Effect of platelet-rich fibrin on the control of alveolar osteitis, pain, trismus, soft tissue healing, and swelling following mandibular third molar surgery: an updated systematic review and meta-analysis.

Abstract:

:The purpose of this study was to estimate the effect of platelet-rich fibrin (PRF) on the control of alveolar osteitis (AO), pain, trismus, soft tissue healing, and swelling following mandibular third molar surgery. A comprehensive search of the literature was conducted through PubMed, Embase, Web of Science, and Cochrane Library up to May 2019. Randomized controlled studies conforming to the inclusion criteria were included. The record screening and data extraction were conducted by two authors independently. The risk of bias assessment was performed according to the guidelines recommended by the Cochrane Collaboration. The quantitative analysis was performed using RevMan version 5.3. Nineteen studies were included in the systematic review and 17 studies were eligible for the meta-analysis. The use of PRF significantly reduced the incidence of AO and postoperative pain when compared to the controls (AO: relative risk 0.43, 95% confidence interval (CI) 0.28 to 0.65, Z=3.90, P<0.0001 (I2=0%); pain: day 1, standardized mean difference (SMD) -1.12, 95% CI -1.87 to -0.37, Z=2.93, P=0.003 (I2=95%); day 3, SMD -0.93, 95% CI -1.48 to -0.38, Z=3.30, P=0.001 (I2=92%); day 7, SMD -1.84, 95% CI -2.98 to -0.71, Z=3.19, P=0.001 (I2=97%)). Additionally, the result showed a better soft tissue healing when PRF was used (mean difference -0.63, 95% CI -1.08 to -0.18, Z=2.76, P=0.006 (I2=90%)). The use of PRF reduced the incidence of AO and postoperative pain following third molar surgery. Furthermore, PRF may also improve the postoperative soft tissue healing.

authors

Zhu J,Zhang S,Yuan X,He T,Liu H,Wang J,Xu B

doi

10.1016/j.ijom.2020.08.014

subject

Has Abstract

pub_date

2020-09-16 00:00:00

eissn

0901-5027

issn

1399-0020

pii

S0901-5027(20)30330-1

pub_type

杂志文章,评审
  • Periodontal healing two and four years after impacted lower third molar surgery. A comparative retrospective study.

    abstract::The long-term effects on periodontal tissues of impacted lower 3rd molar surgery have been investigated in a retrospective study comprising 51 cases. The postoperative examinations took place 2 and 4 years after the surgical treatment and included both clinical and radiographic variables. Assessments were made regardi...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(05)80077-3

    authors: Kugelberg CF

    更新日期:1990-12-01 00:00:00

  • Haemophilic pseudotumour of the mandible: report of three cases.

    abstract::A haemophilic pseudotumour is basically an encapsulated haematoma. It is an infrequent complication, estimated to affect 1-2% of severe haemophiliacs, although it has also been reported in patients with mild and moderate haemophilia. A history of trauma is reported in most cases, and the onset of symptoms varies from ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2006.10.002

    authors: Rey EA,Puia S,Bianco RP,Pinto MT

    更新日期:2007-06-01 00:00:00

  • The outcomes of conservative and surgical treatment of stage 2 bisphosphonate-related osteonecrosis of the jaws: a case series.

    abstract::The purpose of the current retrospective chart review is to describe the outcomes of conservative or surgical treatment of stage 2 bisphosphonate-related osteonecrosis of the jaws (BRONJ). 14 charts (mean patient age 69.07 ± 10.37 years) describing 19 BRONJ stage 2 sites were identified. According to the treatment pro...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijom.2012.05.012

    authors: Jabbour Z,El-Hakim M,Mesbah-Ardakani P,Henderson JE,Albuquerque R Jr

    更新日期:2012-11-01 00:00:00

  • Lower lip teratoma with ventral capillary malformation in an infant: case report and literature review.

    abstract::Teratomas are tumors that are derived from two or three of the primordial germ layers: ectoderm, mesoderm and endoderm. They arise most commonly in a midline or paraxial location from the brain to the sacral area and are most often located in the sacrococcygeal region. Head and neck teratomas are rare neoplasms and th...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijom.2009.06.018

    authors: Wang L,Chen X,Liu B

    更新日期:2009-12-01 00:00:00

  • Adenomatoid odontogenic tumor associated with calcifying epithelial odontogenic tumor.

    abstract::A case of odontogenic tumor which contained areas diagnostic for both adenomatoid odontogenic tumor and calcifying epithelial odontogenic tumor arising in the upper left anterior region in a 17-year-old Japanese female is reported. The histopathological observation suggested that the lesion represented primarily adeno...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0300-9785(86)80040-0

    authors: Takeda Y,Kudo K

    更新日期:1986-08-01 00:00:00

  • Unilateral temporalis muscle hypertrophy: case report.

    abstract::A case of unilateral temporalis muscle hypertrophy is presented. It is suggested that the aetiology of this condition is the same as that in cases of masseteric hypertrophy, and treatment is supportive only. ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(05)80422-9

    authors: Wilson PS,Brown AM

    更新日期:1990-10-01 00:00:00

  • Metastatic uterine leiomyosarcoma masquerading as a primary lesion of the masseter muscle.

    abstract::Leiomyosarcomas are malignant tumours of smooth muscle origin. These tumours are very rare in the head and neck region. We report a case of metastatic uterine leiomyosarcoma masquerading as a primary sarcoma of the masseter muscle. We highlight the importance of considering the possibility of an unrecognised primary a...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2005.08.004

    authors: Nusrath MA,Kendall CH,Avery CM

    更新日期:2006-05-01 00:00:00

  • Temporomandibular joint internal derangement type III: relationship to magnetic resonance imaging findings of internal derangement and osteoarthrosis. An intraindividual approach.

    abstract::The purpose of this study was to investigate whether in patients with a clinical unilateral temporomandibular joint (TMJ)-related finding of internal derangement type (ID)-III (disk displacement without reduction) in combination with TMJ-related pain, the intraindividual variable of 'unilateral TMJ ID-III pain' may be...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1054/ijom.2001.0068

    authors: Emshoff R,Rudisch A,Innerhofer K,Bösch R,Bertram S

    更新日期:2001-10-01 00:00:00

  • Changes in mechanical properties of poly-l-lactic acid mini-plate under functional load simulating sagittal splitting ramus osteotomy.

    abstract::The purpose of this study was to investigate how the characteristics of a poly-l-lactic acid mini-plate changed with dynamic loading in an environment with hydrolytic degradation. A mandible osteosynthesis model was prepared with specimen poly-l-lactic acid mini-plates to simulate sagittal splitting ramus osteotomy. T...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2007.09.178

    authors: Mizuhashi H,Suga K,Uchiyama T,Oda Y

    更新日期:2008-02-01 00:00:00

  • Transmucosal fixation of the fractured edentulous mandible.

    abstract::Transmucosal fixation is a new strategy for the treatment of edentulous mandibular fractures using external fixation principles within the oral cavity. The component parts of this technique are not new. External fixation, locking plates and transmucosal implants represent the foundations of this technique; the authors...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2010.10.027

    authors: Wood GA,Campbell DF,Greene LE

    更新日期:2011-05-01 00:00:00

  • A simple method for medial canthal reconstruction.

    abstract::A simple method for medical canthal wiring reconstruction with the help of a homolaterally fixed osteosynthesis plate and a metal wire is presented. This avoids transnasal wiring and gives superior control when correcting the position of the lacerated Omedial canthus. ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1054/ijom.2001.0060

    authors: Wittkampf AR,Mourits MP

    更新日期:2001-08-01 00:00:00

  • Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases.

    abstract::Central giant cell granuloma (CGCG) is a benign lesion of the jaws with a sometimes locally aggressive behaviour. The most common therapy is surgical curettage which has a high recurrence rate, especially in lesions with aggressive signs and symptoms (i.e. pain, paresthesia, root-resorption and rapid growth). Alternat...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2006.02.011

    authors: de Lange J,van den Akker HP,van den Berg H,Richel DJ,Gortzak RA

    更新日期:2006-09-01 00:00:00

  • Oral submucous fibrosis: a new concept in surgical management. Report of 100 cases.

    abstract::Oral submucous fibrosis (OSF) is a collagen disorder commonly seen in the Indian subcontinent. A series of 100 patients is presented. All lesions were biopsied. The condition was staged into four categories. Very early and early cases were treated by local injection of triamicinolone acetonide, while advanced cases we...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(05)80473-4

    authors: Khanna JN,Andrade NN

    更新日期:1995-12-01 00:00:00

  • Histopathological factors affecting nodal metastasis in tongue cancer: analysis of 94 patients in Taiwan.

    abstract::The overall prognosis for tongue cancer patients in Taiwan is unpredictable, even when patients are treated following the guidelines according to TNM stages. In order to determine the optimal treatment modality for tongue cancer in Taiwan the authors aimed to correlate histopathological parameters with neck nodal meta...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2008.07.014

    authors: Chen YW,Yu EH,Wu TH,Lo WL,Li WY,Kao SY

    更新日期:2008-10-01 00:00:00

  • Transoral approach for large pituitary adenoma using Le Fort I osteotomy with mandibulotomy. A case report.

    abstract::A patient is presented with a large pituitary adenoma that was successfully treated with a Le Fort I osteotomy in combination with mandibulotomy. ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:

    authors: Myoken Y,Sugata T,Kiriyama T,Kiya K

    更新日期:2000-04-01 00:00:00

  • The effect of simvastatin on remodelling of the alveolar bone following tooth extraction.

    abstract::Suppression of residual ridge resorption after tooth extraction is a hot spot in dental research. Recently, simvastatin was reported to influence bone turnover by stimulating bone formation. In this study, the effect of simvastatin application on residual ridge resorption following tooth extraction was investigated. S...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2007.06.018

    authors: Wu Z,Liu C,Zang G,Sun H

    更新日期:2008-02-01 00:00:00

  • Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background.

    abstract::The authors report a case of adenoid cystic carcinoma (ACC) complicated with sialolithiasis of the submandibular gland. The patient was a 43-year-old female with a history of papillotubular carcinoma of the breast almost at the same time. She had noticed a swelling in her sublingual area for 10 years, which was later ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2010.11.009

    authors: Hasegawa M,Cheng J,Maruyama S,Yamazaki M,Iida A,Takagi R,Tanaka R,Hayashi T,Saito C,Saku T

    更新日期:2011-06-01 00:00:00

  • Morbidity of anterior iliac crest and calvarial bone donor graft sites: a 1-year randomized controlled trial.

    abstract::Autogenous bone graft harvesting is still commonly considered the gold standard for the reconstruction of a severely resorbed maxillary alveolar ridge; however, the preferred donor site remains a subject of debate. This study compared the morbidity of calvarial and iliac crest donor sites after harvesting. Twenty eden...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ijom.2018.06.002

    authors: Putters TF,Wortmann DE,Schortinghuis J,van Minnen B,Boven GC,Vissink A,Raghoebar GM

    更新日期:2018-11-01 00:00:00

  • Percutaneous endoscopic gastrostomy for postoperative rehabilitation after maxillofacial tumor surgery.

    abstract::Despite the progress made in tumor and reconstructive surgery of the maxillofacial region, postoperative problems, such as malnutrition and dysfunction of the oral-oesophageal tract are still encountered. Nutrition via a nasogastric tube often complicates the rehabilitation process of these patients. Percutaneous endo...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(05)80693-9

    authors: Koehler J,Buhl K

    更新日期:1991-02-01 00:00:00

  • Effects of bone morphogenetic protein-2 on proliferation and angiogenesis in oral squamous cell carcinoma.

    abstract::Experimental data and limited patient experience suggest that rhBMP-2 can be used to regenerate bone in acquired segmental defects of the mandible. Most of these defects are caused by resection of oral squamous cell carcinoma (OSCC) and the biologic effects of rhBMP-2 on these carcinoma cells are unknown. The objectiv...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2009.11.015

    authors: Gao Q,Tong W,Luria JS,Wang Z,Nussenbaum B,Krebsbach PH

    更新日期:2010-03-01 00:00:00

  • Histologic findings and related diagnostic methods in condylar hyperactivity.

    abstract::Condylar hyperactivity (CH) is a rare condition that entails a progressive deviation and deformation of the mandible. There is no consensus regarding characteristic histopathological features or a standardized diagnostic process; thus, histopathological analysis of the condyle cannot confirm or exclude an active CH af...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijom.2020.07.001

    authors: Espinosa S,Covarrubias E,Díaz R,Díaz KT,Cafferata EA

    更新日期:2021-01-01 00:00:00

  • Inhibition of growth and increase of alkaline phosphatase activity in cultured human oral cancer cells by all-trans retinoic acid.

    abstract::In this study, the effects of all-trans retinoic acid (ATRA) on human oral cancer cells with regard to cell growth, the cell cycle, and alkaline phosphatase (ALP) activity were evaluated. Human oral cancer KB cells were treated with various concentrations of ATRA, and cell growth was then determined using the MTT viab...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2006.01.005

    authors: Xiao B,Guo J,Lou Y,Meng D,Zhao W,Zhang L,Yan C,Wang D

    更新日期:2006-07-01 00:00:00

  • Cartilaginous exostoses of the mandible.

    abstract::Although cartilaginous exostosis is considered to be the most common tumor of the skeleton, it is relatively uncommon in the jaws. The pathogenesis of the lesion is unclear. Three cases are presented and the development of the tumors from embryonic cartilage is discussed. ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(06)80034-2

    authors: Kermer C,Rasse M,Undt G,Lang S

    更新日期:1996-10-01 00:00:00

  • Demographical and clinical aspects of sports-related maxillofacial and skull base fractures in hospitalized patients.

    abstract::As many as 30% of all maxillofacial fractures (MFFs) and skull base fractures (SBFs) are reported to be sports-related. Participation in sporting activities has grown worldwide and the number of cases of sports-related injuries has also increased. The aim of this study was to evaluate the data of 3596 patients hospita...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2010.04.006

    authors: Elhammali N,Bremerich A,Rustemeyer J

    更新日期:2010-09-01 00:00:00

  • Transfusion transmitted virus (TTV) in dental patients.

    abstract::Transfusion transmitted virus (TTV) is a new DNA virus found in patients with post-transfusion hepatitis. The prevalence of this virus among dental patients has not been reported, therefore, the prevalence of TTV infection in consecutive dental inpatients was evaluated. TTV DNA was assayed by the polymerase chain reac...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1054/ijom.2000.0224

    authors: Takata Y,Kurokawa H,Fukuda J

    更新日期:2003-04-01 00:00:00

  • Changes in border movement of the mandible in skeletal Class III before and after orthognathic surgery.

    abstract::The purpose of this study was to examine the changes in border movement of the mandible before and after mandibular ramus osteotomy in patients with prognathism. The subjects were 73 patients with mandibular prognathism who underwent sagittal split ramus osteotomy (SSRO) with and without Le Fort I osteotomy. Border mo...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2013.07.740

    authors: Ueki K,Marukawa K,Moroi A,Sotobori M,Ishihara Y,Iguchi R,Kosaka A,Nakano Y,Higuchi M,Nakazawa R

    更新日期:2014-02-01 00:00:00

  • 3D Stereophotogrammetric assessment of pre- and postoperative volumetric changes in the cleft lip and palate nose.

    abstract::In cleft lip and palate patients the shape of the nose invariably changes in three dimensions (3D) due to rhinoplastic surgery. The purpose of this study was to evaluate stereophotogrammetry as a 3D method to document volumetric changes of the nose in patients with a cleft lip (CL) or cleft lip and palate (CLP) after ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2010.03.022

    authors: van Loon B,Maal TJ,Plooij JM,Ingels KJ,Borstlap WA,Kuijpers-Jagtman AM,Spauwen PH,Bergé SJ

    更新日期:2010-06-01 00:00:00

  • Midline cervical cleft. A case report.

    abstract::A case of incomplete midline cervical cleft of the upper neck is reported. It showed histological resemblance to a mature teratoma with three different germ-cell components, including cartilage, striated muscles, small salivary glands, and nerves. ...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/s0901-5027(05)80731-3

    authors: Ikuzawa M,Matsumoto K,Amino K,Sakuda M

    更新日期:1992-10-01 00:00:00

  • Removal of a self-knotted feeding jejunostomy tube in a patient with tongue base cancer.

    abstract::The knotting of an intragastric tube is a rare complication, and knotting of a feeding jejunostomy tube is rarer, and the removal or replacement of the tube is difficult. There are many reports on the removal of intragastric knotted tubes, but these methods cannot be applied for the removal of knotted feeding jejunost...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2010.04.043

    authors: Jwo SC

    更新日期:2010-09-01 00:00:00

  • Transplantation of a reverse facial artery pedicled submandibular gland in a dog.

    abstract::This study was performed to evaluate the possibility of using reverse facial artery pedicled submandibular gland transfer for treating keratoconjunctivitis sicca. A reverse facial artery pedicled submandibular gland, including the duct, from a beagle dog was transplanted into the temporal region in the same animal. 99...

    journal_title:International journal of oral and maxillofacial surgery

    pub_type: 杂志文章

    doi:10.1016/j.ijom.2008.07.013

    authors: Chen WL,Liu S,Li HG,Wang YY,Wang K

    更新日期:2008-11-01 00:00:00