Risk factors for oral human papillomavirus in adults infected and not infected with human immunodeficiency virus.

Abstract:

BACKGROUND AND OBJECTIVES:To investigate in a cross-sectional study the determinants of oral human papillomavirus infection in 287 individuals who are sexually active. GOAL:To assess prevalence as well as risk factors for oral human papillomavirus infection. STUDY DESIGN:One hundred seventy-eight human immunodeficiency virus-seropositive (158 men and 20 women) and 109 human immunodeficiency virus-negative (73 men and 36 women) individuals were recruited consecutively from sexually transmitted disease-human immunodeficiency virus clinics and gastrointestinal endoscopy clinics. Oral brushings were tested with the L1 consensus polymerase chain reaction assay for human papillomavirus detection. RESULTS:Human papillomavirus DNA was detected in 32 (11.2%) of 287 individuals. Associated with oral human papillomavirus infection on univariate analyses were human immunodeficiency virus infection (odds ratio, 6.9; 95% confidence interval, 2.0-23.2), homosexuality (odds ratio, 3.7; 95% confidence interval, 1.5-9.4), unprotected oral sex (odds ratio, 5.5; 95% confidence interval, 1.6-18.4), syphilis (odds ratio, 2.5; 95% confidence interval, 1.1-6.3), gonorrhea (odds ratio, 4.2; 95% confidence interval, 1.9-9.1), Chlamydia trachomatis (odds ratio, 4.4; 95% confidence interval, 1.8-10.6), and genital herpes (odds ratio, 2.9; 95% confidence interval, 1.3-6.5). Human immunodeficiency virus infection and C. trachomatis were independently predictive of human papillomavirus infection in multivariate stepwise logistic regression.

journal_name

Sex Transm Dis

authors

Coutlée F,Trottier AM,Ghattas G,Leduc R,Toma E,Sanche G,Rodrigues I,Turmel B,Allaire G,Ghadirian P

doi

10.1097/00007435-199701000-00006

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

23-31

issue

1

eissn

0148-5717

issn

1537-4521

journal_volume

24

pub_type

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