Abstract:
BACKGROUND:Serious thromboembolic events connected with rFVIIa therapy in hemophilia patients are rare. Only three cases are reported in children, all of them with hemophilia A. CASE PRESENTATION:We present unique case of patient with hemophilia B and high titer inhibitors to coagulation FIX, who developed severe renal damage due to thromboembolic event during rFVIIa therapy, associated with unsuspected renovascular anomalies. CONCLUSION:Caution is necessary if hematuria B requires administration of rFVIIa. US color doppler renal imaging before and after drug administration should be sufficient as an early warning.
journal_name
BMC Pediatrjournal_title
BMC pediatricsauthors
Milošević D,Bilić E,Batinić D,Poropat M,Štern-Padovan R,Galić S,Turudić Ddoi
10.1186/s12887-014-0315-2subject
Has Abstractpub_date
2014-12-17 00:00:00pages
315issn
1471-2431pii
s12887-014-0315-2journal_volume
14pub_type
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