Efficacy of nanocurcumin supplementation on insulin resistance, lipids, inflammatory factors and nesfatin among obese patients with non-alcoholic fatty liver disease (NAFLD): a trial protocol.

abstract：INTRODUCTION:Gestational diabetes mellitus (GDM) is a state of glucose intolerance with onset during pregnancy. GDM carries prenatal and perinatal risks as well as long-term risks for the mother and her child. GDM may be involved in the foetal programming of long-term cardiovascular health. However, evidence is sparse ...

journal_title：BMJ open

authors： Di Bernardo S,Mivelaz Y,Epure AM,Vial Y,Simeoni U,Bovet P,Estoppey Younes S,Chiolero A,Sekarski N,MySweetHeart Research Group.

更新日期：2017-11-14 00:00:00

abstract：OBJECTIVES:To systematically assess registration details of ongoing randomised controlled trials (RCTs) targeting 10 common chronic conditions and registered at ClinicalTrials.gov and to determine the prevalence of (1) trial records excluding patients with concomitant chronic condition(s) and (2) those specifically tar...

journal_title：BMJ open

authors： Buffel du Vaure C,Dechartres A,Battin C,Ravaud P,Boutron I

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVES:Computer-administered cognitive-behavioural therapy (CCBT) may be a promising treatment for adolescents with depression, particularly due to its increased availability and accessibility. The feasibility of delivering a randomised controlled trial (RCT) comparing a CCBT program (Stressbusters) with an attenti...

journal_title：BMJ open

authors： Wright B,Tindall L,Littlewood E,Allgar V,Abeles P,Trépel D,Ali S

更新日期：2017-01-27 00:00:00

abstract：OBJECTIVES:Understanding patients' preferences for treatment is crucial to provision of good care and shared decisions, especially when more than one treatment option exists for a given condition. One such condition is infection of the area around the prosthesis after hip replacement, which affects between 0.4% and 3% ...

journal_title：BMJ open

authors： Carroll FE,Gooberman-Hill R,Strange S,Blom AW,Moore AJ

更新日期：2020-01-21 00:00:00

abstract：OBJECTIVES:Domestic violence (DV) is hazardous to survivors' health, from injuries sustained and from resultant chronic physical and mental health problems. Support from friends and relatives is significant in the lives of DV survivors; research shows associations between positive support and the health, well-being and...

journal_title：BMJ open

authors： Gregory A,Feder G,Taket A,Williamson E

更新日期：2017-03-24 00:00:00

abstract：OBJECTIVES:Multiple personal and work-related factors influence medical trainees' career decision-making. The relative value of these diverse factors is under-researched, yet this intelligence is crucially important for informing medical workforce planning and retention and recruitment policies. Our aim was to investig...

journal_title：BMJ open

authors： Scanlan GM,Cleland J,Johnston P,Walker K,Krucien N,Skåtun D,NHS Education for Scotland.

更新日期：2018-03-12 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) affects 10% of patients undergoing cardiac surgery and is an independent risk factor for all-cause mortality, ischaemic stroke and heart failure. Surgical AF ablation has been shown to significantly improve maintenance of sinus rhythm, however, small to medium size trials conducted...

journal_title：BMJ open

authors： McClure GR,Belley-Cote EP,Singal RK,Jaffer IH,Dvirnik N,An KR,Fortin G,Spence J,Whitlock RP

更新日期：2016-11-02 00:00:00

abstract：OBJECTIVES:Patients with liver disease frequently require hospitalisation with infection often the trigger. Influenza vaccination is an effective infection prevention strategy in healthy and elderly but is often perceived less beneficial in patients with liver disease. We investigated whether influenza vaccination trig...

journal_title：BMJ open

authors： Härmälä S,Parisinos CA,Shallcross L,O'Brien A,Hayward A

更新日期：2019-09-06 00:00:00

abstract：INTRODUCTION:For over a decade, enquiries into adverse perinatal outcomes have led to reports that poor collaboration has been detrimental to the safety and experience of maternity care. Despite efforts to improve collaboration, investigations into maternity care at Morecambe Bay (UK) and Djerriwarrh Health Services (A...

journal_title：BMJ open

authors： Watkins V,Nagle C,Kent B,Hutchinson AM

更新日期：2017-03-07 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the experiences of doctors and nurses caring for patients with delirium in the intensive care unit (ICU) and to describe the process of delirium management. SETTING:This study was performed in 5 ICUs located within 4 hospitals in Madrid (Spain). PARTICIPANTS:Purposeful ...

journal_title：BMJ open

authors： Palacios-Ceña D,Cachón-Pérez JM,Martínez-Piedrola R,Gueita-Rodriguez J,Perez-de-Heredia M,Fernández-de-las-Peñas C

更新日期：2016-01-29 00:00:00

abstract：INTRODUCTION:Catatonia arises from serious mental, medical, neurological or toxic conditions. The prevalence range depends on the setting and the range is anything from 7% to 63% in other countries. South African prevalence rates are currently unknown. The proposed study is a quantitative descriptive study using the Bu...

journal_title：BMJ open

authors： Zingela Z,Stroud L,Cronje J,Fink M,van Wyk S

更新日期：2020-11-06 00:00:00

abstract：PURPOSE:To design a linked hospital database using administrative and clinical information to describe associations that predict infectious diseases outcomes, including long-term mortality. PARTICIPANTS:A retrospective cohort of Townsville Hospital inpatients discharged with an International Classification of Diseases...

journal_title：BMJ open

authors： Eisen DP,McBryde ES,Vasanthakumar L,Murray M,Harings M,Adegboye O

更新日期：2020-03-18 00:00:00

abstract：INTRODUCTION:In individuals with early (indexed ≤7 days poststroke) and severe upper limb paresis (shoulder abduction and finger extension score of <5 out of 10), our objectives are to: (1) determine if biomarkers of brain structure and function collected at <1 month poststroke explain who will experience clinically im...

journal_title：BMJ open

authors： Hayward KS,Lohse KR,Bernhardt J,Lang CE,Boyd LA

更新日期：2018-11-25 00:00:00

abstract：OBJECTIVES:A central tenet of organised cancer screening is that all persons in a target population are invited. The aims of this study were to identify participant and physician factors associated with response to mailed physician-linked invitations (study 1) and to evaluate their effectiveness in an organised colorec...

journal_title：BMJ open

authors： Tinmouth J,Baxter NN,Paszat LF,Rabeneck L,Sutradhar R,Yun L

更新日期：2014-03-12 00:00:00

abstract：OBJECTIVES:Identification of patients at increased mortality risk is important in the context of increasing multimorbidity and an ageing population, to help facilitate the planning and delivery of services. The aim of this study was to examine 1-year all-cause mortality in a cohort of primary care patients in whom infl...

journal_title：BMJ open

authors： Watson J,Whiting P,Salisbury C,Banks J,Hamilton W

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:National guidance for chronic obstructive pulmonary disease (COPD) suggests that self-management support be provided for patients. Our institution has developed a standardised, manual-based, supported self-management programme: Self-Management Programme of Activity Coping and Education (SPACE for COPD(C))....

journal_title：BMJ open

authors： Bourne C,Kanabar P,Mitchell K,Schreder S,Houchen-Wolloff L,Bankart MJG,Apps L,Hewitt S,Harvey-Dunstan T,Singh SJ

更新日期：2017-07-10 00:00:00

abstract：OBJECTIVE:To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care with acute lower respiratory tract infection (ALRTI) with oral corticosteroids compared with placebo. DESIGN:Cost-consequence analysis alongside a randomised con...

journal_title：BMJ open

authors： Moure-Fernandez A,Hollinghurst S,Carroll FE,Downing H,Young G,Brookes S,May M,El-Gohary M,Harnden A,Kendrick D,Lafond N,Little P,Moore M,Orton E,Thompson M,Timmins D,Wang K,Hay AD

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVES:To assess acceptability and feasibility of trial processes and the Rehabilitation Training (ReTrain) intervention including an assessment of intervention fidelity. DESIGN:A two-group, assessor-blinded, randomised controlled trial with parallel mixed methods process and economic evaluations. SETTING:Communi...

journal_title：BMJ open

authors： Dean SG,Poltawski L,Forster A,Taylor RS,Spencer A,James M,Allison R,Stevens S,Norris M,Shepherd AI,Landa P,Pulsford RM,Hollands L,Calitri R

更新日期：2018-02-15 00:00:00

abstract：INTRODUCTION:A healthcare-associated infection (HAI) data point prevalence study (PPS) conducted in 1984 in Australian hospitals estimated the prevalence of HAI to be 6.3%. Since this time, there have been no further national estimates undertaken. In the absence of a coordinated national surveillance programme or regul...

journal_title：BMJ open

authors： Russo PL,Stewardson A,Cheng AC,Bucknall T,Marimuthu K,Mitchell BG

更新日期：2018-11-08 00:00:00

abstract：INTRODUCTION:Chronic Obstructive Pulmonary Disease (COPD)and asthma affect more than 10% of the population. Most patients use their inhaler incorrectly, mainly the elderly, thereby becoming more susceptible to poor clinical control and exacerbations. Placebo device training is regarded as one of the best teaching metho...

journal_title：BMJ open

authors： Maricoto T,Correia-de-Sousa J,Taborda-Barata L

更新日期：2019-01-28 00:00:00

abstract：OBJECTIVES:To update the current evidence base on paediatric postdischarge mortality (PDM) in developing countries. Secondary objectives included an evaluation of risk factors, timing and location of PDM. DESIGN:Systematic literature review without meta-analysis. DATA SOURCES:Searches of Medline and EMBASE were condu...

journal_title：BMJ open

authors： Nemetchek B,English L,Kissoon N,Ansermino JM,Moschovis PP,Kabakyenga J,Fowler-Kerry S,Kumbakumba E,Wiens MO

更新日期：2018-12-28 00:00:00

abstract：OBJECTIVES:Violence towards emergency department healthcare workers is pervasive and directly linked to provider wellness, productivity and job satisfaction. This qualitative study aimed to identify the cognitive and behavioural processes impacted by workplace violence to further understand why workplace violence has a...

journal_title：BMJ open

authors： Vrablik MC,Chipman AK,Rosenman ED,Simcox NJ,Huynh L,Moore M,Fernandez R

更新日期：2019-08-27 00:00:00

abstract：INTRODUCTION:A substantial minority of children who sustain a concussion suffer prolonged postconcussive symptoms. These symptoms can persist for more than 1 month postinjury and include physical, cognitive, behavioural and emotional changes. Those affected can develop significant disability, diminishing their quality ...

journal_title：BMJ open

authors： Bressan S,Takagi M,Anderson V,Davis GA,Oakley E,Dunne K,Clarke C,Doyle M,Hearps S,Ignjatovic V,Seal M,Babl FE

更新日期：2016-01-12 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with a number of comorbidities such as coronary artery disease and heart failure. While physical activity is already implemented in current international guidelines for the prevention and treatment of AF, the precise r...

journal_title：BMJ open

authors： Zacher J,Dillschnitter K,Freitag N,Kreutz T,Bjarnason-Wehrens B,Bloch W,Predel HG,Schumann M

更新日期：2020-10-31 00:00:00

abstract：INTRODUCTION:Capsular group B Neisseria meningitidis (MenB) is the most common cause of invasive meningococcal disease (IMD) in many parts of the world. A MenB vaccine directed against the polysaccharide capsule remains elusive due to poor immunogenicity and safety concerns. The vaccines licensed for the prevention of ...

journal_title：BMJ open

authors： Carr J,Plested E,Aley P,Camara S,Davis K,MacLennan JM,Gray S,Faust SN,Borrow R,Christensen H,Trotter C,Maiden MCJ,Finn A,Snape MD,‘Be on the TEAM’ investigators.

更新日期：2020-10-22 00:00:00

abstract：OBJECTIVE:Psychological distress is generally associated with poor dietary intake, but this has never been investigated among residents after a major disaster. We attempted to reveal the associations between dietary intake and non-specific mental health distress as well as traumatic symptoms among evacuees after the Gr...

journal_title：BMJ open

authors： Uemura M,Ohira T,Yasumura S,Otsuru A,Maeda M,Harigane M,Horikoshi N,Suzuki Y,Yabe H,Takahashi H,Nagai M,Nakano H,Zhang W,Hirosaki M,Abe M,Fukushima Health Management Survey Group.

更新日期：2016-07-05 00:00:00

abstract：OBJECTIVES:To identify spatial disparities and demographic characteristics of short stature, we analysed the prevalence of short stature collected in a nationwide health survey. SETTINGS:Data were obtained from the 2014 Chinese National Survey on Students Constitution and Health (a cross-sectional study of China). Par...

journal_title：BMJ open

authors： Ma J,Pei T,Dong F,Dong Y,Yang Z,Chen J,Guo S,Zhao Q,Wang S,Ma J,Zhang Z

更新日期：2019-07-16 00:00:00

abstract：OBJECTIVE:To quantify general practitioners' (GPs) sensitivity to anxiety disorders (ADs) when confronted with the range of symptoms common to children with ADs. Also, to explore GPs' conscious preferences and implicit tendencies for referral of children with ADs to mental healthcare. DESIGN AND SETTING:In a cross-sec...

journal_title：BMJ open

authors： Aydin S,Crone MR,Siebelink BM,Vermeiren RRJM,Numans ME,Westenberg PM

更新日期：2020-04-15 00:00:00

abstract：INTRODUCTION:To realise universal health coverage in an ageing society, adequate provision of appropriately trained human resources is essential. The nurse practitioner (NP) is an autonomous and independent, advanced practice nurse capable of providing treatment and care that can be substituted for some aspects of a me...

journal_title：BMJ open

authors： Kanda M,Ota E,Fukuda H,Miyauchi S,Gilmour S,Kono Y,Nakagama E,Murashima S,Shibuya K

更新日期：2015-06-23 00:00:00

abstract：BACKGROUND:The Baby Friendly Hospital Initiative (BFHI) is a practice guideline for healthcare providers to promote breastfeeding and increase breastfeeding rates. OBJECTIVE:This study aimed to examine reported experiences and views on breastfeeding of women using prenatal and postnatal services, and opinions of staff...

journal_title：BMJ open

authors： Mosher C,Sarkar A,Hashem AA,Hamadah RE,Alhoulan A,AlMakadma YA,Khan TA,Al-Hamdani AK,Senok A

更新日期：2016-12-16 00:00:00