistency judged by the surgeon's hand. METHODS:Among the 2...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-00785-w

    authors: Kusafuka T,Kato H,Iizawa Y,Noguchi D,Gyoten K,Hayasaki A,Fujii T,Murata Y,Tanemura A,Kuriyama N,Azumi Y,Kishiwada M,Mizuno S,Usui M,Sakurai H,Isaji S

    更新日期:2020-06-11 00:00:00

  • Mucinous cystic neoplasm of the liver with biliary communication: case report and surgical therapeutic option.

    abstract:BACKGROUND:Mucinous cyst neoplasm of the liver (MCN-L) comprise less than 5% of all cystic liver lesions and is characterized by the presence of ovarian stroma and absence of bile duct communication. CASE PRESENTATION:Here, we discuss a 45-year-old woman who presented with symptomatic liver mass. Diagnostic workup det...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-01003-3

    authors: Ferreira R,Abreu P,Jeismann VB,Segatelli V,Coelho FF,David AI

    更新日期:2020-12-11 00:00:00

  • Total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation as the treatment of choice for secondary hyperparathyroidism: a single-center experience.

    abstract:BACKGROUND:The aim of the study was to evaluate total parathyroidectomy with trace amounts of parathyroid tissue (30 mg) as a surgical option in secondary hyperparathyroidism (sHPT) treatment. METHODS:From January 2008 to March 2012, 47 patients underwent parathyroidectomy. Comparisons of demographic data, symptoms, a...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-14-26

    authors: He Q,Zhuang D,Zheng L,Fan Z,Zhou P,Zhu J,Duan S,Li Y,Ge Y,Lv Z,Cao L

    更新日期:2014-05-05 00:00:00

  • Laryngocele: a rare complication of surgical tracheostomy.

    abstract:BACKGROUND:A laryngocele is usually a cystic dilatation of the laryngeal saccule. The etiology behind its occurrence is still unclear, but congenital and acquired factors have been implicated in its development. CASE PRESENTATION:We present a rare case of laryngocele occurring in a 77-year-old Caucasian woman. The pat...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-6-14

    authors: Upile T,Jerjes W,Sipaul F,El Maaytah M,Singh S,Howard D,Hopper C,Wright A

    更新日期:2006-11-27 00:00:00

  • Clinical pictures mimicking acute hernia complications: are we really daring to violate a traditional abdominal wall surgery dogma?

    abstract:BACKGROUND:Acute abdominal wall hernia complications usually require a prompt surgical treatment. The aim of this case series is to report our experience with some unusual cases of apparent acute and subacute hernia complications not requiring surgical treatment, changing the classical paradigm of immediate surgical ap...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-00899-1

    authors: Zanatta M,Brancato G,Basile G,Basile F,Donati M

    更新日期:2020-10-15 00:00:00

  • Cervical lymph node metastasis classified as regional nodal staging in thoracic esophageal squamous cell carcinoma after radical esophagectomy and three-field lymph node dissection.

    abstract:BACKGROUND:Lymph node metastasis (LNM) is most common in esophageal squamous cell carcinoma (SCC). The bi-directional spread is a key feature of LNM in patients with thoracic esophageal SCC (TE-SCC). The purpose of this study was to analyze the prognostic factors of survival in patients with TE-SCC with cervical lymph ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-14-110

    authors: Chen J,Wu S,Zheng X,Pan J,Zhu K,Chen Y,Li J,Liao L,Lin Y,Liao Z

    更新日期:2014-12-19 00:00:00

  • Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-audit.

    abstract:BACKGROUND:One of the potential benefits of surgical audit is improved hospital cost-efficiencies arising from lower resource consumption associated with fewer adverse events. The aim of this study was to estimate the potential cost-savings for Australian hospitals from improved surgical performance for colorectal surg...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-10-4

    authors: Gordon LG,Obermair A

    更新日期:2010-01-27 00:00:00

  • Internal sphincterotomy reduces postoperative pain after Milligan Morgan haemorrhoidectomy.

    abstract:BACKGROUND:Over the last few years, there has been increasing attention on surgical procedures to treat haemorrhoids. The Milligan-Morgan haemorrhoidectomy is still one of the most popular surgical treatments of haemorrhoids. The aim of the present work is to assess postoperative pain, together with other early and lat...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-9-16

    authors: Diana G,Guercio G,Cudia B,Ricotta C

    更新日期:2009-10-24 00:00:00

  • Oncological and functional results after surgical treatment of bone metastases at the proximal femur.

    abstract:BACKGROUND:Metastatic lesions to the proximal femur occur frequently (about 10% of patients with cancer) and require surgical treatment. There are many surgical methods of treatment, however, use of the tumor modular endoprostheses seems to be particularly promising. The aim of study was to evaluate oncological and fun...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-018-0336-0

    authors: Guzik G

    更新日期:2018-01-25 00:00:00

  • A bilateral neoplasm in chest: a case report and literature review.

    abstract:BACKGROUND:Myelolipoma is a rare neoplasm composed of yellowish adipose tissue and reddish-brown tissue corresponding to hematopoietic or hemorrhages. It typically occurs in adrenal glands as a solitary, well-circumscribed mass, and the thoracic location is extremely unusual. CASE PRESENTATION:We present a rare case w...

    journal_title:BMC surgery

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2482-14-42

    authors: Shen C,Han Z,Che G

    更新日期:2014-07-09 00:00:00

  • Prediction of conversion of laparoscopic cholecystectomy to open surgery with artificial neural networks.

    abstract:BACKGROUND:The intent of this study was to predict conversion of laparoscopic cholecystectomy (LC) to open surgery employing artificial neural networks (ANN). METHODS:The retrospective data of 793 patients who underwent LC in a teaching university hospital from 1997 to 2004 was collected. We employed linear discrimina...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-9-13

    authors: Gholipour C,Fakhree MB,Shalchi RA,Abbasi M

    更新日期:2009-08-21 00:00:00

  • Comparison of the 3D-printed operation guide template technique and the free-hand technique for S2-alar-iliac screw placement.

    abstract:BACKGROUND:To compare the safety and accuracy of the 3D-printed operation guide template technique and the free-hand technique in the placement of the S2-alar-iliac (S2AI) screw. METHODS:We conducted a retrospective analysis of 47 patients undergoing S2AI screw placement in our hospital, divided into the 3D-printed op...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-00930-5

    authors: Zhao Y,Ma Y,Liang J,Luo H,Cai X,Xu Y,Lu S

    更新日期:2020-10-29 00:00:00

  • Proteinuria can predict prognosis after liver transplantation.

    abstract:BACKGROUND:Proteinuria is a manifestation of renal dysfunction and it has been demonstrated to be a significant prognostic factor in various clinical situations. The study was designed to analyze prognosis of patients receiving liver transplantation as well as to determine predictive performance of perioperative protei...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-016-0176-8

    authors: Pan HC,Chen YJ,Lin JP,Tsai MJ,Jenq CC,Lee WC,Tsai MH,Fan PC,Chang CH,Chang MY,Tian YC,Hung CC,Fang JT,Yang CW,Chen YC

    更新日期:2016-09-15 00:00:00

  • Kimura's disease mimicking thoracic spine dumbbell neurogenic tumor: a case report and literature review.

    abstract:BACKGROUND:Kimura's disease is a rare, benign chronic inflammatory disease of unknown etiology that mostly affects Asians. The disease typically presents as subcutaneous masses in the head or neck region that are predominantly found in the preauricular and submandibular areas. CASE PRESENTATION:A 7-year-old boy presen...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-00870-0

    authors: Bi S,Gu J,Hu C

    更新日期:2020-09-21 00:00:00

  • Mesh Or Patch for Hernia on Epigastric and Umbilical Sites (MORPHEUS trial): study protocol for a multi-centre patient blinded randomized controlled trial.

    abstract:BACKGROUND:Evidence is accumulating that, similar to other ventral hernias, umbilical and epigastric hernias must be mesh repaired. The difficulties involved in mesh placement and in mesh-related complications could be the reason many small abdominal hernias are still primary closed. In laparoscopic repair, a mesh is p...

    journal_title:BMC surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2482-14-33

    authors: Ponten JE,Leenders BJ,Charbon JA,Lettinga-van de Poll T,Heemskerk J,Martijnse IS,Konsten JL,Nienhuijs SW

    更新日期:2014-05-22 00:00:00

  • Hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy: HARP-trial.

    abstract:BACKGROUND:Transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Live donor nephrectomy is performed on healthy individuals who do not receive direct therapeutic benefit of the procedure themselves. In order to guarantee the donor's safety, it is important to optimise...

    journal_title:BMC surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2482-10-11

    authors: Dols LF,Kok NF,Terkivatan T,Tran TC,d'Ancona FC,Langenhuijsen JF,zur Borg IR,Alwayn IP,Hendriks MP,Dooper IM,Weimar W,Ijzermans JN

    更新日期:2010-03-25 00:00:00

  • An extremely rare case of lesser omental hernia in an elderly female patient following total colectomy.

    abstract:BACKGROUND:An intro-abdominal hernia through the lesser omentum is a rare but severe condition that can cause intestinal obstruction and other life-threating complications. Until now, only a handful of cases have been reported worldwide. The diagnosis of lesser omental hernia remains challenging for emergency surgeons ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-019-0665-7

    authors: Liu Z,He L,Jiao Y,Xu Z,Suo J

    更新日期:2020-01-16 00:00:00

  • Effects of parathyroidectomy on tumoral calcinosis in uremic patients with secondary hyperparathyroidism.

    abstract:BACKGROUND:Tumoral calcinosis (TC) is a rare disease derived from uremic secondary hyperparathyroidism (SHPT). However, parathyroidectomy (PTX) seems to be ineffective at relieving TC in some patients. In this study, we investigated the relationship between PTX and TC shrinkage. METHODS:We retrospectively followed up ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-019-0603-8

    authors: Wang J,Zeng M,Yang G,Huang Y,Wu B,Guo J,Wang N,Xing C

    更新日期:2019-09-11 00:00:00

  • Comparing laparoscopic cholecystectomy in patients with chronic obstructive pulmonary disease under spinal anesthesia and general anesthesia.

    abstract:BACKGROUND:Epidemiological data demonstrate that the worldwide prevalence of chronic obstructive pulmonary disease is increasing. These patients have an increased risk of mortality and morbidity and have constant limitations in airflow. Comparing laparoscopic cholecystectomy (LC) in patients with chronic obstructive pu...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-018-0396-1

    authors: Bayrak M,Altıntas Y

    更新日期:2018-08-20 00:00:00

  • Histological remodelling of demineralised bone matrix allograft in posterolateral fusion of the spine--an ex vivo study.

    abstract:BACKGROUND:Demineralised bone matrix (DBM) has shown to be effective in enhancing posterior fusion of the spine. Several animal studies and clinical investigations in humans showed its successful remodelling. The use of allogenic matrix may decrease the need of autologous bone graft and therefore helps prevent correspo...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-13-58

    authors: Bouaicha S,von Rechenberg B,Osterhoff G,Wanner GA,Simmen HP,Werner CM

    更新日期:2013-12-13 00:00:00

  • Comparison of sequential, delayed and simultaneous resection strategies for synchronous colorectal liver metastases.

    abstract:BACKGROUND:The present study aimed to compare the perioperative safety and long-term survival of patients with synchronous colorectal liver metastases undergoing sequential resection (SeR), delayed resection (DeR) and simultaneous resection (SiR). METHODS:From January 2007 to December 2016, data from patients undergoi...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-0681-7

    authors: Wang LJ,Wang HW,Jin KM,Li J,Xing BC

    更新日期:2020-01-17 00:00:00

  • Mid-term results of total hip arthroplasty with modified trochanteric osteotomy in Crowe type IV developmental dysplasia of the hip.

    abstract:BACKGROUND:This study aimed to explore mid-term clinical results of cementless total hip arthroplasty (THA) with modified trochanteric osteotomy in Crowe type IV developmental dysplasia of the hip (DDH). METHODS:Thirteen patients (13 hips) with Crowe type IV DDH who underwent THA with modified trochanteric osteotomy b...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/s12893-020-01002-4

    authors: Jin JY,Yoon TR,Park KS,Jin SY,Jung DM,Li QS

    更新日期:2021-01-06 00:00:00

  • Comparison of inpatient vs. outpatient anterior cervical discectomy and fusion: a retrospective case series.

    abstract:BACKGROUND:Spinal surgery is increasingly being done in the outpatient setting. We reviewed our experience with inpatient and outpatient single-level anterior cervical discectomy and fusion with plating (ACDF+P). METHODS:All patients undergoing single-level anterior cervical discectomy and fusion with plating between ...

    journal_title:BMC surgery

    pub_type: 杂志文章

    doi:10.1186/1471-2482-9-3

    authors: Liu JT,Briner RP,Friedman JA

    更新日期:2009-03-05 00:00:00