Abstract:
:Published reports of 30 separate sets of analyses from 29 observational studies relating dietary intake of magnesium to blood pressure (BP) were identified through a comprehensive search using MEDLINE and BIDS-EMBASE. Three studies were prospective, 24 cross-sectional (25 reports), of which four also contained a longitudinal component, and two were obtained from baseline data in a trial. Various dietary methodologies were used: 24-h dietary recall (n = 12), food-frequency questionnaire (8), food record (7), and duplicate diet (2). Twelve reports compared magnesium intake or BP level between subgroups. Seven showed a negative association between magnesium intake and BP level, and five reported no association. From 18 of the 30 sets of analyses either a regression estimate or a Pearson correlation coefficient was reported. Many reports also allowed identification of subgroups by sex, age and race. Ninety population samples and subgroups could thus be identified from the 30 reports. All 11 Pearson-r correlation coefficients reported for systolic BP (SBP) (three significant, P < 0.05) and 10 (out of 12) Pearson-r correlation coefficients reported for diastolic BP (DBP) (four significant) were negative. Seven reports (13 subgroups for SBP, 11 subgroups for DBP) gave partial regression coefficients after adjustment; 10 (seven significant) and eight (six significant) were negative for SBP and DBP, respectively. For 13 subgroups in five papers, Pearson-r correlation coefficients were reported after adjustment for confounding factors. Eight (out of 13) showed a negative relationship for SBP and DBP. This review points to a negative association between dietary magnesium intake and BP. A systematic quantitative overview is needed to reconcile the inconsistencies of the results of individual studies and to quantify the size of such relationship.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Mizushima S,Cappuccio FP,Nichols R,Elliott Pdoi
10.1038/sj.jhh.1000641subject
Has Abstractpub_date
1998-07-01 00:00:00pages
447-53issue
7eissn
0950-9240issn
1476-5527journal_volume
12pub_type
杂志文章,meta分析abstract::The burden of Type II diabetes is growing rapidly worldwide, across high-, middle- and low-income countries. This burden is associated primarily with increased risks of macrovascular and microvascular diseases, and it is agreed that multifactorial treatment regimens are required to reduce it. ADVANCE (Action in Diabet...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1001890
更新日期:2005-06-01 00:00:00
abstract::We evaluated the relationship between renal resistive index (RRI) of the intrarenal vasculature and cardiovascular (CV) organ damage such as left ventricular hypertrophy (LVH), diastolic dysfunction and carotid atherosclerosis in a large sample of hypertensive patients. 566 hypertensive patients underwent echocardiogr...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1002145
更新日期:2007-04-01 00:00:00
abstract::A total of 930 patients have been evaluated for safety in a programme of clinical trials for lisinopril-hydrochlorothiazide combination treatment. Combination therapy with these two agents is generally well tolerated. In clinical trials, adverse experiences in patients treated with a lisinopril-hydrochlorothiazide com...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Autonomic dysfunction is implicated in prehypertension, and previous studies have suggested that therapies that improve modulation of sympathovagal balance, such as biofeedback and slow abdominal breathing, are effective in patients with prehypertension at rest. However, considering that psychophysiological stressors ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2015.27
更新日期:2016-02-01 00:00:00
abstract::To clarify the natriuretic action of endogenous atrial natriuretic peptide (ANP) in patients with essential hypertension (EHT), we examined the relationship between ANP release and urinary sodium excretion in response to hypertonic saline infusion. Plasma ANP levels increased from 13.3 +/- 2.0 pg/ml to 37.0 +/- 3.0 pg...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The present study was conducted to determine whether Valyl-Tyrosine (VY) has an antihypertensive effect on high-normal blood pressure and mild essential hypertension, as well as spontaneous hypertensive rats (SHR). A randomised double-blind placebo-controlled study was carried out on 29 volunteers. A 100-ml drink cont...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.jhh.1001065
更新日期:2000-08-01 00:00:00
abstract::In an in vivo study, spontaneously hypertensive rats (SHR) were treated with an angiotensin II (Ang II) type 1 receptor antagonist of candesartan or hydralazine. Untreated SHR progressively developed severe hypertension, and treatment with candesartan or hydralazine decreased blood pressure. Candesartan reduced left v...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1000747
更新日期:1999-01-01 00:00:00
abstract::It has been suggested that the prevalence of coronary artery disease (CAD) is steadily increasing in sub-Saharan Africa. To address this issue, we conducted a Medline search of English language articles on cardiovascular diseases-and specifically CAD in Africa- from 1966 to 1997. The prevalence of CAD and related comp...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001562
更新日期:2003-06-01 00:00:00
abstract::Established essential hypertension is characterised haemodynamically by a normal cardiac output and elevated total peripheral resistance. As hypertensive cardiovascular disease progresses, and the patient grows older, cardiac output falls and total peripheral resistance is further elevated. The activity of the renin-a...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::There is a strong association between cigarette smoking and accelerated hypertension. In mild hypertension smoking cigarettes has a distinct pressor effect and caffeine a small but more prolonged pressor action. Coffee and cigarette smoking together have an additive effect on blood pressure (BP). We have examined the ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::Syst. China Trial aimed to determine whether titrated antihypertensive treatment could reduce the risk of stroke incidence and other cardiovascular complications among 2,298 older Chinese patients (> or = 60) with isolated systolic hypertension. The data from 3 years follow-up showed that the blood pressure reduction ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract::Consistent reports indicate that hypertension is a particularly common finding in black populations. Hypertension occurs at younger ages and is often more severe in terms of blood pressure levels and organ damage than in whites, resulting in a higher incidence of cardiovascular disease and mortality. This review provi...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2017.18
更新日期:2017-08-01 00:00:00
abstract::C-reactive protein (CRP), the prototypical acute-phase reactant, is one of the most widely known biomarkers of cardiovascular disease. Circulating levels of CRP are clinically used to predict the occurrence of cardiovascular events and to aide in the selection of therapies based on more accurate risk assessment in ind...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2013.111
更新日期:2014-07-01 00:00:00
abstract::To investigate the involvement of the sympathetic nervous system and cell membrane sodium transport in hypertensive cardiac hypertrophy, we divided 51 middle-aged male patients with essential hypertension into cardiac hypertrophy and noncardiac hypertrophy groups. We then compared the plasma noradrenaline concentratio...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::We compared the effects on blood pressure (BP) of three isocaloric diets with reduced total fat and saturated fatty acid (SAFA) contents but with different proportions of monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA). Diet LF (low fat) provided 20 en% fat (7.9% SAFA, 7.8% MUFA, 3.0% PUFA); diet HP (hig...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.jhh.1000610
更新日期:1998-06-01 00:00:00
abstract::A clear relationship exists between elevated blood pressure (BP) and various manifestations of cardiovascular disease. Despite the availability of numerous treatment guidelines, hypertension remains inadequately controlled, with only a small proportion of patients achieving target BP levels. Many factors, both patient...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1002079
更新日期:2006-11-01 00:00:00
abstract::Seventeen untreated and 36 treated hypertensives aged 65 years or more were referred to our clinic because of repeated values of systolic blood pressure > or = 160 mmHg and diastolic blood pressure > or = 95 mmHg. All 53 patients underwent 24h blood pressure monitoring during their customary daily activities. Eleven (...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Both brachial blood pressure (BP) level and its variability (BPV) significantly associate with left ventricular (LV) structure and function. Recent studies indicate that aortic BP is superior to brachial BP in the association with LV abnormalities. However, it remains unknown whether aortic BPV better associate with L...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2017.37
更新日期:2017-10-01 00:00:00
abstract::The aim of this study was to assess the effect of alcohol on blood pressure and arterial compliance over 24 h in a group of volunteers, comparing the same group of subjects on two consecutive but separate days, one with alcohol intake (alcohol day) and one free of alcohol (control day). We studied 18 healthy subjects ...
journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1038/jhh.2015.19
更新日期:2016-01-01 00:00:00
abstract::Obstructive sleep apnoea (OSA) and hypertension commonly coexist. Observational studies indicate that untreated OSA is strongly associated with an increased risk of prevalent hypertension, whereas prospective studies of normotensive cohorts suggest that OSA may increase the risk of incident hypertension. Randomized ev...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2011.47
更新日期:2012-05-01 00:00:00
abstract::In a double-blind, parallel-group multicentre study in general practice, lisinopril (10-20 mg once daily) was compared with metoprolol (100-200 mg once daily) in 360 patients whose diastolic blood pressure (DBP) was in the range 91-115 mmHg despite diuretic treatment. Following a three week run-in period during which ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1991-06-01 00:00:00
abstract::A random sample of 200 East Anglian general practitioners was surveyed to establish current trends in the management of hypertension, including measurement of blood pressure (BP), patient investigation, treatment and follow-up. A total of 125 (62.5%) completed questionnaires was returned. Responses were used to assess...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::The objective of the study was to assess factors associated with treatment satisfaction among patients receiving antihypertensive therapy. A weighted cross-sectional online survey was conducted with hypertensive patients participating in a chronic disease panel in the US. Patients on monotherapy with medications from ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001899
更新日期:2005-10-01 00:00:00
abstract::A screening programme for cardiovascular risk factors in men aged 50-59 was undertaken in North Uist, and the results compared with an age- and sex-matched control group from Dundee screened as part of the Scottish Heart Health Study. Blood pressure levels were higher in the Islanders than in controls (148 +/- 20/89 +...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::Adiponectin is a hormone involved in energy homeostasis by regulating glucose and lipid metabolism. In addition, the adiponectin gene (ADIPOQ) has polymorphisms that can modulate the circulating concentration of adiponectin. Abnormal adiponectin levels have been associated with pre-eclampsia (PE); however, the influen...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2013.53
更新日期:2014-02-01 00:00:00
abstract::Epidemiological studies demonstrated that Helicobacter pylori (H. pylori) infection was associated with cardiovascular disease and its risk factors. However, the association between H. pylori infection and hypertension remained unclear. The aim of this study was to investigate the association between H. pylori infecti...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-017-0028-8
更新日期:2018-02-01 00:00:00
abstract::Unravelling the complete genetic predisposition to high blood pressure (BP) has proven to be challenging. This puzzle and the fact that coding regions of the genome account for less than 2% of the entire human DNA support the hypothesis that genetic mechanism besides coding genes are likely to contribute to BP regulat...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2014.99
更新日期:2015-08-01 00:00:00
abstract::Psychosocial work environments may adversely influence blood pressure, but the benefits of altering these factors and introducing coping resources is unclear. We examined whether changing work stressors and coping resources affect the risk of hypertension and elevated BP. A total of 13,145 workers from the Occupationa...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2016.79
更新日期:2017-05-01 00:00:00
abstract::Plasma gamma-glutamyltransferase (GGT) was suggested to reflect the level of systemic oxidative stress. Oxidative stress induces changes in arterial structure and function and contributes to the development of hypertension. Therefore, GGT may be associated with arterial remodeling and blood pressure (BP) increment, ev...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-020-0337-1
更新日期:2020-04-29 00:00:00
abstract::A neurogenic component to primary hypertension (hypertension) is now well established. Along with raised vasomotor tone and increased cardiac output, the chronic activation of the sympathetic nervous system in hypertension has a diverse range of pathophysiological consequences independent of any increase in blood pres...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2011.66
更新日期:2012-08-01 00:00:00