Predictors and outcome of surgical repair of obstetric fistula at a regional referral hospital, Mbarara, western Uganda.

Abstract:

BACKGROUND:Obstetric fistula although virtually eliminated in high income countries, still remains a prevalent and debilitating condition in many parts of the developing world. It occurs in areas where access to care at childbirth is limited, or of poor quality and where few hospitals offer the necessary corrective surgery. METHODS:This was a prospective observational study where all women who attended Mbarara Regional Referral Hospital in western Uganda with obstetric fistula during the study period were assessed pre-operatively for social demographics, fistula characteristics, classification and outcomes after surgery. Assessment for fistula closure and stress incontinence after surgery was done using a dye test before discharge RESULTS:Of the 77 women who were recruited in this study, 60 (77.9%) had successful closure of their fistulae. Unsuccessful fistula closure was significantly associated with large fistula size (Odds Ratio 6 95% Confidential interval 1.46-24.63), circumferential fistulae (Odds ratio 9.33 95% Confidential interval 2.23-39.12) and moderate to severe vaginal scarring (Odds ratio 12.24 95% Confidential interval 1.52-98.30). Vaginal scarring was the only factor independently associated with unsuccessful fistula repair (Odds ratio 10 95% confidential interval 1.12-100.57). Residual stress incontinence after successful fistula closure was associated with type IIb fistulae (Odds ratio 5.56 95% Confidential interval 1.34-23.02), circumferential fistulae (Odds ratio 10.5 95% Confidential interval 1.39-79.13) and previous unsuccessful fistula repair (Odds ratio 4.8 95% Confidential interval 1.27-18.11). Independent predictors for residual stress incontinence after successful fistula closure were urethral involvement (Odds Ratio 4.024 95% Confidential interval 2.77-5.83) and previous unsuccessful fistula repair (Odds ratio 38.69 95% Confidential interval 2.13-703.88). CONCLUSIONS:This study demonstrated that large fistula size, circumferential fistulae and marked vaginal scarring are predictors for unsuccessful fistula repair while predictors for residual stress incontinence after successful fistula closure were urethral involvement, circumferential fistulae and previous unsuccessful fistula repair.

journal_name

BMC Urol

journal_title

BMC urology

authors

Kayondo M,Wasswa S,Kabakyenga J,Mukiibi N,Senkungu J,Stenson A,Mukasa P

doi

10.1186/1471-2490-11-23

subject

Has Abstract

pub_date

2011-12-07 00:00:00

pages

23

issn

1471-2490

pii

1471-2490-11-23

journal_volume

11

pub_type

杂志文章
  • Application of hyaluronic acid/carboxymethyl cellulose membrane for early continence after nerve-sparing robot-assisted radical prostatectomy.

    abstract:BACKGROUND:To assess whether application of a hyaluronic acid-carboxymethyl cellulose membrane (HA/CMC) to the prostate bed and neurovascular plate facilitated early return of continence after nerve-sparing robot-assisted radical prostatectomy (RARP). METHODS:The subjects were 183 consecutive patients with organ-confi...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-019-0458-4

    authors: Hinata N,Bando Y,Chiba K,Furukawa J,Harada K,Ishimura T,Nakano Y,Fujisawa M

    更新日期:2019-04-23 00:00:00

  • Psychometric properties of the expanded prostate cancer index composite - 26 instrument in a cohort of radical prostatectomy patients: theoretical and practical examinations.

    abstract:BACKGROUND:Recently, the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26) was recommended for the assessment of adverse effects after the treatment of prostate cancer without clear reasons. This decision encouraged us to review the questionnaire development from the UCLA Prostate Cancer Index (UCLA-PC...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-017-0302-7

    authors: Axcrona K,Nilsson R,Brennhovd B,Sørebø Ø,Fosså SD,Dahl AA

    更新日期:2017-12-02 00:00:00

  • Multi-tract percutaneous nephrolithotomy combined with EMS lithotripsy for bilateral complex renal stones: our experience.

    abstract:BACKGROUND:The treatment of bilateral complex renal stones is a tough challenge for urologists. This study aimed to evaluate the efficiency and safety of bilateral ultrasonography-guided multi-tract percutaneous nephrolithotomy (PCNL) combined with EMS lithotripsy for the treatment of such cases. METHODS:Twenty-seven ...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-017-0205-7

    authors: Liang T,Zhao C,Wu G,Tang B,Luo X,Lu S,Dong Y,Yang H

    更新日期:2017-02-28 00:00:00

  • Clinical relevance of aortic calcification in urolithiasis patients.

    abstract:BACKGROUND:The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients. METHODS:Between January 2010 and September 2014, 1221 patients with urolithiasis were treated in Oyokyo Kidney Research Institute and Hirosaki University Hospital. Among these, 287 patient...

    journal_title:BMC urology

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12894-017-0218-2

    authors: Tanaka T,Hatakeyama S,Yamamoto H,Narita T,Hamano I,Matsumoto T,Soma O,Tobisawa Y,Yoneyama T,Yoneyama T,Hashimoto Y,Koie T,Takahashi I,Nakaji S,Terayama Y,Funyu T,Ohyama C

    更新日期:2017-04-04 00:00:00

  • Antihypertensive drugs use and the risk of prostate cancer: a meta-analysis of 21 observational studies.

    abstract:BACKGROUND:Due to the lack of strong evidence to identify the relationship between antihypertensive drugs use and the risk of prostate cancer, it was needed to do a systematic review to go into the subject. METHODS:We systematically searched PubMed, Web of Science and Embase to identify studies published, through May ...

    journal_title:BMC urology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12894-018-0318-7

    authors: Cao L,Zhang S,Jia CM,He W,Wu LT,Li YQ,Wang W,Li Z,Ma J

    更新日期:2018-03-07 00:00:00

  • Laparoscopic nephrectomy for giant staghorn calculus with non-functioning kidneys: is associated unsuspected urothelial carcinoma responsible for conversion? Report of 2 cases.

    abstract:BACKGROUND:Neglected renal stones remain a major cause of morbidity in developing countries. They not only result in functional impairment of affected kidney, but also act as an important predisposing factor for development of urothelial neoplasms. It is not uncommon to miss an associated urothelial tumor in a patient ...

    journal_title:BMC urology

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2490-6-1

    authors: Shah HN,Jain P,Chibber PJ

    更新日期:2006-01-08 00:00:00

  • Adult clear cell sarcoma of the kidney: a case report.

    abstract:BACKGROUND:Clear cell sarcoma of the kidney (CCSK) in adults is extremely rare. Optimal treatment of adult patients with CCSK remains unclear. CASE PRESENTATION:A 22-year-old man presented with a 2-month history of left flank pain. A color duplex sonography revealed a hypervascular, heterogeneous renal mass. Abdominal...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-6-11

    authors: Kural AR,Onal B,Ozkara H,Cakarir C,Ayan I,Agaoglu FY

    更新日期:2006-04-03 00:00:00

  • The prostate cancer detection rates of CEUS-targeted versus MRI-targeted versus systematic TRUS-guided biopsies in biopsy-naïve men: a prospective, comparative clinical trial using the same patients.

    abstract:BACKGROUND:The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10-12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significant PCa while insignificant PCa may be overdiagnosed. The recent developments in MRI and Contrast Enh...

    journal_title:BMC urology

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12894-017-0213-7

    authors: Postema AW,Scheltema MJ,Mannaerts CK,Van Sloun RJ,Idzenga T,Mischi M,Engelbrecht MR,De la Rosette JJ,Wijkstra H

    更新日期:2017-04-05 00:00:00

  • Role of microRNA-381 in bladder cancer growth and metastasis with the involvement of BMI1 and the Rho/ROCK axis.

    abstract:BACKGROUND:Emerging evidence has noted the important participation of microRNAs (miRNAs) in several human diseases including cancer. This research was launched to probe the function of miR-381 in bladder cancer (BCa) progression. METHODS:Twenty-eight patients with primary BCa were included in this study. Cancer tissue...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-020-00775-3

    authors: Chen D,Cheng L,Cao H,Liu W

    更新日期:2021-01-06 00:00:00

  • Prenatal diagnosis of a rare form of congenital mid-ureteral stricture: a case report and literature revisited.

    abstract:BACKGROUND:Congenital mid-ureteral stricture is a rare malformation of the ureter leading to prenatal and neonatal hydronephrosis. Site characterization of the narrowing is important to optimize the surgical approach to the newborn affected by hydronephrosis. CASE PRESENTATION:We report a female EM with a rare form of...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-7-8

    authors: Brugnara M,Cecchetto M,Manfredi R,Zuffante M,Fanos V,Pietrobelli A,Zaffanello M

    更新日期:2007-06-08 00:00:00

  • The EEF1A2 gene expression as risk predictor in localized prostate cancer.

    abstract:BACKGROUND:Besides clinical stage and Gleason score, risk-stratification of prostate cancer in the pretherapeutic setting mainly relies on the serum PSA level. Yet, this is associated with many uncertainties. With regard to therapy decision-making, additional markers are needed to allow an exact risk prediction. Eukary...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-017-0278-3

    authors: Worst TS,Waldbillig F,Abdelhadi A,Weis CA,Gottschalt M,Steidler A,von Hardenberg J,Michel MS,Erben P

    更新日期:2017-09-18 00:00:00

  • Treatment of upper urinary tract stones with extracorporeal shock wave lithotripsy (ESWL) Sonolith vision.

    abstract:BACKGROUND:The aim was to retrospectively assess the results of treatment of upper urinary tract stones with the Sonolith vision manufactured by EDAP, and purchased in 2004. METHODS:The subjects were 226 Japanese patients who underwent extracorporeal shock wave lithotripsy (ESWL) alone as an initial treatment and coul...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-11-26

    authors: Nakamura K,Tobiume M,Narushima M,Yoshizawa T,Nishikawa G,Kato Y,Katsuda R,Zennami K,Aoki S,Yamada Y,Honda N,Sumitomo M

    更新日期:2011-12-12 00:00:00

  • Testicular seminoma--unusual histology and staging with sub epithelial spread of seminoma along the vas deferans.

    abstract:BACKGROUND:The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes. CASE PRESENTATION:We present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminom...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-6-5

    authors: Lockett CJ,Nandwani GM,Stubington SR

    更新日期:2006-03-01 00:00:00

  • Partial segmental thrombosis of the corpus cavernosum (PSTCC) diagnosed by contrast-enhanced ultrasound: a case report.

    abstract:BACKGROUND:Partial segmental thrombosis of the corpus cavernosum (PSTCC) is a rare disease predominantly occurring in young men. Cardinal symptoms are pain and perineal swelling. Although several risk factors are described in the literature, the exact etiology of penile thrombosis remains unclear in most cases. MRI or ...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-14-100

    authors: Sauer S,Goltz JP,Gassenmaier T,Kunz AS,Bley TA,Klein D,Petritsch B

    更新日期:2014-12-17 00:00:00

  • Expression of pS2 in prostate cancer correlates with grade and Chromogranin A expression but not with stage.

    abstract:BACKGROUND:The biological potential of prostate cancer is extremely variable. Particular interest is focused on markers not expressed in normal prostatic tissues. pS2 protein expression has been demonstrated in a range of malignant tissues in an oestrogen-independent pathway. Recently, it has been demonstrated that pS2...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-4-14

    authors: Ather MH,Abbas F,Faruqui N,Israr M,Pervez S

    更新日期:2004-12-10 00:00:00

  • Diabetic ketoacidosis complicated by emphysematous pyelonephritis: a case report and literature review.

    abstract:BACKGROUND:The management of emphysematous pyelonephritis (EPN) includes conservative medical treatment, percutaneous drainage, and surgical resection of the involved kidney. EPN with diabetic ketoacidosis(DKA) is very rare, in which the clinical management of refusing surgical drainage is inexperienced. CASE PRESENTA...

    journal_title:BMC urology

    pub_type: 杂志文章,评审

    doi:10.1186/s12894-020-0575-0

    authors: Song Y,Shen X

    更新日期:2020-01-29 00:00:00

  • Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study.

    abstract:BACKGROUND AND AIMS:It has been reported that Helicobacter pylori (HP) infection was more prevalent in infertile populations. HP infection could lead to decreased sperm parameters, and treating the HP infection could improve the quality of sperm. However, studies investigating the relationship between infertility and H...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-020-00725-z

    authors: Feng C,Lv PP,Huang CC,Yang SQ,Yao QP,Shen JM,Jin M

    更新日期:2020-11-26 00:00:00

  • Characteristics and repair outcome of patients with Vesicovaginal fistula managed in Jimma University teaching Hospital, Ethiopia.

    abstract:BACKGROUND:In Ethiopia, about 9000 fistula cases are estimated to occur every year with an incidence of 2.2/1000 women. This study was aimed to determine obstetric fistula characteristics and surgical repair outcomes among patients with fistula surgical repair. METHODS:A Hospital based cross sectional study design was...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-016-0152-8

    authors: Sori DA,Azale AW,Gemeda DH

    更新日期:2016-07-12 00:00:00

  • Penile metastasis from recurrent sarcoma in a teenager: a case report.

    abstract:BACKGROUND:Metastatic tumors of the penis are uncommon, and fewer than 500 cases have been reported since 1870. Most penile secondary tumors originate in organs of the genitourinary tract, followed by the gastrointestinal tract. Primary tumors of sarcoma origin are extremely rare. Herein, we present a teenager who had ...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-019-0511-3

    authors: Chen CF,Tang TY,Chen M,Chen LC

    更新日期:2019-09-02 00:00:00

  • Stauffer syndrome, clinical implications and knowledge gaps, does size matter? Case report.

    abstract:BACKGROUND:Stauffer Syndrome (SS) is a paraneoplastic disorder associated with renal cell carcinoma (RCC). First described by Herbert Maurice Stauffer in 1961, it is characterized by hepatic dysfunction in the absence of metastasis, and elevated alkaline phosphatase, aminotransferases and prolonged prothrombin time. In...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-020-00671-w

    authors: Chavarriaga J,Fakih N,Cataño J,Villaquiran C,Rodriguez S,Patino G

    更新日期:2020-07-20 00:00:00

  • One-stage dorsal inlay oral mucosa graft urethroplasty for anterior urethral stricture.

    abstract:BACKGROUND:Anterior urethral stricture remains a great challenge. We reported our clinical technique and results by using inlay dorsal buccal mucosal graft urethroplasty for repair of anterior urethral stricture. METHODS:From January 2005 to July 2008, 87 male patients (range from 9 to 72 years old) with anterior uret...

    journal_title:BMC urology

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2490-14-35

    authors: Liu Y,Zhuang L,Ye W,Ping P,Wu M

    更新日期:2014-05-08 00:00:00

  • LithoVue™ for renal stone therapy - a perfect fit for high volume academic centers; a retrospective evaluation of 108 cases.

    abstract:BACKGROUND:Over the last few years the number of flexible ureterorenoscopies, used for renal stone treatment, has risen steadily. This was associated with an increase in costs for maintenance and repair of the fragile ureterorenoscopes used. To overcome this problem single-use devices have been introduced to the market...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-020-00624-3

    authors: Pallauf M,Sevcenco S,Steiner C,Drerup M,Mitterberger M,Colleselli D,Lusuardi L,Kunit T

    更新日期:2020-05-18 00:00:00

  • A rare diaphragmatic ureteral herniation case report: endoscopic and open reconstructive management.

    abstract:BACKGROUND:Ureteral herniations are a rare occurrence, generally found incidentally on cross sectional imaging or during surgical intervention for unrelated processes. Several locations of ureteral herniations can occur including the inguinal, femoral, sciatic, obturator, and thoracic regions. While few reports of uret...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-017-0207-5

    authors: Lin FC,Lin JS,Kim S,Walker JR

    更新日期:2017-04-05 00:00:00

  • A meta-ethnography to understand the experience of living with urinary incontinence: 'is it just part and parcel of life?'

    abstract:BACKGROUND:Urinary incontinence (UI) is highly prevalent and affects the lives of many men and women. We aimed to conduct a qualitative evidence synthesis (QES) to explore the experience of living with UI and to develop a conceptual model that can help us to understand this experience, and the potential barriers to app...

    journal_title:BMC urology

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12894-019-0555-4

    authors: Toye F,Barker KL

    更新日期:2020-01-16 00:00:00

  • Immediate endoscopic management of complete iatrogenic anterior urethral injuries: a case series with long-term results.

    abstract:BACKGROUND:Urethral injury produces partial or complete disruption of the urethral integrity. Advances in endourology have made endoscopic management of most of these injuries feasible without greatly compromising the final result. We report our institutional experience of immediate endoscopic realignment of complete i...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-5-13

    authors: Maheshwari PN,Shah HN

    更新日期:2005-11-09 00:00:00

  • Detection of micro-metastases by flow cytometry in lymph nodes from patients with penile cancer.

    abstract:BACKGROUND:The tumor draining lymph node concept was first described in penile cancer for staging. Immunohistochemistry and histopathology evaluations are routinely used in clinical practice to examine lymph nodes for metastasis. However, these methods are time-consuming with low diagnostic accuracy and micro-metastase...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-018-0399-3

    authors: Zhang L,Hu J,Ali Zirakzadeh A,Rosvall J,Hedlund M,Hu PS,P A Wallin R,Sherif A,Winqvist O

    更新日期:2018-10-05 00:00:00

  • The surgical technique and initial outcomes of Anatolian neobladder: a novel technique of ileal neobladder after radical cystectomy.

    abstract:BACKGROUND:We describe a detailed novel step-by-step approach for creation of an ileal neobladder and compare the outcomes with standart neobladder. METHODS:Between August 2009 and January 2016, 36 consecutive patients with bladder cancer underwent radical cystectomy and orthotopic urinary diversion with an ileal neob...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-018-0406-8

    authors: Talat Z,Onal B,Cetinel B,Demirdag C,Citgez S,Dogan C

    更新日期:2018-10-26 00:00:00

  • Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis.

    abstract:BACKGROUND:CXCL12/CXCR4 transactivation of epidermal growth factor family receptors in lipid raft membrane microdomains on cell surface is thought to mediate tumor growth and subsequent development of metastatic disease. CTCE-9908 is a known inhibitor of CXCR4. Herein, we tested the efficacy of CTCE-9908 in inhibiting ...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-14-12

    authors: Wong D,Kandagatla P,Korz W,Chinni SR

    更新日期:2014-01-28 00:00:00

  • Relationship between plasma Atherogenic index and final pathology of Bosniak III-IV renal masses: a retrospective, single-center study.

    abstract:BACKGROUND:There is an increased incidence of renal cell carcinoma (RCC) in patients with metabolic syndrome who usually have high levels of serum triglyceride (TG) and low high-density lipoprotein-cholesterol (HDL-C). Plasma atherogenic index (PAI) is the logarithmic ratio of serum TG level to HDL-C and related to car...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/s12894-019-0514-0

    authors: Karabay E,Karsiyakali N,Duvar S,Tosun C,Aslan AR,Yucebas OE

    更新日期:2019-09-13 00:00:00

  • Urothelial carcinoma of the upper urinary tract diagnosed via FGFR3 mutation detection in urine: a case report.

    abstract:BACKGROUND:Upper urinary tract cancer is typically diagnosed with urine cytology and imaging techniques. These assays can be limited by sensitivity, specificity, or technical issues making some diagnoses difficult. CASE PRESENTATION:A 73-year old man presented to the clinic with a right renal pelvis filling defect tha...

    journal_title:BMC urology

    pub_type: 杂志文章

    doi:10.1186/1471-2490-12-20

    authors: Silverberg DM

    更新日期:2012-08-08 00:00:00