Abstract:
INTRODUCTION:Up to 1 in 4 pregnancies and 1 in 20 subsequent pregnancies end in miscarriage. Despite such prevalence the psychosocial effects are often unrecognised and unsupported. In the absence of any biomedical sequelae among men such marginalisation may be intensified. Men living through multiple miscarriages may also find any grief or anxiety intensified by loss of hope for future parenthood, but robust qualitative studies of these experiences are limited. We aim to rectify the deficiency. METHODS AND ANALYSIS:Our qualitative study will adopt the sounds of silence framework designed by Serrant-Green to hear the voices of populations possibly marginalised. We will listen and learn from 30 to 50 men with a history of two or more miscarriages. The research participants will be recruited from a recurrent miscarriage clinic at a large tertiary hospital in England, and from advertisements to be disseminated by the project sponsor and miscarriage charities.Individual telephone interviews supported by a semistructured discussion guide will be audio-recorded, transcribed and anonymised. The transcriptions and any field notes will be interpreted by the framework method of Ritchie and Lewis embedded within the sounds of silence framework. Tentative findings will be presented to research participants in face-to-face focus group discussion, to enable member synthesis to enhance authenticity. The focus group discussion will be audio-recorded, transcribed, anonymised and similarly interpreted to contribute to our final synthesis. ETHICS AND DISSEMINATION:The protocol of this project received a favourable opinion from the West Midlands South Birmingham Research Ethics Committee (16/WM/0423). Results will be submitted for publication in peer-reviewed journals and at conferences, and disseminated via newsletters and social media of our clinical collaborators and miscarriage charities. Outputs are anticipated to inform future policy and practice in the management of multiple miscarriages. TRIAL REGISTRATION NUMBER:ISRCTN 21828561.
journal_name
BMJ Openjournal_title
BMJ openauthors
Williams HM,Jones LL,Coomarasamy A,Topping AEdoi
10.1136/bmjopen-2019-035967subject
Has Abstractpub_date
2020-05-15 00:00:00pages
e035967issue
5issn
2044-6055pii
bmjopen-2019-035967journal_volume
10pub_type
杂志文章相关文献
BMJ Open文献大全abstract:OBJECTIVES:Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant health burden. The aim of this study was to characterise patients with recently diagnosed AF and to estimate the rates of comorbidities and outcome events requiring hospitalisation in routine clinical practice. DESIGN:Pha...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003839
更新日期:2014-01-27 00:00:00
abstract:BACKGROUND:Conflicts of interest may bias the findings of systematic reviews. The objective of this methodological survey was to assess the frequency and different types of conflicts of interest that authors of Cochrane and non-Cochrane systematic reviews report. METHODS:We searched for systematic reviews using the Co...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011997
更新日期:2016-08-10 00:00:00
abstract:INTRODUCTION:Dizziness is a common symptom in general practice with a high prevalence among older adults. The most common cause of dizziness in general practice is peripheral vestibular disease. Vestibular rehabilitation (VR) is a safe and effective treatment for peripheral vestibular disease that entails specific exer...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-015479
更新日期:2017-01-20 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of biopsychosocial Self-Management Support (SMS) delivered by practice nurses in routine diabetes care. DESIGN:A pragmatic cluster-randomised controlled trial within a hybrid effectiveness-implementation study design. Practice nurses were cluster-randomised. SETTING:A regional ...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2014-007014
更新日期:2015-06-25 00:00:00
abstract:OBJECTIVE:In caregivers of urban Aboriginal children, to determine the frequency of major stressful life events, the proportion who meet criteria for resilience, and factors that are associated with resilience. DESIGN:Cross-sectional survey. SETTING:Four Aboriginal Community Controlled Health Services located in urba...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-021687
更新日期:2018-06-06 00:00:00
abstract:INTRODUCTION:Bladder cancer (BC) (including renal pelvis, ureter and urethra) is one of the most common urogenital cancers and the fourth most frequent cancer in men in the USA. In Norway, the incidence of BC has increased over the last decades. The age-standardised incidence rates per 100 000 for 2011-2015 were 53.7 i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019309
更新日期:2018-03-30 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility of an innovative peer intervention promoting healthy eating and physical activity, which purposefully selected peer facilitators according to socioeconomic status to target less-advantaged overweight receivers. SETTING:Nine high schools, two middle schools. PARTICIPANTS:One hundr...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-019731
更新日期:2018-06-22 00:00:00
abstract:OBJECTIVE:To describe a Norwegian low-threshold HIV testing service targeting men who have sex with men (MSM). DESIGN AND SETTING:After the HIV testing consultation, all users of the HIV testing service were invited to answer the study questionnaire. The study setting included the sites where testing was performed, th...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017598
更新日期:2017-10-06 00:00:00
abstract:OBJECTIVES:Placenta or placental chorangioma could be the origin site of infantile haemangioma since they share various histochemical and genetic characteristics with placental vascular tissue. The aim of the current study was to investigate the association between chorangiomas and infantile haemangiomas in singleton a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015539
更新日期:2017-09-03 00:00:00
abstract:OBJECTIVES:To understand how the uptake of an extended primary care service in the evenings and weekend varied by day of week and over time. Secondary objectives were to understand patient demographics of users of the service and how these varied by type of appointment and to core hour users. DESIGN:Observational stud...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028138
更新日期:2019-09-05 00:00:00
abstract:INTRODUCTION:Given the promising advantages of upper extremity home-based programmes in children with cerebral palsy (CP), a systematic review of the available literature on this topic is warranted. The purpose of the systematic review described in this protocol is to investigate currently available home-based occupati...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2016-013687
更新日期:2017-02-24 00:00:00
abstract:OBJECTIVES:Describe the prevalence of substance-related and addictive disorders (SRAD) in adults with intellectual and developmental disabilities (IDD) and compare the sociodemographic and clinical characteristics of adults with IDD and SRAD to those with IDD or SRAD only. DESIGN:Population-based cohort study (the Hea...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011638
更新日期:2016-09-02 00:00:00
abstract:INTRODUCTION:Binge-eating disorder (BED) was included as its own diagnostic entity in the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). An increasing number of treatment studies have been published, but an up-to-date comprehensive meta-analysis on diverse treatment approaches for B...
journal_title:BMJ open
pub_type: 杂志文章,meta分析,评审
doi:10.1136/bmjopen-2016-013655
更新日期:2017-03-29 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the association between the use of isotretinoin and the risk of depression in patients with acne. DESIGN:This was a meta-analysis in which the standardised mean difference (SMD) and the relative risk (RR) were used for data synthesis employing the random-effects model. SETTIN...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2018-021549
更新日期:2019-01-21 00:00:00
abstract:BACKGROUND:Since the Singapore Mental Health Study in 2010 which reported a 16.0% prevalence rate for current smokers and 4.5% for nicotine dependence, new anti-smoking strategies have been implemented. The aim of this study was to compare smoking trends from the 2010 study with the second Singapore Mental Health Study...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032198
更新日期:2019-10-18 00:00:00
abstract:OBJECTIVES:1) To investigate patient and healthcare provider (HCP) knowledge, attitudes and barriers to handover and healthcare communication during inpatient care. 2) To explore potential interventions for improving the storage and transfer of healthcare information. DESIGN:Qualitative study comprising 41 semi-struct...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028199
更新日期:2019-11-11 00:00:00
abstract:BACKGROUND AND OBJECTIVE:A comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns of and reasons for sick leave during pregnancy on a multinational level, focusing on medication use ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-014934
更新日期:2017-08-03 00:00:00
abstract:INTRODUCTION:Families in low-income and middle-income countries (LMICs) face multiple challenges (eg, poverty and adverse childhood experiences) that increase the risk for child mental health problems, while the context may provide them with few resources. Existing prevention-oriented parenting programmes have been sho...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026684
更新日期:2019-01-25 00:00:00
abstract:PURPOSE:The long-term goal of the Study of Mothers' and Infants' Life Events Affecting Oral Health (SMILE) birth cohort study is to identify and evaluate the relative importance and timing of critical factors that shape the oral health of young children. It will then evaluate those factors in their inter-relationship w...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-041185
更新日期:2020-10-23 00:00:00
abstract:INTRODUCTION:Depression is a common mental disorder in the elderly population, which significantly impacts their quality of life. However, correct estimates of its magnitude are not available in the elderly in India. The present systematic review and meta-analysis would attempt to estimate the prevalence of depression ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034330
更新日期:2020-05-07 00:00:00
abstract:INTRODUCTION:Maternal and perinatal death surveillance and response (MPDSR), or any related form of audit, is a systematic process used to prevent future maternal and perinatal deaths. While the existence of MPDSR policies is routinely measured, measurement and understanding of policy implementation has lagged behind. ...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2019-031328
更新日期:2019-11-27 00:00:00
abstract:OBJECTIVES:To engage children and young people with conditions that impair learning, their parents/carers and the health, education, social work and third sector professionals to identify and prioritise research questions for learning difficulties. DESIGN:Prospective surveys and consensus meeting guided by methods adv...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028780
更新日期:2019-10-30 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Macrolides have been associated with proarrhythmic properties, but the evidence is conflicting. We evaluated the risk of out-of-hospital cardiac arrest (OHCA) associated with specific macrolides in a retrospective study. Associations between specific macrolides and OHCA were examined by cond...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019997
更新日期:2018-02-23 00:00:00
abstract:INTRODUCTION:Increasing prevalence of both thinness and excess weight during childhood and adolescence is a significant public health issue because of short-term health consequences and long-term tracking of weight status. Monitoring weight status in Europe may serve to identify countries and regions where rates of the...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2017-018241
更新日期:2017-12-21 00:00:00
abstract::Objectives In 2007, the International Agency for Research on Cancer classified long-term shift work as a probable carcinogen, with the strongest evidence for breast cancer. One proposed mechanism involves night-time light exposure and decreases in melatonin, a circadian rhythmic hormone. It is hypothesised that melato...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000532
更新日期:2012-01-21 00:00:00
abstract:INTRODUCTION:Evidence from animal studies suggest that the rate of ageing may be influenced not only by genetic and lifestyle factors, but also by the prenatal environment. We have previously shown that people who were exposed to famine during early gestation performed worse on a selective attention task, which may be ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003167
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVE:We aimed to adapt, translate and validate the Chronic Liver Disease Questionnaire (CLDQ) in Malaysian patients with chronic liver diseases of various aetiologies. SETTING:Tertiary level teaching institution in Malaysia. PARTICIPANTS:The validation process involved 211 adult patients (English language n=101,...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013873
更新日期:2017-05-25 00:00:00
abstract:OBJECTIVE:To investigate whether red blood cell distribution width (RDW) is associated with the blood pressure (BP) reverse-dipper pattern in patients with hypertension. DESIGN:Cross-sectional study. SETTING:Single centre. PARTICIPANTS:Patients with essential hypertension were included in our study (n=708). The excl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010456
更新日期:2016-02-23 00:00:00
abstract:OBJECTIVE:To summarise the findings of an updated Cochrane review of interventions aimed at improving the appropriate use of polypharmacy in older people. DESIGN:Cochrane systematic review. Multiple electronic databases were searched including MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials (fro...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2015-009235
更新日期:2015-12-09 00:00:00
abstract:OBJECTIVES:To evaluate the risk profile, achievement of cardiometabolic goals, and frequency and optimal use of cardiovascular preventive therapies among nonagenarians with type 2 diabetes mellitus (T2DM). To investigate possible sex differences. DESIGN AND SETTING:A cross-sectional population study of 11 645 persons ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030344
更新日期:2019-09-20 00:00:00