Abstract：
:In the treatment of malignant tumors regional lymphadenectomy is used for two purposes. It is used partly for staging the regional lymph nodes which is a significant and independent prognostic factor and determines the need for adjuvant oncologic treatment and partly for achieving locoregional disease control. Removal of tumor-free lymph nodes by regional lymph node clearance is unnecessary according to our current knowledge. Since the sensitivity and specificity of non-invasive clinical examinations are insufficient in predicting the nodal status the histological study of the regional lymph nodes cannot be abandoned. A new and minimally invasive surgical procedure, the mapping and removal of the first tumor draining lymph node, the sentinel node provides the possibility of pathological nodal staging without performing formal lymphadenectomy. Mapping of the sentinel node can be performed by the use of a radioisotope and intraoperative hand-held gamma-probe or a vital blue dye or a combination of these two. This latter method was used by the authors in 73 patients (25 with malignant melanoma and 48 with breast cancer). Sentinel lymph node biopsy was performed successfully in 92% of patients with melanoma and 90% of patients with breast cancer. In three breast cancer patients the sentinel node inaccurately predicted the axillary status as negative, but is was in 93% accurate in predicting the histologic nodal state. According to our preliminary experiences intraoperative gamma-probe guided sentinel lymph node biopsy is considered a feasible procedure in both malignant melanoma and breast cancer. More experiences are needed before introducing this method in the routine clinical practice.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Péley G,Sinkovics I,Liszkay G,Tóth J,Péter I,Farkas E,Téglás M,Hrívó A,Füzy M,Gilde K,Köves Isubject
Has Abstractpub_date
1999-10-17 00:00:00pages
2331-8issue
42eissn
0030-6002issn
1788-6120journal_volume
140pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract：:Since the eighties of the last century hormone content was justified in immune cells (lymphocytes, granulocytes, monocytes, macrophages and mast cells), which produce, store and secrete these hormones. Although the amount of these materials in immune cells is relatively small, the mass of the producers (immune cells) ...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2011.29122
更新日期：2011-05-15 00:00:00
abstract：:Two cases of arrhythmogenic right ventricular dysplasia are described. The most important clinical features of the disease are malignant ventricular arrhythmia and sudden death. It is characterized by the loss of right ventricular musculature and by the fatty and connective tissue infiltration of the right ventricular...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1993-12-19 00:00:00
abstract：UNLABELLED:The exocrine pancreatic function was examined in 20 patient without any detectable gastrointestinal disorder. We used 1 g 4(N-acetyl-L-thyrosil) aminobenzoic acid (ALTAB) an Lundh's test meal containing 25 g lactose, and the test was repeated with 3 g lactase (Galantase). The urine was collected for 6 hours ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1990-03-25 00:00:00
abstract：:The "gold standard" of the prevention of atrial fibrillation related thromboembolic events is anticoagulation therapy with oral vitamin K antagonists. A certain proportion of high-risk patients with atrial fibrillation are not receiving effective antithrombotic therapy because of problems associated with its use. Reso...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2013.29550
更新日期：2013-02-17 00:00:00
abstract：:Numerous antihypertensive drugs exist with different modes of action, which have a really effective impact on hypertension. The life expectancy of hypertensive patients is known to depend on the degree of damage caused to their target organs by the hypertension itself. Cardiovascular hypertrophy and its complications ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1996-07-21 00:00:00
abstract：:Authors present two cases. One of their patient was followed for 30 years. They discuss the pathological characters and diagnostic difficulties of the disease. They have observed that with radical operations of--according to necessity--serial surgical interventions the outcome of patients can be properly controlled ag...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1993-04-04 00:00:00
abstract：INTRODUCTION:Since the celebration of the 20th anniversary of the first heart transplantation in Hungary in 2012 the emerging need for modern heart failure management via mechanical circulatory support has evolved. In May 2012 the opening of a new heart failure and transplant unit with 9 beds together with the procurem...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2015.30115
更新日期：2015-03-29 00:00:00
abstract：:A rare form of pause dependent form of torsade de pointes ventricular tachycardia and T-wave alternans is reported. The life-threatening ventricular arrhythmia was associated with left sided intracerebral hemorrhage and elevated CKMB mass and Troponin T (0.14 ng/ml). The possible pathomechanism of torsade de pointes t...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2003-10-19 00:00:00
abstract：INTRODUCTION:Gleason grading is the most common method of prostate cancer classification. AIM:The aim of the authors was to assess the reproducibility of Gleason grading among pathologists using the same needle biopsy samples. METHOD:23 pathologists examined 37 prostate cancer biopsies stained with hematoxylin and eo...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2013.29659
更新日期：2013-08-04 00:00:00
abstract：UNLABELLED:INTRODUCTION, AIMS: In spring of 2000 a national survey was conducted on the diagnostic and therapeutic attitudes of Hungarian family practitioners concerning Helicobacter pylori. RESULTS:Based on responses, endoscopy, urea breath test and serology are easily available to 98, 42 and 48% of family practition...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2002-06-30 00:00:00
abstract：:Low HDL cholesterol level is an independent risk factor in the cardivascular diseases and the therapeutic aim is to increase this. In high risk patients (cardiovascular disease-, diabetic- or metabolic syndrome patients), the target value of HDL cholesterol is more than 1,0 mmol/l in males and 1,3 mmol/l in females. T...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-26 00:00:00
abstract：:The case of a chronic myelogenous leukemia (CML) starting in an unusual form in a young woman is reported. Rapidly progressing icterus was the first and leading symptom of the disease. Simultaneously with the exclusion of the possibility of hepatitis and extrahepatic obstruction of the bile duct the qualitative blood ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1989-10-22 00:00:00
abstract：:In recent years, the question of hemoglobin (Hb) stability in patients with chronic renal failure has attracted the interest of medical experts. One of the most important reasons behind this interest is that maintaining the hemoglobin level within the new narrower target range is highly challenging in clinical practic...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2008.28471
更新日期：2008-10-12 00:00:00
abstract：:The author expounds the reason of travellers' disease (bacterial-, viral-, parazitic infections). the most recently recognized pathogens (yersinia, campylobacterium, Clostridium perfringens, B. cereus, Cryptosporidium, rotavirus etc.), as well as the newest data on the pathomechanism of enteric infections have been sh...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1998-07-12 00:00:00
abstract：:Chronic obstructive pulmonary disease is often associated with cardiovascular diseases, such as pulmonary hypertension, ischemic heart disease, arrhythmias or heart failure. These co-morbidities may cause diagnostic or therapeutic difficulties and significantly worsen the morbidity and mortality of patients with chron...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2014.29989
更新日期：2014-09-14 00:00:00
abstract：:Introduction: Recently published unfavourable results of endoscopic radical surgery for early-stage cervical cancer compared to open surgery raises the need for auditing treatment results of endoscopic staging surgery for endometrial cancer. Aim: Comparison of progression-free and overall survival (PFS and OS) between...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/650.2020.31675
更新日期：2020-03-01 00:00:00
abstract：:The endothelium is a major regulator of vascular tone, releasing vasoconstrictive (endothelin, cyclooxigenase-dependent factors, including prostanoids and oxygen free radicals) and vasodilating (endothelium--derived nitric oxid, endothelium--derived hyperpolarizing factor) mediators. These biologically active substanc...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2001-08-05 00:00:00
abstract：:The common European viper is widespread throughout Europe. In Hungary it can be found mainly in the Zemplén Mountains, on the upper course of the Tisza River, and Zala and Somogy counties. Viper's bite is one of the rarest injuries that requires emergency medical care. The venom contains polypeptides and hydrolytic en...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2011.29213
更新日期：2011-10-09 00:00:00
abstract：:Due to improving results in congenital heart surgery, the number of adult patients with congenital heart defect is increasing. The question is: what kind of problems can be managed in this patient-group? The authors review the different problems of management of congenital heart defects in adults based on national and...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2015.30072
更新日期：2015-01-18 00:00:00
abstract：:Authors performed a comparative study of replacement of captopril (2-3x daily) therapy with once daily enalapril. Blood pressure was measured by 24-hour ambulatory monitoring. The study enrolled 62 patients with mild to moderate hypertension. Captopril was previously administered 2-4 times per day, in mean dose of 74....
journal_title：Orvosi hetilap
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-12-22 00:00:00
abstract：BACKGROUND:The risk of colorectal carcinoma development is elevated in chronic, longstanding ulcerative colitis. The changes of such regenerative and immortalizing pathways caused by the inflammatory process that are proved to be carcinogenic in other human tissues have not been fully and uniformly described. Aim of th...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2006-09-24 00:00:00
abstract：:Follicular lymphoma is one of the most common indolent nodal non-Hodgkin's lymphomas. The follicular lymphoma should be differentiated from other nodal non-germinal centre derived lymphomas. Since bcl-2 gene translocation can be detected in 80-90% of the cases, it could be used for the confirmation of the diagnosis, m...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-16 00:00:00
abstract：:Authors performed an open, crossover, multicenter study of oral cilazapril versus previous captopril treatment in mild to moderate hypertension. The treatment of the 100 outpatients on daily three or four times captopril was found ineffective, or in some cases side effects or non compliance necessitated a switch to a ...
journal_title：Orvosi hetilap
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1995-10-15 00:00:00
abstract：:A newborn is described, who was born in term with 3250 g weight, after intrauterine hypoxia. She was born with vacuum extraction, and suffered from birth trauma and intrauterine infection. At age of one day manifested an eclampsia, which was hardly diminishable. The serum Na level was 118 mmol/l. Bilateral adrenal apo...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-10 00:00:00
abstract：:In Szabolcs-Szatmár county between January 1 1983 and December 31, 1987, 465 new cases of adult malignant haematologic diseases were registered by authors. The authors present the yearly distribution of cases, and analyse the main types and characteristics of the disease entity. According to their data the epidemiolog...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1990-02-25 00:00:00
abstract：INTRODUCTION:The EuroHOPE FP7 project analysed the effectiveness and efficiency of stroke care between 2010 and 2014. AIM:The study introduces Hungarian data in comparison with international results and explores the causes of differences. METHOD:The analysis was performed on data available from regular data collectio...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/650.2016.30558
更新日期：2016-10-01 00:00:00
abstract：:The gastrointestinal mucosa is one of the principal portal of entry in systemic fungal infections. Esophagitis is the most frequent among the fungal infections of the gastrointestinal tract. The etiologic factors of fungal infections are various Candida species, most frequently Candida albicans. Due to the large numbe...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-21 00:00:00
abstract：:Diabetes diagnosed in the so-called middle age of life is debated from the typological point of view. The authors investigated 45 diabetics, whose disease had been diagnosed between the age of 30-45 years. As a result of their observations they state that diabetes in this age range is heterogenous. Patients can be cla...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-07 00:00:00
abstract：:The authors account of the application of the Omiderm folie in connection with 29 cases. The transparent polyurethan skin substitute was used in dermatological diseases when presenting extensive shortage of tissue or for covering the half-thick skin's donor areas and for the treatment of deep second degree burns. The ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1991-06-02 00:00:00
abstract：BACKGROUND:A growing body of evidence in the international literature suggests that the prevalence of psychiatric morbidity including suicide is high among physicians. In addition, data published by Hungarian researchers in the early 1990-ies showed high prevalence of somatic morbidity in this population. Based on thes...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2005-06-26 00:00:00
