Randomised controlled trial of a Calcium Channel or Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Regime to Reduce Blood Pressure Variability following Ischaemic Stroke (CAARBS): a protocol for a feasibility study.

abstract：OBJECTIVES:To describe the role patient expectations play in general practitioners (GPs) antibiotic prescribing for upper respiratory tract infections (URTI). METHODS:Concurrent explanatory mixed methods approach using a cross-sectional survey and semistructured interviews. SETTINGS:Primary care GPs in Australia. PA...

journal_title：BMJ open

authors： Fletcher-Lartey S,Yee M,Gaarslev C,Khan R

更新日期：2016-10-24 00:00:00

abstract：INTRODUCTION:Physical activity (PA) has diverse benefits for physical and mental health and can reduce symptoms of mental illness. Adults with mental illness face practical, psychosocial and socioeconomic barriers to adopting and maintaining PA, and it is unclear how to effectively promote PA in this group. Supervised ...

journal_title：BMJ open

authors： Chapman JJ,Suetani S,Siskind D,Kisely S,Breakspear M,Byrne JH,Patterson S

更新日期：2018-09-08 00:00:00

abstract：OBJECTIVE:Previous clinical studies in adults from developed countries have implicated Helicobacter pylori infections in the development of thrombocytopenia. However, studies in children, particularly those from low-income countries, are unusually scarce. We examined the association between H. pylori infection and plat...

journal_title：BMJ open

authors： Baxendell K,Walelign S,Tesfaye M,Wordofa M,Abera D,Mesfin A,Wolde M,Desta K,Tsegaye A,Taye B

更新日期：2019-04-08 00:00:00

abstract：OBJECTIVES:This study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life. DESIGN:Prospective population-based cohort study. SETTING:British Regional Heart Study participants recruited ...

journal_title：BMJ open

authors： Aggio D,Papacosta O,Lennon L,Whincup P,Wannamethee G,Jefferis BJ

更新日期：2017-09-21 00:00:00

abstract：BACKGROUND:In recent years, there has been increased interest in the use of ultrasound technology in the evaluation of spinal and paraspinal regions. OBJECTIVE:This study aimed to investigate trends in spinal ultrasound research from 1994 to 2015 and compare the contributions of such research from different countries ...

journal_title：BMJ open

authors： Zhai X,Cui J,Shao J,Wang Q,Chen X,Wei X,Zhou X,Chen Z,Bai Y,Li M

更新日期：2017-10-22 00:00:00

abstract：INTRODUCTION:Fetal growth restriction (FGR) is a serious pregnancy complication, associated with increased rates of perinatal death and morbidity among survivors. Most commonly FGR results from placental insufficiency, where the placenta fails to deliver the oxygen and nutrients required for normal fetal growth. This l...

journal_title：BMJ open

authors： Palmer KR,Mockler JC,Davies-Tuck ML,Miller SL,Goergen SK,Fahey MC,Anderson PJ,Groom KM,Wallace EM

更新日期：2019-06-22 00:00:00

abstract：INTRODUCTION:Low-cost interventions providing self-management support are needed for people with coronary artery disease (CAD) and diabetes. Mobile phone text messaging provides a potential vehicle for this. The SupportMe Trial aims to assess the feasibility of embedding a text messaging programme into routine clinical...

journal_title：BMJ open

authors： Cheung NW,Redfern J,Thiagalingam A,Hng TM,Islam SMS,Haider R,Faruquie S,Chow C,SupportMe investigators.

更新日期：2019-06-19 00:00:00

abstract：OBJECTIVE:To examine the impact of caesarean section on breastfeeding indicators-early initiation of breastfeeding, exclusive breastfeeding under 6 months and children ever breastfed (at least once)-in sub-Saharan Africa. DESIGN:Secondary analysis of Demographic and Health Surveys (DHS). SETTING:Thirty-three low-inco...

journal_title：BMJ open

authors： Yisma E,Mol BW,Lynch JW,Smithers LG

更新日期：2019-09-04 00:00:00

abstract：OBJECTIVE:To determine whether occupational exposure to silica dust causes an increased risk of developing Crohn's disease (CD) and ulcerative colitis (UC). DESIGN:Case-control study of CD (K50) and UC (K51) from 2007 through 2016. Controls were matched to cases (2:1) based on age, sex and county at the time of diagno...

journal_title：BMJ open

authors： Wallden A,Graff P,Bryngelsson IL,Fornander L,Wiebert P,Vihlborg P

更新日期：2020-02-16 00:00:00

abstract：OBJECTIVES:To explore whether knowledge about the harms of ultraviolet radiation (UVR) influences UK university students' sun-related behaviours and examine in depth their attitudes towards: sun protection, natural and artificial tanning behaviours. DESIGN:Qualitative methodology with 15 semistructured, individual int...

journal_title：BMJ open

authors： Kirk L,Greenfield S

更新日期：2017-03-13 00:00:00

abstract：INTRODUCTION:Insomnia is a highly prevalent, often debilitating and economically burdensome sleep disorder with limited effective therapies. Few data are available to understand which of the therapeutic alternatives is the most effective for patients with insomnia, especially for Traditional Chinese Medicine (TCM). Chi...

journal_title：BMJ open

authors： Liu QQ,Zhang J,Guo RJ,Xie YZ,Fu QN,He T,Zhu XQ,Du J,Yang J,Wang JL,Wei MM,Li QQ,Shi GX,Liu CZ

更新日期：2016-02-02 00:00:00

abstract：INTRODUCTION:The importance of health-related quality of life (HRQoL) is increasing and many healthcare authorities recommend the use of measures that account for both mortality and morbidity. This study will determine, for the first time in Romania, value sets for EuroQoL-five-dimensions-3-level (EQ-5D-3L) and EQ-5D-5...

journal_title：BMJ open

authors： Olariu E,Paveliu MS,Baican E,Oluboyede Y,Vale L,Niculescu-Aron IG

更新日期：2019-08-18 00:00:00

abstract：BACKGROUND:Health risk behaviours are prominent in late adolescence and young adulthood, yet UK population-level research examining the relationship between drug or alcohol use and sexual health and behaviour among young people is scarce, despite public health calls for an integrated approach to health improvement. Our...

journal_title：BMJ open

authors： Khadr SN,Jones KG,Mann S,Hale DR,Johnson AM,Viner RM,Mercer CH,Wellings K

更新日期：2016-06-30 00:00:00

abstract：INTRODUCTION:Reducing length of hospital stay for stroke survivors often creates a shift in the responsibility of care towards informal carers. Adjustment to the caregiving process is experienced by many carers as overwhelming, complex and demanding and can have a detrimental impact on mental and physical health and we...

journal_title：BMJ open

authors： Walker MF,Thomas SA,Whitehead PJ,Condon L,Fisher RJ,Kontou E,Benford P,Cobley C

更新日期：2017-10-22 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the effects of long-term offshore work on cerebral oxygenation oscillations in sailors based on the wavelet phase coherence (WPCO) of near-infrared spectroscopy (NIRS) signals. METHODS:The fatigue severity scale (FSS) was first applied to assess the fatigue level of ...

journal_title：BMJ open

authors： Bu L,Li J,Li F,Liu H,Li Z

更新日期：2016-11-03 00:00:00

abstract：OBJECTIVES:To determine differences in alarm pressure between two otherwise comparable neonatal intensive care units (NICUs) differing in architectural layout-one of a single-family room (SFR) design and the other of an open bay area (OBA) design. DESIGN:Retrospective audit of more than 2000 patient days from each NIC...

journal_title：BMJ open

authors： Joshi R,Straaten HV,Mortel HV,Long X,Andriessen P,Pul CV

更新日期：2018-06-30 00:00:00

abstract：INTRODUCTION:Delirium is frequently observed in the intensive care unit (ICU) population, in particular. Until today, there is no evidence for any reliable pharmacological intervention to treat delirium. The Basel BOMP-AID (Better Outcome with Melatonin compared to Placebo Administered to normalize sleep-wake cycle and...

journal_title：BMJ open

authors： Hollinger A,von Felten S,Sutter R,Huber J,Tran F,Reinhold S,Abdelhamid S,Todorov A,Gebhard CE,Cajochen C,Steiner LA,Siegemund M

更新日期：2020-04-30 00:00:00

abstract：OBJECTIVE:To investigate the effects of vitreomacular adhesion (VMA), vitreomacular separation (VMS) and absence of vitreous gel due to vitrectomy on macular thickness measured in the spectral domain optical coherence tomographic (SD-OCT) images. DESIGN:A longitudinal, retrospective, observational study. SETTING:Seco...

journal_title：BMJ open

authors： Kumagai K,Hangai M,Furukawa M,Suetsugu T,Ogino N

更新日期：2016-09-30 00:00:00

abstract：BACKGROUND:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a condition characterised by severe and persistent fatigue, neurological disturbances, autonomic and endocrine dysfunctions and sleep difficulties that have a pronounced and significant impact on individuals' lives. Current National Institute for...

journal_title：BMJ open

authors： Arroll MA,Howard A

更新日期：2012-11-19 00:00:00

abstract：INTRODUCTION:Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving or preserving motor function. Current research on CP care does not always take into account indi...

journal_title：BMJ open

authors： Almoajil H,Dawes H,Hopewell S,Toye F,Jenkinson C,Theologis T

更新日期：2020-03-04 00:00:00

abstract：OBJECTIVE:This research aims to determine the long-term impact of the Bloor Street Viaduct suicide barrier on rates of suicide in Toronto and whether media reporting had any impact on suicide rates. DESIGN:Natural experiment. SETTING:City of Toronto, Canada; records at the chief coroner's office of Ontario 1993-2003 ...

journal_title：BMJ open

authors： Sinyor M,Schaffer A,Redelmeier DA,Kiss A,Nishikawa Y,Cheung AH,Levitt AJ,Pirkis J

更新日期：2017-06-19 00:00:00

abstract：OBJECTIVE:To clarify the pathophysiological basis of persistent geotropic positional nystagmus (PGN) in patients with the horizontal canal type of benign paroxysmal positional vertigo (H-BPPV), the time constant (TC) of nystagmus and the relationship between its slow phase eye velocity (SPV) and the angle of head rotat...

journal_title：BMJ open

authors： Imai T,Matsuda K,Takeda N,Uno A,Kitahara T,Horii A,Nishiike S,Inohara H

更新日期：2015-01-13 00:00:00

abstract：OBJECTIVE:To assess the 24-month cost-effectiveness of total knee replacement (TKR) plus non-surgical treatment compared with non-surgical treatment with the option of later TKR if needed. METHODS:100 adults with moderate-to-severe knee osteoarthritis found eligible for TKR by an orthopaedic surgeon in secondary care ...

journal_title：BMJ open

authors： Skou ST,Roos E,Laursen M,Arendt-Nielsen L,Rasmussen S,Simonsen O,Ibsen R,Larsen AT,Kjellberg J

更新日期：2020-01-15 00:00:00

abstract：OBJECTIVES:To describe low-density lipoprotein (LDL) cholesterol management and lipid-lowering treatment patterns in patients with a cardiovascular (CV) event. DESIGN:Retrospective cohort study using Clinical Practice Research Datalink records linked with Hospital Episode Statistics data. SETTING:Routine clinical pra...

journal_title：BMJ open

authors： Danese MD,Gleeson M,Kutikova L,Griffiths RI,Khunti K,Seshasai SRK,Ray KK

更新日期：2017-05-10 00:00:00

abstract：BACKGROUND:Osteoporosis is an age-related disease with progressive loss of bone, leading to fragile bone. It is one of the major health issues in older adults and causes medical, social and economic impacts globally. Patients with osteoporosis have high risk of osteoporotic fractures. Low-magnitude high-frequency vibra...

journal_title：BMJ open

authors： Chow SKH,Ho CY,Wong HW,Chim YN,Wong RWM,Cheung WH

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVE:To pilot and feasibility-test supervised final year undergraduate pharmacy student-led medication reviews for patients with diabetes to enable definitive trial design. METHOD:Third year pharmacy students were recruited from one UK School of Pharmacy and trained to review patient's medical records and provide...

journal_title：BMJ open

authors： Adams RP,Barton G,Bhattacharya D,Grassby PF,Holland R,Howe A,Norris N,Shepstone L,Wright DJ

更新日期：2015-11-04 00:00:00

abstract：OBJECTIVES:To determine the prevalence of intimate partner violence (IPV) in pregnancy and to understand associations and determinants. DESIGN:Cross-sectional survey. SETTING:Two rural health clinics in post-conflict northern Uganda. PARTICIPANTS:Women attending two rural health clinics for a new service providing c...

journal_title：BMJ open

authors： Clarke S,Richmond R,Black E,Fry H,Obol JH,Worth H

更新日期：2019-11-26 00:00:00

abstract：BACKGROUND:Achilles tendon injuries give rise to substantial long-lasting morbidity and pose considerable challenges for clinicians and patients during the lengthy healing period. Current treatment strategies struggle to curb the burden of this injury on health systems and society due to lengthy rehabilitation, work ab...

journal_title：BMJ open

authors： Alsousou J,Keene DJ,Hulley PA,Harrison P,Wagland S,Byrne C,Schlüssel MM,Dutton SJ,Lamb SE,Willett K

更新日期：2017-11-16 00:00:00

abstract：OBJECTIVES:Taxing sugar-sweetened beverages (SSBs) is now advocated, and implemented, in many countries as a measure to reduce the purchase and consumption of sugar to tackle obesity. To date, there has been little consideration of the potential impact that such a measure could have if extended to other sweet foods, su...

journal_title：BMJ open

authors： Smith RD,Cornelsen L,Quirmbach D,Jebb SA,Marteau TM

更新日期：2018-04-26 00:00:00

abstract：INTRODUCTION:This article describes two randomised controlled trials that will evaluate the effectiveness and cost-effectiveness of Self-Help Plus (SH+), a group self-help intervention developed by the WHO to reduce distress. In these trials SH+ is being tested as a preventative intervention to lower the incidence of m...

journal_title：BMJ open

authors： Purgato M,Carswell K,Acarturk C,Au T,Akbai S,Anttila M,Baumgartner J,Bailey D,Biondi M,Bird M,Churchill R,Eskici S,Hansen LJ,Heron P,Ilkkursun Z,Kilian R,Koesters M,Lantta T,Nosè M,Ostuzzi G,Papola D,Popa M,Si

更新日期：2019-05-14 00:00:00