Abstract:
:The detailed genomic organization of a gene-dense region at human chromosome 12p13, spanning 223 kb of contiguous sequence, was determined. This region is composed of 20 genes and several other expressed sequences. Experimental tools including RT-PCR and cDNA sequencing, combined with gene prediction programs, were utilized in the analysis of the sequence. Various computer software programs were employed for sequence similarity searches and functional predictions. The high number of genes with diverse functions and complex transcriptional patterns make this region ideal for addressing challenges of gene discovery and genomic characterization amenable to large-scale sequence analysis.
journal_name
Genome Resjournal_title
Genome researchauthors
Ansari-Lari MA,Shen Y,Muzny DM,Lee W,Gibbs RAdoi
10.1101/gr.7.3.268subject
Has Abstractpub_date
1997-03-01 00:00:00pages
268-80issue
3eissn
1088-9051issn
1549-5469journal_volume
7pub_type
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