Abstract:
BACKGROUND:Transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Live donor nephrectomy is performed on healthy individuals who do not receive direct therapeutic benefit of the procedure themselves. In order to guarantee the donor's safety, it is important to optimise the surgical approach. Recently we demonstrated the benefit of laparoscopic nephrectomy experienced by the donor. However, this method is characterised by higher in hospital costs, longer operating times and it requires a well-trained surgeon. The hand-assisted retroperitoneoscopic technique may be an alternative to a complete laparoscopic, transperitoneal approach. The peritoneum remains intact and the risk of visceral injuries is reduced. Hand-assistance results in a faster procedure and a significantly reduced operating time. The feasibility of this method has been demonstrated recently, but as to date there are no data available advocating the use of one technique above the other. METHODS/DESIGN:The HARP-trial is a multi-centre randomised controlled, single-blind trial. The study compares the hand-assisted retroperitoneoscopic approach with standard laparoscopic donor nephrectomy. The objective is to determine the best approach for live donor nephrectomy to optimise donor's safety and comfort while reducing donation related costs. DISCUSSION:This study will contribute to the evidence on any benefits of hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy. TRIAL REGISTRATION:Dutch Trial Register NTR1433.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Dols LF,Kok NF,Terkivatan T,Tran TC,d'Ancona FC,Langenhuijsen JF,zur Borg IR,Alwayn IP,Hendriks MP,Dooper IM,Weimar W,Ijzermans JNdoi
10.1186/1471-2482-10-11subject
Has Abstractpub_date
2010-03-25 00:00:00pages
11issn
1471-2482pii
1471-2482-10-11journal_volume
10pub_type
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