Cerebrospinal fluid biomarkers for the diagnosis and prognosis of Parkinson's disease: protocol for a systematic review and individual participant data meta-analysis.

abstract：OBJECTIVES:Use of the term 'patient' has been recently debated, compared with alternatives including 'consumer' and 'client'. This scoping study aimed to provide an integrated view of preferred labels across healthcare contexts and countries to clarify labelling preferences of individuals accessing healthcare. DESIGN:...

journal_title：BMJ open

authors： Costa DSJ,Mercieca-Bebber R,Tesson S,Seidler Z,Lopez AL

更新日期：2019-03-07 00:00:00

abstract：OBJECTIVES:To investigate the association between area deprivation at municipality level with low perceived social support, independent of individual socioeconomic position and demographic characteristics. To assess whether there are gender inequalities in this association. DESIGN:Cross-sectional multilevel analysis o...

journal_title：BMJ open

authors： Mena E,Kroll LE,Maier W,Bolte G

更新日期：2018-04-12 00:00:00

abstract：INTRODUCTION:In acute pulmonary embolism (PE), poor outcome is usually related to right ventricular (RV) failure due to the increase in RV afterload. Treatment of PE with RV failure without shock is controversial and usually relies on fluid expansion to increase RV preload. However, several studies suggest that fluid e...

journal_title：BMJ open

authors： Gallet R,Meyer G,Ternacle J,Biendel C,Brunet A,Meneveau N,Rosario R,Couturaud F,Sebbane M,Lamblin N,Bouvaist H,Coste P,Maitre B,Bastuji-Garin S,Dubois-Rande JL,Lim P

更新日期：2015-05-22 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of mild cognitive impairment and the relationship with plasma aluminium among aluminium workers. DESIGN:This was a cross-sectional case-control study in the SH Aluminium Factory, China. SETTING:The university and affiliated hospital cooperated in the study. PARTICIPANTS:There...

journal_title：BMJ open

authors： Meng H,Wang S,Guo J,Zhao Y,Zhang S,Zhao Y,Niu Q

更新日期：2019-06-16 00:00:00

abstract：PURPOSE:We have established a prospective cohort of 1959 patients with chronic Chagas cardiomyopathy to evaluate if a clinical prediction rule based on ECG, brain natriuretic peptide (BNP) levels, and other biomarkers can be useful in clinical practice. This paper outlines the study and baseline characteristics of the ...

journal_title：BMJ open

authors： Cardoso CS,Sabino EC,Oliveira CD,de Oliveira LC,Ferreira AM,Cunha-Neto E,Bierrenbach AL,Ferreira JE,Haikal DS,Reingold AL,Ribeiro AL

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVE:High-performance marine craft personnel (HPMCP) are regularly exposed to vibration and repeated shock (VRS) levels exceeding maximum limitations stated by international legislation. Whereas such exposure reportedly is detrimental to health and performance, the epidemiological data necessary to link these adve...

journal_title：BMJ open

authors： Lo Martire R,de Alwis MP,Äng BO,Garme K

更新日期：2017-07-20 00:00:00

abstract：INTRODUCTION:Minority populations in the USA are disproportionately affected by cardiovascular conditions. Reduced responsiveness to clopidogrel among carriers of CYP2C19 variants has been reported in patients with either coronary artery disease (CAD) or acute coronary syndrome (ACS) after the percutaneous coronary int...

journal_title：BMJ open

authors： Hernandez-Suarez DF,Melin K,Marin-Maldonado F,Nunez HJ,Gonzalez AF,Gonzalez-Sepulveda L,Rivas-Tumanyan S,Naik H,Ruaño G,Scott SA,Duconge J

更新日期：2020-08-06 00:00:00

abstract：OBJECTIVE:In the field of palliative care (PC) as it is integrated into heart failure (HF) treatment, it is essential to explore the patient experience and build on this knowledge for the further development of PC practice and policy. Based on an intervention study, this paper explores what patients with HF find signif...

journal_title：BMJ open

authors： Roikjær SG,Simonÿ CP,Timm HU

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVE:To determine if low-dose weekly chloroquine (CQ) therapy improves recovery from malaria-associated anaemia. DESIGN:Proof of concept randomised clinical trial. SETTING:West Kiang District, Lower River Region, The Gambia. PARTICIPANTS:Children resident in participating communities, aged 12-72 months, with un...

journal_title：BMJ open

authors： Cox SE,Nweneka CV,Doherty CP,Fulford AJ,Moore SE,Prentice AM

更新日期：2013-07-04 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a model of rural community health service (CHS) on the use and acceptability of primary healthcare services. DESIGN:Quasi-experimental. SETTING:Two adjacent rural counties in China. PARTICIPANTS:5842 residents in 2009 and 3807 in 2010 from 980 households in 7 intervention township...

journal_title：BMJ open

authors： Liu Y,Yuan Z,Liu Y,Jayasinghe UW,Harris MF

更新日期：2014-02-28 00:00:00

abstract：OBJECTIVES:Sickness absence (SA) is a widely studied integrated measure of health status. To better understand how SA behaves over time (SA trajectory) a longitudinal and individual-centred approach will allow identifying groups of individuals who share common characteristics. The aim of this study was to identify and ...

journal_title：BMJ open

authors： Ubalde-Lopez M,Hernando-Rodriguez JC,Benavides FG,Serra L

更新日期：2019-07-03 00:00:00

abstract：OBJECTIVES:While bidirectional relationships exist between body weight and physical activity, direction of causality remains uncertain and previous studies have been limited by self-reported activity or weight and small sample size. We investigated the prospective relationships between weight and physical activity. DE...

journal_title：BMJ open

authors： Preiss D,Thomas LE,Wojdyla DM,Haffner SM,Gill JM,Yates T,Davies MJ,Holman RR,McMurray JJ,Califf RM,Kraus WE,NAVIGATOR Investigators.

更新日期：2015-08-14 00:00:00

abstract：INTRODUCTION:Chronic inguinal pain is a frequently occurring problem in athletes. A diagnosis of inguinal disruption is performed by exclusion of other conditions causing groin pain. Up to now, conservative medical management is considered to be the primary treatment for this condition. Relevant large and prospective c...

journal_title：BMJ open

authors： Voorbrood CE,Goedhart E,Verleisdonk EJ,Sanders F,Naafs D,Burgmans JP

更新日期：2016-01-06 00:00:00

abstract：INTRODUCTION:Diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) are the major causes of sight loss in people with diabetes. Due to the increased prevalence of diabetes, the workload related to these complications is increasing making it difficult for Hospital Eye Services (HSE) to meet demands. ...

journal_title：BMJ open

authors： Lois N,Cook J,Aldington S,Waugh N,Mistry H,Sones W,McAuley D,Aslam T,Bailey C,Chong V,Ghanchi F,Scanlon P,Sivaprasad S,Steel D,Styles C,McNally C,Rice R,Prior L,Azuara-Blanco A,EMERALD Study Group.

更新日期：2019-06-28 00:00:00

abstract：OBJECTIVES:To compare cardiovascular risk factors as well as rates of cardiovascular diseases in middle-aged women from urban areas in Scotland and Sweden. DESIGN:Comparative cross-sectional study. SETTING:Data from the general population in urban areas of Scotland and the general population in two major Swedish citi...

journal_title：BMJ open

authors： Wennerholm C,Bromley C,Johansson A,Nilsson S,Frank J,Faresjö T

更新日期：2017-08-07 00:00:00

abstract：OBJECTIVES:This study examined patient adherence and persistence to oral bisphosphonates for the treatment of osteoporosis in real-world settings. METHODS:A systematic review was completed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Medical Literature Analysis and Retrieval Sys...

journal_title：BMJ open

authors： Fatoye F,Smith P,Gebrye T,Yeowell G

更新日期：2019-04-14 00:00:00

abstract：OBJECTIVE:To identify components of a proposed blood-borne virus (BBV) population screening programme and its associated consent procedure that both the public and health practitioners (HPs) would find acceptable. The proposed BBV screening system would aim to reduce late diagnosis of BBVs and be used in patients under...

journal_title：BMJ open

authors： Crane D,Henderson EJ,Chadwick DR

更新日期：2017-05-29 00:00:00

abstract：OBJECTIVES:Medical image analysis practices face challenges that can potentially be addressed with algorithm-based segmentation tools. In this study, we map the field of automatic MR brain lesion segmentation to understand the clinical applicability of prevalent methods and study designs, as well as challenges and limi...

journal_title：BMJ open

authors： Gryska E,Schneiderman J,Björkman-Burtscher I,Heckemann RA

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:We assessed the impact of political conflict (Boko Haram) on tuberculosis (TB) case notifications in Adamawa State in North-east Nigeria. DESIGN:A retrospective analysis of TB case notifications from TB registers (2010-2016) to describe changes in TB notification, sex and age ratios by the degree of conflict ...

journal_title：BMJ open

authors： Pembi E,John S,Dumre SP,Ahmadu BU,Vuong NL,Ebied A,Mizukami S,Huy NT,Cuevas LE,Hirayama K

更新日期：2020-09-16 00:00:00

abstract：OBJECTIVES:To derive a tool to determine Urgent Care Center (UCC) crowding and investigate the association between different levels of UCC overcrowding and negative patient care outcomes. DESIGN:Prospective pilot study. SETTING:Single centre study in the USA. PARTICIPANTS:3565 patients who registered at UCC during t...

journal_title：BMJ open

authors： Wang H,Robinson RD,Cowden CD,Gorman VA,Cook CD,Gicheru EK,Schrader CD,Jayswal RD,Zenarosa NR

更新日期：2015-04-14 00:00:00

abstract：OBJECTIVE:Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). When approved by the Food and Drug Administration (FDA) in 1988, a maximum daily dosage limit of 800 mg (eight tablets) of the 25/100 carbidopa/levodopa formulat...

journal_title：BMJ open

authors： Brodell DW,Stanford NT,Jacobson CE,Schmidt P,Okun MS

更新日期：2012-12-11 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the current work distribution of health professionals from a public Ugandan medical school in a period of major donor funding for HIV programmes. We explore the hypothesis that programmes initiated under unprecedented health investments from the US President's Emerge...

journal_title：BMJ open

authors： Bajunirwe F,Twesigye L,Zhang M,Kerry VB,Bangsberg DR

更新日期：2013-05-31 00:00:00

abstract：OBJECTIVES:Mental health problems and hazardous alcohol consumption often co-exist. Hazardous drinking could have a negative impact on different aspects of health and also negatively influence the effect of mental health treatment. The aims of this study were to examine if alcohol consumption patterns changed after tre...

journal_title：BMJ open

authors： Strid C,Hallgren M,Forsell Y,Kraepelien M,Öjehagen A

更新日期：2019-11-10 00:00:00

abstract：INTRODUCTION:This study aims to explore the prospective association between the dietary quality (DQ) of preschoolers and their health status in Hong Kong, with the body mass index as the main outcome variable. METHODS AND ANALYSIS:This prospective cohort study has recruited 3539 children aged between 2 and 4 years old...

journal_title：BMJ open

authors： Lee A,Cheung CK,Lo K,Keung VM,Mui LW,Tam WWS

更新日期：2017-11-08 00:00:00

abstract：OBJECTIVES:The present study aimed to assess the level of knowledge on peripherally inserted central catheter (PICC) maintenance among nurses in China and to analyse the related factors influencing this variable. DESIGN:A cross-sectional survey. SETTING:Ninety-one hospitals at three different levels in Hunan Province...

journal_title：BMJ open

authors： Xu B,Zhang J,Hou J,Ma M,Gong Z,Tang S

更新日期：2020-05-21 00:00:00

abstract：INTRODUCTION:Cardiovascular disease (CVD) remains a major cause of morbidity and premature mortality globally. Despite the availability of low-cost evidence based medicines, there is a significant treatment gap in those with established or at high risk of CVD in the primary care setting. Pharmacist-based interventions ...

journal_title：BMJ open

authors： Chaudhri K,Hayek A,Liu H,Joshi R

更新日期：2019-08-05 00:00:00

abstract：PURPOSE:Depression is the most common psychiatric disorder and the largest contributor to global disability. The Australian Genetics of Depression study was established to recruit a large cohort of individuals who have been diagnosed with depression at some point in their lifetime. The purpose of establishing this coho...

journal_title：BMJ open

authors： Byrne EM,Kirk KM,Medland SE,McGrath JJ,Colodro-Conde L,Parker R,Cross S,Sullivan L,Statham DJ,Levinson DF,Licinio J,Wray NR,Hickie IB,Martin NG

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:To analyse the completeness in GallRiks of the follow-up frequency in relation to the intraoperative and postoperative outcome. DESIGN:Population-based register study. SETTING:Data from the national Swedish Registry for Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography (ERCP), GallRiks. ...

journal_title：BMJ open

authors： Enochsson L,Blohm M,Sandblom G,Jonas E,Hallerbäck B,Lundell L,Österberg J

更新日期：2018-01-23 00:00:00

abstract：INTRODUCTION:Chronic lower back pain (CLBP) is a major healthcare problem with wide ranging effects. It is a priority for appropriate management of CLBP to get individuals back to work as early as possible. Interventions that identify biopsychosocial barriers to recovery have been observed to lead to successfully reduc...

journal_title：BMJ open

authors： Dwyer CP,Durand H,MacNeela P,Reynolds B,Hamm RM,Main CJ,O'Connor LL,Conneely S,Taheny D,Slattery BW,O'Neill C,NicGabhainn S,Murphy AW,Kropmans T,McGuire BE

更新日期：2016-05-26 00:00:00

abstract：OBJECTIVE:We aimed to estimate the gender-specific prevalence and associated factors of hypertension among elderly people in Bangladesh. DESIGN AND METHOD:We analysed data from the food security and nutrition surveillance round 2018-2019. The multistage cluster sampling method was used to select the study population. ...

journal_title：BMJ open

authors： Hanif AAM,Shamim AA,Hossain MM,Hasan M,Khan MSA,Hossaine M,Ullah MA,Sarker SK,Rahman SMM,Mitra DK,Mridha MK

更新日期：2021-01-21 00:00:00