Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective.

Abstract:

BACKGROUND:The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. METHODS:This study was a record review of routinely-collected programme data. RESULTS:A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. CONCLUSIONS:IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.

journal_name

BMC Public Health

journal_title

BMC public health

authors

van Wyk SS,Reid AJ,Mandalakas AM,Enarson DA,Beyers N,Morrison J,Hesseling AC

doi

10.1186/1471-2458-11-544

subject

Has Abstract

pub_date

2011-07-08 00:00:00

pages

544

issn

1471-2458

pii

1471-2458-11-544

journal_volume

11

pub_type

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