Future Care Planning for patients approaching end-of-life with advanced heart disease: an interview study with patients, carers and healthcare professionals exploring the content, rationale and design of a randomised clinical trial.

abstract：INTRODUCTION:Dementia and Imagination is a multidisciplinary research collaboration bringing together arts and science to address current evidence limitations around the benefits of visual art activities in dementia care. The research questions ask: Can art improve quality of life and well-being? If it does make a diff...

journal_title：BMJ open

authors： Windle G,Newman A,Burholt V,Woods B,O'Brien D,Baber M,Hounsome B,Parkinson C,Tischler V

更新日期：2016-11-02 00:00:00

abstract：OBJECTIVE:To determine whether neuromuscular blocking agents (NMBAs) can decrease the mortality of patients with acute respiratory distress syndrome (ARDS) and improve their clinical outcomes. DESIGN:Systematic review, meta-analysis and meta-regression. DATA SOURCES:PubMed, Embase, Cochrane Library, Web of Science an...

journal_title：BMJ open

authors： Shao S,Kang H,Tong Z

更新日期：2020-11-19 00:00:00

abstract：OBJECTIVE:Animal and in vitro studies suggest that viral acute respiratory infection (VARI) can predispose to pneumococcal infection. These findings suggest that the prevention of VARI can yield additional benefits for the control of pneumococcal disease (PD). In population-based studies, however, the evidence is not i...

journal_title：BMJ open

authors： Li Y,Peterson ME,Campbell H,Nair H

更新日期：2018-04-21 00:00:00

abstract：OBJECTIVE:To quantify and characterise missed opportunities for earlier HIV diagnosis in patients diagnosed with advanced HIV. DESIGN:A retrospective observational cohort study. SETTING:A central tertiary medical centre in Israel. MEASURES:The proportion of patients with advanced HIV, the proportion of missed opport...

journal_title：BMJ open

authors： Levy I,Maor Y,Mahroum N,Olmer L,Wieder A,Litchevski V,Mor O,Rahav G

更新日期：2016-11-10 00:00:00

abstract：OBJECTIVE:To assess the sociodemographic patterning of changes in glycaemic control of patients with diabetes affected by the 2011 triple disaster in Japan (earthquake, tsunami and nuclear accident). METHODS:A retrospective cohort study was undertaken with 404 patients with diabetes at a public hospital in Minamisoma ...

journal_title：BMJ open

authors： Leppold C,Tsubokura M,Ozaki A,Nomura S,Shimada Y,Morita T,Ochi S,Tanimoto T,Kami M,Kanazawa Y,Oikawa T,Hill S

更新日期：2016-07-07 00:00:00

abstract：OBJECTIVE:To compare intrapartum and neonatal mortality in low-risk term women starting labour in midwife-led versus obstetrician-led care. STUDY DESIGN:We performed a propensity score matched study using data from our national perinatal register, completed with data from medical files. We studied women without major ...

journal_title：BMJ open

authors： Wiegerinck MMJ,van der Goes BY,Ravelli ACJ,van der Post JAM,Buist FCD,Tamminga P,Mol BW

更新日期：2018-01-05 00:00:00

abstract：OBJECTIVE:Proton pump inhibitors (PPIs) are widely used, and their use is associated with increased risk of adverse events. However, whether PPI use is associated with excess risk of death is unknown. We aimed to examine the association between PPI use and risk of all-cause mortality. DESIGN:Longitudinal observational...

journal_title：BMJ open

authors： Xie Y,Bowe B,Li T,Xian H,Yan Y,Al-Aly Z

更新日期：2017-07-04 00:00:00

abstract：OBJECTIVES:To examine the social support network type and its associations with depression and dementia among older adults in Singapore. DESIGN:This study is a cross-sectional analysis of data from the Well-being of the Singapore Elderly study. The Practitioner Assessment of Network Type was used to identify five soci...

journal_title：BMJ open

authors： Lau YW,Vaingankar JA,Abdin E,Shafie S,Jeyagurunathan A,Zhang Y,Magadi H,Ng LL,Chong SA,Subramaniam M

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:Taxing sugar-sweetened beverages (SSBs) is now advocated, and implemented, in many countries as a measure to reduce the purchase and consumption of sugar to tackle obesity. To date, there has been little consideration of the potential impact that such a measure could have if extended to other sweet foods, su...

journal_title：BMJ open

authors： Smith RD,Cornelsen L,Quirmbach D,Jebb SA,Marteau TM

更新日期：2018-04-26 00:00:00

abstract：OBJECTIVES:To investigate the feasibility of manual segmentation by users of different backgrounds in a previously developed multifeature computer-aided diagnosis (CADx) system to classify melanocytic and non-melanocytic skin lesions based on conventional digital photographic images. METHODS:In total, 347 conventional...

journal_title：BMJ open

authors： Chang WY,Huang A,Chen YC,Lin CW,Tsai J,Yang CK,Huang YT,Wu YF,Chen GS

更新日期：2015-05-03 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening illness of unknown aetiology, with no proven pharmacological treatments. There is a limited evidence base indicating that the disease negatively affects quality of life, leading to increased dependence, restrictions on daily activities ...

journal_title：BMJ open

authors： Byrne A,Sampson C,Baillie J,Harrison K,Hope-Gill B,Hubbard R,Griffiths G,Nelson A

更新日期：2013-08-07 00:00:00

abstract：OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ...

journal_title：BMJ open

authors： Staphorst MS,Benninga MA,Bisschoff M,Bon I,Busschbach JJV,Diederen K,van Goudoever JB,Haarman EG,Hunfeld JAM,Jaddoe VVW,de Jong KJM,de Jongste JC,Kindermann A,Königs M,Oosterlaan J,Passchier J,Pijnenburg MW,Reneman L,

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Community-based interventions have been found to effectively increase the implementation of alcohol management practices and reduce excessive alcohol use and alcohol-related harm at sports clubs. However, once implementation support ceases there may be a reduction in such intervention effects. Thus, ongoin...

journal_title：BMJ open

authors： McFadyen T,Wolfenden L,Kingsland M,Tindall J,Rowland B,Sherker S,Gillham K,Heaton R,Clinton-McHarg T,Lecathelinais C,Brooke D,Wiggers J

更新日期：2018-01-23 00:00:00

abstract：INTRODUCTION:Previous research shows that patients with an implanted cardioverter defibrillator (ICD) have a fourfold increased mortality risk when suffering from anxiety compared with ICD patients without anxiety. This research supports the screening of ICD patients for anxiety with the purpose of starting relevant in...

journal_title：BMJ open

authors： Berg SK,Herning M,Svendsen JH,Christensen AV,Thygesen LC

更新日期：2016-10-21 00:00:00

abstract：INTRODUCTION:Alzheimer's disease and related dementias can be considered the epidemic of the 21st century. Particularly, the predicted growth in the size of elderly populations in low-income and middle-income countries is expected to produce a dramatic surge in dementia prevalence and incidence. Although a rising burde...

journal_title：BMJ open

authors： Lee J,Banerjee J,Khobragade PY,Angrisani M,Dey AB

更新日期：2019-07-31 00:00:00

abstract：OBJECTIVES:To evaluate patient experiences of specific aspects of haemodialysis care across several countries. DESIGN:Cross-sectional survey using the Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) questionnaire. SETTING:Haemodialysis clinics within a single provider in Europe and South A...

journal_title：BMJ open

authors： Palmer SC,de Berardis G,Craig JC,Tong A,Tonelli M,Pellegrini F,Ruospo M,Hegbrant J,Wollheim C,Celia E,Gelfman R,Ferrari JN,Törok M,Murgo M,Leal M,Bednarek-Skublewska A,Dulawa J,Strippoli GF

更新日期：2014-05-19 00:00:00

abstract：OBJECTIVES:Ophthalmology units across the UK vary widely in their adoption of electronic medical records (EMR). There is a lack of evidence to show the extent and progress of EMR adoption. The aim of this study was to capture a snapshot of the current landscape of EMR use, as a baseline for comparison in future studies...

journal_title：BMJ open

authors： Lim SB,Shahid H

更新日期：2017-05-17 00:00:00

abstract：OBJECTIVE:To investigate whether two primary care activities that are framed as indicators of primary care quality (comprehensive care plans and annual reviews of physical health) influence unplanned utilisation of hospital services for people with serious mental illness (SMI). DESIGN, SETTING, PARTICIPANTS:Retrospect...

journal_title：BMJ open

authors： Ride J,Kasteridis P,Gutacker N,Kronenberg C,Doran T,Mason A,Rice N,Gravelle H,Goddard M,Kendrick T,Siddiqi N,Gilbody S,Dare CR,Aylott L,Williams R,Jacobs R

更新日期：2018-11-28 00:00:00

abstract：OBJECTIVES:To assess medical care and costs of the 3 highest prevalence lumbar disorders-non-specific low back pain (nLBP), intervertebral disc disorder (IDD) and spinal stenosis (SS)-from national billing data to provide basic information for standards of appropriate management. DESIGN:Retrospective analysis of Natio...

journal_title：BMJ open

authors： Ahn YJ,Shin JS,Lee J,Lee YJ,Kim MR,Park KB,Lee JH,Shin KM,Ha IH

更新日期：2016-09-12 00:00:00

abstract：INTRODUCTION:Cancer is a major health problem worldwide and the leading cause of death in many countries. The number of patients with cancer and socioeconomic costs of cancer continues to increase. SH003 is a novel herbal medicine consisting of Astragalus membranaceus, Angelica gigas and Trichosanthes Kirilowii Maximow...

journal_title：BMJ open

authors： Cheon C,Kang S,Ko Y,Kim M,Jang BH,Shin YC,Ko SG

更新日期：2018-08-05 00:00:00

abstract：OBJECTIVES:The aim of the study was to understand the experiences of living with multiple chronic conditions (MCC) from the perspective of community-living older adults with MCC. DESIGN:A qualitative study using an interpretive description approach. SETTING:Participants were recruited from southern Ontario, Canada. ...

journal_title：BMJ open

authors： Ploeg J,Canesi M,D Fraser K,McAiney C,Kaasalainen S,Markle-Reid M,Dufour S,Garland Baird L,Chambers T

更新日期：2019-03-20 00:00:00

abstract：OBJECTIVES:Development of medical test guidelines differs from intervention guideline development. These differences can pose unique challenges in building evidence-based recommendations to guide clinical practice. The aim of our study was to better understand these challenges, explore reasons behind them and identify ...

journal_title：BMJ open

authors： Gopalakrishna G,Leeflang MM,Davenport C,Sanabria AJ,Alonso-Coello P,McCaffery K,Bossuyt P,Langendam MW

更新日期：2016-09-16 00:00:00

abstract：INTRODUCTION:Post-traumatic stress disorder (PTSD) is a debilitating, highly prevalent condition. Current clinical practice guidelines recommend trauma-focused psychotherapy (eg, cognitive processing therapy; CPT) as the first-line treatment for PTSD. However, while these treatments show clinically meaningful symptom i...

journal_title：BMJ open

authors： Mathersul DC,Tang JS,Schulz-Heik RJ,Avery TJ,Seppälä EM,Bayley PJ

更新日期：2019-04-03 00:00:00

abstract：PURPOSE:Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of physical activity a...

journal_title：BMJ open

authors： Carvalho-E-Silva AP,Pinheiro MB,Ferreira ML,Hübscher M,Calais-Ferreira L,Ferreira PH

更新日期：2020-07-28 00:00:00

abstract：OBJECTIVES:To evaluate the readiness to implement the Falsified Medicines Directive (FMD) by community pharmacies in England. Eight secondary objectives were assessed. SETTING:Community/retail pharmacies. PARTICIPANTS:We invited pharmacists from 501 pharmacies to complete a survey. Non-contractors, non-pharmacists or...

journal_title：BMJ open

authors： Barrett R

更新日期：2020-01-09 00:00:00

abstract：OBJECTIVE:Chronic kidney disease (CKD) is often a multimorbid condition and progression to more severe disease is commonly associated with increased management requirements, including lifestyle change, more medication and greater clinician involvement. This study explored patients' and kidney care team's perspectives o...

journal_title：BMJ open

authors： Hounkpatin HO,Leydon GM,Veighey K,Armstrong K,Santer M,Taal MW,Annells P,May C,Roderick PJ,Fraser SD

更新日期：2020-12-12 00:00:00

abstract：INTRODUCTION:Delirium is very common in patients admitted to intensive care unit (ICU), and may worsen survival in these patients. Several meta-analyses have evaluated the antidelirium effects of dexmedetomidine in ICU patients, but their findings were inconsistent. Recently, several large multicentre randomised clinic...

journal_title：BMJ open

authors： Sun R,Wang S,Li S,Yang C,Zhao Y,Luo A

更新日期：2019-04-03 00:00:00

abstract：INTRODUCTION:Although studies showed that physical activity (PA) and sedentary behaviour (SB) were associated with cardiometabolic risk factors and cognitive function, both independent and combined associations among them are inconsistent. Cardiometabolic risk factors are also associated with cognitive function, but re...

journal_title：BMJ open

authors： Lv Y,Cai L,Gui Z,Zeng X,Tan M,Wan N,Lai L,Lu S,Tan W,Chen Y

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVES:This study examined patient adherence and persistence to oral bisphosphonates for the treatment of osteoporosis in real-world settings. METHODS:A systematic review was completed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Medical Literature Analysis and Retrieval Sys...

journal_title：BMJ open

authors： Fatoye F,Smith P,Gebrye T,Yeowell G

更新日期：2019-04-14 00:00:00

abstract：OBJECTIVE:Control of glycaemic, hypertension and low-density lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention of cardiovascular diseases. The current study was an audit of glycaemic, hypertension and LDL-C control among ambulant patients with T2DM in Botswa...

journal_title：BMJ open

authors： Mwita JC,Francis JM,Omech B,Botsile E,Oyewo A,Mokgwathi M,Molefe-Baikai OJ,Godman B,Tshikuka JG

更新日期：2019-07-23 00:00:00