[Lipid and non-lipid effects of enduracin in patients with arterial hypertension].

Abstract:

AIM:To analyze lipid and non-lipid effects of 6-month administration of enduracine in patients with marked dislipoproteinemia suffering from arterial hypertension with ischemic heart disease or without it. MATERIALS AND METHODS:40 hypertensive patients (27 males and 13 females, mean age 52.43 +/- 1.68 years) entered the study of enduracine effects. Most of them received enduracine for 6 months in a dose 1500 mg/day. Lipids levels were measured in all the patients. Blood flow along major brain arteries was determined at transcranial dopplerography in 23 patients. RESULTS:A 6-month course of enduracine in a dose 1500 mg/day promoted normalization of serum lipid spectrum, vascular tonicity and reactivity of cerebral arteries, produced a mild hypotensive effect. CONCLUSION:Endurance (a long-acting form of nicotinic acid) has favourable lipid and non-lipid effects in patients with dislipoproteinemias and arterial hypertension in the presence or absence of ischemic heart disease.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Smolenskaia OG,Kazakov IaE,Barats SS

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

23-7

issue

8

eissn

0040-3660

issn

2309-5342

journal_volume

71

pub_type

杂志文章
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  • [Relationship between district polyclinic internists and cardiologists in the follow-up of patients with ischemic heart disease].

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  • [Apolipoprotein E and activity of cholesterol esters transport in type IIA and IIB hyperlipoproteinemia].

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  • [Cholesterosis of the gall bladder and atherogenic dyslipidemia: etiology, pathogenesis, clinical symptoms, diagnosis and treatment].

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  • [Epidemiology of multiple myeloma in city Moscow].

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