Abstract:
BACKGROUND:Reactivation of latent varicella zoster virus, partly due to age-related immunosenescence and immunosuppressive conditions, results in herpes zoster (HZ) and its associated complications. The management of the most important complication, post-herpetic neuralgia (PHN), is challenging, particularly in the elderly, and is generally unsatisfactory. No previous reviews have reported the incidence of HZ-associated mortality. METHODS:We carried out a systematic literature review to identify studies and databases providing data for HZ-associated mortality in adults aged ≥ 50 years in Europe. RESULTS:We identified 12 studies: Belgium (1); France (1); Germany (1); the Netherlands (2); Portugal (1); Spain (4) and England/Wales (2) and 4 databases from Europe: France; Germany and England/Wales. The incidence was available from eight studies; it was highest in those aged ≥ 95 in France (19.48/100,000). In the European (WHO) database, the overall mortality ranged from 0 to > 0.07/100,000. The age- and gender-specific HZ mortality rates from the other databases showed that while in younger age groups the HZ mortality rate was higher in males, in older patients the rate was much higher in women. The case fatality rate was 2 and 61/100,000 in those 45-65 and ≥ 65 years, respectively. A similar increase with age was seen for the hospital fatality rate; 0.6% in those 45-65 years in the UK and 7.1% in those ≥ 80 in Spain. CONCLUSIONS:Although the data were sparse and heterogeneous, HZ-associated mortality clearly increases with age. In addition, the elderly who develop HZ often have underlying diseases and are at increased risk of functional decline and loss of independence. Mortality should be taken into account in health-economics models.
journal_name
BMC Public Healthjournal_title
BMC public healthauthors
Bricout H,Haugh M,Olatunde O,Prieto RGdoi
10.1186/s12889-015-1753-ysubject
Has Abstractpub_date
2015-05-05 00:00:00pages
466issn
1471-2458pii
10.1186/s12889-015-1753-yjournal_volume
15pub_type
历史文章,杂志文章,评审abstract:BACKGROUND:High-risk HPV DNA testing has been proposed as a primary tool for cervical cancer screening (HPV-CCS) as an alternative to the Papanicolaou cytology- method. This study describes factors associated with women's intentions to attend cervical cancer screening if high-risk HPV DNA testing (HPV-CCS) was implemen...
journal_title:BMC public health
pub_type: 杂志文章
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更新日期:2016-03-02 00:00:00
abstract:BACKGROUND:Integration of oral health promotion into general health care has been highly recommended by the World Health Organization. Primary-care physicians can as part of their general health care promote and contribute to improved oral health care. Our aim was to investigate primary-care physicians' knowledge of or...
journal_title:BMC public health
pub_type: 杂志文章
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abstract:BACKGROUND:Approximately 65% of the United Arab Emirates (UAE) population are economic migrants from the low- and middle-income countries of South Asia. Emerging evidence suggests that expatriate populations from low or middle-income countries that migrate to high-income countries acculturate their lifestyle with the o...
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abstract:BACKGROUND:Common enteric pathogens that cause gastrointestinal illness are transmitted to humans through food, water or direct contact. This poses a significant concern to public health as enteric pathogens can cause disease in a large number of people, and cost a substantial amount to treat and prevent. In order to g...
journal_title:BMC public health
pub_type: 杂志文章
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journal_title:BMC public health
pub_type: 杂志文章
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abstract::An amendment to this paper has been published and can be accessed via the original article. ...
journal_title:BMC public health
pub_type: 已发布勘误
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journal_title:BMC public health
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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journal_title:BMC public health
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2008-05-28 00:00:00
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pub_type: 杂志文章
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更新日期:2018-10-16 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2012-07-16 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-08-19 00:00:00
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pub_type: 杂志文章
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更新日期:2011-01-04 00:00:00
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更新日期:2019-12-18 00:00:00
abstract:BACKGROUND:In 2006 the World Health Organization described the status of prevention of mother to child transmission (PMTCT) service implementation as unacceptable, with an urgent need for a renewed public health approach to improve access. For PMTCT to be effective it needs to be accessible, acceptable and affordable; ...
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更新日期:2010-06-21 00:00:00
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journal_title:BMC public health
pub_type: 杂志文章
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更新日期:2020-08-20 00:00:00
abstract:BACKGROUND:There are multiple adverse effects of anemia on human function, particularly on women. However, few researches are conducted on women anemia in rural Western China. This study mainly aims to investigate the levels and associated factors of maternal anemia between 2001 and 2005 in this region. METHODS:6172 a...
journal_title:BMC public health
pub_type: 杂志文章
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更新日期:2013-04-19 00:00:00
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journal_title:BMC public health
pub_type: 杂志文章
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更新日期:2015-09-19 00:00:00