Significance of Na+, K(+)-ATPase on intracellular accumulation of cis-diamminedichloroplatinum(II) in human non-small-cell but not in small-cell lung cancer cell lines.

abstract：:Grape seed extracts were more cytotoxic than grape peel extracts. Methanol and 70% methanol extracts of grape seed selectively killed two human oral tumor cell lines, more efficiently than human gingival fibroblasts. ESR spectroscopy revealed that these extracts produced radicals under alkaline conditions and enhanced...

journal_title：Anticancer research

authors： Shirataki Y,Kawase M,Saito S,Kurihara T,Tanaka W,Satoh K,Sakagami H,Motohashi N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIM:Hypoxia offers resistance to therapy in human solid tumors. The aim of the study was to investigate whether SN-38, the active metabolite of irinotecan, acts as a radiosensitizer through inhibition of hypoxia-inducible factor (HIF)-1α in the human colorectal cancer (CRC) cells. MATERIALS AND METHODS:HT29...

journal_title：Anticancer research

authors： Okuno T,Kawai K,Hata K,Murono K,Emoto S,Kaneko M,Sasaki K,Nishikawa T,Tanaka T,Nozawa H

更新日期：2018-06-01 00:00:00

abstract：:The effects of a bacterial vaccine, heat-killed Clostridium butyricum MII 588 cells, on the metastasis of B16-F10 melanoma in BDF1 mice was investigated. The vaccine stimulated natural killer (NK) cell cytotoxic activity against YAC-1 target cells, which peaked at 72 hr after the pretreatment, whereas maximum macropha...

journal_title：Anticancer research

authors： Chen HY,Wu SL,Yeh MY,Chen CF,Mikami Y,Wu JS

更新日期：1993-01-01 00:00:00

abstract：:The carcinogen Fe-NTA catalyzes the hydrogen peroxide-derived production of free radicals and possibly acts through a mechanism involving oxidative stress. Fermented papaya preparation (FPP) has been reported as a natural antioxidant able to prevent lipid peroxidation in vitro and in vivo. However, little is known abo...

journal_title：Anticancer research

authors： Rimbach G,Guo Q,Akiyama T,Matsugo S,Moini H,Virgili F,Packer L

更新日期：2000-09-01 00:00:00

abstract：:A human ovarian mesodermal mixed heterologous carcinoma, with a high content of cellular retinol-binding protein (CRBP), was used to study the effects of retinoid and hormonal treatment on tumour CRBP content, tumour growth rate, differentiation and turnover of CRBP. Tumour growth in general was accompanied by an incr...

journal_title：Anticancer research

authors： Wahlberg P,Fex G,Wennerberg J,Willén R

更新日期：1989-01-01 00:00:00

abstract：:Eighteen patients with Zollinger-Ellison syndrome were studied with 111In-pentetreotide SPECT in order to localize gastrinoma, the tumour responsible for this pathology. NMR imaging was also carried out. Eight patients were operated. 111In-pentetreotide was reinjected 4 hours before operation and the radioactivity of ...

journal_title：Anticancer research

authors： Scopinaro F,Schillaci O,Delle Fave G,Danieli R,Materia A,Tavolaro R,Angeletti S,Marignani M,Massa R,Gualdi G,Polettini E,Picardi V,Basso N

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Although in vitro and clinical studies indicate that overexpression of P-glycoprotein (Pgp), p53, or metallothionein (MT) is involved in modulating drug resistance/sensitivity of cancer cells, the clinical relevance of the overexpression remains to be elucidated. MATERIALS AND METHODS:In this paper the expr...

journal_title：Anticancer research

authors： Eid H,Géczi L,Mágori A,Bodrogi I,Institoris E,Bak M

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:5-Aminolevulinic acid (5-ALA) has already been applied clinically as a photosensitizer. In this study, sonodynamically induced selective antitumour effect of 5-ALA for deep-seated lesions was evaluated. MATERIALS AND METHODS:First, normal rat brains were sonicated via a transducer placed on the dural surfac...

journal_title：Anticancer research

authors： Ohmura T,Fukushima T,Shibaguchi H,Yoshizawa S,Inoue T,Kuroki M,Sasaki K,Umemura S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CCRT) is used to treat advanced head and neck cancer. The accuracy of evaluating lymph nodes metastases following CCRT is important for subsequent therapy. PATIENTS AND METHODS:Patients were divided into two groups, the complete response (CR) and the non-CR groups, as determine...

journal_title：Anticancer research

authors： Nishimura G,Matsuda H,Taguchi T,Takahashi M,Komatsu M,Sano D,Sakuma N,Arai Y,Takahashi H

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND/AIM:Pelvic exenteration is a radical procedure for certain advanced or recurrent gynaecological cancers, performed with curative or palliative intent. Its validity has evolved as operative mortality and morbidity have improved. This surgery was evaluated to determine the validity of these claims. PATIENTS A...

journal_title：Anticancer research

authors： Soeda S,Furukawa S,Sato T,Ueda M,Kamo N,Endo Y,Kojima M,Nomura S,Kataoka M,Fujita S,Endo H,Takahashi T,Watanabe T,Yamada H,Fujimori K

更新日期：2019-10-01 00:00:00

abstract：AIM:To evaluate the role of low mechanical index (MI) contrast-enhanced sonography (CEUS) for the characterization of small hepatocellular carcinomas (HCC) in cirrhotic patients by comparing the results to ultrafast dynamic gadolinium-enhanced magnetic resonance imaging (MRI) studies. MATERIALS AND METHODS:Between Sep...

journal_title：Anticancer research

authors： Giorgio A,De Stefano G,Coppola C,Ferraioli G,Esposito V,Di Sarno A,Giorgio V,De Stefano M,Sangiovanni V,Liorre G,Del Viscovo L

更新日期：2007-11-01 00:00:00

abstract：:The aim of this study was to evaluate the possible role in and contribution of antioxidant enzymes to bladder cancer (BC) etiology and recurrence after transurethral resection (TUR). We enrolled 40 patients with BC who underwent TUR and 100 sex- and age-matched healthy controls. The analysis was performed at diagnosis...

journal_title：Anticancer research

authors： Wieczorek E,Jablonowski Z,Tomasik B,Gromadzinska J,Jablonska E,Konecki T,Fendler W,Sosnowski M,Wasowicz W,Reszka E

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Macrophage colony stimulating factor (M-CSF) binds to colony-stimulating factor-1 receptor (CSF-1R) and thereby stimulates the proliferation, differentiation and behaviour of monocytes, macrophages and their bone marrow progenitors. Previous studies have suggested that high expression of these markers is cor...

journal_title：Anticancer research

authors： Richardsen E,Sørbye SW,Crowe JP,Yang JL,Busund LT

更新日期：2009-10-01 00:00:00

abstract：:When mouse resident peritoneal macrophages were cultured with PSK (Krestin), a protein-bound polysaccharide extracted from Coriolus versicolor, they became enlarged and elongated and expressed higher NBT-reducing activity. PSK stimulated the production of differentiation-inducing factor and cytotoxic factor by the mou...

journal_title：Anticancer research

authors： Kurakata Y,Sakagami H,Sato A,Kikuchi K,Takeda M,Asano K,Sato T

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND/AIM:The associations between emotional personality, proximity and authenticity in patient-physician communication during breast cancer (BC) consultations are rarely considered together in a prospective study. We, therefore, investigated emotional personality/proximity versus authenticity in patient-physician...

journal_title：Anticancer research

authors： Eskelinen M,Korhonen R,Selander T,Ollonen P

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Several studies have reported an association between Hashimoto's disease and thyroid carcinoma although the cause/effect relationship is still controversial. CASE REPORT:In this paper we report the case of a 38-year-old female who first presented with a clinical history of Hashimoto's thyroiditis. Ultrasoun...

journal_title：Anticancer research

authors： Pisani T,Bononi M,Pantellini F,Vecchione A,Giovagnoli MR

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The Notch inhibitors, γ-secretase inhibitors (GSIs), are promising candidates for molecular targeted therapy against leukemia. However, they show only limited effectiveness. We thought that the efficacy of GSIs might be improved by their combination with Hedgehog inhibitors and Wnt inhibitors because these s...

journal_title：Anticancer research

authors： Okuhashi Y,Itoh M,Nara N,Tohda S

更新日期：2011-03-01 00:00:00

abstract：:UGP (Urinary gonadotropin peptide) also know as urinary gonadotropin fragment (UGF) or the beta-core of hCG (c beta hCG), was identified as a peptide with a molecular weight of 10.5 kD, having the same amino acid sequence as the core section of the beta-subunit of human chorionic gonadotropin. UGP has been found in no...

journal_title：Anticancer research

authors： el-Ahmady O,Halim AB,Gad M,Walker R

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND/AIM:To study the changes of glioblastoma multiforme during chemoradiotherapy (CRT) and to evaluate the impact of changes on dosimetry and clinical outcomes. PATIENTS AND METHODS:Forty-three patients underwent volumetric imaging-based replanning. Prognostic factors and gross tumor volume changes in relation ...

journal_title：Anticancer research

authors： VÉgvÁry Z,DarÁzs B,Paczona V,Dobi Á,Reisz Z,Varga Z,Fodor E,CserhÁti A,OlÁh J,Kis D,BarzÓ P,HideghÉty K

更新日期：2020-08-01 00:00:00

abstract：:Experimental biochemical modulation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) with l-leucovorin (LV) was carried out using human gastric (H-111) and colon (Co-4) carcinoma xenografts serially transplanted into nude mice. Thirty-five or 70 mg/kg HCFU dissolved in 0.2 ml of 1% hydroxymethyl cellulose was administered po...

journal_title：Anticancer research

authors： Kubota T,Kase S,Furukawa T,Tanino H,Kuo TH,Saikawa Y,Nishibori H,Ishibiki K,Kitajima M,Mabuchi K

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Screening gastroscopic examinations were performed in a cohort of individuals at high risk for developing gastric carcinoma (GC). PATIENTS AND METHODS:Five gastric biopsies were obtained following the Houston schema. Five histological parameters of gastritis were investigated: acute gastritis, chronic gastr...

journal_title：Anticancer research

authors： Saieva C,Rubio CA,Nesi G,Zini E,Filomena A

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The authors report their experience in patients with adjuvant systemic 2-interferon with the aim of defining the effectiveness, side-effects, indications and limitations of this treatment. MATERIALS AND METHODS:From January 1989 to December 1996, 123 patients with genital, anorectal and perineal HPV lesions ...

journal_title：Anticancer research

authors： Scala M,Bonelli G,Gipponi M,Margarino G,Muzza A

更新日期：2002-03-01 00:00:00

abstract：:Adult lymphoblastic lymphoma (LBL) can be of T-cell or B-cell lineage. However, the clinical significance of immunophenotypes is largely unknown. We conducted a retrospective study to compare T-cell LBL with its B-cell counterpart. Between 1983 and 1995, 50 adult patients were diagnosed as LBL at National Taiwan Unive...

journal_title：Anticancer research

authors： Yeh KH,Cheng AL,Su IJ,Lin MT,Tien HF,Shen MC,Wang CH,Chen YC

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND/AIM:The toxicity of the proteasome inhibitor MG132 was tested alone and combined either with the topoisomerase I inhibitor topotecan or the topoisomerase II inhibitor etoposide against a panel of 18 cell lines representing six pediatric tumor types. MATERIALS AND METHODS:MG132, topotecan, etoposide and thei...

journal_title：Anticancer research

authors： Destanovic E,Boos J,Lanvers-Kaminsky C

更新日期：2018-07-01 00:00:00

abstract：AIM:We analyzed pentafecta outcomes [complication-free, continence, potency, negative surgical margins (NSM)], biochemical recurrence (BCR)-free] of 230 patients undergoing robotic-assisted radical prostatectomy (RARP) with bilateral neurovascular (NVB) preservation. PATIENTS AND METHODS:Patient outcomes (group I, cas...

journal_title：Anticancer research

authors： Ou YC,Yang CK,Kang HM,Chang KS,Wang J,Hung SW,Tung MC,Tewari AK,Patel VR

更新日期：2015-09-01 00:00:00

abstract：:The development and maintenance of testicular interstitial cell (IC) tumors under the conditions of low LH levels were examined in aged Fischer 344 rats, and the enzyme activities for androgen synthesis in the tumors were estimated. Sixty-week old rats received injections of an LH-RH agonist (LH-RHa) for 28 weeks or w...

journal_title：Anticancer research

authors： Chatani F,Nonoyama T,Sudo K,Miyajima H,Takeyama M,Takatsuka D,Mori H,Matsumoto K

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Granulosa cell tumors (GCT) are rare malignant neoplasms of the ovaries with, usually, indolent biological behavior. PATIENTS AND METHODS:The epidemiological, clinical and pathological features of 34 patients with adult GCT, from the registry of the HeCOG, were analyzed retrospectively for their prognostic ...

journal_title：Anticancer research

authors： Pectasides D,Papaxoinis G,Fountzilas G,Aravantinos G,Pectasides E,Mouratidou D,Economopoulos T,Andreadis Ch

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND/AIM:Androgen-androgen receptor (AR) signal is known as a powerful driver of prostate cancer progression. We previously reported the limitation of prostate-specific antigen (PSA) at diagnosis as a prognostic biomarker of prostate cancer. Although serum total testosterone (TT) level has been reported as a prog...

journal_title：Anticancer research

authors： Izumi K,Shigehara K,Nohara T,Narimoto K,Kadono Y,Mizokami A

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:We evaluated the results of chemosensitivity testing for gastric cancer using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay in terms of the correlation of chemosensitivity and clinicopathological findings. PATIENTS AND METHODS:We analyzed 435 consecutive patients with gastric c...

journal_title：Anticancer research

authors： Noguchi K,Iwahashi M,Tani M,Nakamura M,Nakamori M,Nakatani Y,Ueda K,Ishida K,Naka T,Ojima T,Hotta T,Mizobata S,Yamaue H

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Angiogenesis is involved in the development of cancer, promoting tumor growth, invasiveness and metastasis. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor. The present case control study was carried out, to determine whether there is an association between the VEGF -2578C > A polymor...

journal_title：Anticancer research

authors： Park HM,Hong SH,Kim JW,Oh D,Hwang SG,An HJ,Kim UK,Kim NK

更新日期：2007-07-01 00:00:00