[Pathogenetic significance of cholesterol-containing immune complexes and lipid peroxidation in ischemic heart disease].

Abstract:

AIM:To ascertain a relationship between cholesterol content in circulating immune complexes (CIC) and plasm lipid peroxidation (LPO) in patients with ischemic heart disease (IHD). MATERIALS AND METHODS:Blood samples from 33 IHD patients 23 of which had a history of myocardial infarction and from 8 healthy subjects were examined for total cholesterol, high and low density lipoproteins cholesterol, CIC, the ability of blood serum to induce free radicals, superoxide dismutase. RESULTS:A statistically significant positive correlation was found between CIC cholesterol level and content of free radicals while a negative correlation existed between superoxide dismutase activity and high density lipoprotein cholesterol level in blood plasm of healthy individuals and patients with IHD. After myocardial infarction an inversion of the above parameters was seen as a result of disorders in both antioxidant and immune systems. CONCLUSION:The level of both LPO and CIC cholesterol, their interaction are important atherogenic factors in development of IHD.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Urazgil'deeva SA,Shatalina LV,Gurevich VS

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

8-10

issue

12

eissn

0040-3660

issn

2309-5342

journal_volume

71

pub_type

杂志文章
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    doi:

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  • [The role of inflammation factors in development of acute coronary syndrome in patients with type 2 diabetes mellitus and impaired glucose tolerance].

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    authors: Polozhentsev SD,Tulupov AN,Gurevich KIa,Krivozubov EF

    更新日期:1991-01-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Il'chenko IN,Tubol IB,Zhukovskiĭ GS,Dorofeeva TG,Propirnyĭ GV

    更新日期:1989-01-01 00:00:00

  • [The clinical significance of the liver glutathione system in chronic lesions].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

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    authors: Loginov AS,Matiushin BN,Tkachev VD

    更新日期:1997-01-01 00:00:00

  • [Changes in fatty acids content in blood red cells of patients with iron-deficiency anemia treated with sorbifer and mildronate].

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  • [Circular disorders in the common carotid artery bed and associated psychovegetative and hemodynamic disturbances in hypertensive patients].

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    authors: Shpak LV,Kolbasnikov SV

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  • [Experience in using transesophageal electrocardiostimulation in emergency heart rhythm disorders].

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    authors: Egorov DF,Sapozhnikov IR,Vygovskiĭ AB,Domashenko AA,Zhukov OS

    更新日期:1987-01-01 00:00:00

  • [A current model for predicting the risk of cardiovascular diseases in patients with type 2 diabetes mellitus].

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    doi:

    authors: Biriukova EV

    更新日期:2012-01-01 00:00:00

  • [Apolipoprotein E and activity of cholesterol esters transport in type IIA and IIB hyperlipoproteinemia].

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    authors: Tvorogova MG,Rozhkova TA,Semenova OA,Lupanov VP,Nuraliev EIu,Kukharchuk VV,Titov VN

    更新日期:1997-01-01 00:00:00

  • [Cardiac changes in hereditary spinocerebellar degenerations].

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  • [Ethical problems in predicting health status: the use of disease risk factors].

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    authors: Vlasov VV

    更新日期:1994-01-01 00:00:00

  • [DNA-abzymes and their clinical significance in systemic lupus erythematosis].

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    pub_type: 杂志文章,多中心研究

    doi:

    authors: Suchkov SV,Gabibov AG,Alekberova ZS,Gnuchev NV

    更新日期:2001-01-01 00:00:00

  • [Efferent therapy in the combined treatment of sepsis].

    abstract::Efferent therapy (hemosplenosorption, plasmapheresis, autologous blood radiation) was used in multimodality treatment of 45 patients with sepsis. The therapy exerted a beneficial effect on the disease, favoured the elimination of or minimized intoxication, normalized hemostasis and immunity. Indications for use of hem...

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    doi:

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  • [Protein metabolism in patients with duodenal ulcers and mathematical modeling of its disorders].

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    doi:

    authors: Khachiev GL,Ovchinnikova IV,Tursunbaev A

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  • [Neurological aspects of multiple myeloma].

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    pub_type: 杂志文章

    doi:

    authors: Golenkov AK,Guseva LL,Zlatkina AR,Lagutina TS,Markova VI

    更新日期:1986-01-01 00:00:00