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Mechanisms of arterial thrombosis: foundation for therapy.

Abstract：

:Intravascular thrombus often occurs when the rupture or fissure of an atherosclerotic plaque exposes procoagulant elements lying below the plaque surface. This process of plaque rupture is the result both of passive mechanical forces and an active cell-mediated mechanism. Recently a number of investigators have developed imaging technologies based on magnetic resonance to characterize atherosclerotic lesions or the use of radioactively labeled platelets to dynamically visualize clot formation and lysis in vivo. These methods may permit early detection of developing thrombus, improve selection of treatment, and allow direct monitoring of the progression of antithrombotic therapy.

journal_name

Am Heart J

journal_title

American heart journal

authors

Fuster V

doi

10.1053/hj.1998.v135.90300

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

S361-6

issue

6 Pt 3 Su

eissn

0002-8703

issn

1097-6744

pii

a90300

journal_volume

135

pub_type

杂志文章,评审

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