Abstract：
BACKGROUND:Adverse childhood experiences (ACE) have been previously linked to quality of life, health conditions, and life expectancy in adulthood. Less is known about the potential mechanisms which mediate these associations. This study examined how ACE influences adult health-related quality of life (HRQoL) in a low-income community in Florida. METHODS:A community-based participatory needs assessment was conducted from November 2013 to March 2014 with 201 residents of Tampa, Florida, USA. HRQoL was measured by an excessive number of unhealthy days experienced during the previous 30-day window. Mediation analyses for dichotomous outcomes were conducted with logistic regression. Bootstrapped confidence intervals were generated for both total and specific indirect effects. RESULTS:Most participants reported 'good to excellent health' (76%) and about a fourth reported 'fair to poor health' (24%). The mean of total unhealthy days was 9 days per month (SD ± 10.5). Controlling for demographic and neighborhood covariates, excessive unhealthy days was associated with ACE (AOR = 1.23; 95% CI: 1.06, 1.43), perceived stress (AOR = 1.07; 95% CI: 1.03, 1.10), and sleep disturbance (AOR = 8.86; 3.61, 21.77). Mediated effects were significant for stress (β = 0.08) and sleep disturbances (β = 0.11) as they related to the relationship between ACE and excessive unhealthy days. CONCLUSION:ACE is linked to adult HRQoL. Stress and sleep disturbances may represent later consequences of childhood adversity that modulate adult quality of life.
journal_name
Health Qual Life Outcomesjournal_title
Health and quality of life outcomesauthors
Salinas-Miranda AA,Salemi JL,King LM,Baldwin JA,Berry EL,Austin DA,Scarborough K,Spooner KK,Zoorob RJ,Salihu HMdoi
10.1186/s12955-015-0323-4subject
Has Abstractpub_date
2015-08-11 00:00:00pages
123issn
1477-7525pii
10.1186/s12955-015-0323-4journal_volume
13pub_type
杂志文章abstract：INTRODUCTION:China is a country facing the "double burden" of both obesity and underweight. The objective of this study was to explore the relationship between body mass index (BMI) and health-related quality of life (HRQOL) in adults from Shaanxi Province. METHODS:The data were derived from the fifth Health Service S...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-015-0347-9
更新日期：2015-09-23 00:00:00
abstract：BACKGROUND:This study aimed to investigate the prevalence of abdominal obesity and its association with the health-related quality of life (HRQOL) in a randomly selected Chinese sample. METHODS:A population-based sample of 3,600 residents aged 18-80 years was selected randomly from 5 Chinese cities. Demographic inform...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-12-100
更新日期：2014-06-13 00:00:00
abstract：BACKGROUND:Restless legs syndrome (RLS) is a chronic disorder with substantial impact on quality of life similar to that seen in diabetes mellitus or osteoarthritis. Little is known about the psychological characteristics of RLS patients although psychological factors may contribute to unfavourable treatment outcome. ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章,多中心研究
doi：10.1186/1477-7525-9-73
更新日期：2011-09-20 00:00:00
abstract：BACKGROUND:NAFLD impacts patient reported outcomes (PROs). Our aim was to assess the impact of NAFLD on patients' HRQOL. METHODS:National Health and Nutrition Examination Survey (NHANES) 2001-2011 data were used to identify adult patients with NAFLD [Fatty Liver Index (FLI) > 60 in absence of other liver disease and e...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-016-0420-z
更新日期：2016-02-09 00:00:00
abstract：BACKGROUND:Bone metastases are a common painful and debilitating consequence of castration-resistant prostate cancer (CPRC). Bone pain may predict patients' prognosis and there is a need to further explore CRPC patients' experiences of bone pain in the overall context of disease pathology. Due to the subjective nature ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-9-88
更新日期：2011-10-12 00:00:00
abstract：BACKGROUND:Global research shows a clear transition in health outcomes over the past two decades where improved survival was accompanied by lower health related quality of life (HRQoL) as measured by morbidity and disability. These trends suggest the need to better understand changes in population HRQoL. This paper com...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-014-0113-4
更新日期：2014-08-05 00:00:00
abstract：BACKGROUND:Endometriosis is one of the most common causes of infertility. The causes of the disease and its definitive treatments are still unclear. Moreover, Anti-Mullerian Hormone (AMH) is a glycoprotein dimer that is a member of the transient growth factors family. This research work aimed to identify the effect of ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章,meta分析
doi：10.1186/s12955-020-01561-3
更新日期：2020-09-24 00:00:00
abstract：BACKGROUND:The primary aim of rheumatoid arthritis (RA) treatment is to induce remission, the absence of disease activity. The objective of this study was to explore the association between clinical endpoints used to gauge RA treatment efficacy and patient-reported outcomes of health-related quality of life, fatigue, a...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1186/1477-7525-12-31
更新日期：2014-03-05 00:00:00
abstract：PURPOSE:The present study aimed to determine the effect of demographic characteristics, occupation, anthropometric indices, and leisure-time physical activity levels on coronary risk and health-related quality of life among military police officers from the State of Santa Catarina, Brazil. METHODS:The sample included ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-12-60
更新日期：2014-04-27 00:00:00
abstract：BACKGROUND:The EQ-5D-5 L and the SF-12 are the most commonly used generic measures of health-related quality of life among people with arthritis. However, there is little evidence on the extent to which the individual dimensions and domains of these instruments perform among this population. The objective was to examin...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-019-1129-6
更新日期：2019-04-17 00:00:00
abstract：BACKGROUND:Perceived dental health has shown to have a significant predictive effect on overall health perception and life satisfaction. Thus, it seems plausible that Health Related Quality of Life (HRQOL) measures are associated with Oral Health Related Quality of Life (OHRQOL) dimensions in Nepalese context as well. ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-020-01512-y
更新日期：2020-07-31 00:00:00
abstract：BACKGROUND:Dental disease and treatment experience can negatively affect the oral health related quality of life (OHRQL) of preschool aged children and their caregivers. Currently no valid and reliable instrument is available to measure these negative influences in very young children. The objective of this research wa...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-5-6
更新日期：2007-01-30 00:00:00
abstract：BACKGROUND:To date, reliable and comprehensive health-related quality of life data for patients with relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL) have not been collected in clinical trials of the disease, and no utility studies have been published. The purpose of this study was to define and va...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-015-0377-3
更新日期：2015-11-16 00:00:00
abstract：BACKGROUND:Rural-to-urban female migrant workers have a lower quality of life compared to the general population. Improving these conditions remains highly challenging. This paper reports the health-related quality of life (HRQoL) of the female migrant workers in an educational project. METHODS:In this before-and-afte...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-11-123
更新日期：2013-07-23 00:00:00
abstract：BACKGROUND:Poststroke fatigue is a persistent and distressing symptom among stroke survivors. In this study, we investigated the reliability and validity of a vertical numerical rating scale supplemented with a faces rating scale (NRS-FRS) in measuring poststroke fatigue. METHODS:The fatigue intensity of 106 individua...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-015-0290-9
更新日期：2015-06-30 00:00:00
abstract：BACKGROUND:There are very few studies about general quality of life parameters, standards for the description of health status and comparison with general population data on patients with Hereditary hemorrhagic telangiectasia (HHT), a rare disease in which epistaxis is a cardinal symptom. PURPOSE:To assess the quality...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-017-0586-z
更新日期：2017-01-23 00:00:00
abstract：BACKGROUND:Few epidemiologic studies have assessed health-related quality of life (HRQL) of asthma patients from a general population and it is unclear which instrument is best suitable for this purpose. We investigated the validity of the Asthma Quality of Life Questionnaire (AQLQ) and the SF-36 completed by individua...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-6-15
更新日期：2008-02-15 00:00:00
abstract：BACKGROUND:There are very few reliable and valid measures in Japan assessing health-related quality of life (HRQOL) in children with cancer. The present study aimed to develop a Japanese version of the Minneapolis-Manchester Quality of Life Survey of Health Adolescent Form (MMQL-AF), which is a measure for assessing th...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-014-0127-y
更新日期：2014-08-15 00:00:00
abstract：BACKGROUND:The Well-being Questionnaire (W-BQ) was designed to measure psychological well-being in people with diabetes. This study aimed to develop a Japanese version and a short form of the W-BQ. METHODS:A linguistic validation process produced a preliminary Japanese version of the 22-item W-BQ, which was distribute...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-4-40
更新日期：2006-07-03 00:00:00
abstract：BACKGROUND:The Endometriosis Symptom Diary (ESD) and Endometriosis Impact Scale (EIS) are patient-reported outcome measures developed to evaluate efficacy in clinical trials and clinical practice. The ESD is a daily electronic diary assessing symptom severity; the EIS is a weekly electronic diary assessing symptom impa...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-020-01579-7
更新日期：2021-01-06 00:00:00
abstract：BACKGROUND:The presence of multiple chronic conditions is associated with lower health related quality of life (HRQOL). Disease severity also influences HRQOL. To analyse the effects of all possible combinations of single diseases along with their severity on HRQOL seems cumbersome. Grouping diseases and their severity...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-5-52
更新日期：2007-08-06 00:00:00
abstract：BACKGROUND:The European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 is a core questionnaire designed to evaluate health-related quality of life (HRQoL) of cancer patients participating in international clinical trials. It is available in several languages including Danish. The EORTC QLQ-TC26 is a ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-018-0954-3
更新日期：2018-06-18 00:00:00
abstract：PURPOSE:To develop an algorithm for mapping the Functional Assessment of Cancer Therapy-Breast (FACT-B) to the 5-level EuroQoL Group's 5-dimension questionnaire (EQ-5D-5L) utility index. METHODS:A survey of 238 breast cancer patients in Singapore was conducted. Models using various regression methods with or without r...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-014-0180-6
更新日期：2014-12-12 00:00:00
abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have poor health-related quality of life (HRQoL). The association of CKD-related complications such as anemia and mineral and bone disorders (MBD) with HRQoL in pre-dialysis patients is not well-studied. As such, this study aimed to determine the association of anem...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-016-0477-8
更新日期：2016-06-24 00:00:00
abstract：OBJECTIVE:End-stage renal disease (ESRD) leads to renal replacement therapy and certainly has an impact on patients' health-related quality of life (HRQoL). This study aimed to review and compare the HRQoL between peritoneal dialysis (PD) and hemodialysis (HD) patients using the 36-Item Short Form Health Survey (SF-36)...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章,meta分析
doi：10.1186/s12955-020-01449-2
更新日期：2020-06-18 00:00:00
abstract：BACKGROUND:Frailty remains an elusive concept despite many efforts to define and measure it. The difficulty in translating the clinical profile of frail elderly people into a quantifiable assessment tool is due to the complex and heterogeneous nature of their health problems. Viewing frailty as a 'latent vulnerability'...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-8-123
更新日期：2010-10-28 00:00:00
abstract：BACKGROUND:Although multiple language versions of health-related quality of life instruments are often used interchangeably in clinical research, the measurement equivalence of these versions (especially using alphabet vs pictogram-based languages) has rarely been assessed. We therefore investigated the measurement equ...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-1-7
更新日期：2003-04-17 00:00:00
abstract：BACKGROUND:The 14-item Treatment Satisfaction Questionnaire for Medication (TSQM) Version 1.4 is a reliable and valid instrument to assess patients' satisfaction with medication, providing scores on four scales--side effects, effectiveness, convenience and global satisfaction. In naturalistic studies, administering the...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-7-36
更新日期：2009-04-27 00:00:00
abstract：BACKGROUND:The Musculoskeletal Health Questionnaire (MSK-HQ) has been developed to measure musculoskeletal health status across musculoskeletal conditions and settings. However, the MSK-HQ needs to be further evaluated across settings and different languages. OBJECTIVE:The objective of the study was to evaluate and co...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/s12955-020-01455-4
更新日期：2020-06-23 00:00:00
abstract：BACKGROUND:Treatment objectives for dyspepsia include improvements in both symptoms and health-related quality of life (HRQoL). There is a lack of disease-specific instruments measuring HRQoL in South East Asian dyspeptics. OBJECTIVES:To validate English and locally translated version of the Short-Form Nepean Dyspepsi...
journal_title：Health and quality of life outcomes
pub_type： 杂志文章
doi：10.1186/1477-7525-7-45
更新日期：2009-05-23 00:00:00
