Increased homocysteine levels in valproate-treated patients with epilepsy: a meta-analysis.

abstract：OBJECTIVE:Leadership is associated with organisational performance in healthcare, including quality, safety and clinical outcomes for patients. Leadership development programmes have proliferated in recent years. Nevertheless, very few have examined participant experiences in depth in order to understand which programm...

journal_title：BMJ open

authors： Curry LA,Ayedun AA,Cherlin EJ,Allen NH,Linnander EL

更新日期：2020-04-06 00:00:00

abstract：OBJECTIVES:We aimed to examine associations between markers of pubertal timing and leisure-time physical activity (LTPA) from ages 36 to 68 years in men and women from the Medical Research Council National Survey of Health and Development. STUDY DESIGN:Pubertal timing was ascertained by physicians at age 14-15 years. ...

journal_title：BMJ open

authors： Elhakeem A,Cooper R,Bann D,Kuh D,Hardy R

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Breathlessness remains a highly prevalent and distressing symptom for many patients with progressive life-limiting illnesses. Evidence-based interventions for chronic breathlessness are limited, and there is an ongoing need for high-quality research into developing management strategies for optimal palliat...

journal_title：BMJ open

authors： Watts GJ,Clark K,Agar M,Davidson PM,McDonald C,Lam LT,Sajkov D,McCaffrey N,Doogue M,Abernethy AP,Currow DC,Australian national Palliative Care Clinical Studies Collaborative (PaCCSC).

更新日期：2016-11-29 00:00:00

abstract：INTRODUCTION:Harm from catheter-associated urinary tract infections is a common, potentially avoidable, healthcare complication. Variation in catheter prevalence may exist and provide opportunity for reducing harm, yet to date is poorly understood. This study aimed to determine variation in the prevalence of urinary ca...

journal_title：BMJ open

authors： Shackley DC,Whytock C,Parry G,Clarke L,Vincent C,Harrison A,John A,Provost L,Power M

更新日期：2017-06-23 00:00:00

abstract：BACKGROUND:Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in patients with cystic fibrosis (CF). While increasingly being offered for acute pulmonary exacerbations, little is known about the efficacy in this setting. OBJECTIVES:The authors examined the...

journal_title：BMJ open

authors： Pezzulo AA,Stoltz DA,Hornick DB,Durairaj L

更新日期：2012-04-19 00:00:00

abstract：OBJECTIVES:To assess the internal consistency and construct validity of the Finnish translation of the Jenkins Sleep Scale (JSS) in a large healthy working-age population with diverse work characteristics. DESIGN:Survey-based cross-sectional cohort study. SETTING:Survey conducted by an institute of occupational healt...

journal_title：BMJ open

authors： Juhola J,Arokoski JPA,Ervasti J,Kivimäki M,Vahtera J,Myllyntausta S,Saltychev M

更新日期：2021-01-18 00:00:00

abstract：PURPOSE:Puerto Rican children experience high rates of asthma and obesity. Further, infants born in Puerto Rico are more at risk for being born prematurely compared with infants on the mainland USA. Environmental exposures from multiple sources during critical periods of child development, potentially modified by psych...

journal_title：BMJ open

authors： Manjourides J,Zimmerman E,Watkins DJ,Carpenito T,Vélez-Vega CM,Huerta-Montañez G,Rosario Z,Ayala I,Vergara C,Feric Z,Ondras M,Suh HH,Gu AZ,Brown P,Cordero JF,Meeker JD,Alshawabkeh A

更新日期：2020-07-19 00:00:00

abstract：INTRODUCTION:Reduced hip abductor strength may indirectly lead to changes in knee kinematics and functional impairment and has been reported in patients with patellofemoral pain and knee osteoarthritis (OA). Limited information is available regarding hip abductor strength following total or unicompartmental knee arthro...

journal_title：BMJ open

authors： Kvarda P,Nüesch C,Egloff C,Appenzeller-Herzog C,Mündermann A,Ismailidis P

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND:The impulse oscillometry is increasingly used for assessing the oscillatory mechanics of the respiratory system. The within-breath behaviour of the oscillatory mechanics in chronic obstructive pulmonary disease (COPD) is a well-known physiological feature. The purpose of this study was to develop a new appro...

journal_title：BMJ open

authors： Ohishi J,Kurosawa H,Ogawa H,Irokawa T,Hida W,Kohzuki M

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To estimate physical and mental health effects of the Eyjafjallajökull volcanic eruption on nearby residents. DESIGN:Cross-sectional study. SETTING:The Icelandic volcano Eyjafjallajökull erupted on 14 April 2010. The eruption lasted for about 6 weeks and was explosive, ejecting some 8 million tons of fine p...

journal_title：BMJ open

authors： Carlsen HK,Gislason T,Benediktsdottir B,Kolbeinsson TB,Hauksdottir A,Thorsteinsson T,Briem H

更新日期：2012-03-08 00:00:00

abstract：INTRODUCTION:An ageing population has become an urgent concern for Asia in recent times. In nursing homes, polypharmacy has also become a compounding issue. Deprescribing practice is an evidence-based strategy to provide a better outcome in this group of patients; however, its implementation in nursing homes is often c...

journal_title：BMJ open

authors： Kua CH,Yeo CYY,Char CWT,Tan CWY,Tan PC,Mak VS,Lee SWH,Leong IY

更新日期：2017-05-09 00:00:00

abstract：INTRODUCTION:One in four diabetes patients will develop a foot ulcer over their lifetime. The role of glycaemic control in the healing of foot ulcers in diabetes patients is not supported by randomised controlled trial (RCT) data. OBJECTIVES:To determine the feasibility of an RCT of glycaemic control with intensive in...

journal_title：BMJ open

authors： Dissanayake A,Vandal AC,Boyle V,Park D,Milne B,Grech R,Ng A

更新日期：2020-01-20 00:00:00

abstract：OBJECTIVES:To assess the scale of ethnic inequalities in severe maternal morbidity (SMM) rates and quantify the contribution of maternal characteristics to these disparities. DESIGN:Retrospective cohort study. SETTING:Whole-of-population linked administrative data from 2002 to 2015 in Western Australia. PARTICIPANTS...

journal_title：BMJ open

authors： Adane AA,Farrant BM,Marriott R,White SW,Bailey HD,Shepherd CCJ

更新日期：2020-11-04 00:00:00

abstract：OBJECTIVES:This study aimed to explore barriers to accessing care, if any, among people living with HIV/AIDS (PLHA) in two districts of Bihar. We also aimed to assess attitudes towards PLHA among healthcare providers and community members. DESIGN:This qualitative study used an exploratory study design through thematic...

journal_title：BMJ open

authors： Nair M,Kumar P,Pandey S,Harshana A,Kazmi S,Moreto-Planas L,Burza S

更新日期：2019-11-25 00:00:00

abstract：OBJECTIVES:To estimate the prevalence of and associations between anxiety, depression, post-traumatic stress disorder (PTSD), low subjective well-being (SWB), potential traumas and postmigration stress among refugees from Syria resettled in Sweden. DESIGN:A cross-sectional and population-based questionnaire study base...

journal_title：BMJ open

authors： Tinghög P,Malm A,Arwidson C,Sigvardsdotter E,Lundin A,Saboonchi F

更新日期：2017-12-29 00:00:00

abstract：OBJECTIVES:Frequent attenders (FAs) suffer more and consult general practitioners (GPs) more often for chronic physical and psychiatric illnesses, social difficulties and distress than non-FAs. However, it is unclear to what extent FAs present transient episodes of care (TECs) compared with non-FAs. DESIGN:Retrospecti...

journal_title：BMJ open

authors： Smits FT,Brouwer HJ,Schene AH,van Weert HC,Ter Riet G

更新日期：2016-12-13 00:00:00

abstract：OBJECTIVES:To investigate the variation in sugar and energy content of cakes and biscuits available in the UK. DESIGN:We carried out a cross-sectional survey in 2016 of 381 cakes and 481 biscuits available in nine main UK supermarkets. METHODS:The sugar and energy content was collected from product packaging and nutr...

journal_title：BMJ open

authors： Hashem KM,He FJ,Alderton SA,MacGregor GA

更新日期：2018-07-25 00:00:00

abstract：INTRODUCTION:Severe acute pancreatitis (AP) requiring critical care admission (ccAP) impacts negatively on long-term survival. OBJECTIVE:To document organ-specific new morbidity and identify risk factors associated with premature mortality after an episode of ccAP. DESIGN:Cohort study. SETTING:Electronic healthcare ...

journal_title：BMJ open

authors： Ventre C,Nowell S,Graham C,Kidd D,Skouras C,Mole DJ

更新日期：2018-12-14 00:00:00

abstract：OBJECTIVE:This study sought to assess knowledge of schizophrenia and help-seeking behaviour among undergraduate students of a Nigerian university. Sociodemographic predictors of correct recognition were also explored. DESIGN:The study was a cross-sectional descriptive survey. SETTING:The study was carried out at the ...

journal_title：BMJ open

authors： Aluh DO,Okonta MJ,Odili VU

更新日期：2019-09-12 00:00:00

abstract：INTRODUCTION:Up to 1 in 4 pregnancies and 1 in 20 subsequent pregnancies end in miscarriage. Despite such prevalence the psychosocial effects are often unrecognised and unsupported. In the absence of any biomedical sequelae among men such marginalisation may be intensified. Men living through multiple miscarriages may ...

journal_title：BMJ open

authors： Williams HM,Jones LL,Coomarasamy A,Topping AE

更新日期：2020-05-15 00:00:00

abstract：OBJECTIVES:To assess the association between secondhand smoke exposure and blood lead and cadmium concentration in women in South Korea. DESIGN:Population-based cross-sectional study. SETTING:South Korea (Korea National Health and Nutrition Examination Survey V). PARTICIPANTS:1490 non-smoking women who took part in ...

journal_title：BMJ open

authors： Jung SY,Kim S,Lee K,Kim JY,Bae WK,Lee K,Han JS,Kim S

更新日期：2015-07-16 00:00:00

abstract：OBJECTIVE:To examine individual, situational and organisational aspects that influence psychological impact and recovery of a patient safety incident on physicians, nurses and midwives. DESIGN:Cross-sectional, retrospective surveys of physicians, midwives and nurses. SETTING:33 Belgian hospitals. PARTICIPANTS:913 cl...

journal_title：BMJ open

authors： Van Gerven E,Bruyneel L,Panella M,Euwema M,Sermeus W,Vanhaecht K

更新日期：2016-08-31 00:00:00

abstract：INTRODUCTION:While patient and citizen engagement has been recognised as a crucial element in healthcare reform, limited attention has been paid to how best to engage seniors-the fastest growing segment of the population and the largest users of the healthcare system. To improve the healthcare services for this populat...

journal_title：BMJ open

authors： Stolee P,Elliott J,McNeil H,Boscart V,Heckman GA,Hutchinson R,Hedley M,Glouberman S,Judd M

更新日期：2015-11-03 00:00:00

abstract：INTRODUCTION:This study is a European multicentre, randomised, double-blind, placebo-controlled trial investigating the efficacy and safety of nilvadipine as a disease course modifying treatment for mild-to-moderate Alzheimer's disease (AD) in a phase III study that will run for a period of 82 weeks with a treatment pe...

journal_title：BMJ open

authors： Lawlor B,Kennelly S,O'Dwyer S,Cregg F,Walsh C,Coen R,Kenny RA,Howard R,Murphy C,Adams J,Daly L,Segurado R,Gaynor S,Crawford F,Mullan M,Lucca U,Banzi R,Pasquier F,Breuilh L,Riepe M,Kalman J,Wallin A,Borjesson A

更新日期：2014-10-09 00:00:00

abstract：INTRODUCTION:Auditory verbal hallucinations (AVH) are prevalent experiences that can induce distress and impede social functioning. While most voice hearers benefit from antipsychotic medication or cognitive-behavioural therapy, additional effective interventions are needed to reduce the burden of experiencing AVH. 'Te...

journal_title：BMJ open

authors： Jongeneel A,Scheffers D,Tromp N,Nuij C,Delespaul P,Riper H,van der Gaag M,van den Berg D

更新日期：2018-03-06 00:00:00

abstract：OBJECTIVE:We aimed to estimate the gender-specific prevalence and associated factors of hypertension among elderly people in Bangladesh. DESIGN AND METHOD:We analysed data from the food security and nutrition surveillance round 2018-2019. The multistage cluster sampling method was used to select the study population. ...

journal_title：BMJ open

authors： Hanif AAM,Shamim AA,Hossain MM,Hasan M,Khan MSA,Hossaine M,Ullah MA,Sarker SK,Rahman SMM,Mitra DK,Mridha MK

更新日期：2021-01-21 00:00:00

abstract：INTRODUCTION:In breast cancer, local tumour control is thought to be optimised by administering higher local levels of cytotoxic chemotherapy, in particular doxorubicin. However, systemic administration of higher dosages of doxorubicin is hampered by its toxic side effects. In this study, we aim to increase doxorubicin...

journal_title：BMJ open

authors： de Maar JS,Suelmann BBM,Braat MNGJA,van Diest PJ,Vaessen HHB,Witkamp AJ,Linn SC,Moonen CTW,van der Wall E,Deckers R

更新日期：2020-11-26 00:00:00

abstract：OBJECTIVE:New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess the performance of a modified blood pressure (BP) monitor and two single-le...

journal_title：BMJ open

authors： Kearley K,Selwood M,Van den Bruel A,Thompson M,Mant D,Hobbs FR,Fitzmaurice D,Heneghan C

更新日期：2014-05-02 00:00:00

abstract：OBJECTIVE:Leptin is a pleiotropic hormone associated with learning and memory via brain receptors. However, elevated plasma leptin levels may impair cognitive and memory functions. Since individual differences in memory performance affect students' ability to learn, we aimed to study the relation between leptin status ...

journal_title：BMJ open

authors： Correa-Burrows P,Blanco E,Reyes M,Castillo M,Peirano P,Algarín C,Lozoff B,Gahagan S,Burrows R

更新日期：2016-10-18 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine whether there is an association between grandparental care and loneliness, social isolation and/or the size of an individual's social network among community-based adults aged ≥40 years. METHODS:Cross-sectional data were drawn from a population-based sample of individuals...

journal_title：BMJ open

authors： Quirke E,König HH,Hajek A

更新日期：2019-12-17 00:00:00