Abstract：
:This study evaluated survival in 154 patients with stages II-IV oral squamous cell carcinoma (OSCC) treated with preoperative concurrent chemoradiotherapy and assessed the future use of this treatment strategy. 14 patients exhibited advanced stage II, 73 exhibited stage III and 67 exhibited stage IV. All patients received 40Gy irradiation and concurrent cisplatin-based chemotherapy in two courses. Radical surgery was undertaken after 2-6 weeks. The clinical tumour response, histopathologic regression grade, residual tumour grade (RGrade) in the primary tumour and the level of residual pN+ were associated with prognosis. 90% of patients with complete response and 73% of patients with good partial response in the primary tumour were RGrade 0 (no residual tumour cells) or RGrade 1 (viable tumour cells remained within central superficial portion). In patients with complete response in the neck, residual pN+ was only seen in levels IB (8%) and IIA (8%); the higher the level of residual pN+, the lower the survival rate (p<0.0001). This treatment strategy was excellent for stages II-IV OSCC. It may be possible to perform minimally invasive surgery in which the extent of resection in primary tumour and neck is reduced in patients who achieve good response following preoperative chemoradiotherapy.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Kirita T,Yamanaka Y,Imai Y,Yamakawa N,Aoki K,Nakagawa Y,Yagyuu T,Hasegawa Mdoi
10.1016/j.ijom.2011.12.003subject
Has Abstractpub_date
2012-04-01 00:00:00pages
421-8issue
4eissn
0901-5027issn
1399-0020pii
S0901-5027(11)01559-1journal_volume
41pub_type
杂志文章abstract：:Sentinel node navigation surgery (SNNS) has received considerable attention for its role in deciding whether to perform neck dissection in patients with early oral cancer. However, diagnostic accuracy and its intraoperative availability of results remain important concerns. First, we shortened the examination time req...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.ijom.2004.01.009
更新日期：2004-10-01 00:00:00
abstract：:The aim of this study was to compare sensitivity, specificity, accuracy and positive and negative predictive value for high-resolution ultrasonography (HR-US) in diagnosing degenerative changes, effusion and disk displacement using magnetic resonance imaging (MRI) as a reference. Over a period of 6 months, 100 patient...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2004.03.014
更新日期：2005-03-01 00:00:00
abstract：:Demineralized bone powder (DBP) has been shown to induce osteogenesis in a variety of bone defects and extra-osseous sites. Previous investigations have been carried out in animal models which are time-consuming and expensive. We studied the effect of DBP on well-established populations of osteoblast and non-osteoblas...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80085-2
更新日期：1990-12-01 00:00:00
abstract：:The aims of this study were to evaluate volumetric changes in the nasal cavity (NC) and pharyngeal airway space (PAS) after Le Fort I maxillary distraction osteogenesis (MDO) using a three-dimensional (3D) simulation program, and to determine the effects of MDO on respiratory function during sleep with polysomnography...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2014.10.021
更新日期：2015-04-01 00:00:00
abstract：:A case of intraoral molluscum contagiosum involving the right distal alveolar bridge of an immunocompetent person is reported. A review of the literature, with only five previously published cases, revealed that involvement of the oral soft tissues is rare. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2009.01.019
更新日期：2009-07-01 00:00:00
abstract：:An orbital embryonal rhabdomyosarcoma is reported. The diagnosis was delayed by several weeks due to a concurrent history of repeated trauma. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(97)80800-4
更新日期：1997-10-01 00:00:00
abstract：:A haemophilic pseudotumour is basically an encapsulated haematoma. It is an infrequent complication, estimated to affect 1-2% of severe haemophiliacs, although it has also been reported in patients with mild and moderate haemophilia. A history of trauma is reported in most cases, and the onset of symptoms varies from ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2006.10.002
更新日期：2007-06-01 00:00:00
abstract：:The purpose of this study was to compare computed tomography (CT) Hounsfield unit values of bone fragment gaps after sagittal split ramus osteotomy (SSRO) in patients with and without asymmetry, and to evaluate differences between the deviated and non-deviated sides in asymmetric patients. Thirty-two patients who unde...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2016.08.015
更新日期：2016-12-01 00:00:00
abstract：:The Le Fort I osteotomy is performed under general anaesthesia and specific haemodynamic conditions, i.e. hypotensive general anaesthesia. This study assessed the incidence of the trigeminocardiac reflex (TCR) during the different stages of the Le Fort I osteotomy. Forty-seven patients requiring a Le Fort I osteotomy ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.10.012
更新日期：2016-05-01 00:00:00
abstract：:The present report is an analysis of 93 patients (52 male; 41 female) treated in 1981-1983 for maxillofacial fractures sustained in bicycle accidents. These accidents accounted for 7.1% of all facial bone fractures treated during the same period. Most accidents were single vehicle accidents (88%) and took place during...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0300-9785(86)80005-9
更新日期：1986-02-01 00:00:00
abstract：:Mandibular reconstruction in osteoradionecrosis or salvage surgery can often be complicated by the lack of suitable recipient vessels in the ipsilateral neck and the associated requirement for significant extraoral skin reconstruction. The scapula tip with its long vascular pedicle and option of a chimeric soft tissue...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2017.02.1270
更新日期：2017-06-01 00:00:00
abstract：:A 7-year-old boy presented in whom a metaphyseal fibrous defect was diagnosed. The lesion was enucleated under local anesthesia. The postoperative course was uneventful and there have been no signs of recurrence as of 14 months after operation. Although rare, metaphyseal fibrous defect should be included in the differ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80834-3
更新日期：1997-04-01 00:00:00
abstract：:The tissue reaction following the use of glass-ionomer and amalgam, as retrograde filling materials was investigated in an experimental study using 8 monkeys. After apicectomy of the upper central incisors, amalgam and glass-ionomer cement was used at random as retrograde filling material. 2 animals at a time were sac...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(87)80085-1
更新日期：1987-08-01 00:00:00
abstract：:A case of incomplete midline cervical cleft of the upper neck is reported. It showed histological resemblance to a mature teratoma with three different germ-cell components, including cartilage, striated muscles, small salivary glands, and nerves. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80731-3
更新日期：1992-10-01 00:00:00
abstract：:The purpose of this prospective study was to evaluate survival and marginal bone loss at 10-year follow-up of implants inserted in completely edentulous arches and immediately loaded using multiple mucosa-supported stereolithographic surgical templates. The influence on marginal bone loss of the following variables wa...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.12.001
更新日期：2016-04-01 00:00:00
abstract：:Fractures of hyoid bone resulting from trauma other than strangulation are very rare, isolated hyoid bone fractures are even rarer, and occur more frequently in young individuals, and in men more than in women. A comprehensive review of the world literature, also two rare cases of isolated hyoid bone fractures induced...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2004.09.004
更新日期：2005-06-01 00:00:00
abstract：:The objective of this study was to improve the accuracy of diagnosis of inferior alveolar nerve (IAN) injury by determining degrees of nerve disturbance using the sensory nerve action potential (SNAP) and sensory nerve conduction velocity (SCV). Crush and partial and complete nerve amputation injuries were applied to ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.09.004
更新日期：2015-12-01 00:00:00
abstract：:The use of a combination of intraoperative cone-beam computed tomography (CBCT) and a navigation system via a spinal software platform for the navigated implantation of oral implants after microsurgical bone transfer is described. Intraoperative data sets were generated using Arcadis Orbic 3D (Siemens, Medical Solutio...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2007.06.011
更新日期：2008-01-01 00:00:00
abstract：:Previous studies have shown that impacted mandibular third molars (M3s) increase the risk of mandibular angle fractures and decrease the risk of mandibular condylar fractures. This study attempted to verify these relationships and identify the influence of mechanism and cause of injury. The incidence of fractures was ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2007.07.010
更新日期：2008-01-01 00:00:00
abstract：:The fibular free flap is the most widely used flap for jaw reconstruction. Flap contouring requires removal of bone excess in the proximal segment by a subperiosteal dissection, preserving vascular connections between the pedicle and the bone and leaving well vascularized periosteum attached to the vascular pedicle. A...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2008.01.023
更新日期：2008-07-01 00:00:00
abstract：:The purpose of this study was to assess whether genetic variation is a predictor for the development of medication-related osteonecrosis of the jaws (MRONJ) in patients receiving bisphosphonate therapy for various conditions. A systematic review based on the PRISMA guidelines was performed. A search strategy was devel...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2019.04.014
更新日期：2019-10-01 00:00:00
abstract：:An unusual case of endotracheal tube damage during Le Fort I osteotomy is presented. A minor change in design of the tube might prevent similar complications. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80755-6
更新日期：1992-12-01 00:00:00
abstract：:Paraffin sections of biopsy specimens obtained from 46 patients with oral squamous cell carcinomas were stained with both anti-peptide antibody against human Fas antigen and monoclonal mouse antibody against human proliferating cell nuclear antigen (PCNA). The patients received chemotherapy with a combination of carbo...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：:This article describes the experience with the endoscopically assisted fixation of the customized total temporomandibular joint (TMJ) prosthesis in TMJ Yang's system only through a modified preauricular approach. Twenty patients (23 joints) treated with the custom-made total TMJ prosthesis were retrospectively recruit...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2019.06.021
更新日期：2020-02-01 00:00:00
abstract：:The purpose of this study was to analyse the causes of venous compromise and flap failure in radial forearm free flap (RFFF) surgery for intraoral reconstruction. One hundred seventy-eight RFFF reconstructions were reviewed retrospectively for intraoral defects. Of the 13 flaps with venous obstruction, 9 flaps were sa...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2012.01.016
更新日期：2012-04-01 00:00:00
abstract：:Transfusion transmitted virus (TTV) is a new DNA virus found in patients with post-transfusion hepatitis. The prevalence of this virus among dental patients has not been reported, therefore, the prevalence of TTV infection in consecutive dental inpatients was evaluated. TTV DNA was assayed by the polymerase chain reac...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1054/ijom.2000.0224
更新日期：2003-04-01 00:00:00
abstract：:The aim of this three-dimensional finite element analysis study was to examine the biomechanical behaviour of dental implants and the surrounding bone under traumatic frontal force. Models were created of an edentulous atrophic mandible using cone beam computed tomography data from a patient; two titanium alloy implan...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.03.002
更新日期：2015-07-01 00:00:00
abstract：:Human papilloma virus (HPV) infection is controversial as a causative factor in oral tongue cancer. This study aimed to clarify whether HPV directly affects the carcinogenesis and biological behaviour of oral tongue cancer by analyzing HPV prevalence, the physical status of the virus and clinicopathological parameters...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2010.03.014
更新日期：2010-07-01 00:00:00
abstract：:Leiomyosarcomas are malignant tumours of smooth muscle origin. These tumours are very rare in the head and neck region. We report a case of metastatic uterine leiomyosarcoma masquerading as a primary sarcoma of the masseter muscle. We highlight the importance of considering the possibility of an unrecognised primary a...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.08.004
更新日期：2006-05-01 00:00:00
abstract：:Two hundred and sixty patients with oral and facial venous malformations received intralesional injections of either pingyangmycin, sodium morrhuate, or pingyangmycin alternating with sodium morrhuate. Results were rated excellent, good, fair, or poor, depending on clinical outcome. The prevalence of an "excellent" ra...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2003.10.003
更新日期：2004-07-01 00:00:00
