Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials.

abstract：OBJECTIVES:To systematically analyse the effect of pharmacological treatment of hypertension (HTN) on cognitive decline in older adults. METHODS:Randomised, placebo-controlled trials with a prespecified quantitative outcome of cognition and a pharmacological intervention for at least 12 months to treat HTN in older ad...

journal_title：BMJ open

authors： Gupta A,Perdomo S,Billinger S,Beddhu S,Burns J,Gronseth G

更新日期：2020-11-17 00:00:00

abstract：OBJECTIVES:The establishment of the Family Physician (FP) programme in the rural areas of Iran in 2005 has made health services accessible and affordable. This paper aims to assess the overall trends of maternal and child health (MCH) indicators in a 20-year period and possible effects of the FP programme (intervention...

journal_title：BMJ open

authors： Jabbari Beyrami H,Doshmangir L,Ahmadi A,Asghari Jafarabadi M,Khedmati Morasae E,Gordeev VS

更新日期：2019-01-15 00:00:00

abstract：INTRODUCTION:Hospitals are complex systems and optimising their function is critical to the provision of high quality, cost effective healthcare. Metrics of performance have to date focused on the performance of individual elements rather than the whole system. Manipulation of individual elements of a complex system wi...

journal_title：BMJ open

authors： Kohler K,Ercole A

更新日期：2020-02-09 00:00:00

abstract：OBJECTIVE:This study aims to assess the needs of people with disabilities and their level of inclusion in social protection programmes. DESIGN:Population based-survey with a nested case-control study. SETTING:Morropon, a semiurban district located in Piura, northern Peru. PARTICIPANTS:For the population survey, a tw...

journal_title：BMJ open

authors： Bernabe-Ortiz A,Diez-Canseco F,Vasquez A,Kuper H,Walsham M,Blanchet K

更新日期：2016-08-26 00:00:00

abstract：OBJECTIVES:Mortality has declined in people with HIV infection, subsequent to the improved access to antiretroviral therapy (ART). We assessed the incidence and determinants of mortality among patients with HIV-1 infection who were started on ART in a referral treatment centre for HIV infection in Yaounde, Cameroon. D...

journal_title：BMJ open

authors： Poka-Mayap V,Pefura-Yone EW,Kengne AP,Kuaban C

更新日期：2013-07-13 00:00:00

abstract：OBJECTIVES:To investigate the role of socioeconomic status and psychological stress to potential associations between confidence in the future and a wide range of health-related behaviours. DESIGN:Web-based cross-sectional study including an 'Electronic Health Check' at the Finnish Happiness-Flourishing Study website ...

journal_title：BMJ open

authors： Joutsenniemi K,Härkänen T,Pankakoski M,Langinvainio H,Mattila AS,Saarelma O,Lönnqvist J,Mustonen P

更新日期：2013-06-20 00:00:00

abstract：OBJECTIVE:This study examines the association between profession-specific work environments and the 7-day mortality of patients admitted to these units with acute myocardial infarction (AMI), stroke and hip fracture. DESIGN:A cross-sectional study combining patient mortality data extracted from the South-Eastern Norwa...

journal_title：BMJ open

authors： Brubakk K,Svendsen MV,Hofoss D,Hansen TM,Barach P,Tjomsland O

更新日期：2019-12-15 00:00:00

abstract：OBJECTIVES:Scientific literacy is assumed necessary for appraising the reliability of health claims. Using a national science achievement test, we explored whether students located at the lower quartile on the latent trait (scientific literacy) scale were likely to identify a health claim in a fictitious brief news rep...

journal_title：BMJ open

authors： Nordheim LV,Pettersen KS,Espehaug B,Flottorp SA,Guttersrud Ø

更新日期：2019-10-18 00:00:00

abstract：INTRODUCTION:Mobility limitation is common and often results from neurological and musculoskeletal health conditions, ageing and/or physical inactivity. In consultation with consumers, clinicians and policymakers, we have developed two affordable and scalable intervention packages designed to enhance physical activity ...

journal_title：BMJ open

authors： Hassett L,Tiedemann A,Hinman RS,Crotty M,Hoffmann T,Harvey L,Taylor NF,Greaves C,Treacy D,Jennings M,Milat A,Bennell KL,Howard K,van den Berg M,Pinheiro M,Wong S,Kirkham C,Ramsay E,O'Rourke S,Sherrington C

更新日期：2020-11-03 00:00:00

abstract：INTRODUCTION:Preterm babies are among the highest users of parenteral nutrition (PN) of any patient group, but there is wide variation in commencement, duration, and composition of PN and uncertainty around which groups will benefit from early introduction. Recent studies in critically unwell adults and children sugges...

journal_title：BMJ open

authors： Webbe J,Longford N,Uthaya S,Modi N,Gale C

更新日期：2019-07-09 00:00:00

abstract：OBJECTIVE:There have been calls to remove 'carcinoma' from terminology for in situ cancers such as ductal carcinoma in situ (DCIS), to reduce overdiagnosis and overtreatment. We investigated the effect of describing DCIS as 'abnormal cells' versus 'pre-invasive breast cancer cells' on women's concern and treatment pref...

journal_title：BMJ open

authors： McCaffery K,Nickel B,Moynihan R,Hersch J,Teixeira-Pinto A,Irwig L,Barratt A

更新日期：2015-11-02 00:00:00

abstract：INTRODUCTION:Discharge documents are important for transferring information from hospitals to the referring clinician; in the UK and many countries, this is often the patient's general practitioner or family physician. However, patients may or may not receive their discharge letters, and whether patients should routine...

journal_title：BMJ open

authors： Weetman K,Wong G,Scott E,Schnurr S,Dale J

更新日期：2017-11-12 00:00:00

abstract：INTRODUCTION:A significant proportion of the global burden of disease has been attributed to mental and behavioural disorders. People with mental disorders (MDs) have lower levels of health-related quality of life than those without MDs. Several studies have shown that in low-resource countries, a range of social deter...

journal_title：BMJ open

authors： Uddin MN,Bhar S,Al Mahmud A,Islam FMA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To determine research priorities for the management of broken bones of the upper limb in people over 50, which represent the shared priorities of patients, their families, carers and healthcare professionals. DESIGN/SETTING:A national (UK) research priority setting partnership. PARTICIPANTS:People aged 50 a...

journal_title：BMJ open

authors： Sheehan WJ,Williams MA,Paskins Z,Costa ML,Fernandez MA,Gould J,Bell P,Baird L,Grant R,Ellis P,White C,Arnel L,Exell L,Gwilym S

更新日期：2019-12-15 00:00:00

abstract：OBJECTIVES:Improving the quality of primary care is an important strategy to improve health outcomes. However, responses to continuous quality improvement (CQI) initiatives are variable, likely due in part to a mismatch between interventions and context. This project aimed to understand the successful implementation of...

journal_title：BMJ open

authors： Larkins S,Carlisle K,Turner N,Taylor J,Copley K,Cooney S,Wright R,Matthews V,Thompson S,Bailie R

更新日期：2019-05-24 00:00:00

abstract：OBJECTIVE:To identify factors influencing cardiologists' and hospitalists' decisions regarding palliative care referral among hospitalised patients with advanced heart failure. DESIGN:An exploratory, randomised vignette-based survey. SETTING:Cardiology and hospitalist divisions at three Michigan State institutions an...

journal_title：BMJ open

authors： Abedini NC,Guo G,Hummel SL,Bozaan D,Beasley M,Cowger J,Chopra V

更新日期：2020-12-15 00:00:00

abstract：:Aims To study long-term sick-listed patients' self-estimated ability to return to work after experiences of healthcare encounters that made them feel either respected or wronged. Methods A cross-sectional and questionnaire-based survey was used to study a sample of long-term sick-listed patients (n=5802 respondents)....

journal_title：BMJ open

authors： Lynöe N,Wessel M,Olsson D,Alexanderson K,Helgesson G

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:The aim of the present study is to investigate the effectiveness of pulsed low-frequency magnetic field (PLFMF) on the management of chronic low back pain (CLBP). METHODS AND ANALYSIS:A randomised double-blinded controlled clinical trial will be conducted, involving 200 patients with CLBP. Participants wi...

journal_title：BMJ open

authors： Abdulla FA,Alsaadi S,Sadat-Ali M,Alkhamis F,Alkawaja H,Lo S

更新日期：2019-06-09 00:00:00

abstract：INTRODUCTION:The recent introduction of incision-less lesional neurosurgery using Gamma Knife and MRI-guided focused ultrasound has revived interest in lesional treatment options for tremor disorders. Preliminary literature researches reveal that the consistency of treatment effects after lesional neurosurgery for trem...

journal_title：BMJ open

authors： Schreglmann SR,Krauss JK,Chang JW,Bhatia KP,Kägi G

更新日期：2017-05-09 00:00:00

abstract：INTRODUCTION:Idiopathic Parkinson's disease (PD) is a progressive neurodegenerative disorder related to α-synuclein misfolding and aggregation. For this reason, it belongs to the family of 'synucleinopathies', which also includes some other neurological diseases. Although imaging and ancillary investigations may be hel...

journal_title：BMJ open

authors： Eusebi P,Hansson O,Paciotti S,Orso M,Chiasserini D,Calabresi P,Blennow K,Parnetti L

更新日期：2017-11-22 00:00:00

abstract：OBJECTIVE/DESIGN:It remains unclear as to the efficacy of readiness for change measurements in child and adolescent obesity intervention programmes. This observational study aimed to determine whether the caregiver's stage of change could predict outcome and adherence to treatment in an intensive intervention programme...

journal_title：BMJ open

authors： Anderson YC,Dolan GMS,Wynter LE,Treves KF,Wouldes TA,Grant CC,Cave TL,Smiley AJ,Derraik JGB,Cutfield WS,Hofman PL

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVE:To assess the prevalence of cerebral stroke in the general population of Beijing and its association with systemic risk factors and ocular diseases. SETTING:The population-based Beijing Eye Study was conducted in a rural and urban region of Beijing. PARTICIPANTS:With eligibility criteria of age 50+ years an...

journal_title：BMJ open

authors： Wang YX,Wei WB,Xu L,Jonas JB

更新日期：2020-09-10 00:00:00

abstract：INTRODUCTION:Chronic Obstructive Pulmonary Disease (COPD)and asthma affect more than 10% of the population. Most patients use their inhaler incorrectly, mainly the elderly, thereby becoming more susceptible to poor clinical control and exacerbations. Placebo device training is regarded as one of the best teaching metho...

journal_title：BMJ open

authors： Maricoto T,Correia-de-Sousa J,Taborda-Barata L

更新日期：2019-01-28 00:00:00

abstract：INTRODUCTION:Cigarette smoking is one of the leading causes of early death in the UK and worldwide. Public health guidance recommends the use of varenicline, bupropion and nicotine replacement therapy (NRT) as smoking cessation aids in the UK. Additionally, the first electronic cigarette has been licensed for use as a ...

journal_title：BMJ open

authors： Thomas KH,Caldwell D,Dalili MN,Gunnell D,Munafò MR,Stevenson M,Welton NJ

更新日期：2017-06-17 00:00:00

abstract：OBJECTIVES:The objectives of this study were to describe the methods used to assess the quality of linkage between records of babies' birth registration and hospital birth records, and to evaluate the potential bias that may be introduced because of these methods. DESIGN/SETTING:Data from the civil registration and th...

journal_title：BMJ open

authors： Coathup V,Macfarlane A,Quigley M

更新日期：2020-10-26 00:00:00

abstract：OBJECTIVE:Illness perception has been shown to have significant influence on the well-being and coping strategies of persons living with chronic medical conditions. Understanding of how women living with breast cancer cognitively and emotionally represent their illness and coping strategies used is likely to help in de...

journal_title：BMJ open

authors： Kugbey N,Oppong Asante K,Meyer-Weitz A

更新日期：2020-07-14 00:00:00

abstract：INTRODUCTION:Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits fibrinolysis by blocking lysine-binding sites on plasminogen, which contribute to reduced bleeding, the need for transfusion and mortality. Although there is reliable evidence of the efficacy of TXA, its effects on other...

journal_title：BMJ open

authors： Murao S,Nakata H,Yamakawa K

更新日期：2020-06-22 00:00:00

abstract：INTRODUCTION:Despite advances in infection prevention and control, catheter-associated urinary tract infections (CAUTIs) are common and remain problematic. A number of measures can be taken to reduce the risk of CAUTI in hospitals. Appropriate urinary catheter insertion procedures are one such method. Reducing bacteria...

journal_title：BMJ open

authors： Mitchell BG,Fasugba O,Gardner A,Koerner J,Collignon P,Cheng AC,Graves N,Morey P,Gregory V

更新日期：2017-11-28 00:00:00

abstract：OBJECTIVE:Limited research has assessed the association between patterns of body mass index (BMI) change across adulthood and mortality. We aimed to identify groups of individuals who followed specific group-based BMI trajectories across adulthood, using weight collected on three occasions and recalled data from early ...

journal_title：BMJ open

authors： Yang Y,Dugué PA,Lynch BM,Hodge AM,Karahalios A,MacInnis RJ,Milne RL,Giles GG,English DR

更新日期：2019-08-10 00:00:00

abstract：INTRODUCTION:Multifarious chronic obstructive pulmonary disease (COPD) guidelines have been published by local, national and global respiratory societies. These guidelines subsume holistic evidence based on recommendations to diagnose, treat, prevent and manage acute exacerbation with COPD. Despite the existing compreh...

journal_title：BMJ open

authors： Issac H,Moloney C,Taylor M,Lea J

更新日期：2020-07-20 00:00:00