Impact of epidermal thickness on purpura from the pulsed dye laser.

Abstract:

BACKGROUND AND OBJECTIVE:To clarify whether epidermal thickness is of importance to the purpuric reaction from treatment with the pulsed dye laser (PDL). STUDY DESIGN/MATERIALS AND METHODS:Fifteen fairly pigmented volunteers were laser treated in two test regions of varying epidermal thicknesses: normal buttock skin and ultraviolet B (UVB)-exposed buttock skin. Laser treatments were performed with the flashlamp-pumped PDL (585 nm). Fluences ranged from 3-6.5 J/cm2, spot size was 7 mm, and each volunteer received at least six fluences in each treatment region. Assessment of the response was based on clinical evaluation (threshold dose to purpura 10 minutes and 1 day after treatment) and skin reflectance-evaluated redness (1 and 6 days, 2 and 6 weeks after treatment). RESULTS:The total epidermal thickness differed between the unexposed buttock skin (median, 72.7 microm) and the UVB-exposed buttock skin (87.2 microm) (P < 0.01). There was no correlation between the epidermal thickness and the threshold dose to induce purpura 10 minutes and 1 day after laser exposure. Skin reflectance revealed no correlation between the epidermal thickness and the skin reflectance evaluated redness on 1, 6 days, and 2 weeks postoperatively. A dose-response relation was seen within the two test regions; 6 weeks after laser exposure, there was no remaining laser-induced skin redness. CONCLUSION:The epidermal thickness is unimportant to the purpuric reaction after PDL treatment.

journal_name

Lasers Surg Med

authors

Haedersdal M,Bech-Thomsen N,Therkildsen P,Poulsen T,Wulf HC

doi

10.1002/(sici)1096-9101(1998)22:3<159::aid-lsm3>3.

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

159-64

issue

3

eissn

0196-8092

issn

1096-9101

pii

10.1002/(SICI)1096-9101(1998)22:3<159::AID-LSM3>3.

journal_volume

22

pub_type

临床试验,杂志文章
  • Picosecond optical breakdown: tissue effects and reduction of collateral damage.

    abstract::The effects of picosecond laser-induced optical breakdown on tissue were investigated using high-intensity 40 ps Nd:YAG laser pulses at 1.06 microns. Tissue damage was evaluated using the corneal endothelium in vitro as a model system. Systematic studies were performed to determine the scaling of the tissue damage and...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,评审

    doi:10.1002/lsm.1900090302

    authors: Zysset B,Fujimoto JG,Puliafito CA,Birngruber R,Deutsch TF

    更新日期:1989-01-01 00:00:00

  • In vitro and in vivo optimization of infrared laser treatment for injured peripheral nerves.

    abstract:BACKGROUND AND OBJECTIVE:Repair of peripheral nerve injuries remains a major challenge in restorative medicine. Effective therapies that can be used in conjunction with surgical nerve repair to improve nerve regeneration and functional recovery are being actively investigated. It has been demonstrated by a number of pe...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22212

    authors: Anders JJ,Moges H,Wu X,Erbele ID,Alberico SL,Saidu EK,Smith JT,Pryor BA

    更新日期:2014-01-01 00:00:00

  • Nd:YAG laser-induced interstitial hyperthermia using a long frosted contact probe.

    abstract::The heating potential of a closed loop interstitial hyperthermia system employing 1,064 nm laser light in conjunction with a long frosted contact probe was investigated in hind limb muscle of anesthetized dogs. The laser system was an Nd:YAG surgical laser modified with a single channel thermometry unit, a computer, a...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900100106

    authors: Panjehpour M,Overholt BF,Milligan AJ,Swaggerty MW,Wilkinson JE,Klebanow ER

    更新日期:1990-01-01 00:00:00

  • Fiber-based laser speckle imaging for the detection of pulsatile flow.

    abstract:BACKGROUND AND OBJECTIVE:In endodontics, a major diagnostic challenge is the accurate assessment of pulp status. In this study, we designed and characterized a fiber-based laser speckle imaging system to study pulsatile blood flow in the tooth. STUDY DESIGN/MATERIALS AND METHODS:To take transilluminated laser speckle ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22370

    authors: Regan C,Yang BY,Mayzel KC,Ramirez-San-Juan JC,Wilder-Smith P,Choi B

    更新日期:2015-08-01 00:00:00

  • Laser recannalization of atheromatous vessels using fiber optics.

    abstract::A laser endoscope was devised using optic fibers in order to provide a means of visualization and removal of atheromatous plaques from arteries in cadavers and experimental animals. Atheromatous plaques were satisfactorily lased off in a few seconds, although contraction of lased vessels was observed. A self-focusing ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900040408

    authors: Ward H

    更新日期:1984-01-01 00:00:00

  • In vitro evaluation of ablation parameters of normal and fibrous aorta using smooth excimer laser coronary angioplasty.

    abstract::A modified excimer laser energy delivery system was used to irradiate 100 segments of normal and fibrous aorta in vitro. The laser beam was scanned into 8 fiber bundles consisting of 50 fibers each resulting in a reduction of the applied pulse energy. The total repetition rate was increased to 150 Hz in order to keep ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900130605

    authors: Xie DY,Hassenstein S,Oberhoff M,Hanke H,Baumbach A,Hohla K,Haase KK,Karsch KR

    更新日期:1993-01-01 00:00:00

  • Evaluation of a transparent perfluorodecalin-infused patch as an adjunct to laser-assisted tattoo removal: A pivotal trial.

    abstract:BACKGROUND AND OBJECTIVE:Laser-assisted treatment of tattoos is well recognized to produce opaque epidermal whitening that prevents multiple sequential passes during a single treatment session. The amount of epidermal whitening produced in association with the procedure can be minimized by topical application of perflu...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/lsm.22659

    authors: Biesman BS,Costner C

    更新日期:2017-04-01 00:00:00

  • Dentinal tubule penetration of AH Plus, iRoot SP, MTA fillapex, and guttaflow bioseal root canal sealers after different final irrigation procedures: A confocal microscopic study.

    abstract:BACKGROUND AND OBJECTIVE:Varied physical and chemical characteristic of root canal sealers and different irrigant agitation systems can influence the depth of penetration. The aim of this in vitro study was to use a laser scanning confocal microscope in order to assess the dentinal tubules penetration of various sealer...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22446

    authors: Akcay M,Arslan H,Durmus N,Mese M,Capar ID

    更新日期:2016-01-01 00:00:00

  • Strategies for the reduction of cerebral microembolism during transmyocardial laser revascularization.

    abstract:BACKGROUND AND OBJECTIVES:During transmyocardial laser revascularization (TMLR), multiple microembolic signals (MES) can be detected in cerebral arteries. We sought to characterize composition and clinical relevance of these MES and to evaluate strategies to reduce cerebral microembolization during TMLR. STUDY DESIGN/...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20030

    authors: Gerriets T,Grossherr M,Misfeld M,Nees U,Reusche E,Stolz E,Sievers HH,Kaps M,Kraatz EG

    更新日期:2004-01-01 00:00:00

  • Effect of the combination of laser excision and interstitial hyperthermia in palliative therapy of head and neck tumours in the advanced stage of the disease.

    abstract:BACKGROUND AND OBJECTIVES:We evaluated the potential of combining laser excision with laser interstitial hyperthermia in order to improve the quality of life of patients with 3rd or 4th stage malignant head and neck tumours. STUDY DESIGN/MATERIALS AND METHODS:To evaluate the quality of life, we used the 4th version of...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.10253

    authors: Smucler R,Mazánek J

    更新日期:2004-01-01 00:00:00

  • Argon laser treatment of superficial vascular lesions in children.

    abstract::The author's experience in the use of the argon laser in the treatment of superficial vascular lesions in children is reviewed. Deteriorating portwine stains, strawberry hemangiomas, other hemangiomas, telangiectasias, and other lesions are discussed. Their natural histories are discussed. Details are given regarding ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900060106

    authors: Hobby LW

    更新日期:1986-01-01 00:00:00

  • Erbium-YAG and holmium-YAG laser ablation of the lens.

    abstract::Er-YAG (2.9 microns, 200 microseconds pulsewidth) and Ho-YAG (2.12 microns, 250 microseconds pulsewidth) lasers were used to irradiate bovine crystalline lenses. Mass ablated increased with increasing fluence for both lasers and was greater for the Er-YAG than the Ho-YAG laser at all fluences. The mass loss vs. fluenc...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900150110

    authors: Ross BS,Puliafito CA

    更新日期:1994-01-01 00:00:00

  • Free electron laser infrared wavelength specificity for cutaneous contraction.

    abstract:BACKGROUND AND OBJECTIVE:Short pulsed and scanned CO(2) lasers that target water molecules are currently used for cutaneous resurfacing. These CO(2) resurfacing lasers produce acute cutaneous contraction, which can be quantitated as a measure of the laser's effect. We postulated that targeting the vibrational and rotat...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(1999)25:1<1::aid-lsm1>3.0.

    authors: Ellis DL,Weisberg NK,Chen JS,Stricklin GP,Reinisch L

    更新日期:1999-01-01 00:00:00

  • Dynamic pain after laser-assisted-Uvulo-palatoplasty (LAUP) can instantaneously be mitigated by topical regimens.

    abstract:BACKGROUND AND OBJECTIVES:Kenalog application onto surgical wounds has been used to control dynamic pain following Laser-Assisted-Uvulo-Palatoplasty (LAUP) with good results in our department. When the effect was sub-optimal, insufficient ointment over the superior-lateral corner of wounds were always noted. Fulfilling...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.21122

    authors: Li LP,Lee SS,Chuang AY,Niddam DM,Tung TH,Chen JK

    更新日期:2011-11-01 00:00:00

  • Protoporphyrin IX fluorescence and photobleaching during interstitial photodynamic therapy of malignant gliomas for early treatment prognosis.

    abstract:BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...

    journal_title:Lasers in surgery and medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/lsm.22126

    authors: Johansson A,Faber F,Kniebühler G,Stepp H,Sroka R,Egensperger R,Beyer W,Kreth FW

    更新日期:2013-04-01 00:00:00

  • New device for visual neodymium:YAG laser prostate ablation: acute and chronic canine evaluation.

    abstract::This canine study (n = 6) evaluated the acute and chronic effects of Nd:YAG laser prostatectomy using a Prolase II fiber. The Prolase II device consists of a 1,000 microns quartz fiber which directs a cone of Nd:YAG laser energy, at 45 degrees to the axis of the fiber, into the prostatic urethra under direct visual gu...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900150304

    authors: Kopchok GE,Back M,White RA,Cavaye DM,Peng SK,Moriel E,Rajfer J

    更新日期:1994-01-01 00:00:00

  • Traumatic tattoo removal: comparison of four treatment methods in an animal model with correlation to clinical experience.

    abstract::The acute or emergency treatment of traumatic tattoos has been based on the principles of immediate and thorough removal of all particles. The delayed treatment of traumatic tattoos has classically been with overgrafting or dermabrasion. We developed an animal model for traumatic tattoos. Two levels of wounds were mad...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900100208

    authors: Sunde D,Apfelberg DB,Sergott T

    更新日期:1990-01-01 00:00:00

  • Prevention of acute radiodermatitis by photobiomodulation: A randomized, placebo-controlled trial in breast cancer patients (TRANSDERMIS trial).

    abstract:OBJECTIVE:Acute radiodermatitis (RD) is a distressing and painful skin reaction that occurs in 95% of the patients undergoing radiotherapy (RT). The aim of this study was to evaluate the effectiveness of photobiomodulation therapy (PBMT) in the prevention of acute RD in breast cancer (BC) patients undergoing RT. METHO...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22804

    authors: Robijns J,Censabella S,Claes S,Pannekoeke L,Bussé L,Colson D,Kaminski I,Bulens P,Maes A,Noé L,Brosens M,Timmermans A,Lambrichts I,Somers V,Mebis J

    更新日期:2018-02-10 00:00:00

  • Increasing the efficiency of photodynamic therapy by improved light delivery and oxygen supply using an anticoagulant in a solid tumor model.

    abstract:BACKGROUND AND OBJECTIVE:The main factors in photodynamic therapy (PDT) are: photosensitizer retention, photon absorption, and oxygen supply. Each factor has its unique set of problems that poses limitation to the treatment. Both light delivery and oxygen supply are significant bottlenecks in PDT. Vascular closure duri...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20951

    authors: Yang L,Wei Y,Xing D,Chen Q

    更新日期:2010-09-01 00:00:00

  • Effect of the CO2 milliwatt laser on tensile strength of microsutures.

    abstract:BACKGROUND AND OBJECTIVE:Laser-assisted tissue repair is often accompanied by a high dehiscence rate, which may be due to alterations in suture material after laser exposure. The goal of this study was to investigate the effect of CO2 laser irradiation on the tensile strength of microsurgical suture material. STUDY DE...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(1997)20:1<64::aid-lsm10>3.

    authors: Menovsky T,Beek JF,van Gemert MJ

    更新日期:1997-01-01 00:00:00

  • Wound healing and collagen thermal damage in 7.5-microsec pulsed CO(2) laser skin incisions.

    abstract:BACKGROUND AND OBJECTIVE:Wound-healing delays caused by lateral thermal damage to tissue remain a drawback of CO(2) surgical lasers. This study compares the thermal damage and wound-healing properties of a 7.5-micros pulsed CO(2) laser with scalpel and continuous wave (CW) CO(2) laser incisions. STUDY DESIGN/MATERIALS...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(2000)26:1<22::aid-lsm5>3.0

    authors: Sanders DL,Reinisch L

    更新日期:2000-01-01 00:00:00

  • The anti-inflammatory mechanism of 635 nm light-emitting-diode irradiation compared with existing COX inhibitors.

    abstract:BACKGROUND AND OBJECTIVES:Inhibition of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti-inflammatory effects have been reported in clinical fields for specific wavelength irradiation d...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20533

    authors: Lim W,Lee S,Kim I,Chung M,Kim M,Lim H,Park J,Kim O,Choi H

    更新日期:2007-08-01 00:00:00

  • Influence of cavity preparation with Er:YAG Laser on enamel adjacent to restorations submitted to cariogenic challenge in situ: a polarized light microscopic analysis.

    abstract:BACKGROUND AND OBJECTIVES:Er:YAG laser has been used for caries removal and cavity preparation, using ablative parameters. Its effect on the margins of restorations submitted to cariogenic challenge has not yet been sufficiently investigated. The aim of this study was to assess the enamel adjacent to restored Er:YAG la...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/lsm.20684

    authors: Chimello DT,Serra MC,Rodrigues AL Jr,Pécora JD,Corona SA

    更新日期:2008-11-01 00:00:00

  • Effect of helium-neon and infrared laser irradiation on wound healing in rabbits.

    abstract::We examined the biostimulating effects of helium-neon laser radiation (HeNe; 632.8 nm), pulsed infrared laser radiation (IR; 904 nm), and the two combined on skin wound healing in New Zealand white rabbits. Seventy-two rabbits received either 1) no exposure, 2) 1.65 J/cm2 HeNe, 3) 8.25 J/cm2 pulsed IR, or 4) both HeNe...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900090111

    authors: Braverman B,McCarthy RJ,Ivankovich AD,Forde DE,Overfield M,Bapna MS

    更新日期:1989-01-01 00:00:00

  • Water-jet-cooled Nd:YAG laser coagulation: selective destruction of rat liver metastases.

    abstract::The photocoagulating properties of the water-jet-cooled Nd:YAG laser (1,064 nm) have been studied in a rat tumor model. A colon carcinoma CC531 was implanted in the liver; 20 days after inoculation, laser therapy was performed with 600 J, 850 J, 1,200 J, 1,700 J, or 2,400 J at a power setting of either 10 or 20 W. Liv...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900110510

    authors: Van Hillegersberg R,Kort WJ,ten Kate FJ,Terpstra OT

    更新日期:1991-01-01 00:00:00

  • Targeting of sebaceous glands to treat acne by micro-insulated needles with radio frequency in a rabbit ear model.

    abstract:BACKGROUND AND OBJECTIVES:Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22599

    authors: Kwon TR,Choi EJ,Oh CT,Bak DH,Im SI,Ko EJ,Hong HK,Choi YS,Seok J,Choi SY,Ahn GY,Kim BJ

    更新日期:2017-04-01 00:00:00

  • Fractional photothermolysis: current and future applications.

    abstract::Ablative lasers (CO2 and Er:YAG) provide the greatest improvement in photoaging, but significant adverse effects limit their use. Nonablative lasers have reduced adverse effects, but limited efficacy. Fractional photothermolysis (FP) produces arrays of microscopic thermal wounds called microscopic treatment zones (MTZ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20310

    authors: Geronemus RG

    更新日期:2006-03-01 00:00:00

  • Treatment of infantile hemangiomas with the 595-nm pulsed dye laser using different pulse widths in an Asian population.

    abstract:INTRODUCTION:The pulsed dye laser (PDL) using varying fluences and pulse durations have been used to treat hemangiomas. This study aims to examine the efficacy and safety of the 595-nm PDL for the treatment of infantile hemangiomas using short (1.5-3 milliseconds) versus long (10 milliseconds) pulse durations and high ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.21159

    authors: Tay YK,Tan SK

    更新日期:2012-02-01 00:00:00

  • HeNe laser irradiation delivered transcutaneously: its effect on the sciatic nerve of rats.

    abstract::For our study of the effect of low energy laser irradiation (LELI) on living tissue we used HeNe laser on rats. The exponential absorption was reaffirmed in the living tissues overlying the sciatic nerve. An optimal range of energy between 3.5 and 7 J--associated with energy concentration of 4-10 J/cm2 delivered trans...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900060502

    authors: Nissan M,Rochkind S,Razon N,Bartal A

    更新日期:1986-01-01 00:00:00

  • Pulmonary blast injury in mice: a novel model for studying blast injury in the laboratory using laser-induced stress waves.

    abstract:BACKGROUND AND OBJECTIVES:Primary blast injury is produced by shock waves. Blast injuries to lungs are extremely critical threats to survival, but their etiology is largely undefined. The majority of animal models for these injuries use explosive or complex experimental settings, limiting the laboratory study of blast ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20899

    authors: Satoh Y,Sato S,Saitoh D,Tokuno S,Hatano B,Shimokawaji T,Kobayashi H,Takishima K

    更新日期:2010-04-01 00:00:00