Some neoplasms and some hamartomatous syndromes: genetic considerations.

Abstract:

:This is the first of three articles on modern genetic concepts of a number of syndromes and disorders. About 1% of cancer mutations arise in the germline and produce a variety of neoplasms and hamartomatous syndromes. However, upward of 10-15% of all cancers have a major inherited component, although many of these are still enigmatic. The genetic basis is presented and following a review of many neoplasms and hamartomatous syndromes, the RET proto-oncogene is discussed as an example.

authors

Cohen MM Jr

doi

10.1016/s0901-5027(98)80066-0

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

363-9

issue

5

eissn

0901-5027

issn

1399-0020

journal_volume

27

pub_type

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