Abstract:
BACKGROUND:Laparoscopic surgery has achieved significant results in elderly patients with colorectal cancer (CRC). In this study, we compared the short-term and long-term outcomes of open surgery and laparoscopic surgery in patients with CRC aged above 75 years at a single tertiary medical center. METHODS:We analyzed 967 patients who underwent curative resection for primary colorectal adenocarcinoma without distant metastasis between January 2009 and December 2015, in a single institution. Of the enrolled patients, 305 underwent laparoscopic surgery, and 662 received open laparotomy surgery. RESULTS:Compared to the patients who underwent open surgery, those who received laparoscopic surgery had significantly shorter postoperative stay (10.3 vs. 13.5 days p < 0.001) and similar postoperative morbidity (p = 0.354) and mortality (p = 0.082). In the laparoscopy cohort, six of 305 patients were converted to open surgery and one died. The long-term overall survival, cancer-specific survival, and recurrence rate were similar between both cohorts in each stage. CONCLUSIONS:Laparoscopic surgery is suitable for elderly patients owing to shorter postoperative stay, similar long-term outcomes with open surgery, and acceptable low conversion rates. For long-term overall and oncological outcomes, the results of laparoscopic surgery were similar to that of open surgery in each TNM stage.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Chern YJ,Hung HY,You JF,Hsu YJ,Chiang JM,Hsieh PS,Tsai WSdoi
10.1186/s12893-020-00967-6subject
Has Abstractpub_date
2020-11-23 00:00:00pages
294issue
1issn
1471-2482pii
10.1186/s12893-020-00967-6journal_volume
20pub_type
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