Abstract:
BACKGROUND:The objective of this study to develop percentile curves for cardiometabolic disease markers in a population-based sample of Canadian children and youth. METHODS:The analysis used data from 6116 children and adolescents between 6 and 19 years of age who participated in the Canadian Health Measures Survey cycles 1 (2007/2009), 2 (2009/2011), and 3 (2012/2013). Total cholesterol, HDL cholesterol, and hemoglobin A1c levels as well as fasting levels of triglycerides, insulin, and homeostasis model assessment insulin resistance were measured using standardized procedures. Age- and sex-specific centiles for all markers were calculated using Cole and Green's LMS method. RESULTS:With the exception of hemoglobin A1c, all markers showed age- and sex-related differences during childhood and adolescence. CONCLUSIONS:We have developed centile curves for cardiometabolic disease markers in Canadian children and adolescents and demonstrated age and sex differences that should be considered when evaluating these markers in this age group.
journal_name
BMC Pediatrjournal_title
BMC pediatricsauthors
Ata N,Maguire B,Hamilton DC,Kuhle Sdoi
10.1186/s12887-018-1289-2subject
Has Abstractpub_date
2018-09-28 00:00:00pages
314issue
1issn
1471-2431pii
10.1186/s12887-018-1289-2journal_volume
18pub_type
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