Abstract:
BACKGROUND:Stauffer Syndrome (SS) is a paraneoplastic disorder associated with renal cell carcinoma (RCC). First described by Herbert Maurice Stauffer in 1961, it is characterized by hepatic dysfunction in the absence of metastasis, and elevated alkaline phosphatase, aminotransferases and prolonged prothrombin time. Initial reports did not include jaundice as an inclusion criterion. We aim to report the rare SS jaundice variant in a patient with a small renal mass and review the literature to determine if the size of the renal mass could influence the development of the SS. CASE PRESENTATION:The aim of this article is to present the case of a 53-year-old male with Stauffer syndrome jaundice variant secondary to a 2.5 cm renal mass, treated with laparoscopic radical nephrectomy with complete resolution of the syndrome. CONCLUSIONS:This syndrome is yet to be fully understood, and as far as the evidence shows, size does not matter. This entity should always be in mind when encountered with a patient with liver dysfunction and jaundice with a suspicion or confirmed diagnosis of a renal mass. To date, and to our knowledge, there have been eleven reported cases of paraneoplastic cholestatic jaundice syndrome including the current case. Six cases presented in patients with small renal mases (< 4 cm), curiously there were not a laterality tendency.
journal_name
BMC Uroljournal_title
BMC urologyauthors
Chavarriaga J,Fakih N,Cataño J,Villaquiran C,Rodriguez S,Patino Gdoi
10.1186/s12894-020-00671-wsubject
Has Abstractpub_date
2020-07-20 00:00:00pages
105issue
1issn
1471-2490pii
10.1186/s12894-020-00671-wjournal_volume
20pub_type
杂志文章相关文献
BMC Urology文献大全abstract:BACKGROUND:This study describes and compares health-related quality of life (HRQOL) of prostate cancer patients who received either radical prostatectomy (nerve-sparing, nsRP, or non-nerve-sparing, nnsRP) or radiotherapy (external RT, brachytherapy, or both combined) for treatment of localised prostate cancer. METHODS...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12894-015-0025-6
更新日期:2015-04-10 00:00:00
abstract:BACKGROUND:Caveolae play a significant role in disease phenotypes such as cancer, diabetes, bladder dysfunction, and muscular dystrophy. The aim of this study was to elucidate the caveolin-1 (CAV1) protein expression in renal cell cancer (RCC) and to determine its potential prognostic relevance. METHODS:289 clear cell...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-11-25
更新日期:2011-12-07 00:00:00
abstract:BACKGROUND:In Ethiopia, about 9000 fistula cases are estimated to occur every year with an incidence of 2.2/1000 women. This study was aimed to determine obstetric fistula characteristics and surgical repair outcomes among patients with fistula surgical repair. METHODS:A Hospital based cross sectional study design was...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0152-8
更新日期:2016-07-12 00:00:00
abstract:BACKGROUND:C-C chemokine receptor type 7 (CCR7) overexpression correlated with lymphatic metastasis and poor prognosis is a major obstacle to bladder cancer treatment. Recent studies have revealed that miR-199a-5p was significantly abnormal expressed in several solid tumors and functioned as oncogene or tumor suppresso...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0181-3
更新日期:2016-11-04 00:00:00
abstract:BACKGROUND:Bladder hyperthermic intracavitary chemotherapy (HIVEC) has good effectiveness for bladder cancer, but conventional HIVEC systems lack precision and convenient application. To test the safety of a new HIVEC device (BR-TRG-II-type) in pigs and to perform a preliminary clinical trial in patients with bladder c...
journal_title:BMC urology
pub_type: 临床试验,杂志文章
doi:10.1186/s12894-019-0543-8
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Many factors including vasoconstrictor agents can interfere with wound healing process. This study aimed to compare the histopathological outcome of injection of two sympathomimetic drugs used during urologic surgery, including phenylephrine and epinephrine, on the structure of spongy tissue and urethra in a...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0483-3
更新日期:2019-06-20 00:00:00
abstract:BACKGROUND:Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a rare hereditary kidney cancer syndrome in which affected individuals are at risk of skin and uterine leiomyomatosis and kidney cancer. HLRCC-associated kidney cancer is a lethal disease with a highly aggressive behavior, and there is no standard...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0484-2
更新日期:2019-06-10 00:00:00
abstract:BACKGROUND:To explore the additive effect of urinary incontinence, in people with comorbid depression, on health related quality of life. METHODS:Males and females, 15 to 95 years (n = 3010, response rate 70.2%) were interviewed face to face in the 1998 Autumn South Australian Health Omnibus Survey. RESULTS:Self-repo...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-13-11
更新日期:2013-02-16 00:00:00
abstract:BACKGROUND:The use of ureteral access sheath (UAS) during ureteroscopy is controversial. We aimed to explore practice patterns of UAS during ureteroscopy for nephrolithiasis among endourologists worldwide. METHODS:A 15-question survey was designed using the SurveyMonkey® platform. The questions covered the background ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0489-x
更新日期:2019-07-04 00:00:00
abstract:BACKGROUND:To establish and internally validate an innovative R.I.R.S. scoring system that allows urologists to preoperatively estimate the stone-free rate (SFR) after retrograde intrarenal surgery (RIRS). METHODS:This study included 382 eligible samples from a total 573 patients who underwent RIRS from January 2014 t...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0297-0
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:CXCL12/CXCR4 transactivation of epidermal growth factor family receptors in lipid raft membrane microdomains on cell surface is thought to mediate tumor growth and subsequent development of metastatic disease. CTCE-9908 is a known inhibitor of CXCR4. Herein, we tested the efficacy of CTCE-9908 in inhibiting ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-12
更新日期:2014-01-28 00:00:00
abstract:BACKGROUND:To assess the prognostic value of the extent of positive surgical margins (PSM) following radical prostatectomy (RP) on biochemical recurrence (BR) with long-term follow-up. METHODS:This retrospective study analyzed 1275 RPs performed between January 1992 and December 2013 in two university centers in Marse...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12894-019-0470-8
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:Emerging evidence has noted the important participation of microRNAs (miRNAs) in several human diseases including cancer. This research was launched to probe the function of miR-381 in bladder cancer (BCa) progression. METHODS:Twenty-eight patients with primary BCa were included in this study. Cancer tissue...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00775-3
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:To examine the expression of type 1 plasminogen inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC), and its possible association with microvessel density (MVD), the expression of thrombospondin-1 (TSP-1), nuclear grade, tumour stage, continuously coded tumour size (CCTS) and to assess the value of ...
journal_title:BMC urology
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2490-10-20
更新日期:2010-12-03 00:00:00
abstract:BACKGROUND:Vasitis or inflammation of the vas deferens is a rare condition, and few case reports with computed tomography images have been published since 1980. CASE PRESENTATION:A 50-year-old man presented with severe right inguinal and lower abdominal pain. Initial diagnosis at the emergency department was incarcera...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0460-x
更新日期:2019-04-29 00:00:00
abstract:BACKGROUND:Increasing evidences have documented that microRNAs (miRNAs) act as oncogenes or tumor suppressors in a variety types of cancer. The discovery of tumor associated miRNAs in serum of patients gives rise to extensive investigation of circulating miRNAs in many human cancers which support the use of plasma/seru...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-50
更新日期:2014-06-23 00:00:00
abstract:BACKGROUND:Urologists frequently encounter malignant ureteral obstruction (MUO) caused by advanced urological or non-urological malignant disease, but the treatment policy is unclear. The present study examined the risk factors for predicting ureteral stent failure in patients with MUO after ureteral stent insertion an...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0346-3
更新日期:2018-05-08 00:00:00
abstract:BACKGROUND:Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occur. Our objective was to evaluate the effect of test indication, age, gender, race, and smoking statu...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0147-5
更新日期:2016-06-13 00:00:00
abstract:BACKGROUND:We evaluated the clinical outcome of low grade Ta bladder cancer followed-up for a long period using the 2004 WHO grading system. METHODS:We retrospectively reviewed 190 patients with primary, low grade Ta bladder cancer. We defined worsening progression (WP) as confirmed high grade Ta, all T1 or Tis/concom...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-5
更新日期:2014-01-08 00:00:00
abstract:BACKGROUND:The objective of this study is to determine in a case series (four patients) how calcified deposits in renal papillae are associated with the development of calcium oxalate monohydrate (COM) papillary calculi. METHODS:From the recently collected papillary calculi, we evaluated retrospectively patients, subj...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-13-14
更新日期:2013-03-11 00:00:00
abstract:BACKGROUND:Adult men with autoimmune conditions are commonly prescribed anti-tumor necrosis factor (anti-TNF) agents; however, there is a paucity of quality evidence as to their effect on male fertility (e.g. semen parameters and sperm quality). Our objective was to determine if men with autoimmune conditions are being...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00658-7
更新日期:2020-07-27 00:00:00
abstract:BACKGROUND:Neglected renal stones remain a major cause of morbidity in developing countries. They not only result in functional impairment of affected kidney, but also act as an important predisposing factor for development of urothelial neoplasms. It is not uncommon to miss an associated urothelial tumor in a patient ...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/1471-2490-6-1
更新日期:2006-01-08 00:00:00
abstract:BACKGROUND:Upper urinary tract cancer is typically diagnosed with urine cytology and imaging techniques. These assays can be limited by sensitivity, specificity, or technical issues making some diagnoses difficult. CASE PRESENTATION:A 73-year old man presented to the clinic with a right renal pelvis filling defect tha...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-12-20
更新日期:2012-08-08 00:00:00
abstract:BACKGROUND:Our understanding of early post-vasectomy recanalization is limited to histopathological studies. The objective of this study was to estimate the frequency and to describe semen analysis patterns of early recanalization after vasectomy. METHODS:Charts displaying serial post-vasectomy semen analyses were cre...
journal_title:BMC urology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2490-6-25
更新日期:2006-09-19 00:00:00
abstract:BACKGROUND:To observe the efficacy of self-help position therapy (SHPT) after holmium laser lithotripsy via flexible ureteroscopy (FURS). METHODS:From January 2010 to November 2015, 736 nephrolithiasis patients who had received FURS lithotripsy were analyzed retrospectively. In position group, 220 cases accepted SHPT ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0348-1
更新日期:2018-05-08 00:00:00
abstract:BACKGROUND:Over the last few years the number of flexible ureterorenoscopies, used for renal stone treatment, has risen steadily. This was associated with an increase in costs for maintenance and repair of the fragile ureterorenoscopes used. To overcome this problem single-use devices have been introduced to the market...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00624-3
更新日期:2020-05-18 00:00:00
abstract:BACKGROUND:Sacral neuromodulation operations have usually been performed based on 2D fluoro images. However, sacral nerve stimulation lead implantation may be challenging when the normal anatomy is confused by obesity or congenital anomalies. Thus the surgical navigation and intraoperative imaging methods could be help...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-13-48
更新日期:2013-10-16 00:00:00
abstract:BACKGROUND:Given that a deubiquitinating enzyme, ubiquitin-specific protease 2a (USP2a), regulates ubiquitination, trafficking, and degradation of EGFR, which plays a critical role in bladder cancer, in this study, we aimed to quantify the USP2a gene expression, and to determine the possibility that USP2a can be used f...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-015-0074-x
更新日期:2015-08-07 00:00:00
abstract:BACKGROUND:Although there is growing evidence of relationship between obesity and some specific stone compositions, results were inconsistent. Due to a greater relationship between metabolic syndrome and some specific stone type, obesity measured by body mass index (BMI) has limitation in determining relationship betwe...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-015-0013-x
更新日期:2015-03-14 00:00:00
abstract:BACKGROUND:Carcinoma of urinary bladder is one of the leading causes of death in India. Successful treatment of bladder cancer depends on the early detection & specific diagnostic approaches. In the present study, microsatellite instability (MSI) has been evaluated as a prognostic marker in patients with superficial ur...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-5-2
更新日期:2005-01-12 00:00:00